chemistry science research topics

100+ Great Chemistry Research Topics

Table of contents

• 1 What are the best chemistry research topics?
• 2 5 Tips for Writing Chemistry Research Papers
• 3 Chemical Engineering Research Topics
• 4 Organic Сhemistry Research Topics
• 5 Іnorganic Сhemistry Research Topics
• 6 Biomolecular Сhemistry Research Topics
• 7 Analytical Chemistry Research Topics
• 8 Computational Chemistry Research Topics
• 9 Physical Chemistry Research Topics
• 10 Innovative Chemistry Research Topics
• 11 Environmental Chemistry Research Topics
• 12 Green Chemistry Research Topics
• 13.1 Conclusion

Do you need a topic for your chemistry research paper? Are you unsure of where to start? Don’t worry – we’re here to help. In this post, we’ll go over a series of the best chemistry research paper topics as well as Tips for Writing Chemistry Research Papers on different topics. By the time you finish reading this post, you’ll have plenty of ideas to get started on your next research project!

There are many different subfields of chemistry, so it can be tough to find interesting chemistry topics to write about. If you’re struggling to narrow down your topic, we’ll go over lists of topics in multiple fields of study.

What are the best chemistry research topics?

Doing research is important to help scientists learn more about the world around us. By researching different compounds and elements, we can learn more about how they interact with one another and how they can be used to create new products or improve existing ones.

There are many different topics that you can choose to research in chemistry. Here are just a few examples:

• The history of chemistry and how it has evolved over time
• How different chemicals react with one another
• How to create new compounds or improve existing ones
• The role of chemistry in the environment
• The health effects of different chemicals

5 Tips for Writing Chemistry Research Papers

Once you have chosen a topic for your research paper , it is important to follow some tips to ensure that your paper is well-written and accurate. Here are a few tips to get you started:

• Start by doing some background research on your topic. This will help you understand the basics of the topic and give you a good foundation to build your paper on.
• Make sure to cite all of the sources that you use in your paper. This will help to show where you got your information and will also help to add credibility to your work.
• Be sure to proofread your paper before you submit it. This will ensure that there are no errors and that your paper is clear and concise.
• Get help from a tutor or friend if you are struggling with your paper. They may be able to offer helpful advice or feedback.
• Take your time when writing your research paper . This is not a race, and it is important to make sure that you do a good job on your research.

By following these tips, you can be sure that your chemistry research paper will be a success! So what are you waiting for? Let’s go over some of the best research paper topics out there.

Chemical Engineering Research Topics

Chemical Engineering is a branch of engineering that deals with the design and application of chemical processes. If you’re wondering how to choose a paper topic, here are some ideas to inspire you:

• How to create new alloy compounds or improve existing ones
• The health effects of the food industry chemicals
• Chemical engineering and sustainable development
• The future of chemical engineering
• Chemical engineering and the food industry
• Chemical engineering and the pharmaceutical industry
• Chemical engineering and the cosmetics industry
• Chemical engineering and the petrochemical industry

These are just a few examples – there are many more possibilities out there! So get started on your research today. Who knows what you might discover!

Organic Сhemistry Research Topics

Organic chemistry is the study of carbon-containing molecules. There are many different organic chemistry research topics that a student could choose to focus on and here are just a few examples of possible research projects in organic chemistry:

• Investigating new methods for synthesizing chiral molecules
• Studying the structure and reactivity of carbon nanotubes
• Investigating metal complexes with organometallic ligands
• Designing benzene derivatives with improved thermal stability
• Exploring new ways to control the stereochemistry of chemical reactions
• Studying the role of enzymes in organic synthesis
• Investigating new strategies for combating drug resistance
• Developing new methods for detecting explosives residues
• Studying the photochemistry of organic molecules
• Studying the behavior of organometallic compounds in biological systems

Іnorganic Сhemistry Research Topics

Inorganic Chemistry is the study of the chemistry of materials that do not contain carbon. Unlike other chemistry research topics, these include elements such as metals, minerals, and inorganic compounds. If you are looking for inorganic chemistry research topics on inorganic chemistry, here are some ideas to get you started:

• How different metals react with one another
• How to create new alloys or improve existing ones
• The role of inorganic chemistry in the environment
• Inorganic chemistry and sustainable development
• The future of inorganic chemistry
• Inorganic chemistry and the food industry
• Inorganic chemistry and the pharmaceutical industry
• Atomic structure progressive scale grading
• Inorganiс Сhemistry and the cosmetics industry

Biomolecular Сhemistry Research Topics

Biomolecular chemistry is the study of molecules that are important for life. These molecules can be found in all living things, from tiny bacteria to the largest animals. Researchers who work in this field use a variety of techniques to learn more about how these molecules function and how they interact with each other.

