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The Craft of Writing a Strong Hypothesis

Deeptanshu D

Table of Contents

Writing a hypothesis is one of the essential elements of a scientific research paper. It needs to be to the point, clearly communicating what your research is trying to accomplish. A blurry, drawn-out, or complexly-structured hypothesis can confuse your readers. Or worse, the editor and peer reviewers.

A captivating hypothesis is not too intricate. This blog will take you through the process so that, by the end of it, you have a better idea of how to convey your research paper's intent in just one sentence.

What is a Hypothesis?

The first step in your scientific endeavor, a hypothesis, is a strong, concise statement that forms the basis of your research. It is not the same as a thesis statement , which is a brief summary of your research paper .

The sole purpose of a hypothesis is to predict your paper's findings, data, and conclusion. It comes from a place of curiosity and intuition . When you write a hypothesis, you're essentially making an educated guess based on scientific prejudices and evidence, which is further proven or disproven through the scientific method.

The reason for undertaking research is to observe a specific phenomenon. A hypothesis, therefore, lays out what the said phenomenon is. And it does so through two variables, an independent and dependent variable.

The independent variable is the cause behind the observation, while the dependent variable is the effect of the cause. A good example of this is “mixing red and blue forms purple.” In this hypothesis, mixing red and blue is the independent variable as you're combining the two colors at your own will. The formation of purple is the dependent variable as, in this case, it is conditional to the independent variable.

Different Types of Hypotheses‌

Types-of-hypotheses

Types of hypotheses

Some would stand by the notion that there are only two types of hypotheses: a Null hypothesis and an Alternative hypothesis. While that may have some truth to it, it would be better to fully distinguish the most common forms as these terms come up so often, which might leave you out of context.

Apart from Null and Alternative, there are Complex, Simple, Directional, Non-Directional, Statistical, and Associative and casual hypotheses. They don't necessarily have to be exclusive, as one hypothesis can tick many boxes, but knowing the distinctions between them will make it easier for you to construct your own.

1. Null hypothesis

A null hypothesis proposes no relationship between two variables. Denoted by H 0 , it is a negative statement like “Attending physiotherapy sessions does not affect athletes' on-field performance.” Here, the author claims physiotherapy sessions have no effect on on-field performances. Even if there is, it's only a coincidence.

2. Alternative hypothesis

Considered to be the opposite of a null hypothesis, an alternative hypothesis is donated as H1 or Ha. It explicitly states that the dependent variable affects the independent variable. A good  alternative hypothesis example is “Attending physiotherapy sessions improves athletes' on-field performance.” or “Water evaporates at 100 °C. ” The alternative hypothesis further branches into directional and non-directional.

  • Directional hypothesis: A hypothesis that states the result would be either positive or negative is called directional hypothesis. It accompanies H1 with either the ‘<' or ‘>' sign.
  • Non-directional hypothesis: A non-directional hypothesis only claims an effect on the dependent variable. It does not clarify whether the result would be positive or negative. The sign for a non-directional hypothesis is ‘≠.'

3. Simple hypothesis

A simple hypothesis is a statement made to reflect the relation between exactly two variables. One independent and one dependent. Consider the example, “Smoking is a prominent cause of lung cancer." The dependent variable, lung cancer, is dependent on the independent variable, smoking.

4. Complex hypothesis

In contrast to a simple hypothesis, a complex hypothesis implies the relationship between multiple independent and dependent variables. For instance, “Individuals who eat more fruits tend to have higher immunity, lesser cholesterol, and high metabolism.” The independent variable is eating more fruits, while the dependent variables are higher immunity, lesser cholesterol, and high metabolism.

5. Associative and casual hypothesis

Associative and casual hypotheses don't exhibit how many variables there will be. They define the relationship between the variables. In an associative hypothesis, changing any one variable, dependent or independent, affects others. In a casual hypothesis, the independent variable directly affects the dependent.

6. Empirical hypothesis

Also referred to as the working hypothesis, an empirical hypothesis claims a theory's validation via experiments and observation. This way, the statement appears justifiable and different from a wild guess.

Say, the hypothesis is “Women who take iron tablets face a lesser risk of anemia than those who take vitamin B12.” This is an example of an empirical hypothesis where the researcher  the statement after assessing a group of women who take iron tablets and charting the findings.

7. Statistical hypothesis

The point of a statistical hypothesis is to test an already existing hypothesis by studying a population sample. Hypothesis like “44% of the Indian population belong in the age group of 22-27.” leverage evidence to prove or disprove a particular statement.

Characteristics of a Good Hypothesis

Writing a hypothesis is essential as it can make or break your research for you. That includes your chances of getting published in a journal. So when you're designing one, keep an eye out for these pointers:

  • A research hypothesis has to be simple yet clear to look justifiable enough.
  • It has to be testable — your research would be rendered pointless if too far-fetched into reality or limited by technology.
  • It has to be precise about the results —what you are trying to do and achieve through it should come out in your hypothesis.
  • A research hypothesis should be self-explanatory, leaving no doubt in the reader's mind.
  • If you are developing a relational hypothesis, you need to include the variables and establish an appropriate relationship among them.
  • A hypothesis must keep and reflect the scope for further investigations and experiments.

Separating a Hypothesis from a Prediction

Outside of academia, hypothesis and prediction are often used interchangeably. In research writing, this is not only confusing but also incorrect. And although a hypothesis and prediction are guesses at their core, there are many differences between them.

A hypothesis is an educated guess or even a testable prediction validated through research. It aims to analyze the gathered evidence and facts to define a relationship between variables and put forth a logical explanation behind the nature of events.

Predictions are assumptions or expected outcomes made without any backing evidence. They are more fictionally inclined regardless of where they originate from.

For this reason, a hypothesis holds much more weight than a prediction. It sticks to the scientific method rather than pure guesswork. "Planets revolve around the Sun." is an example of a hypothesis as it is previous knowledge and observed trends. Additionally, we can test it through the scientific method.

Whereas "COVID-19 will be eradicated by 2030." is a prediction. Even though it results from past trends, we can't prove or disprove it. So, the only way this gets validated is to wait and watch if COVID-19 cases end by 2030.

Finally, How to Write a Hypothesis

Quick-tips-on-how-to-write-a-hypothesis

Quick tips on writing a hypothesis

1.  Be clear about your research question

A hypothesis should instantly address the research question or the problem statement. To do so, you need to ask a question. Understand the constraints of your undertaken research topic and then formulate a simple and topic-centric problem. Only after that can you develop a hypothesis and further test for evidence.

2. Carry out a recce

Once you have your research's foundation laid out, it would be best to conduct preliminary research. Go through previous theories, academic papers, data, and experiments before you start curating your research hypothesis. It will give you an idea of your hypothesis's viability or originality.

Making use of references from relevant research papers helps draft a good research hypothesis. SciSpace Discover offers a repository of over 270 million research papers to browse through and gain a deeper understanding of related studies on a particular topic. Additionally, you can use SciSpace Copilot , your AI research assistant, for reading any lengthy research paper and getting a more summarized context of it. A hypothesis can be formed after evaluating many such summarized research papers. Copilot also offers explanations for theories and equations, explains paper in simplified version, allows you to highlight any text in the paper or clip math equations and tables and provides a deeper, clear understanding of what is being said. This can improve the hypothesis by helping you identify potential research gaps.

3. Create a 3-dimensional hypothesis

Variables are an essential part of any reasonable hypothesis. So, identify your independent and dependent variable(s) and form a correlation between them. The ideal way to do this is to write the hypothetical assumption in the ‘if-then' form. If you use this form, make sure that you state the predefined relationship between the variables.

In another way, you can choose to present your hypothesis as a comparison between two variables. Here, you must specify the difference you expect to observe in the results.

4. Write the first draft

Now that everything is in place, it's time to write your hypothesis. For starters, create the first draft. In this version, write what you expect to find from your research.

Clearly separate your independent and dependent variables and the link between them. Don't fixate on syntax at this stage. The goal is to ensure your hypothesis addresses the issue.

5. Proof your hypothesis

After preparing the first draft of your hypothesis, you need to inspect it thoroughly. It should tick all the boxes, like being concise, straightforward, relevant, and accurate. Your final hypothesis has to be well-structured as well.

Research projects are an exciting and crucial part of being a scholar. And once you have your research question, you need a great hypothesis to begin conducting research. Thus, knowing how to write a hypothesis is very important.

Now that you have a firmer grasp on what a good hypothesis constitutes, the different kinds there are, and what process to follow, you will find it much easier to write your hypothesis, which ultimately helps your research.

Now it's easier than ever to streamline your research workflow with SciSpace Discover . Its integrated, comprehensive end-to-end platform for research allows scholars to easily discover, write and publish their research and fosters collaboration.

It includes everything you need, including a repository of over 270 million research papers across disciplines, SEO-optimized summaries and public profiles to show your expertise and experience.

If you found these tips on writing a research hypothesis useful, head over to our blog on Statistical Hypothesis Testing to learn about the top researchers, papers, and institutions in this domain.

Frequently Asked Questions (FAQs)

1. what is the definition of hypothesis.

According to the Oxford dictionary, a hypothesis is defined as “An idea or explanation of something that is based on a few known facts, but that has not yet been proved to be true or correct”.

2. What is an example of hypothesis?

The hypothesis is a statement that proposes a relationship between two or more variables. An example: "If we increase the number of new users who join our platform by 25%, then we will see an increase in revenue."

3. What is an example of null hypothesis?

A null hypothesis is a statement that there is no relationship between two variables. The null hypothesis is written as H0. The null hypothesis states that there is no effect. For example, if you're studying whether or not a particular type of exercise increases strength, your null hypothesis will be "there is no difference in strength between people who exercise and people who don't."

4. What are the types of research?

• Fundamental research

• Applied research

• Qualitative research

• Quantitative research

• Mixed research

• Exploratory research

• Longitudinal research

• Cross-sectional research

• Field research

• Laboratory research

• Fixed research

• Flexible research

• Action research

• Policy research

• Classification research

• Comparative research

• Causal research

• Inductive research

• Deductive research

5. How to write a hypothesis?

• Your hypothesis should be able to predict the relationship and outcome.

• Avoid wordiness by keeping it simple and brief.

• Your hypothesis should contain observable and testable outcomes.

• Your hypothesis should be relevant to the research question.

6. What are the 2 types of hypothesis?

• Null hypotheses are used to test the claim that "there is no difference between two groups of data".

• Alternative hypotheses test the claim that "there is a difference between two data groups".

7. Difference between research question and research hypothesis?

A research question is a broad, open-ended question you will try to answer through your research. A hypothesis is a statement based on prior research or theory that you expect to be true due to your study. Example - Research question: What are the factors that influence the adoption of the new technology? Research hypothesis: There is a positive relationship between age, education and income level with the adoption of the new technology.

8. What is plural for hypothesis?

The plural of hypothesis is hypotheses. Here's an example of how it would be used in a statement, "Numerous well-considered hypotheses are presented in this part, and they are supported by tables and figures that are well-illustrated."

9. What is the red queen hypothesis?

The red queen hypothesis in evolutionary biology states that species must constantly evolve to avoid extinction because if they don't, they will be outcompeted by other species that are evolving. Leigh Van Valen first proposed it in 1973; since then, it has been tested and substantiated many times.

10. Who is known as the father of null hypothesis?

The father of the null hypothesis is Sir Ronald Fisher. He published a paper in 1925 that introduced the concept of null hypothesis testing, and he was also the first to use the term itself.

11. When to reject null hypothesis?

You need to find a significant difference between your two populations to reject the null hypothesis. You can determine that by running statistical tests such as an independent sample t-test or a dependent sample t-test. You should reject the null hypothesis if the p-value is less than 0.05.

example of hypothesis in a comparative study

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Research Questions & Hypotheses

Generally, in quantitative studies, reviewers expect hypotheses rather than research questions. However, both research questions and hypotheses serve different purposes and can be beneficial when used together.

Research Questions

Clarify the research’s aim (farrugia et al., 2010).

  • Research often begins with an interest in a topic, but a deep understanding of the subject is crucial to formulate an appropriate research question.
  • Descriptive: “What factors most influence the academic achievement of senior high school students?”
  • Comparative: “What is the performance difference between teaching methods A and B?”
  • Relationship-based: “What is the relationship between self-efficacy and academic achievement?”
  • Increasing knowledge about a subject can be achieved through systematic literature reviews, in-depth interviews with patients (and proxies), focus groups, and consultations with field experts.
  • Some funding bodies, like the Canadian Institute for Health Research, recommend conducting a systematic review or a pilot study before seeking grants for full trials.
  • The presence of multiple research questions in a study can complicate the design, statistical analysis, and feasibility.
  • It’s advisable to focus on a single primary research question for the study.
  • The primary question, clearly stated at the end of a grant proposal’s introduction, usually specifies the study population, intervention, and other relevant factors.
  • The FINER criteria underscore aspects that can enhance the chances of a successful research project, including specifying the population of interest, aligning with scientific and public interest, clinical relevance, and contribution to the field, while complying with ethical and national research standards.
Feasible
Interesting
Novel
Ethical
Relevant
  • The P ICOT approach is crucial in developing the study’s framework and protocol, influencing inclusion and exclusion criteria and identifying patient groups for inclusion.
Population (patients)
Intervention (for intervention studies only)
Comparison group
Outcome of interest
Time
  • Defining the specific population, intervention, comparator, and outcome helps in selecting the right outcome measurement tool.
  • The more precise the population definition and stricter the inclusion and exclusion criteria, the more significant the impact on the interpretation, applicability, and generalizability of the research findings.
  • A restricted study population enhances internal validity but may limit the study’s external validity and generalizability to clinical practice.
  • A broadly defined study population may better reflect clinical practice but could increase bias and reduce internal validity.
  • An inadequately formulated research question can negatively impact study design, potentially leading to ineffective outcomes and affecting publication prospects.

Checklist: Good research questions for social science projects (Panke, 2018)

example of hypothesis in a comparative study

Research Hypotheses

Present the researcher’s predictions based on specific statements.

  • These statements define the research problem or issue and indicate the direction of the researcher’s predictions.
  • Formulating the research question and hypothesis from existing data (e.g., a database) can lead to multiple statistical comparisons and potentially spurious findings due to chance.
  • The research or clinical hypothesis, derived from the research question, shapes the study’s key elements: sampling strategy, intervention, comparison, and outcome variables.
  • Hypotheses can express a single outcome or multiple outcomes.
  • After statistical testing, the null hypothesis is either rejected or not rejected based on whether the study’s findings are statistically significant.
  • Hypothesis testing helps determine if observed findings are due to true differences and not chance.
  • Hypotheses can be 1-sided (specific direction of difference) or 2-sided (presence of a difference without specifying direction).
  • 2-sided hypotheses are generally preferred unless there’s a strong justification for a 1-sided hypothesis.
  • A solid research hypothesis, informed by a good research question, influences the research design and paves the way for defining clear research objectives.

Types of Research Hypothesis

  • In a Y-centered research design, the focus is on the dependent variable (DV) which is specified in the research question. Theories are then used to identify independent variables (IV) and explain their causal relationship with the DV.
  • Example: “An increase in teacher-led instructional time (IV) is likely to improve student reading comprehension scores (DV), because extensive guided practice under expert supervision enhances learning retention and skill mastery.”
  • Hypothesis Explanation: The dependent variable (student reading comprehension scores) is the focus, and the hypothesis explores how changes in the independent variable (teacher-led instructional time) affect it.
  • In X-centered research designs, the independent variable is specified in the research question. Theories are used to determine potential dependent variables and the causal mechanisms at play.
  • Example: “Implementing technology-based learning tools (IV) is likely to enhance student engagement in the classroom (DV), because interactive and multimedia content increases student interest and participation.”
  • Hypothesis Explanation: The independent variable (technology-based learning tools) is the focus, with the hypothesis exploring its impact on a potential dependent variable (student engagement).
  • Probabilistic hypotheses suggest that changes in the independent variable are likely to lead to changes in the dependent variable in a predictable manner, but not with absolute certainty.
  • Example: “The more teachers engage in professional development programs (IV), the more their teaching effectiveness (DV) is likely to improve, because continuous training updates pedagogical skills and knowledge.”
  • Hypothesis Explanation: This hypothesis implies a probable relationship between the extent of professional development (IV) and teaching effectiveness (DV).
  • Deterministic hypotheses state that a specific change in the independent variable will lead to a specific change in the dependent variable, implying a more direct and certain relationship.
  • Example: “If the school curriculum changes from traditional lecture-based methods to project-based learning (IV), then student collaboration skills (DV) are expected to improve because project-based learning inherently requires teamwork and peer interaction.”
  • Hypothesis Explanation: This hypothesis presumes a direct and definite outcome (improvement in collaboration skills) resulting from a specific change in the teaching method.
  • Example : “Students who identify as visual learners will score higher on tests that are presented in a visually rich format compared to tests presented in a text-only format.”
  • Explanation : This hypothesis aims to describe the potential difference in test scores between visual learners taking visually rich tests and text-only tests, without implying a direct cause-and-effect relationship.
  • Example : “Teaching method A will improve student performance more than method B.”
  • Explanation : This hypothesis compares the effectiveness of two different teaching methods, suggesting that one will lead to better student performance than the other. It implies a direct comparison but does not necessarily establish a causal mechanism.
  • Example : “Students with higher self-efficacy will show higher levels of academic achievement.”
  • Explanation : This hypothesis predicts a relationship between the variable of self-efficacy and academic achievement. Unlike a causal hypothesis, it does not necessarily suggest that one variable causes changes in the other, but rather that they are related in some way.

Tips for developing research questions and hypotheses for research studies

  • Perform a systematic literature review (if one has not been done) to increase knowledge and familiarity with the topic and to assist with research development.
  • Learn about current trends and technological advances on the topic.
  • Seek careful input from experts, mentors, colleagues, and collaborators to refine your research question as this will aid in developing the research question and guide the research study.
  • Use the FINER criteria in the development of the research question.
  • Ensure that the research question follows PICOT format.
  • Develop a research hypothesis from the research question.
  • Ensure that the research question and objectives are answerable, feasible, and clinically relevant.

If your research hypotheses are derived from your research questions, particularly when multiple hypotheses address a single question, it’s recommended to use both research questions and hypotheses. However, if this isn’t the case, using hypotheses over research questions is advised. It’s important to note these are general guidelines, not strict rules. If you opt not to use hypotheses, consult with your supervisor for the best approach.

Farrugia, P., Petrisor, B. A., Farrokhyar, F., & Bhandari, M. (2010). Practical tips for surgical research: Research questions, hypotheses and objectives.  Canadian journal of surgery. Journal canadien de chirurgie ,  53 (4), 278–281.

Hulley, S. B., Cummings, S. R., Browner, W. S., Grady, D., & Newman, T. B. (2007). Designing clinical research. Philadelphia.

Panke, D. (2018). Research design & method selection: Making good choices in the social sciences.  Research Design & Method Selection , 1-368.

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How to Write a Strong Hypothesis | Guide & Examples

Published on 6 May 2022 by Shona McCombes .

A hypothesis is a statement that can be tested by scientific research. If you want to test a relationship between two or more variables, you need to write hypotheses before you start your experiment or data collection.

Table of contents

What is a hypothesis, developing a hypothesis (with example), hypothesis examples, frequently asked questions about writing hypotheses.

A hypothesis states your predictions about what your research will find. It is a tentative answer to your research question that has not yet been tested. For some research projects, you might have to write several hypotheses that address different aspects of your research question.

A hypothesis is not just a guess – it should be based on existing theories and knowledge. It also has to be testable, which means you can support or refute it through scientific research methods (such as experiments, observations, and statistical analysis of data).

Variables in hypotheses

Hypotheses propose a relationship between two or more variables . An independent variable is something the researcher changes or controls. A dependent variable is something the researcher observes and measures.

In this example, the independent variable is exposure to the sun – the assumed cause . The dependent variable is the level of happiness – the assumed effect .

Prevent plagiarism, run a free check.

Step 1: ask a question.

Writing a hypothesis begins with a research question that you want to answer. The question should be focused, specific, and researchable within the constraints of your project.

Step 2: Do some preliminary research

Your initial answer to the question should be based on what is already known about the topic. Look for theories and previous studies to help you form educated assumptions about what your research will find.

At this stage, you might construct a conceptual framework to identify which variables you will study and what you think the relationships are between them. Sometimes, you’ll have to operationalise more complex constructs.

Step 3: Formulate your hypothesis

Now you should have some idea of what you expect to find. Write your initial answer to the question in a clear, concise sentence.

Step 4: Refine your hypothesis

You need to make sure your hypothesis is specific and testable. There are various ways of phrasing a hypothesis, but all the terms you use should have clear definitions, and the hypothesis should contain:

  • The relevant variables
  • The specific group being studied
  • The predicted outcome of the experiment or analysis

Step 5: Phrase your hypothesis in three ways

To identify the variables, you can write a simple prediction in if … then form. The first part of the sentence states the independent variable and the second part states the dependent variable.

In academic research, hypotheses are more commonly phrased in terms of correlations or effects, where you directly state the predicted relationship between variables.

If you are comparing two groups, the hypothesis can state what difference you expect to find between them.

Step 6. Write a null hypothesis

If your research involves statistical hypothesis testing , you will also have to write a null hypothesis. The null hypothesis is the default position that there is no association between the variables. The null hypothesis is written as H 0 , while the alternative hypothesis is H 1 or H a .

Research question Hypothesis Null hypothesis
What are the health benefits of eating an apple a day? Increasing apple consumption in over-60s will result in decreasing frequency of doctor’s visits. Increasing apple consumption in over-60s will have no effect on frequency of doctor’s visits.
Which airlines have the most delays? Low-cost airlines are more likely to have delays than premium airlines. Low-cost and premium airlines are equally likely to have delays.
Can flexible work arrangements improve job satisfaction? Employees who have flexible working hours will report greater job satisfaction than employees who work fixed hours. There is no relationship between working hour flexibility and job satisfaction.
How effective is secondary school sex education at reducing teen pregnancies? Teenagers who received sex education lessons throughout secondary school will have lower rates of unplanned pregnancy than teenagers who did not receive any sex education. Secondary school sex education has no effect on teen pregnancy rates.
What effect does daily use of social media have on the attention span of under-16s? There is a negative correlation between time spent on social media and attention span in under-16s. There is no relationship between social media use and attention span in under-16s.

Hypothesis testing is a formal procedure for investigating our ideas about the world using statistics. It is used by scientists to test specific predictions, called hypotheses , by calculating how likely it is that a pattern or relationship between variables could have arisen by chance.

A hypothesis is not just a guess. It should be based on existing theories and knowledge. It also has to be testable, which means you can support or refute it through scientific research methods (such as experiments, observations, and statistical analysis of data).

A research hypothesis is your proposed answer to your research question. The research hypothesis usually includes an explanation (‘ x affects y because …’).

A statistical hypothesis, on the other hand, is a mathematical statement about a population parameter. Statistical hypotheses always come in pairs: the null and alternative hypotheses. In a well-designed study , the statistical hypotheses correspond logically to the research hypothesis.

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10.1 - setting the hypotheses: examples.

A significance test examines whether the null hypothesis provides a plausible explanation of the data. The null hypothesis itself does not involve the data. It is a statement about a parameter (a numerical characteristic of the population). These population values might be proportions or means or differences between means or proportions or correlations or odds ratios or any other numerical summary of the population. The alternative hypothesis is typically the research hypothesis of interest. Here are some examples.

Example 10.2: Hypotheses with One Sample of One Categorical Variable Section  

About 10% of the human population is left-handed. Suppose a researcher at Penn State speculates that students in the College of Arts and Architecture are more likely to be left-handed than people found in the general population. We only have one sample since we will be comparing a population proportion based on a sample value to a known population value.

  • Research Question : Are artists more likely to be left-handed than people found in the general population?
  • Response Variable : Classification of the student as either right-handed or left-handed

State Null and Alternative Hypotheses

  • Null Hypothesis : Students in the College of Arts and Architecture are no more likely to be left-handed than people in the general population (population percent of left-handed students in the College of Art and Architecture = 10% or p = .10).
  • Alternative Hypothesis : Students in the College of Arts and Architecture are more likely to be left-handed than people in the general population (population percent of left-handed students in the College of Arts and Architecture > 10% or p > .10). This is a one-sided alternative hypothesis.

Example 10.3: Hypotheses with One Sample of One Measurement Variable Section  

 two Diphenhydramine pills

A generic brand of the anti-histamine Diphenhydramine markets a capsule with a 50 milligram dose. The manufacturer is worried that the machine that fills the capsules has come out of calibration and is no longer creating capsules with the appropriate dosage.