If you are looking for essential biomolecular chemistry research topics, here are some ideas to get you started:

• The structure and function of DNA
• The structure and function of proteins
• The role of carbohydrates in the body
• The role of lipids in the body
• How enzymes work
• The role of biochemistry in heart disease
• Cyanides and their effect on the body
• The role of biochemistry in cancer treatment
• The role of biochemistry in Parkison’s disease treatment
• The role of biochemistry in the immune system

The possibilities are endless for someone willing to dedicate some time to research.

Analytical Chemistry Research Topics

Analytical Chemistry is a type of chemistry that helps scientists figure out what something is made of. This can be done through a variety of methods, such as spectroscopy or chromatography. If you are looking for research topics, here are some ideas to get you started:

• How food chemicals react with one another
• Mass spectrometry
• Analytical aspects of gas and liquid chromatography
• Analytical chemistry and sustainable development
• Atomic absorption spectroscopy methods and best practices
• Analytical chemistry and the pharmaceutical industry in Ibuprofen consumption
• Analytical chemistry and the cosmetics industry in UV protectors
• Dispersive x-ray analysis of damaged tissues

Analytical chemistry is considered by many a complex science and there is a lot yet to be discovered in the field.

Computational Chemistry Research Topics

Computational chemistry is a way to use computers to help chemists understand chemical reactions. This can be done by simulating reactions or by designing new molecules. If you are looking for essential chemistry research topics in computational chemistry, here are some ideas to get you started:

• Molecular mechanics simulation
• Reaction rates of complex chemical reactions
• Designing new molecules: how can simulation help
• The role of computers in the study of quantum mechanics
• How to use computers to predict chemical reactions
• Using computers to understand organic chemistry
• The future of computational chemistry in organic reactions
• The impacts of simulation on the development of new medications
• Combustion reaction simulation impact on engine development
• Quantum-chemistry simulation review

Computers are cutting-edge technology in chemical research and this relatively new field of study has a ton yet to be explored.

Physical Chemistry Research Topics

Physical chemistry is the study of how matter behaves. It looks at the physical and chemical properties of atoms and molecules and how they interact with each other. If you are looking for physical chemistry research topics, here are some ideas to get you started:

• Standardization of pH scales
• Structure of atom on a quantum scale
• Bonding across atoms and molecules
• The effect of temperature on chemical reactions
• The role of light in in-body chemical reactions
• Chemical kinetics
• Surface tension and its effects on mixtures
• The role of pressure in chemical reactions
• Rates of diffusion in gases and liquids
• The role of entropy in chemical reactions

Here are just a few samples, but there are plenty more options! Start your research right now!

Innovative Chemistry Research Topics

Innovative chemistry is all about coming up with new ideas and ways to do things. This can be anything from creating new materials to finding new ways to make existing products. If you are looking for ground-breaking chemistry research topics, here are some ideas to get you started:

• Amino acids side chain effects in protein folding
• Chemistry in the production of nanomaterials
• The role of enzymes in chemical reactions
• Photocatalysis in 3D printing
• Avoiding pesticides in agriculture
• Combining chemical and biological processes
• Gene modification in medicinal chemistry
• The role of quantum mechanics in chemical reactions
• Astrochemical research on extraterrestrial molecules
• Spectroscopy signatures of pressurized organic components

If you need a hand, there are several sites that also offer research papers for sale and can be a great asset as you work to create your own research papers.

Whatever route you decide to take, good luck! And remember – the sky’s the limit when it comes to research! So get started today and see where your studies may take you. Who knows, you might just make a breakthrough discovery!

Environmental Chemistry Research Topics

Environmental Chemistry is the study of how chemicals interact with the environment. This can include anything from the air we breathe to the water we drink. If you are looking for environmental chemistry research topics, here are some ideas to get you started:

• Plastic effects on ocean life
• Urban ecology
• The role of carbon in climate change
• Air pollution and its effects
• Water pollution and its effects
• Chemicals in food and their effect on the body
• The effect of chemicals on plant life
• Earth temperature prediction models

A lot of research on the environment is being conducted at the moment because the environment is in danger. There are a lot of environmental problems that need to be solved, and research is the key to solving them.