  • Research Question : Does the data suggest that the population mean dosage of this brand is different than 50 mg?
  • Response Variable : dosage of the active ingredient found by a chemical assay.
  • Null Hypothesis : On the average, the dosage sold under this brand is 50 mg (population mean dosage = 50 mg).
  • Alternative Hypothesis : On the average, the dosage sold under this brand is not 50 mg (population mean dosage ≠ 50 mg). This is a two-sided alternative hypothesis.

Example 10.4: Hypotheses with Two Samples of One Categorical Variable Section  

vegetarian airline meal

Many people are starting to prefer vegetarian meals on a regular basis. Specifically, a researcher believes that females are more likely than males to eat vegetarian meals on a regular basis.

  • Research Question : Does the data suggest that females are more likely than males to eat vegetarian meals on a regular basis?
  • Response Variable : Classification of whether or not a person eats vegetarian meals on a regular basis
  • Explanatory (Grouping) Variable: Sex
  • Null Hypothesis : There is no sex effect regarding those who eat vegetarian meals on a regular basis (population percent of females who eat vegetarian meals on a regular basis = population percent of males who eat vegetarian meals on a regular basis or p females = p males ).
  • Alternative Hypothesis : Females are more likely than males to eat vegetarian meals on a regular basis (population percent of females who eat vegetarian meals on a regular basis > population percent of males who eat vegetarian meals on a regular basis or p females > p males ). This is a one-sided alternative hypothesis.

Example 10.5: Hypotheses with Two Samples of One Measurement Variable Section  

low carb meal

Obesity is a major health problem today. Research is starting to show that people may be able to lose more weight on a low carbohydrate diet than on a low fat diet.

  • Research Question : Does the data suggest that, on the average, people are able to lose more weight on a low carbohydrate diet than on a low fat diet?
  • Response Variable : Weight loss (pounds)
  • Explanatory (Grouping) Variable : Type of diet
  • Null Hypothesis : There is no difference in the mean amount of weight loss when comparing a low carbohydrate diet with a low fat diet (population mean weight loss on a low carbohydrate diet = population mean weight loss on a low fat diet).
  • Alternative Hypothesis : The mean weight loss should be greater for those on a low carbohydrate diet when compared with those on a low fat diet (population mean weight loss on a low carbohydrate diet > population mean weight loss on a low fat diet). This is a one-sided alternative hypothesis.

Example 10.6: Hypotheses about the relationship between Two Categorical Variables Section  

  • Research Question : Do the odds of having a stroke increase if you inhale second hand smoke ? A case-control study of non-smoking stroke patients and controls of the same age and occupation are asked if someone in their household smokes.
  • Variables : There are two different categorical variables (Stroke patient vs control and whether the subject lives in the same household as a smoker). Living with a smoker (or not) is the natural explanatory variable and having a stroke (or not) is the natural response variable in this situation.
  • Null Hypothesis : There is no relationship between whether or not a person has a stroke and whether or not a person lives with a smoker (odds ratio between stroke and second-hand smoke situation is = 1).
  • Alternative Hypothesis : There is a relationship between whether or not a person has a stroke and whether or not a person lives with a smoker (odds ratio between stroke and second-hand smoke situation is > 1). This is a one-tailed alternative.

This research question might also be addressed like example 11.4 by making the hypotheses about comparing the proportion of stroke patients that live with smokers to the proportion of controls that live with smokers.

Example 10.7: Hypotheses about the relationship between Two Measurement Variables Section  

  • Research Question : A financial analyst believes there might be a positive association between the change in a stock's price and the amount of the stock purchased by non-management employees the previous day (stock trading by management being under "insider-trading" regulatory restrictions).
  • Variables : Daily price change information (the response variable) and previous day stock purchases by non-management employees (explanatory variable). These are two different measurement variables.
  • Null Hypothesis : The correlation between the daily stock price change (\$) and the daily stock purchases by non-management employees (\$) = 0.
  • Alternative Hypothesis : The correlation between the daily stock price change (\$) and the daily stock purchases by non-management employees (\$) > 0. This is a one-sided alternative hypothesis.

Example 10.8: Hypotheses about comparing the relationship between Two Measurement Variables in Two Samples Section  

Calculation of a person's approximate tip for their meal

  • Research Question : Is there a linear relationship between the amount of the bill (\$) at a restaurant and the tip (\$) that was left. Is the strength of this association different for family restaurants than for fine dining restaurants?
  • Variables : There are two different measurement variables. The size of the tip would depend on the size of the bill so the amount of the bill would be the explanatory variable and the size of the tip would be the response variable.
  • Null Hypothesis : The correlation between the amount of the bill (\$) at a restaurant and the tip (\$) that was left is the same at family restaurants as it is at fine dining restaurants.
  • Alternative Hypothesis : The correlation between the amount of the bill (\$) at a restaurant and the tip (\$) that was left is the difference at family restaurants then it is at fine dining restaurants. This is a two-sided alternative hypothesis.

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B oth the hypothesis statement and the thesis statement answer the research question of the study.  When the statement is one that can be proved or disproved, it is an hypothesis statement.  If, instead, the statement specifically shows the intentions/objectives/position of the researcher, it is a thesis statement.

A hypothesis is a statement that can be proved or disproved.  It is typically used in quantitative research and predicts the relationship between variables.

A thesis statement is a short, direct sentence that summarizes the main point or claim of an essay or research paper. It is seen in quantitative, qualitative, and mixed methods research.  A thesis statement is developed, supported, and explained in the body of the essay or research report by means of examples and evidence.

Every research study should contain a concise and well-written thesis statement. If the intent of the study is to prove/disprove something, that research report will also contain an hypothesis statement.

Jablonski , Judith. What is the difference between a thesis statement and an hypothesis statement? Online Library. American Public University System. Jun 16, 2014. Web.   http://apus.libanswers.com/faq/2374

Let’s say you are interested in the conflict in Darfur, and you conclude that the issues you wish to address include the nature, causes, and effects of the conflict, and the international response. While you could address the issue of international response first, it makes the most sense to start with a description of the conflict, followed by an exploration of the causes, effects, and then to discuss the international response and what more could/should be done.

This hypothetical example may lead to the following title, introduction, and statement of questions:

Conflict in Darfur: Causes, Consequences, and International Response       This paper examines the conflict in Darfur, Sudan. It is organized around the following questions: (1) What is the nature of the conflict in Darfur? (2) What are the causes and effects of the conflict? (3) What has the international community done to address it, and what more could/should it do?

Following the section that presents your questions and background, you will offer a set of responses/answers/(hypo)theses. They should follow the order of the questions. This might look something like this, “The paper argues/contends/ maintains/seeks to develop the position that...etc.” The most important thing you can do in this section is to present as clearly as possible your best thinking on the subject matter guided by course material and research. As you proceed through the research process, your thinking about the issues/questions will become more nuanced, complex, and refined. The statement of your theses will reflect this as you move forward in the research process.

So, looking to our hypothetical example on Darfur:

The current conflict in Darfur goes back more than a decade and consists of fighting between government-supported troops and residents of Darfur. The causes of the conflict include x, y, and z. The effects of the conflict have been a, b, and c. The international community has done 0, and it should do 1, 2, and 3.

Once you have setup your thesis you will be ready to begin amassing supporting evidence for you claims. This is a very important part of the research paper, as you will provide the substance to defend your thesis.

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Lau F, Kuziemsky C, editors. Handbook of eHealth Evaluation: An Evidence-based Approach [Internet]. Victoria (BC): University of Victoria; 2017 Feb 27.

Cover of Handbook of eHealth Evaluation: An Evidence-based Approach

Handbook of eHealth Evaluation: An Evidence-based Approach [Internet].

Chapter 10 methods for comparative studies.

Francis Lau and Anne Holbrook .

10.1. Introduction

In eHealth evaluation, comparative studies aim to find out whether group differences in eHealth system adoption make a difference in important outcomes. These groups may differ in their composition, the type of system in use, and the setting where they work over a given time duration. The comparisons are to determine whether significant differences exist for some predefined measures between these groups, while controlling for as many of the conditions as possible such as the composition, system, setting and duration.

According to the typology by Friedman and Wyatt (2006) , comparative studies take on an objective view where events such as the use and effect of an eHealth system can be defined, measured and compared through a set of variables to prove or disprove a hypothesis. For comparative studies, the design options are experimental versus observational and prospective versus retro­­spective. The quality of eHealth comparative studies depends on such aspects of methodological design as the choice of variables, sample size, sources of bias, confounders, and adherence to quality and reporting guidelines.

In this chapter we focus on experimental studies as one type of comparative study and their methodological considerations that have been reported in the eHealth literature. Also included are three case examples to show how these studies are done.

10.2. Types of Comparative Studies

Experimental studies are one type of comparative study where a sample of participants is identified and assigned to different conditions for a given time duration, then compared for differences. An example is a hospital with two care units where one is assigned a cpoe system to process medication orders electronically while the other continues its usual practice without a cpoe . The participants in the unit assigned to the cpoe are called the intervention group and those assigned to usual practice are the control group. The comparison can be performance or outcome focused, such as the ratio of correct orders processed or the occurrence of adverse drug events in the two groups during the given time period. Experimental studies can take on a randomized or non-randomized design. These are described below.

10.2.1. Randomized Experiments

In a randomized design, the participants are randomly assigned to two or more groups using a known randomization technique such as a random number table. The design is prospective in nature since the groups are assigned concurrently, after which the intervention is applied then measured and compared. Three types of experimental designs seen in eHealth evaluation are described below ( Friedman & Wyatt, 2006 ; Zwarenstein & Treweek, 2009 ).

Randomized controlled trials ( rct s) – In rct s participants are randomly assigned to an intervention or a control group. The randomization can occur at the patient, provider or organization level, which is known as the unit of allocation. For instance, at the patient level one can randomly assign half of the patients to receive emr reminders while the other half do not. At the provider level, one can assign half of the providers to receive the reminders while the other half continues with their usual practice. At the organization level, such as a multisite hospital, one can randomly assign emr reminders to some of the sites but not others. Cluster randomized controlled trials ( crct s) – In crct s, clusters of participants are randomized rather than by individual participant since they are found in naturally occurring groups such as living in the same communities. For instance, clinics in one city may be randomized as a cluster to receive emr reminders while clinics in another city continue their usual practice. Pragmatic trials – Unlike rct s that seek to find out if an intervention such as a cpoe system works under ideal conditions, pragmatic trials are designed to find out if the intervention works under usual conditions. The goal is to make the design and findings relevant to and practical for decision-makers to apply in usual settings. As such, pragmatic trials have few criteria for selecting study participants, flexibility in implementing the intervention, usual practice as the comparator, the same compliance and follow-up intensity as usual practice, and outcomes that are relevant to decision-makers.

10.2.2. Non-randomized Experiments

Non-randomized design is used when it is neither feasible nor ethical to randomize participants into groups for comparison. It is sometimes referred to as a quasi-experimental design. The design can involve the use of prospective or retrospective data from the same or different participants as the control group. Three types of non-randomized designs are described below ( Harris et al., 2006 ).

Intervention group only with pretest and post-test design – This design involves only one group where a pretest or baseline measure is taken as the control period, the intervention is implemented, and a post-test measure is taken as the intervention period for comparison. For example, one can compare the rates of medication errors before and after the implementation of a cpoe system in a hospital. To increase study quality, one can add a second pretest period to decrease the probability that the pretest and post-test difference is due to chance, such as an unusually low medication error rate in the first pretest period. Other ways to increase study quality include adding an unrelated outcome such as patient case-mix that should not be affected, removing the intervention to see if the difference remains, and removing then re-implementing the intervention to see if the differences vary accordingly. Intervention and control groups with post-test design – This design involves two groups where the intervention is implemented in one group and compared with a second group without the intervention, based on a post-test measure from both groups. For example, one can implement a cpoe system in one care unit as the intervention group with a second unit as the control group and compare the post-test medication error rates in both units over six months. To increase study quality, one can add one or more pretest periods to both groups, or implement the intervention to the control group at a later time to measure for similar but delayed effects. Interrupted time series ( its ) design – In its design, multiple measures are taken from one group in equal time intervals, interrupted by the implementation of the intervention. The multiple pretest and post-test measures decrease the probability that the differences detected are due to chance or unrelated effects. An example is to take six consecutive monthly medication error rates as the pretest measures, implement the cpoe system, then take another six consecutive monthly medication error rates as the post-test measures for comparison in error rate differences over 12 months. To increase study quality, one may add a concurrent control group for comparison to be more convinced that the intervention produced the change.

10.3. Methodological Considerations

The quality of comparative studies is dependent on their internal and external validity. Internal validity refers to the extent to which conclusions can be drawn correctly from the study setting, participants, intervention, measures, analysis and interpretations. External validity refers to the extent to which the conclusions can be generalized to other settings. The major factors that influence validity are described below.

10.3.1. Choice of Variables

Variables are specific measurable features that can influence validity. In comparative studies, the choice of dependent and independent variables and whether they are categorical and/or continuous in values can affect the type of questions, study design and analysis to be considered. These are described below ( Friedman & Wyatt, 2006 ).

Dependent variables – This refers to outcomes of interest; they are also known as outcome variables. An example is the rate of medication errors as an outcome in determining whether cpoe can improve patient safety. Independent variables – This refers to variables that can explain the measured values of the dependent variables. For instance, the characteristics of the setting, participants and intervention can influence the effects of cpoe . Categorical variables – This refers to variables with measured values in discrete categories or levels. Examples are the type of providers (e.g., nurses, physicians and pharmacists), the presence or absence of a disease, and pain scale (e.g., 0 to 10 in increments of 1). Categorical variables are analyzed using non-parametric methods such as chi-square and odds ratio. Continuous variables – This refers to variables that can take on infinite values within an interval limited only by the desired precision. Examples are blood pressure, heart rate and body temperature. Continuous variables are analyzed using parametric methods such as t -test, analysis of variance or multiple regression.

10.3.2. Sample Size

Sample size is the number of participants to include in a study. It can refer to patients, providers or organizations depending on how the unit of allocation is defined. There are four parts to calculating sample size. They are described below ( Noordzij et al., 2010 ).

Significance level – This refers to the probability that a positive finding is due to chance alone. It is usually set at 0.05, which means having a less than 5% chance of drawing a false positive conclusion. Power – This refers to the ability to detect the true effect based on a sample from the population. It is usually set at 0.8, which means having at least an 80% chance of drawing a correct conclusion. Effect size – This refers to the minimal clinically relevant difference that can be detected between comparison groups. For continuous variables, the effect is a numerical value such as a 10-kilogram weight difference between two groups. For categorical variables, it is a percentage such as a 10% difference in medication error rates. Variability – This refers to the population variance of the outcome of interest, which is often unknown and is estimated by way of standard deviation ( sd ) from pilot or previous studies for continuous outcome.

Table 10.1. Sample Size Equations for Comparing Two Groups with Continuous and Categorical Outcome Variables.

Sample Size Equations for Comparing Two Groups with Continuous and Categorical Outcome Variables.

An example of sample size calculation for an rct to examine the effect of cds on improving systolic blood pressure of hypertensive patients is provided in the Appendix. Refer to the Biomath website from Columbia University (n.d.) for a simple Web-based sample size / power calculator.

10.3.3. Sources of Bias

There are five common sources of biases in comparative studies. They are selection, performance, detection, attrition and reporting biases ( Higgins & Green, 2011 ). These biases, and the ways to minimize them, are described below ( Vervloet et al., 2012 ).

Selection or allocation bias – This refers to differences between the composition of comparison groups in terms of the response to the intervention. An example is having sicker or older patients in the control group than those in the intervention group when evaluating the effect of emr reminders. To reduce selection bias, one can apply randomization and concealment when assigning participants to groups and ensure their compositions are comparable at baseline. Performance bias – This refers to differences between groups in the care they received, aside from the intervention being evaluated. An example is the different ways by which reminders are triggered and used within and across groups such as electronic, paper and phone reminders for patients and providers. To reduce performance bias, one may standardize the intervention and blind participants from knowing whether an intervention was received and which intervention was received. Detection or measurement bias – This refers to differences between groups in how outcomes are determined. An example is where outcome assessors pay more attention to outcomes of patients known to be in the intervention group. To reduce detection bias, one may blind assessors from participants when measuring outcomes and ensure the same timing for assessment across groups. Attrition bias – This refers to differences between groups in ways that participants are withdrawn from the study. An example is the low rate of participant response in the intervention group despite having received reminders for follow-up care. To reduce attrition bias, one needs to acknowledge the dropout rate and analyze data according to an intent-to-treat principle (i.e., include data from those who dropped out in the analysis). Reporting bias – This refers to differences between reported and unreported findings. Examples include biases in publication, time lag, citation, language and outcome reporting depending on the nature and direction of the results. To reduce reporting bias, one may make the study protocol available with all pre-specified outcomes and report all expected outcomes in published results.

10.3.4. Confounders

Confounders are factors other than the intervention of interest that can distort the effect because they are associated with both the intervention and the outcome. For instance, in a study to demonstrate whether the adoption of a medication order entry system led to lower medication costs, there can be a number of potential confounders that can affect the outcome. These may include severity of illness of the patients, provider knowledge and experience with the system, and hospital policy on prescribing medications ( Harris et al., 2006 ). Another example is the evaluation of the effect of an antibiotic reminder system on the rate of post-operative deep venous thromboses ( dvt s). The confounders can be general improvements in clinical practice during the study such as prescribing patterns and post-operative care that are not related to the reminders ( Friedman & Wyatt, 2006 ).

To control for confounding effects, one may consider the use of matching, stratification and modelling. Matching involves the selection of similar groups with respect to their composition and behaviours. Stratification involves the division of participants into subgroups by selected variables, such as comorbidity index to control for severity of illness. Modelling involves the use of statistical techniques such as multiple regression to adjust for the effects of specific variables such as age, sex and/or severity of illness ( Higgins & Green, 2011 ).

10.3.5. Guidelines on Quality and Reporting

There are guidelines on the quality and reporting of comparative studies. The grade (Grading of Recommendations Assessment, Development and Evaluation) guidelines provide explicit criteria for rating the quality of studies in randomized trials and observational studies ( Guyatt et al., 2011 ). The extended consort (Consolidated Standards of Reporting Trials) Statements for non-pharmacologic trials ( Boutron, Moher, Altman, Schulz, & Ravaud, 2008 ), pragmatic trials ( Zwarestein et al., 2008 ), and eHealth interventions ( Baker et al., 2010 ) provide reporting guidelines for randomized trials.

The grade guidelines offer a system of rating quality of evidence in systematic reviews and guidelines. In this approach, to support estimates of intervention effects rct s start as high-quality evidence and observational studies as low-quality evidence. For each outcome in a study, five factors may rate down the quality of evidence. The final quality of evidence for each outcome would fall into one of high, moderate, low, and very low quality. These factors are listed below (for more details on the rating system, refer to Guyatt et al., 2011 ).

Design limitations – For rct s they cover the lack of allocation concealment, lack of blinding, large loss to follow-up, trial stopped early or selective outcome reporting. Inconsistency of results – Variations in outcomes due to unexplained heterogeneity. An example is the unexpected variation of effects across subgroups of patients by severity of illness in the use of preventive care reminders. Indirectness of evidence – Reliance on indirect comparisons due to restrictions in study populations, intervention, comparator or outcomes. An example is the 30-day readmission rate as a surrogate outcome for quality of computer-supported emergency care in hospitals. Imprecision of results – Studies with small sample size and few events typically would have wide confidence intervals and are considered of low quality. Publication bias – The selective reporting of results at the individual study level is already covered under design limitations, but is included here for completeness as it is relevant when rating quality of evidence across studies in systematic reviews.

The original consort Statement has 22 checklist items for reporting rct s. For non-pharmacologic trials extensions have been made to 11 items. For pragmatic trials extensions have been made to eight items. These items are listed below. For further details, readers can refer to Boutron and colleagues (2008) and the consort website ( consort , n.d.).

Title and abstract – one item on the means of randomization used. Introduction – one item on background, rationale, and problem addressed by the intervention. Methods – 10 items on participants, interventions, objectives, outcomes, sample size, randomization (sequence generation, allocation concealment, implementation), blinding (masking), and statistical methods. Results – seven items on participant flow, recruitment, baseline data, numbers analyzed, outcomes and estimation, ancillary analyses, adverse events. Discussion – three items on interpretation, generalizability, overall evidence.

The consort Statement for eHealth interventions describes the relevance of the consort recommendations to the design and reporting of eHealth studies with an emphasis on Internet-based interventions for direct use by patients, such as online health information resources, decision aides and phr s. Of particular importance is the need to clearly define the intervention components, their role in the overall care process, target population, implementation process, primary and secondary outcomes, denominators for outcome analyses, and real world potential (for details refer to Baker et al., 2010 ).

10.4. Case Examples

10.4.1. pragmatic rct in vascular risk decision support.

Holbrook and colleagues (2011) conducted a pragmatic rct to examine the effects of a cds intervention on vascular care and outcomes for older adults. The study is summarized below.

Setting – Community-based primary care practices with emr s in one Canadian province. Participants – English-speaking patients 55 years of age or older with diagnosed vascular disease, no cognitive impairment and not living in a nursing home, who had a provider visit in the past 12 months. Intervention – A Web-based individualized vascular tracking and advice cds system for eight top vascular risk factors and two diabetic risk factors, for use by both providers and patients and their families. Providers and staff could update the patient’s profile at any time and the cds algorithm ran nightly to update recommendations and colour highlighting used in the tracker interface. Intervention patients had Web access to the tracker, a print version mailed to them prior to the visit, and telephone support on advice. Design – Pragmatic, one-year, two-arm, multicentre rct , with randomization upon patient consent by phone, using an allocation-concealed online program. Randomization was by patient with stratification by provider using a block size of six. Trained reviewers examined emr data and conducted patient telephone interviews to collect risk factors, vascular history, and vascular events. Providers completed questionnaires on the intervention at study end. Patients had final 12-month lab checks on urine albumin, low-density lipoprotein cholesterol, and A1c levels. Outcomes – Primary outcome was based on change in process composite score ( pcs ) computed as the sum of frequency-weighted process score for each of the eight main risk factors with a maximum score of 27. The process was considered met if a risk factor had been checked. pcs was measured at baseline and study end with the difference as the individual primary outcome scores. The main secondary outcome was a clinical composite score ( ccs ) based on the same eight risk factors compared in two ways: a comparison of the mean number of clinical variables on target and the percentage of patients with improvement between the two groups. Other secondary outcomes were actual vascular event rates, individual pcs and ccs components, ratings of usability, continuity of care, patient ability to manage vascular risk, and quality of life using the EuroQol five dimensions questionnaire ( eq-5D) . Analysis – 1,100 patients were needed to achieve 90% power in detecting a one-point pcs difference between groups with a standard deviation of five points, two-tailed t -test for mean difference at 5% significance level, and a withdrawal rate of 10%. The pcs , ccs and eq-5D scores were analyzed using a generalized estimating equation accounting for clustering within providers. Descriptive statistics and χ2 tests or exact tests were done with other outcomes. Findings – 1,102 patients and 49 providers enrolled in the study. The intervention group with 545 patients had significant pcs improvement with a difference of 4.70 ( p < .001) on a 27-point scale. The intervention group also had significantly higher odds of rating improvements in their continuity of care (4.178, p < .001) and ability to improve their vascular health (3.07, p < .001). There was no significant change in vascular events, clinical variables and quality of life. Overall the cds intervention led to reduced vascular risks but not to improved clinical outcomes in a one-year follow-up.

10.4.2. Non-randomized Experiment in Antibiotic Prescribing in Primary Care

Mainous, Lambourne, and Nietert (2013) conducted a prospective non-randomized trial to examine the impact of a cds system on antibiotic prescribing for acute respiratory infections ( ari s) in primary care. The study is summarized below.