Green Chemistry Research Topics

Green chemistry is the study of how to make products and processes that are environmentally friendly. This can include anything from finding new ways to recycle materials to developing new products that are biodegradable. If you are looking for green chemistry research topics, here are some ideas to get you started:

• Recycling and reuse of materials
• Developing biodegradable materials
• Improving existing recycling processes
• Green chemistry and sustainable development
• The future of green chemistry
• Green chemistry and the food industry
• Green chemistry and the pharmaceutical industry
• Green chemistry and the cosmetics industry

A more environmentally friendly world is something we all aspire for and a lot of research has been conducted on how we can achieve this, making this one of the most promising areas of study. The results have been varied, but there are a few key things we can do to make a difference.

Controversial Chemistry Research Topics

Controversial chemistry is all about hot-button topics that people are passionate about. This can include anything from the use of chemicals in warfare to the health effects of different chemicals. If you are looking for controversial topics to write about , here are some ideas to get you started:

• The use of chemicals in warfare
• Gene modification in human babies
• Bioengineering
• How fast food chemicals affect the human brain
• The role of the government in regulating chemicals
• Evolution of cigarette chemicals over time
• Chemical effects of CBD oils
• Antidepressant chemical reactions
• Synthetic molecules replication methods
• Gene analysis

Controversial research papers often appear in the media before it has been peer-reviewed and published in a scientific journal. The reason for this is that the media is interested in stories that are new, exciting, and generate a lot of debate.

Chemistry is an incredibly diverse and interesting field, with many controversial topics to write about. If you are looking for a research topic, consider the examples listed in this article. With a little bit of effort, you are sure to find a topic that is both interesting and within your skillset.

In order to be a good researcher, it is important to be able to think critically and solve problems. However, innovation in chemistry research can be challenging. When thinking about how to innovate, it is important to consider both the practical and theoretical aspects of your research. Additionally, try to build on the work of others in order to create something new and unique. With a little bit of effort, you are sure to be able to find a topic that is both interesting and within your skillset.

Happy writing!

Readers also enjoyed

WHY WAIT? PLACE AN ORDER RIGHT NOW!

Just fill out the form, press the button, and have no worries!

We use cookies to give you the best experience possible. By continuing we’ll assume you board with our cookie policy.

• Privacy Policy

Home » 300+ Chemistry Research Topics

300+ Chemistry Research Topics

Table of Contents

Chemistry is a fascinating and complex field that explores the composition, properties, and behavior of matter at the molecular and atomic level. As a result, there are numerous chemistry research topics that can be explored, ranging from the development of new materials and drugs to the study of natural compounds and the environment. In this rapidly evolving field, researchers are constantly uncovering new insights and pushing the boundaries of our understanding of chemistry. Whether you are a student, a professional researcher, or simply curious about the world around you, there is always something new to discover in the field of chemistry. In this post, we will explore some of the exciting and important research topics in chemistry today.

Chemistry Research Topics

Chemistry Research Topics are as follows:

Organic Chemistry Research Topics

Organic Chemistry Research Topics are as follows:

• Development of novel synthetic routes for the production of biologically active natural products
• Investigation of reaction mechanisms and kinetics for organic transformations
• Design and synthesis of new catalysts for asymmetric organic reactions
• Synthesis and characterization of chiral compounds for pharmaceutical applications
• Development of sustainable methods for the synthesis of organic molecules using renewable resources
• Discovery of new reaction pathways for the conversion of biomass into high-value chemicals
• Study of molecular recognition and host-guest interactions for drug design
• Design and synthesis of new materials for energy storage and conversion
• Development of efficient and selective methods for C-H functionalization reactions
• Exploration of the reactivity of reactive intermediates such as radicals and carbenes
• Study of supramolecular chemistry and self-assembly of organic molecules
• Development of new methods for the synthesis of heterocyclic compounds
• Investigation of the biological activities and mechanisms of action of natural products
• Synthesis of polymeric materials with controlled architecture and functionality
• Development of new synthetic methodologies for the preparation of bioconjugates
• Investigation of the mechanisms of enzyme catalysis and the design of enzyme inhibitors
• Synthesis and characterization of novel fluorescent probes for biological imaging
• Development of new synthetic strategies for the preparation of carbohydrates and glycoconjugates
• Study of the properties and reactivity of carbon nanomaterials
• Design and synthesis of novel drugs for the treatment of diseases such as cancer, diabetes, and Alzheimer’s disease.