Setting – A primary care research network in the United States whose members use a common emr and pool data quarterly for quality improvement and research studies. Participants – An intervention group with nine practices across nine states, and a control group with 61 practices. Intervention – Point-of-care cds tool as customizable progress note templates based on existing emr features. cds recommendations reflect Centre for Disease Control and Prevention ( cdc ) guidelines based on a patient’s predominant presenting symptoms and age. cds was used to assist in ari diagnosis, prompt antibiotic use, record diagnosis and treatment decisions, and access printable patient and provider education resources from the cdc . Design – The intervention group received a multi-method intervention to facilitate provider cds adoption that included quarterly audit and feedback, best practice dissemination meetings, academic detailing site visits, performance review and cds training. The control group did not receive information on the intervention, the cds or education. Baseline data collection was for three months with follow-up of 15 months after cds implementation. Outcomes – The outcomes were frequency of inappropriate prescribing during an ari episode, broad-spectrum antibiotic use and diagnostic shift. Inappropriate prescribing was computed by dividing the number of ari episodes with diagnoses in the inappropriate category that had an antibiotic prescription by the total number of ari episodes with diagnosis for which antibiotics are inappropriate. Broad-spectrum antibiotic use was computed by all ari episodes with a broad-spectrum antibiotic prescription by the total number of ari episodes with an antibiotic prescription. Antibiotic drift was computed in two ways: dividing the number of ari episodes with diagnoses where antibiotics are appropriate by the total number of ari episodes with an antibiotic prescription; and dividing the number of ari episodes where antibiotics were inappropriate by the total number of ari episodes. Process measure included frequency of cds template use and whether the outcome measures differed by cds usage. Analysis – Outcomes were measured quarterly for each practice, weighted by the number of ari episodes during the quarter to assign greater weight to practices with greater numbers of relevant episodes and to periods with greater numbers of relevant episodes. Weighted means and 95% ci s were computed separately for adult and pediatric (less than 18 years of age) patients for each time period for both groups. Baseline means in outcome measures were compared between the two groups using weighted independent-sample t -tests. Linear mixed models were used to compare changes over the 18-month period. The models included time, intervention status, and were adjusted for practice characteristics such as specialty, size, region and baseline ari s. Random practice effects were included to account for clustering of repeated measures on practices over time. P -values of less than 0.05 were considered significant. Findings – For adult patients, inappropriate prescribing in ari episodes declined more among the intervention group (-0.6%) than the control group (4.2%)( p = 0.03), and prescribing of broad-spectrum antibiotics declined by 16.6% in the intervention group versus an increase of 1.1% in the control group ( p < 0.0001). For pediatric patients, there was a similar decline of 19.7% in the intervention group versus an increase of 0.9% in the control group ( p < 0.0001). In summary, the cds had a modest effect in reducing inappropriate prescribing for adults, but had a substantial effect in reducing the prescribing of broad-spectrum antibiotics in adult and pediatric patients.

10.4.3. Interrupted Time Series on EHR Impact in Nursing Care

Dowding, Turley, and Garrido (2012) conducted a prospective its study to examine the impact of ehr implementation on nursing care processes and outcomes. The study is summarized below.

Setting – Kaiser Permanente ( kp ) as a large not-for-profit integrated healthcare organization in the United States. Participants – 29 kp hospitals in the northern and southern regions of California. Intervention – An integrated ehr system implemented at all hospitals with cpoe , nursing documentation and risk assessment tools. The nursing component for risk assessment documentation of pressure ulcers and falls was consistent across hospitals and developed by clinical nurses and informaticists by consensus. Design – its design with monthly data on pressure ulcers and quarterly data on fall rates and risk collected over seven years between 2003 and 2009. All data were collected at the unit level for each hospital. Outcomes – Process measures were the proportion of patients with a fall risk assessment done and the proportion with a hospital-acquired pressure ulcer ( hapu ) risk assessment done within 24 hours of admission. Outcome measures were fall and hapu rates as part of the unit-level nursing care process and nursing sensitive outcome data collected routinely for all California hospitals. Fall rate was defined as the number of unplanned descents to the floor per 1,000 patient days, and hapu rate was the percentage of patients with stages i-IV or unstageable ulcer on the day of data collection. Analysis – Fall and hapu risk data were synchronized using the month in which the ehr was implemented at each hospital as time zero and aggregated across hospitals for each time period. Multivariate regression analysis was used to examine the effect of time, region and ehr . Findings – The ehr was associated with significant increase in document rates for hapu risk (2.21; 95% CI 0.67 to 3.75) and non-significant increase for fall risk (0.36; -3.58 to 4.30). The ehr was associated with 13% decrease in hapu rates (-0.76; -1.37 to -0.16) but no change in fall rates (-0.091; -0.29 to 011). Hospital region was a significant predictor of variation for hapu (0.72; 0.30 to 1.14) and fall rates (0.57; 0.41 to 0.72). During the study period, hapu rates decreased significantly (-0.16; -0.20 to -0.13) but not fall rates (0.0052; -0.01 to 0.02). In summary, ehr implementation was associated with a reduction in the number of hapu s but not patient falls, and changes over time and hospital region also affected outcomes.

10.5. Summary

In this chapter we introduced randomized and non-randomized experimental designs as two types of comparative studies used in eHealth evaluation. Randomization is the highest quality design as it reduces bias, but it is not always feasible. The methodological issues addressed include choice of variables, sample size, sources of biases, confounders, and adherence to reporting guidelines. Three case examples were included to show how eHealth comparative studies are done.

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  • Holbrook A., Pullenayegum E., Thabane L., Troyan S., Foster G., Keshavjee K. et al. Curnew G. Shared electronic vascular risk decision support in primary care. Computerization of medical practices for the enhancement of therapeutic effectiveness (compete III) randomized trial. Archives of Internal Medicine. 2011; 171 (19):1736–1744. [ PubMed : 22025430 ]
  • Mainous III A. G., Lambourne C. A., Nietert P.J. Impact of a clinical decision support system on antibiotic prescribing for acute respiratory infections in primary care: quasi-experimental trial. Journal of the American Medical Informatics Association. 2013; 20 (2):317–324. [ PMC free article : PMC3638170 ] [ PubMed : 22759620 ]
  • Noordzij M., Tripepi G., Dekker F. W., Zoccali C., Tanck M. W., Jager K.J. Sample size calculations: basic principles and common pitfalls. Nephrology Dialysis Transplantation. 2010; 25 (5):1388–1393. Retrieved from http://ndt ​.oxfordjournals ​.org/content/early/2010/01/12/ndt ​.gfp732.short . [ PubMed : 20067907 ]
  • Vervloet M., Linn A. J., van Weert J. C. M., de Bakker D. H., Bouvy M. L., van Dijk L. The effectiveness of interventions using electronic reminders to improve adherence to chronic medication: A systematic review of the literature. Journal of the American Medical Informatics Association. 2012; 19 (5):696–704. [ PMC free article : PMC3422829 ] [ PubMed : 22534082 ]
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Appendix. Example of Sample Size Calculation

This is an example of sample size calculation for an rct that examines the effect of a cds system on reducing systolic blood pressure in hypertensive patients. The case is adapted from the example described in the publication by Noordzij et al. (2010) .

(a) Systolic blood pressure as a continuous outcome measured in mmHg

Based on similar studies in the literature with similar patients, the systolic blood pressure values from the comparison groups are expected to be normally distributed with a standard deviation of 20 mmHg. The evaluator wishes to detect a clinically relevant difference of 15 mmHg in systolic blood pressure as an outcome between the intervention group with cds and the control group without cds . Assuming a significance level or alpha of 0.05 for 2-tailed t -test and power of 0.80, the corresponding multipliers 1 are 1.96 and 0.842, respectively. Using the sample size equation for continuous outcome below we can calculate the sample size needed for the above study.

n = 2[(a+b)2σ2]/(μ1-μ2)2 where

n = sample size for each group

μ1 = population mean of systolic blood pressures in intervention group

μ2 = population mean of systolic blood pressures in control group

μ1- μ2 = desired difference in mean systolic blood pressures between groups

σ = population variance

a = multiplier for significance level (or alpha)

b = multiplier for power (or 1-beta)

Providing the values in the equation would give the sample size (n) of 28 samples per group as the result

n = 2[(1.96+0.842)2(202)]/152 or 28 samples per group

(b) Systolic blood pressure as a categorical outcome measured as below or above 140 mmHg (i.e., hypertension yes/no)

In this example a systolic blood pressure from a sample that is above 140 mmHg is considered an event of the patient with hypertension. Based on published literature the proportion of patients in the general population with hypertension is 30%. The evaluator wishes to detect a clinically relevant difference of 10% in systolic blood pressure as an outcome between the intervention group with cds and the control group without cds . This means the expected proportion of patients with hypertension is 20% (p1 = 0.2) in the intervention group and 30% (p2 = 0.3) in the control group. Assuming a significance level or alpha of 0.05 for 2-tailed t -test and power of 0.80 the corresponding multipliers are 1.96 and 0.842, respectively. Using the sample size equation for categorical outcome below, we can calculate the sample size needed for the above study.

n = [(a+b)2(p1q1+p2q2)]/χ2

p1 = proportion of patients with hypertension in intervention group

q1 = proportion of patients without hypertension in intervention group (or 1-p1)

p2 = proportion of patients with hypertension in control group

q2 = proportion of patients without hypertension in control group (or 1-p2)

χ = desired difference in proportion of hypertensive patients between two groups

Providing the values in the equation would give the sample size (n) of 291 samples per group as the result

n = [(1.96+0.842)2((0.2)(0.8)+(0.3)(0.7))]/(0.1)2 or 291 samples per group

From Table 3 on p. 1392 of Noordzij et al. (2010).

This publication is licensed under a Creative Commons License, Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0): see https://creativecommons.org/licenses/by-nc/4.0/

  • Cite this Page Lau F, Holbrook A. Chapter 10 Methods for Comparative Studies. In: Lau F, Kuziemsky C, editors. Handbook of eHealth Evaluation: An Evidence-based Approach [Internet]. Victoria (BC): University of Victoria; 2017 Feb 27.
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Quantitative Research Hypothesis Examples

Quantitative Research Hypothesis Examples

In general, a researcher arranges hypotheses based on the formulation of problems and theoretical studies. For quantitative research, the hypothesis used is a statistical hypothesis, meaning that the hypothesis must be tested using statistical rules. Whereas for qualitative research does not need to use statistical rules. In a quantitative study, the formulated statistical hypothesis has two forms, the null hypothesis (Ho) and the alternative hypothesis (Ha). In general, hypotheses for quantitative research have three types: Descriptive Hypothesis, Comparative Hypothesis, and Associative Hypothesis.

Descriptive Hypothesis

Descriptive hypotheses are temporary conjectures about the value of a variable, not expressing relationships or comparisons. Remember, only about the value of a variable. Statistics used to test descriptive hypotheses are sample mean tests or standard deviation tests. A researcher formulates hypothesis based on the problem formulation and theoretical study. Following are some examples of problem formulations (PF), hypotheses (H). PF: What is the percentage of junior high school mathematics mastery in the subject matter of the set? H: Junior high school mathematics teacher mastery in the subject matter reaches 70%.

PF: How good is the grade XI mastery of class XI material? H: mastery of class X material by class XI students reaches 75%.

Comparative Hypothesis

The comparative hypothesis is a temporary construct that compares the values ​​of two variables. That is, in the comparative hypothesis, we do not determine with certainty the value of the variables we examine, but compare. Means, there are two variables that are the same, but different samples. The statistics used to test this comparative hypothesis are (assuming normality is met) using a t-test. But before that, the normality and homogeneity must be tested first. Following are some examples of problem formulations (PF), hypotheses (H). PF: Is there a difference in the problem-solving abilities of students who got X learning better than students who got Y learning? H: the problem solving ability of students who get learning X is better than students who get learning Y.

PF: Are there differences in the critical thinking skills of students who study during the day are better than students who study in the morning? H: there is no difference in the critical thinking skills of students who study in the afternoon with students who study in the morning.

The two hypothetical examples above are slightly different. In the first hypothesis, we claim that the problem solving ability of students who get learning X is better than students who get learning Y. While in the second hypothesis, there is no one-sided claim that the critical thinking skills of students who learn during the day are better or worse. We only state that there are differences. Which problem is better, it does not concern this hypothesis. The first hypothesis is a one-party test hypothesis, while the second hypothesis is called a two-party test hypothesis.

Associative Quantitative Hypothesis

The associative hypothesis is a relationship between the relationship between two variables, the dependent variable and the independent variable. The statistics are used to test this comparative hypothesis are (assuming normality is met) using Product Moment Correlation, Double Correlation, or Partial Correlation. The following are examples of problem formulations (PF), hypotheses (H). PF: Is there a relationship between student achievement and the level of student anxiety? H: there is a negative relationship between student achievement with the level of student anxiety.

PF: Is there a relationship between student learning outcomes and seating arrangements? H: there is a positive relationship between student achievement with the level of student anxiety. In the first hypothesis there are the words ‘negative relationship’. Negative relationship means inversely proportional. That is if the level of student anxiety is high, then student achievement is low. Whereas in the second hypothesis there are the words ‘positive relationship’. Positive relationship means directly proportional. It means if the seating arrangement is good, the student learning outcomes are high.

example of hypothesis in a comparative study

How to Write a Hypothesis? Types and Examples 

how to write a hypothesis for research

All research studies involve the use of the scientific method, which is a mathematical and experimental technique used to conduct experiments by developing and testing a hypothesis or a prediction about an outcome. Simply put, a hypothesis is a suggested solution to a problem. It includes elements that are expressed in terms of relationships with each other to explain a condition or an assumption that hasn’t been verified using facts. 1 The typical steps in a scientific method include developing such a hypothesis, testing it through various methods, and then modifying it based on the outcomes of the experiments.  