Inorganic Chemistry Research Topics

Inorganic Chemistry Research Topics are as follows:

• Synthesis and characterization of new metal-organic frameworks (MOFs) for gas storage and separation applications
• Development of new catalysts for sustainable chemical synthesis reactions
• Investigation of the electronic and magnetic properties of transition metal complexes for spintronics applications
• Synthesis and characterization of novel nanomaterials for energy storage applications
• Development of new ligands for metal coordination complexes with potential medical applications
• Investigation of the mechanism of metal-catalyzed reactions using advanced spectroscopic techniques
• Synthesis and characterization of new inorganic materials for photocatalytic water splitting
• Development of new materials for electrochemical carbon dioxide reduction reactions
• Investigation of the properties of transition metal oxides for energy storage and conversion applications
• Synthesis and characterization of new metal chalcogenides for optoelectronic applications
• Development of new methods for the preparation of inorganic nanoparticles with controlled size and shape
• Investigation of the reactivity and catalytic properties of metal clusters
• Synthesis and characterization of new metal-organic polyhedra (MOPs) for gas storage and separation applications
• Development of new methods for the synthesis of metal nanoparticles using environmentally friendly reducing agents
• Investigation of the properties of metal-organic frameworks for gas sensing applications
• Synthesis and characterization of new coordination polymers with potential magnetic and electronic properties
• Development of new materials for electrocatalytic water oxidation reactions
• Investigation of the properties of metal-organic frameworks for carbon capture and storage applications
• Synthesis and characterization of new metal-containing polymers with potential applications in electronics and energy storage
• Development of new methods for the synthesis of metal-organic frameworks using green solvents and renewable resources.

Physical Chemistry Research Topics

Physical Chemistry Research Topics are as follows:

• Investigation of the properties and interactions of ionic liquids in aqueous and non-aqueous solutions.
• Development of advanced analytical techniques for the study of protein structure and dynamics.
• Investigation of the thermodynamic properties of supercritical fluids for use in industrial applications.
• Development of novel nanomaterials for energy storage applications.
• Studies of the surface chemistry of catalysts for the optimization of their performance in chemical reactions.
• Development of new methods for the synthesis of complex organic molecules with improved yields and selectivity.
• Investigation of the molecular mechanisms involved in the catalysis of biochemical reactions.
• Development of new strategies for the controlled release of drugs and other bioactive molecules.
• Studies of the interaction of nanoparticles with biological systems for biomedical applications.
• Investigation of the thermodynamic properties of materials under extreme conditions of temperature and pressure.
• Development of new methods for the characterization of materials at the nanoscale.
• Investigation of the electronic and magnetic properties of materials for use in spintronics.
• Development of new materials for energy conversion and storage.
• Studies of the kinetics and thermodynamics of adsorption processes on surfaces.
• Investigation of the transport properties of ionic liquids for use in energy storage and conversion devices.
• Development of new materials for the capture and sequestration of greenhouse gases.
• Studies of the structure and properties of biomolecules for use in drug design and development.
• Investigation of the dynamics of chemical reactions in solution using time-resolved spectroscopic techniques.
• Development of new approaches for the synthesis of metallic and semiconductor nanoparticles with controlled size and shape.
• Studies of the structure and properties of materials for use in electrochemical energy storage devices.