A research hypothesis can be defined as a specific, testable prediction about the anticipated results of a study. 2 Hypotheses help guide the research process and supplement the aim of the study. After several rounds of testing, hypotheses can help develop scientific theories. 3 Hypotheses are often written as if-then statements. 

Here are two hypothesis examples: 

Dandelions growing in nitrogen-rich soils for two weeks develop larger leaves than those in nitrogen-poor soils because nitrogen stimulates vegetative growth. 4  

If a company offers flexible work hours, then their employees will be happier at work. 5  

Table of Contents

  • What is a hypothesis? 
  • Types of hypotheses 
  • Characteristics of a hypothesis 
  • Functions of a hypothesis 
  • How to write a hypothesis 
  • Hypothesis examples 
  • Frequently asked questions 

What is a hypothesis?

Figure 1. Steps in research design

A hypothesis expresses an expected relationship between variables in a study and is developed before conducting any research. Hypotheses are not opinions but rather are expected relationships based on facts and observations. They help support scientific research and expand existing knowledge. An incorrectly formulated hypothesis can affect the entire experiment leading to errors in the results so it’s important to know how to formulate a hypothesis and develop it carefully.

A few sources of a hypothesis include observations from prior studies, current research and experiences, competitors, scientific theories, and general conditions that can influence people. Figure 1 depicts the different steps in a research design and shows where exactly in the process a hypothesis is developed. 4  

There are seven different types of hypotheses—simple, complex, directional, nondirectional, associative and causal, null, and alternative. 

Types of hypotheses

The seven types of hypotheses are listed below: 5 , 6,7  

  • Simple : Predicts the relationship between a single dependent variable and a single independent variable. 

Example: Exercising in the morning every day will increase your productivity.  

  • Complex : Predicts the relationship between two or more variables. 

Example: Spending three hours or more on social media daily will negatively affect children’s mental health and productivity, more than that of adults.  

  • Directional : Specifies the expected direction to be followed and uses terms like increase, decrease, positive, negative, more, or less. 

Example: The inclusion of intervention X decreases infant mortality compared to the original treatment.  

  • Non-directional : Does not predict the exact direction, nature, or magnitude of the relationship between two variables but rather states the existence of a relationship. This hypothesis may be used when there is no underlying theory or if findings contradict prior research. 

Example: Cats and dogs differ in the amount of affection they express.  

  • Associative and causal : An associative hypothesis suggests an interdependency between variables, that is, how a change in one variable changes the other.  

Example: There is a positive association between physical activity levels and overall health.  

A causal hypothesis, on the other hand, expresses a cause-and-effect association between variables. 

Example: Long-term alcohol use causes liver damage.  

  • Null : Claims that the original hypothesis is false by showing that there is no relationship between the variables. 

Example: Sleep duration does not have any effect on productivity.  

  • Alternative : States the opposite of the null hypothesis, that is, a relationship exists between two variables. 

Example: Sleep duration affects productivity.  

example of hypothesis in a comparative study

Characteristics of a hypothesis

So, what makes a good hypothesis? Here are some important characteristics of a hypothesis. 8,9  

  • Testable : You must be able to test the hypothesis using scientific methods to either accept or reject the prediction. 
  • Falsifiable : It should be possible to collect data that reject rather than support the hypothesis. 
  • Logical : Hypotheses shouldn’t be a random guess but rather should be based on previous theories, observations, prior research, and logical reasoning. 
  • Positive : The hypothesis statement about the existence of an association should be positive, that is, it should not suggest that an association does not exist. Therefore, the language used and knowing how to phrase a hypothesis is very important. 
  • Clear and accurate : The language used should be easily comprehensible and use correct terminology. 
  • Relevant : The hypothesis should be relevant and specific to the research question. 
  • Structure : Should include all the elements that make a good hypothesis: variables, relationship, and outcome. 

Functions of a hypothesis

The following list mentions some important functions of a hypothesis: 1  

  • Maintains the direction and progress of the research. 
  • Expresses the important assumptions underlying the proposition in a single statement. 
  • Establishes a suitable context for researchers to begin their investigation and for readers who are referring to the final report. 
  • Provides an explanation for the occurrence of a specific phenomenon. 
  • Ensures selection of appropriate and accurate facts necessary and relevant to the research subject. 

To summarize, a hypothesis provides the conceptual elements that complete the known data, conceptual relationships that systematize unordered elements, and conceptual meanings and interpretations that explain the unknown phenomena. 1  

example of hypothesis in a comparative study

How to write a hypothesis

Listed below are the main steps explaining how to write a hypothesis. 2,4,5  

  • Make an observation and identify variables : Observe the subject in question and try to recognize a pattern or a relationship between the variables involved. This step provides essential background information to begin your research.  

For example, if you notice that an office’s vending machine frequently runs out of a specific snack, you may predict that more people in the office choose that snack over another. 

  • Identify the main research question : After identifying a subject and recognizing a pattern, the next step is to ask a question that your hypothesis will answer.  

For example, after observing employees’ break times at work, you could ask “why do more employees take breaks in the morning rather than in the afternoon?” 

  • Conduct some preliminary research to ensure originality and novelty : Your initial answer, which is your hypothesis, to the question is based on some pre-existing information about the subject. However, to ensure that your hypothesis has not been asked before or that it has been asked but rejected by other researchers you would need to gather additional information.  

For example, based on your observations you might state a hypothesis that employees work more efficiently when the air conditioning in the office is set at a lower temperature. However, during your preliminary research you find that this hypothesis was proven incorrect by a prior study. 

  • Develop a general statement : After your preliminary research has confirmed the originality of your proposed answer, draft a general statement that includes all variables, subjects, and predicted outcome. The statement could be if/then or declarative.  
  • Finalize the hypothesis statement : Use the PICOT model, which clarifies how to word a hypothesis effectively, when finalizing the statement. This model lists the important components required to write a hypothesis. 

P opulation: The specific group or individual who is the main subject of the research 

I nterest: The main concern of the study/research question 

C omparison: The main alternative group 

O utcome: The expected results  

T ime: Duration of the experiment 

Once you’ve finalized your hypothesis statement you would need to conduct experiments to test whether the hypothesis is true or false. 

Hypothesis examples

The following table provides examples of different types of hypotheses. 10 ,11  

   
Null Hyperactivity is not related to eating sugar. 
There is no relationship between height and shoe size. 
Alternative Hyperactivity is positively related to eating sugar. 
There is a positive association between height and shoe size. 
Simple Students who eat breakfast perform better in exams than students who don’t eat breakfast. 
Reduced screen time improves sleep quality. 
Complex People with high-sugar diet and sedentary activity levels are more likely to develop depression. 
Motorists who talk on the phone while driving will be more likely to make errors on a driving course than those who do not talk on the phone. 
Directional As job satisfaction increases, the rate of employee turnover decreases. 
Increase in sun exposure increases the risk of skin cancer. 
Non-directional College students will perform differently from elementary school students on a memory task. 
Advertising exposure correlates with variations in purchase decisions among consumers. 
Associative Hospitals have more sick people in them than other institutions in society. 
Watching TV is related to increased snacking. 
Causal Inadequate sleep decreases memory retention. 
Recreational drugs cause psychosis. 

example of hypothesis in a comparative study

Key takeaways  

Here’s a summary of all the key points discussed in this article about how to write a hypothesis. 

  • A hypothesis is an assumption about an association between variables made based on limited evidence, which should be tested. 
  • A hypothesis has four parts—the research question, independent variable, dependent variable, and the proposed relationship between the variables.   
  • The statement should be clear, concise, testable, logical, and falsifiable. 
  • There are seven types of hypotheses—simple, complex, directional, non-directional, associative and causal, null, and alternative. 
  • A hypothesis provides a focus and direction for the research to progress. 
  • A hypothesis plays an important role in the scientific method by helping to create an appropriate experimental design. 

Frequently asked questions

Hypotheses and research questions have different objectives and structure. The following table lists some major differences between the two. 9  

   
Includes a prediction based on the proposed research No prediction is made  
Designed to forecast the relationship of and between two or more variables Variables may be explored 
Closed ended Open ended, invites discussion 
Used if the research topic is well established and there is certainty about the relationship between the variables Used for new topics that haven’t been researched extensively. The relationship between different variables is less known 

Here are a few examples to differentiate between a research question and hypothesis. 

   
What is the effect of eating an apple a day by adults aged over 60 years on the frequency of physician visits?  Eating an apple each day, after the age of 60, will result in a reduction of frequency of physician visits 
What is the effect of flexible or fixed working hours on employee job satisfaction? Workplaces that offer flexible working hours report higher levels of employee job satisfaction than workplaces with fixed hours. 
Does drinking coffee in the morning affect employees’ productivity? Drinking coffee in the morning improves employees’ productivity. 

Yes, here’s a simple checklist to help you gauge the effectiveness of your hypothesis. 9   1. When writing a hypothesis statement, check if it:  2. Predicts the relationship between the stated variables and the expected outcome.  3. Uses simple and concise language and is not wordy.  4. Does not assume readers’ knowledge about the subject.  5. Has observable, falsifiable, and testable results. 

As mentioned earlier in this article, a hypothesis is an assumption or prediction about an association between variables based on observations and simple evidence. These statements are usually generic. Research objectives, on the other hand, are more specific and dictated by hypotheses. The same hypothesis can be tested using different methods and the research objectives could be different in each case.     For example, Louis Pasteur observed that food lasts longer at higher altitudes, reasoned that it could be because the air at higher altitudes is cleaner (with fewer or no germs), and tested the hypothesis by exposing food to air cleaned in the laboratory. 12 Thus, a hypothesis is predictive—if the reasoning is correct, X will lead to Y—and research objectives are developed to test these predictions. 

Null hypothesis testing is a method to decide between two assumptions or predictions between variables (null and alternative hypotheses) in a statistical relationship in a sample. The null hypothesis, denoted as H 0 , claims that no relationship exists between variables in a population and any relationship in the sample reflects a sampling error or occurrence by chance. The alternative hypothesis, denoted as H 1 , claims that there is a relationship in the population. In every study, researchers need to decide whether the relationship in a sample occurred by chance or reflects a relationship in the population. This is done by hypothesis testing using the following steps: 13   1. Assume that the null hypothesis is true.  2. Determine how likely the sample relationship would be if the null hypothesis were true. This probability is called the p value.  3. If the sample relationship would be extremely unlikely, reject the null hypothesis and accept the alternative hypothesis. If the relationship would not be unlikely, accept the null hypothesis. 

example of hypothesis in a comparative study

To summarize, researchers should know how to write a good hypothesis to ensure that their research progresses in the required direction. A hypothesis is a testable prediction about any behavior or relationship between variables, usually based on facts and observation, and states an expected outcome.  

We hope this article has provided you with essential insight into the different types of hypotheses and their functions so that you can use them appropriately in your next research project. 