Analytical Chemistry Research Topics

Analytical Chemistry Research Topics are as follows:

• Development and optimization of analytical techniques for the quantification of trace elements in food and environmental samples.
• Design and synthesis of novel analytical probes for the detection of biomolecules in complex matrices.
• Investigation of the fundamental mechanisms involved in the separation and detection of complex mixtures using chromatographic techniques.
• Development of sensors and biosensors for the detection of chemical and biological species in real-time.
• Investigation of the chemical and structural properties of nanomaterials and their applications in analytical chemistry.
• Development and validation of analytical methods for the quantification of contaminants and pollutants in water, air, and soil.
• Investigation of the molecular mechanisms underlying drug metabolism and toxicity using mass spectrometry.
• Development of analytical tools for the identification and quantification of drugs of abuse in biological matrices.
• Investigation of the chemical composition and properties of natural products and their applications in medicine and food science.
• Development of advanced analytical techniques for the characterization of proteins and peptides.
• Investigation of the chemistry and mechanism of action of antioxidants in foods and their impact on human health.
• Development of analytical methods for the detection and quantification of microorganisms in food and environmental samples.
• Investigation of the molecular mechanisms involved in the biosynthesis and degradation of important biomolecules such as proteins, carbohydrates, and lipids.
• Development of analytical methods for the detection and quantification of environmental toxins and their impact on human health.
• Investigation of the structure and properties of biological membranes and their role in drug delivery and disease.
• Development of analytical techniques for the characterization of complex mixtures such as petroleum and crude oil.
• Investigation of the chemistry and mechanism of action of natural and synthetic dyes.
• Development of analytical techniques for the detection and quantification of pharmaceuticals and personal care products in water and wastewater.
• Investigation of the chemical composition and properties of biopolymers and their applications in biomedicine and biomaterials.
• Development of analytical methods for the identification and quantification of essential nutrients and vitamins in food and dietary supplements.

Biochemistry Research Topics

Biochemistry Research Topics are as follows:

• The role of enzymes in metabolic pathways
• The biochemistry of DNA replication and repair
• Protein folding and misfolding diseases
• Lipid metabolism and the pathogenesis of atherosclerosis
• The role of vitamins and minerals in human metabolism
• Biochemistry of cancer and the development of targeted therapies
• The biochemistry of signal transduction pathways and their regulation
• The mechanisms of antibiotic resistance in bacteria
• The biochemistry of neurotransmitters and their roles in behavior and disease
• The role of oxidative stress in aging and age-related diseases
• The biochemistry of microbial fermentation and its applications in industry
• The biochemistry of the immune system and its response to pathogens
• The biochemistry of plant metabolism and its regulation
• The molecular basis of genetic diseases and gene therapy
• The biochemistry of membrane transport and its role in cell function
• The biochemistry of muscle contraction and its regulation
• The role of lipids in membrane structure and function
• The biochemistry of photosynthesis and its regulation
• The biochemistry of RNA splicing and alternative splicing events
• The biochemistry of epigenetics and its regulation in gene expression.

Environmental Chemistry Research Topics

Environmental Chemistry Research Topics are as follows:

• Investigating the effects of microplastics on aquatic ecosystems and their potential impact on human health.
• Examining the impact of climate change on soil quality and nutrient availability in agricultural systems.
• Developing methods to improve the removal of heavy metals from contaminated soils and waterways.
• Assessing the effectiveness of natural and synthetic antioxidants in mitigating the effects of air pollution on human health.
• Investigating the potential for using algae and other microorganisms to sequester carbon dioxide from the atmosphere.
• Studying the role of biodegradable plastics in reducing plastic waste and their impact on the environment.
• Examining the impact of pesticides and other agricultural chemicals on water quality and the health of aquatic organisms.
• Investigating the effects of ocean acidification on marine organisms and ecosystems.
• Developing new materials and technologies to reduce carbon emissions from industrial processes.
• Evaluating the effectiveness of phytoremediation in cleaning up contaminated soils and waterways.
• Studying the impact of microplastics on terrestrial ecosystems and their potential to enter the food chain.
• Developing sustainable methods for managing and recycling electronic waste.
• Investigating the role of natural processes, such as weathering and erosion, in regulating atmospheric carbon dioxide levels.
• Assessing the impact of urbanization on air quality and developing strategies to mitigate pollution in cities.
• Examining the effects of climate change on the distribution and abundance of species in different ecosystems.
• Investigating the impact of ocean currents on the distribution of pollutants and other environmental contaminants.
• Developing new materials and technologies for renewable energy generation and storage.
• Studying the effects of deforestation on soil quality, water availability, and biodiversity.
• Assessing the potential for using waste materials, such as agricultural residues and municipal solid waste, as sources of renewable energy.
• Investigating the role of natural and synthetic chemicals in regulating ecosystem functions, such as nutrient cycling and carbon sequestration.