References  

  • Dalen, DVV. The function of hypotheses in research. Proquest website. Accessed April 8, 2024. https://www.proquest.com/docview/1437933010?pq-origsite=gscholar&fromopenview=true&sourcetype=Scholarly%20Journals&imgSeq=1  
  • McLeod S. Research hypothesis in psychology: Types & examples. SimplyPsychology website. Updated December 13, 2023. Accessed April 9, 2024. https://www.simplypsychology.org/what-is-a-hypotheses.html  
  • Scientific method. Britannica website. Updated March 14, 2024. Accessed April 9, 2024. https://www.britannica.com/science/scientific-method  
  • The hypothesis in science writing. Accessed April 10, 2024. https://berks.psu.edu/sites/berks/files/campus/HypothesisHandout_Final.pdf  
  • How to develop a hypothesis (with elements, types, and examples). Indeed.com website. Updated February 3, 2023. Accessed April 10, 2024. https://www.indeed.com/career-advice/career-development/how-to-write-a-hypothesis  
  • Types of research hypotheses. Excelsior online writing lab. Accessed April 11, 2024. https://owl.excelsior.edu/research/research-hypotheses/types-of-research-hypotheses/  
  • What is a research hypothesis: how to write it, types, and examples. Researcher.life website. Published February 8, 2023. Accessed April 11, 2024. https://researcher.life/blog/article/how-to-write-a-research-hypothesis-definition-types-examples/  
  • Developing a hypothesis. Pressbooks website. Accessed April 12, 2024. https://opentext.wsu.edu/carriecuttler/chapter/developing-a-hypothesis/  
  • What is and how to write a good hypothesis in research. Elsevier author services website. Accessed April 12, 2024. https://scientific-publishing.webshop.elsevier.com/manuscript-preparation/what-how-write-good-hypothesis-research/  
  • How to write a great hypothesis. Verywellmind website. Updated March 12, 2023. Accessed April 13, 2024. https://www.verywellmind.com/what-is-a-hypothesis-2795239  
  • 15 Hypothesis examples. Helpfulprofessor.com Published September 8, 2023. Accessed March 14, 2024. https://helpfulprofessor.com/hypothesis-examples/ 
  • Editage insights. What is the interconnectivity between research objectives and hypothesis? Published February 24, 2021. Accessed April 13, 2024. https://www.editage.com/insights/what-is-the-interconnectivity-between-research-objectives-and-hypothesis  
  • Understanding null hypothesis testing. BCCampus open publishing. Accessed April 16, 2024. https://opentextbc.ca/researchmethods/chapter/understanding-null-hypothesis-testing/#:~:text=In%20null%20hypothesis%20testing%2C%20this,said%20to%20be%20statistically%20significant  

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What is comparative analysis? A complete guide

Last updated

18 April 2023

Reviewed by

Jean Kaluza

Short on time? Get an AI generated summary of this article instead

Comparative analysis is a valuable tool for acquiring deep insights into your organization’s processes, products, and services so you can continuously improve them. 

Similarly, if you want to streamline, price appropriately, and ultimately be a market leader, you’ll likely need to draw on comparative analyses quite often.

When faced with multiple options or solutions to a given problem, a thorough comparative analysis can help you compare and contrast your options and make a clear, informed decision.

If you want to get up to speed on conducting a comparative analysis or need a refresher, here’s your guide.

Make comparative analysis less tedious

Dovetail streamlines comparative analysis to help you uncover and share actionable insights

  • What exactly is comparative analysis?

A comparative analysis is a side-by-side comparison that systematically compares two or more things to pinpoint their similarities and differences. The focus of the investigation might be conceptual—a particular problem, idea, or theory—or perhaps something more tangible, like two different data sets.

For instance, you could use comparative analysis to investigate how your product features measure up to the competition.

After a successful comparative analysis, you should be able to identify strengths and weaknesses and clearly understand which product is more effective.

You could also use comparative analysis to examine different methods of producing that product and determine which way is most efficient and profitable.

The potential applications for using comparative analysis in everyday business are almost unlimited. That said, a comparative analysis is most commonly used to examine

Emerging trends and opportunities (new technologies, marketing)

Competitor strategies

Financial health

Effects of trends on a target audience

Free AI content analysis generator

Make sense of your research by automatically summarizing key takeaways through our free content analysis tool.

example of hypothesis in a comparative study

  • Why is comparative analysis so important? 

Comparative analysis can help narrow your focus so your business pursues the most meaningful opportunities rather than attempting dozens of improvements simultaneously.

A comparative approach also helps frame up data to illuminate interrelationships. For example, comparative research might reveal nuanced relationships or critical contexts behind specific processes or dependencies that wouldn’t be well-understood without the research.

For instance, if your business compares the cost of producing several existing products relative to which ones have historically sold well, that should provide helpful information once you’re ready to look at developing new products or features.

  • Comparative vs. competitive analysis—what’s the difference?

Comparative analysis is generally divided into three subtypes, using quantitative or qualitative data and then extending the findings to a larger group. These include

Pattern analysis —identifying patterns or recurrences of trends and behavior across large data sets.

Data filtering —analyzing large data sets to extract an underlying subset of information. It may involve rearranging, excluding, and apportioning comparative data to fit different criteria. 

Decision tree —flowcharting to visually map and assess potential outcomes, costs, and consequences.

In contrast, competitive analysis is a type of comparative analysis in which you deeply research one or more of your industry competitors. In this case, you’re using qualitative research to explore what the competition is up to across one or more dimensions.

For example

Service delivery —metrics like the Net Promoter Scores indicate customer satisfaction levels.

Market position — the share of the market that the competition has captured.

Brand reputation —how well-known or recognized your competitors are within their target market.

  • Tips for optimizing your comparative analysis

Conduct original research

Thorough, independent research is a significant asset when doing comparative analysis. It provides evidence to support your findings and may present a perspective or angle not considered previously. 

Make analysis routine

To get the maximum benefit from comparative research, make it a regular practice, and establish a cadence you can realistically stick to. Some business areas you could plan to analyze regularly include:

Profitability

Competition

Experiment with controlled and uncontrolled variables

In addition to simply comparing and contrasting, explore how different variables might affect your outcomes.

For example, a controllable variable would be offering a seasonal feature like a shopping bot to assist in holiday shopping or raising or lowering the selling price of a product.

Uncontrollable variables include weather, changing regulations, the current political climate, or global pandemics.

Put equal effort into each point of comparison

Most people enter into comparative research with a particular idea or hypothesis already in mind to validate. For instance, you might try to prove the worthwhileness of launching a new service. So, you may be disappointed if your analysis results don’t support your plan.

However, in any comparative analysis, try to maintain an unbiased approach by spending equal time debating the merits and drawbacks of any decision. Ultimately, this will be a practical, more long-term sustainable approach for your business than focusing only on the evidence that favors pursuing your argument or strategy.

Writing a comparative analysis in five steps

To put together a coherent, insightful analysis that goes beyond a list of pros and cons or similarities and differences, try organizing the information into these five components:

1. Frame of reference

Here is where you provide context. First, what driving idea or problem is your research anchored in? Then, for added substance, cite existing research or insights from a subject matter expert, such as a thought leader in marketing, startup growth, or investment

2. Grounds for comparison Why have you chosen to examine the two things you’re analyzing instead of focusing on two entirely different things? What are you hoping to accomplish?

3. Thesis What argument or choice are you advocating for? What will be the before and after effects of going with either decision? What do you anticipate happening with and without this approach?

For example, “If we release an AI feature for our shopping cart, we will have an edge over the rest of the market before the holiday season.” The finished comparative analysis will weigh all the pros and cons of choosing to build the new expensive AI feature including variables like how “intelligent” it will be, what it “pushes” customers to use, how much it takes off the plates of customer service etc.

Ultimately, you will gauge whether building an AI feature is the right plan for your e-commerce shop.

4. Organize the scheme Typically, there are two ways to organize a comparative analysis report. First, you can discuss everything about comparison point “A” and then go into everything about aspect “B.” Or, you alternate back and forth between points “A” and “B,” sometimes referred to as point-by-point analysis.

Using the AI feature as an example again, you could cover all the pros and cons of building the AI feature, then discuss the benefits and drawbacks of building and maintaining the feature. Or you could compare and contrast each aspect of the AI feature, one at a time. For example, a side-by-side comparison of the AI feature to shopping without it, then proceeding to another point of differentiation.

5. Connect the dots Tie it all together in a way that either confirms or disproves your hypothesis.

For instance, “Building the AI bot would allow our customer service team to save 12% on returns in Q3 while offering optimizations and savings in future strategies. However, it would also increase the product development budget by 43% in both Q1 and Q2. Our budget for product development won’t increase again until series 3 of funding is reached, so despite its potential, we will hold off building the bot until funding is secured and more opportunities and benefits can be proved effective.”

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  • Choosing the Right Statistical Test | Types & Examples

Choosing the Right Statistical Test | Types & Examples

Published on January 28, 2020 by Rebecca Bevans . Revised on June 22, 2023.

Statistical tests are used in hypothesis testing . They can be used to:

  • determine whether a predictor variable has a statistically significant relationship with an outcome variable.
  • estimate the difference between two or more groups.

Statistical tests assume a null hypothesis of no relationship or no difference between groups. Then they determine whether the observed data fall outside of the range of values predicted by the null hypothesis.

If you already know what types of variables you’re dealing with, you can use the flowchart to choose the right statistical test for your data.

Statistical tests flowchart

Table of contents

What does a statistical test do, when to perform a statistical test, choosing a parametric test: regression, comparison, or correlation, choosing a nonparametric test, flowchart: choosing a statistical test, other interesting articles, frequently asked questions about statistical tests.

Statistical tests work by calculating a test statistic – a number that describes how much the relationship between variables in your test differs from the null hypothesis of no relationship.

It then calculates a p value (probability value). The p -value estimates how likely it is that you would see the difference described by the test statistic if the null hypothesis of no relationship were true.

If the value of the test statistic is more extreme than the statistic calculated from the null hypothesis, then you can infer a statistically significant relationship between the predictor and outcome variables.

If the value of the test statistic is less extreme than the one calculated from the null hypothesis, then you can infer no statistically significant relationship between the predictor and outcome variables.

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You can perform statistical tests on data that have been collected in a statistically valid manner – either through an experiment , or through observations made using probability sampling methods .

For a statistical test to be valid , your sample size needs to be large enough to approximate the true distribution of the population being studied.

To determine which statistical test to use, you need to know:

  • whether your data meets certain assumptions.
  • the types of variables that you’re dealing with.

Statistical assumptions

Statistical tests make some common assumptions about the data they are testing:

  • Independence of observations (a.k.a. no autocorrelation): The observations/variables you include in your test are not related (for example, multiple measurements of a single test subject are not independent, while measurements of multiple different test subjects are independent).
  • Homogeneity of variance : the variance within each group being compared is similar among all groups. If one group has much more variation than others, it will limit the test’s effectiveness.
  • Normality of data : the data follows a normal distribution (a.k.a. a bell curve). This assumption applies only to quantitative data .

If your data do not meet the assumptions of normality or homogeneity of variance, you may be able to perform a nonparametric statistical test , which allows you to make comparisons without any assumptions about the data distribution.

If your data do not meet the assumption of independence of observations, you may be able to use a test that accounts for structure in your data (repeated-measures tests or tests that include blocking variables).

Types of variables

The types of variables you have usually determine what type of statistical test you can use.

Quantitative variables represent amounts of things (e.g. the number of trees in a forest). Types of quantitative variables include:

  • Continuous (aka ratio variables): represent measures and can usually be divided into units smaller than one (e.g. 0.75 grams).
  • Discrete (aka integer variables): represent counts and usually can’t be divided into units smaller than one (e.g. 1 tree).

Categorical variables represent groupings of things (e.g. the different tree species in a forest). Types of categorical variables include:

  • Ordinal : represent data with an order (e.g. rankings).
  • Nominal : represent group names (e.g. brands or species names).
  • Binary : represent data with a yes/no or 1/0 outcome (e.g. win or lose).

Choose the test that fits the types of predictor and outcome variables you have collected (if you are doing an experiment , these are the independent and dependent variables ). Consult the tables below to see which test best matches your variables.

Parametric tests usually have stricter requirements than nonparametric tests, and are able to make stronger inferences from the data. They can only be conducted with data that adheres to the common assumptions of statistical tests.

The most common types of parametric test include regression tests, comparison tests, and correlation tests.

Regression tests

Regression tests look for cause-and-effect relationships . They can be used to estimate the effect of one or more continuous variables on another variable.

Predictor variable Outcome variable Research question example
What is the effect of income on longevity?
What is the effect of income and minutes of exercise per day on longevity?
Logistic regression What is the effect of drug dosage on the survival of a test subject?

Comparison tests

Comparison tests look for differences among group means . They can be used to test the effect of a categorical variable on the mean value of some other characteristic.

T-tests are used when comparing the means of precisely two groups (e.g., the average heights of men and women). ANOVA and MANOVA tests are used when comparing the means of more than two groups (e.g., the average heights of children, teenagers, and adults).

Predictor variable Outcome variable Research question example
Paired t-test What is the effect of two different test prep programs on the average exam scores for students from the same class?
Independent t-test What is the difference in average exam scores for students from two different schools?
ANOVA What is the difference in average pain levels among post-surgical patients given three different painkillers?
MANOVA What is the effect of flower species on petal length, petal width, and stem length?

Correlation tests

Correlation tests check whether variables are related without hypothesizing a cause-and-effect relationship.

These can be used to test whether two variables you want to use in (for example) a multiple regression test are autocorrelated.