Polymer Chemistry Research Topics

Polymer Chemistry Research Topics are as follows:

• Development of new monomers for high-performance polymers
• Synthesis and characterization of biodegradable polymers for sustainable packaging
• Design of stimuli-responsive polymers for drug delivery applications
• Investigation of the properties and applications of conductive polymers
• Development of new catalysts for controlled/living polymerization
• Synthesis of polymers with tailored mechanical properties
• Characterization of the structure-property relationship in polymer nanocomposites
• Study of the impact of polymer architecture on material properties
• Design and synthesis of new polymeric materials for energy storage
• Development of high-throughput methods for polymer synthesis and characterization
• Exploration of new strategies for polymer recycling and upcycling
• Synthesis and characterization of responsive polymer networks for smart textiles
• Design of advanced polymer coatings with self-healing properties
• Investigation of the impact of processing conditions on the morphology and properties of polymer materials
• Study of the interactions between polymers and biological systems
• Development of biocompatible polymers for tissue engineering applications
• Synthesis and characterization of block copolymers for advanced membrane applications
• Exploration of the potential of polymer-based sensors and actuators
• Design of novel polymer electrolytes for advanced batteries and fuel cells
• Study of the behavior of polymers under extreme conditions, such as high pressure or temperature.

Materials Chemistry Research Topics

Materials Chemistry Research Topics are as follows:

• Development of new advanced materials for energy storage and conversion
• Synthesis and characterization of nanomaterials for environmental remediation
• Design and fabrication of stimuli-responsive materials for drug delivery
• Investigation of electrocatalytic materials for fuel cells and electrolysis
• Fabrication of flexible and stretchable electronic materials for wearable devices
• Development of novel materials for high-performance electronic devices
• Exploration of organic-inorganic hybrid materials for optoelectronic applications
• Study of corrosion-resistant coatings for metallic materials
• Investigation of biomaterials for tissue engineering and regenerative medicine
• Synthesis and characterization of metal-organic frameworks for gas storage and separation
• Design and fabrication of new materials for water purification
• Investigation of carbon-based materials for supercapacitors and batteries
• Synthesis and characterization of self-healing materials for structural applications
• Development of new materials for catalysis and chemical reactions
• Exploration of magnetic materials for spintronic devices
• Investigation of thermoelectric materials for energy conversion
• Study of 2D materials for electronic and optoelectronic applications
• Development of sustainable and eco-friendly materials for packaging
• Fabrication of advanced materials for sensors and actuators
• Investigation of materials for high-temperature applications such as aerospace and nuclear industries.

Nuclear Chemistry Research Topics

Nuclear Chemistry Research Topics are as follows:

• Nuclear fission and fusion reactions
• Nuclear power plant safety and radiation protection
• Radioactive waste management and disposal
• Nuclear fuel cycle and waste reprocessing
• Nuclear energy and its impact on climate change
• Radiation therapy for cancer treatment
• Radiopharmaceuticals for medical imaging
• Nuclear medicine and its role in diagnostics
• Nuclear forensics and nuclear security
• Isotopic analysis in environmental monitoring and pollution control
• Nuclear magnetic resonance (NMR) spectroscopy
• Nuclear magnetic resonance imaging (MRI)
• Radiation damage in materials and radiation effects on electronic devices
• Nuclear data evaluation and validation
• Nuclear reactors design and optimization
• Nuclear fuel performance and irradiation behavior
• Nuclear energy systems integration and optimization
• Neutron and gamma-ray detection and measurement techniques
• Nuclear astrophysics and cosmology
• Nuclear weapons proliferation and disarmament.

Medicinal Chemistry Research Topics

Medicinal Chemistry Research Topics are as follows:

• Drug discovery and development
• Design and synthesis of novel drugs
• Medicinal chemistry of natural products
• Structure-activity relationships (SAR) of drugs
• Rational drug design using computational methods
• Target identification and validation
• Drug metabolism and pharmacokinetics (DMPK)
• Drug delivery systems
• Development of new antibiotics
• Design of drugs for the treatment of cancer
• Development of drugs for the treatment of neurological disorders
• Medicinal chemistry of peptides and proteins
• Development of drugs for the treatment of infectious diseases
• Discovery of new antiviral agents
• Design of drugs for the treatment of cardiovascular diseases
• Medicinal chemistry of enzyme inhibitors
• Development of drugs for the treatment of inflammatory diseases
• Design of drugs for the treatment of metabolic disorders
• Medicinal chemistry of anti-cancer agents
• Development of drugs for the treatment of rare diseases.

Food Chemistry Research Topics

Food Chemistry Research Topics are as follows:

• Investigating the effect of cooking methods on the nutritional value of food.
• Analyzing the role of antioxidants in preventing food spoilage and degradation.
• Examining the effect of food processing techniques on the nutritional value of fruits and vegetables.
• Studying the chemistry of food additives and their impact on human health.
• Evaluating the role of enzymes in food digestion and processing.
• Investigating the chemical properties and functional uses of food proteins.
• Analyzing the effect of food packaging materials on the quality and safety of food products.
• Examining the chemistry of food flavorings and the impact of flavor on consumer acceptance.
• Studying the role of carbohydrates in food texture and structure.
• Investigating the chemistry of food lipids and their impact on human health.
• Analyzing the chemical properties and functional uses of food gums and emulsifiers.
• Examining the effect of processing on the flavor and aroma of food products.
• Studying the chemistry of food preservatives and their impact on food safety.
• Investigating the chemical properties and functional uses of food fibers.
• Analyzing the effect of food processing on the bioavailability of nutrients.
• Examining the chemistry of food colorants and their impact on consumer acceptance.
• Studying the role of vitamins and minerals in food and their impact on human health.
• Investigating the chemical properties and functional uses of food hydrocolloids.
• Analyzing the effect of food processing on the allergenicity of food products.
• Examining the chemistry of food sweeteners and their impact on human health.

Industrial Chemistry Research Topics

Industrial Chemistry Research Topics are as follows:

• Development of catalysts for selective hydrogenation reactions in the petrochemical industry.
• Green chemistry approaches for the synthesis of biodegradable polymers from renewable sources.
• Optimization of solvent extraction processes for the separation of rare earth elements from ores.
• Development of novel materials for energy storage applications, such as lithium-ion batteries.
• Production of biofuels from non-food sources, such as algae or waste biomass.
• Application of computational chemistry to optimize the design of new catalysts and materials.
• Design and optimization of continuous flow processes for large-scale chemical production.
• Development of new synthetic routes for the production of pharmaceutical intermediates.
• Investigation of the environmental impact of industrial processes and development of sustainable alternatives.
• Development of innovative water treatment technologies for industrial wastewater.
• Synthesis of functionalized nanoparticles for use in drug delivery and other biomedical applications.
• Optimization of processes for the production of high-performance polymers, such as polyamides or polyesters.
• Design and optimization of process control strategies for efficient and safe chemical production.
• Development of new methods for the detection and removal of heavy metal ions from industrial effluents.
• Investigation of the behavior of surfactants in complex mixtures, such as crude oil or food products.
• Development of new materials for catalytic oxidation reactions, such as the removal of volatile organic compounds from air.
• Investigation of the properties and behavior of materials under extreme conditions, such as high pressure or high temperature.
• Development of new processes for the production of chemicals from renewable resources, such as bio-based building blocks.
• Study of the kinetics and mechanism of chemical reactions in complex systems, such as multi-phase reactors.
• Optimization of the production of fine chemicals, such as flavors and fragrances, using biocatalytic processes.

Computational Chemistry Research Topics

Computational Chemistry Research Topics are as follows:

• Development and application of machine learning algorithms for predicting chemical reactions and properties.
• Investigation of the role of solvents in chemical reactions using molecular dynamics simulations.
• Modeling and simulation of protein-ligand interactions to aid drug design.
• Study of the electronic structure and reactivity of catalysts for sustainable energy production.
• Analysis of the thermodynamics and kinetics of complex chemical reactions using quantum chemistry methods.
• Exploration of the mechanism and kinetics of enzyme-catalyzed reactions using molecular dynamics simulations.
• Investigation of the properties and behavior of nanoparticles using computational modeling.
• Development of computational tools for the prediction of chemical toxicity and environmental impact.
• Study of the electronic properties of graphene and other 2D materials for applications in electronics and energy storage.
• Investigation of the mechanisms of protein folding and aggregation using molecular dynamics simulations.
• Development and optimization of computational methods for calculating thermodynamic properties of liquids and solids.
• Study of the properties of supercritical fluids for applications in separation and extraction processes.
• Development of new methods for the calculation of electron transfer rates in complex systems.
• Investigation of the electronic and mechanical properties of carbon nanotubes for applications in nanoelectronics and nanocomposites.
• Development of new approaches for modeling the interaction of biomolecules with biological membranes.
• Study of the mechanisms of charge transfer in molecular and hybrid solar cells.
• Analysis of the structural and mechanical properties of materials under extreme conditions using molecular dynamics simulations.
• Development of new approaches for the calculation of free energy differences in complex systems.
• Investigation of the reaction mechanisms of metalloenzymes using quantum mechanics/molecular mechanics (QM/MM) methods.
• Study of the properties of ionic liquids for applications in catalysis and energy storage.