Variables Research question example
Pearson’s  How are latitude and temperature related?

Non-parametric tests don’t make as many assumptions about the data, and are useful when one or more of the common statistical assumptions are violated. However, the inferences they make aren’t as strong as with parametric tests.

Predictor variable Outcome variable Use in place of…
Spearman’s 
Pearson’s 
Sign test One-sample -test
Kruskal–Wallis  ANOVA
ANOSIM MANOVA
Wilcoxon Rank-Sum test Independent t-test
Wilcoxon Signed-rank test Paired t-test

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example of hypothesis in a comparative study

This flowchart helps you choose among parametric tests. For nonparametric alternatives, check the table above.

Choosing the right statistical test

If you want to know more about statistics , methodology , or research bias , make sure to check out some of our other articles with explanations and examples.

  • Normal distribution
  • Descriptive statistics
  • Measures of central tendency
  • Correlation coefficient
  • Null hypothesis

Methodology

  • Cluster sampling
  • Stratified sampling
  • Types of interviews
  • Cohort study
  • Thematic analysis

Research bias

  • Implicit bias
  • Cognitive bias
  • Survivorship bias
  • Availability heuristic
  • Nonresponse bias
  • Regression to the mean

Statistical tests commonly assume that:

  • the data are normally distributed
  • the groups that are being compared have similar variance
  • the data are independent

If your data does not meet these assumptions you might still be able to use a nonparametric statistical test , which have fewer requirements but also make weaker inferences.

A test statistic is a number calculated by a  statistical test . It describes how far your observed data is from the  null hypothesis  of no relationship between  variables or no difference among sample groups.

The test statistic tells you how different two or more groups are from the overall population mean , or how different a linear slope is from the slope predicted by a null hypothesis . Different test statistics are used in different statistical tests.

Statistical significance is a term used by researchers to state that it is unlikely their observations could have occurred under the null hypothesis of a statistical test . Significance is usually denoted by a p -value , or probability value.

Statistical significance is arbitrary – it depends on the threshold, or alpha value, chosen by the researcher. The most common threshold is p < 0.05, which means that the data is likely to occur less than 5% of the time under the null hypothesis .

When the p -value falls below the chosen alpha value, then we say the result of the test is statistically significant.

Quantitative variables are any variables where the data represent amounts (e.g. height, weight, or age).

Categorical variables are any variables where the data represent groups. This includes rankings (e.g. finishing places in a race), classifications (e.g. brands of cereal), and binary outcomes (e.g. coin flips).

You need to know what type of variables you are working with to choose the right statistical test for your data and interpret your results .

Discrete and continuous variables are two types of quantitative variables :

  • Discrete variables represent counts (e.g. the number of objects in a collection).
  • Continuous variables represent measurable amounts (e.g. water volume or weight).

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example of hypothesis in a comparative study

Causal Comparative Research: Methods And Examples

Ritu was in charge of marketing a new protein drink about to be launched. The client wanted a causal-comparative study…

Causal Comparative Research

Ritu was in charge of marketing a new protein drink about to be launched. The client wanted a causal-comparative study highlighting the drink’s benefits. They demanded that comparative analysis be made the main campaign design strategy. After carefully analyzing the project requirements, Ritu decided to follow a causal-comparative research design. She realized that causal-comparative research emphasizing physical development in different groups of people would lay a good foundation to establish the product.

What Is Causal Comparative Research?

Examples of causal comparative research variables.

Causal-comparative research is a method used to identify the cause–effect relationship between a dependent and independent variable. This relationship is usually a suggested relationship because we can’t control an independent variable completely. Unlike correlation research, this doesn’t rely on relationships. In a causal-comparative research design, the researcher compares two groups to find out whether the independent variable affected the outcome or the dependent variable.

A causal-comparative method determines whether one variable has a direct influence on the other and why. It identifies the causes of certain occurrences (or non-occurrences). It makes a study descriptive rather than experimental by scrutinizing the relationships among different variables in which the independent variable has already occurred. Variables can’t be manipulated sometimes, but a link between dependent and independent variables is established and the implications of possible causes are used to draw conclusions.

In a causal-comparative design, researchers study cause and effect in retrospect and determine consequences or causes of differences already existing among or between groups of people.

Let’s look at some characteristics of causal-comparative research:

  • This method tries to identify cause and effect relationships.
  • Two or more groups are included as variables.
  • Individuals aren’t selected randomly.
  • Independent variables can’t be manipulated.
  • It helps save time and money.

The main purpose of a causal-comparative study is to explore effects, consequences and causes. There are two types of causal-comparative research design. They are:

Retrospective Causal Comparative Research

For this type of research, a researcher has to investigate a particular question after the effects have occurred. They attempt to determine whether or not a variable influences another variable.

Prospective Causal Comparative Research

The researcher initiates a study, beginning with the causes and determined to analyze the effects of a given condition. This is not as common as retrospective causal-comparative research.

Usually, it’s easier to compare a variable with the known than the unknown.

Researchers use causal-comparative research to achieve research goals by comparing two variables that represent two groups. This data can include differences in opportunities, privileges exclusive to certain groups or developments with respect to gender, race, nationality or ability.

For example, to find out the difference in wages between men and women, researchers have to make a comparative study of wages earned by both genders across various professions, hierarchies and locations. None of the variables can be influenced and cause-effect relationship has to be established with a persuasive logical argument. Some common variables investigated in this type of research are:

  • Achievement and other ability variables
  • Family-related variables
  • Organismic variables such as age, sex and ethnicity
  • Variables related to schools
  • Personality variables

While raw test scores, assessments and other measures (such as grade point averages) are used as data in this research, sources, standardized tests, structured interviews and surveys are popular research tools.

However, there are drawbacks of causal-comparative research too, such as its inability to manipulate or control an independent variable and the lack of randomization. Subject-selection bias always remains a possibility and poses a threat to the internal validity of a study. Researchers can control it with statistical matching or by creating identical subgroups. Executives have to look out for loss of subjects, location influences, poor attitude of subjects and testing threats to produce a valid research study.

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Restoration of Modern Architecture – Comparative Analysis of 3 Case Studies: Mies van der Rohe Pavilion in Barcelona, Le Corbusier Pavilion in Zurich and BiH History Museum in Sarajevo

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example of hypothesis in a comparative study

  • Adi Ćorović   ORCID: orcid.org/0000-0003-0775-0587 12  

Part of the book series: Lecture Notes in Networks and Systems ((LNNS,volume 851))

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In the restoration of modern architecture, the same dilemmas arise as in the restoration of other types of architectural heritage. Attempts to preserve every authentic part of the whole often prove impossible or out of historical context. An example of this type of attempt is the reconstruction of the German Pavilion in Barcelona by Mies van der Rohe. In this case, restorers opted for the approach known as How it was, where it was , which usually involves trying to make “faithful” replicas of the missing parts, difficult in some cases because it often concerns executions made by experimental techniques or characteristics for a specific period in the past. On the other hand, in the spirit of critical restoration, the solution was seen in the conservation of the architectural heritage which is not opposed to the use of contemporary architectural expression. Practical activities such as the restoration of the Le Corbusier Pavilion in Zurich, which was carried out in accordance with a case-by-case approach, represent a clear reference and significant contribution directed towards the development not only of contemporary restoration practice but also of the theory of restoration. Hybrid approaches to the restoration of modern architectural heritage coexist, exhibiting conceptual and technical contradictions, especially in parts of the world where cataclysmic events, such as wars aimed at the destruction of historical heritage, have upset the practice of restoration based on solid theoretical foundations. As an example of this approach is possible to recognize the restoration activities related to the BiH History Museum in Sarajevo.

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Ćorović, A. (2024). Restoration of Modern Architecture – Comparative Analysis of 3 Case Studies: Mies van der Rohe Pavilion in Barcelona, Le Corbusier Pavilion in Zurich and BiH History Museum in Sarajevo. In: Ademović, N., Tufek-Memišević, T., Arslanagić-Kalajdžić, M. (eds) Interdisciplinary Advances in Sustainable Development III. BHAAAS 2024. Lecture Notes in Networks and Systems, vol 851. Springer, Cham. https://doi.org/10.1007/978-3-031-71076-6_3

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A comparative study of sentiment classification models for greek reviews.

example of hypothesis in a comparative study

1. Introduction

2. theoretical background and review, 2.1. text representation, 2.2. computational methods for sentiment classification, 2.3. related research for greek sentiment classification, 3. methodology, 3.1. dataset selection, 3.2. text preprocessing, 3.3. modeling experiments, 3.3.1. machine learning approaches, 3.3.2. artficial neural network models, 3.3.3. transfer learning models, 3.3.4. large language models, 3.4. model evaluation, 4.1. machine learning, 4.2. artificial neural networks, 4.3. transfer learning model, 4.4. large language models, 5. discussion, 6. conclusions, data availability statement, acknowledgments, conflicts of interest.

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Click here to enlarge figure

ML ModelTrainingTesting
AccuracyPrecisionRecallF1 ScoreAccuracyPrecisionRecallF1 Score
LR92.7392.7792.7392.7393.5293.5993.5293.51
KNN81.4383.1181.4381.2280.9383.2280.9380.55
DT83.5383.5683.3883.3283.6883.7083.6883.67
MNB
SVM90.6390.6790.6390.6391.6191.6991.6191.60
RF88.6588.7688.8288.7089.3289.3889.3289.32
AdaBoost89.3589.4389.3589.3590.7790.8390.7790.76
SGB89.4389.4889.4789.4589.4789.4889.4789.47
ML ModelTrainingTesting
AccuracyPrecisionRecallF1 ScoreAccuracyPrecisionRecallF1 Score
LR92.2592.2892.2592.2593.4493.4593.4493.44
KNN88.3488.4888.3488.3388.3388.3588.3388.33
DT82.7982.8082.2982.7782.0782.0882.0782.07
MNB92.3792.7292.3792.3593.0693.3593.0693.05
SVM
RF88.7488.8888.8488.9289.0989.1089.0989.09
AdaBoost89.3089.3289.3089.3089.6389.6489.6389.62
SGB88.0288.1188.1588.1389.7089.7189.7089.70
ML ModelTrainingTesting
AccuracyPrecisionRecallF1 ScoreAccuracyPrecisionRecallF1 Score
LR92.7592.7992.7592.7593.4493.5293.4493.44
MNB
SVM92.6592.6692.6592.6592.8392.8592.8392.83
ML ModelTrainingTesting
AccuracyPrecisionRecallF1 ScoreAccuracyPrecisionRecallF1 Score
LR93.4993.5193.4993.49
MNB92.6592.9692.6592.6493.3693.6393.3693.36
SVM 94.2094.2094.2094.20
Model/
Neurons
TrainingTesting
AccuracyPrecisionRecallF1 ScoreAccuracyPrecisionRecallF1 Score
MLP/6093.6893.7293.6893.6893.7593.7793.7593.74
MLP/7093.7893.8093.7893.7894.5894.5994.5894.58
MLP/8093.7693.7793.7693.7694.2094.2294.2094.20
MLP/90 93.9093.9393.9093.90
MLP/10093.8293.8393.8293.82
Model/
Neurons
TrainingTesting
AccuracyPrecisionRecallF1 ScoreAccuracyPrecisionRecallF1 Score
MLP/6093.3093.3393.3093.3094.5194.5194.5194.51
MLP/70
MLP/8093.7493.7993.7493.7494.0594.0594.0594.05
MLP/9093.7893.8193.7893.7894.5194.5194.5194.51
MLP/10093.7493.7793.7493.7493.9093.9193.9093.90
EpochsTrainingTesting
LossAccuracy (%)LossAccuracy (%)
10.2689.660.1594.74
20.1196.010.1295.42
30.0897.250.1295.88
40.0598.240.1396.03
ModelAccuracyPrecisionRecallF1 Score
GPT-3.5-turbo93.1393.9893.1393.30
GPT-4
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Michailidis, P.D. A Comparative Study of Sentiment Classification Models for Greek Reviews. Big Data Cogn. Comput. 2024 , 8 , 107. https://doi.org/10.3390/bdcc8090107

Michailidis PD. A Comparative Study of Sentiment Classification Models for Greek Reviews. Big Data and Cognitive Computing . 2024; 8(9):107. https://doi.org/10.3390/bdcc8090107

Michailidis, Panagiotis D. 2024. "A Comparative Study of Sentiment Classification Models for Greek Reviews" Big Data and Cognitive Computing 8, no. 9: 107. https://doi.org/10.3390/bdcc8090107

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