Theoretical Chemistry Research Topics

Theoretical Chemistry Research Topics are as follows:

• Quantum Chemical Studies of Excited State Processes in Organic Molecules
• Theoretical Investigation of Structure and Reactivity of Metal-Organic Frameworks
• Computational Modeling of Reaction Mechanisms and Kinetics in Enzyme Catalysis
• Theoretical Investigation of Non-Covalent Interactions in Supramolecular Chemistry
• Quantum Chemical Studies of Photochemical Processes in Organic Molecules
• Theoretical Analysis of Charge Transport in Organic and Inorganic Materials
• Computational Modeling of Protein Folding and Dynamics
• Quantum Chemical Investigations of Electron Transfer Processes in Complex Systems
• Theoretical Studies of Surface Chemistry and Catalysis
• Computational Design of Novel Materials for Energy Storage Applications
• Theoretical Analysis of Chemical Bonding and Molecular Orbital Theory
• Quantum Chemical Investigations of Magnetic Properties of Complex Systems
• Computational Modeling of Biological Membranes and Transport Processes
• Theoretical Studies of Nonlinear Optical Properties of Molecules and Materials
• Quantum Chemical Studies of Spectroscopic Properties of Molecules
• Theoretical Investigations of Reaction Mechanisms in Organometallic Chemistry
• Computational Modeling of Heterogeneous Catalysis
• Quantum Chemical Studies of Excited State Dynamics in Photosynthesis
• Theoretical Analysis of Chemical Reaction Networks
• Computational Design of Nanomaterials for Biomedical Applications

Astrochemistry Research Topics

Astrochemistry Research Topics are as follows:

• Investigating the chemical composition of protoplanetary disks and its implications for planet formation
• Examining the role of magnetic fields in the formation of complex organic molecules in space
• Studying the effects of interstellar radiation on the chemical evolution of molecular clouds
• Exploring the chemistry of comets and asteroids to better understand the early solar system
• Investigating the origin and evolution of interstellar dust and its relationship to organic molecules
• Examining the formation and destruction of interstellar molecules in shocked gas
• Studying the chemical processes that occur in the atmospheres of planets and moons in our solar system
• Exploring the possibility of life on other planets through astrobiology and astrochemistry
• Investigating the chemistry of planetary nebulae and their role in the evolution of stars
• Studying the chemical properties of exoplanets and their potential habitability
• Examining the chemical reactions that occur in the interstellar medium
• Investigating the chemical composition of supernova remnants and their impact on the evolution of galaxies
• Studying the chemical composition of interstellar grains and their role in the formation of stars and planets
• Exploring the chemistry of astrocytes and their role in the evolution of galaxies
• Investigating the formation of interstellar ice and its implications for the origin of life
• Examining the chemistry of molecular clouds and its relationship to star formation
• Studying the chemical composition of the interstellar medium in different galaxies and how it varies
• Investigating the role of cosmic rays in the formation of complex organic molecules in space
• Exploring the chemical properties of interstellar filaments and their relationship to star formation
• Studying the chemistry of protostars and the role of turbulence in the formation of stars.

Geochemistry Research Topics

Geochemistry Research Topics are as follows:

• Understanding the role of mineralogical and geochemical factors on metal mobility in contaminated soils
• Investigating the sources and fate of dissolved organic matter in aquatic systems
• Exploring the geochemical signatures of ancient sedimentary rocks to reconstruct Earth’s past atmospheric conditions
• Studying the impacts of land-use change on soil organic matter content and quality
• Investigating the impact of acid mine drainage on water quality and ecosystem health
• Examining the processes controlling the behavior and fate of emerging contaminants in the environment
• Characterizing the organic matter composition of shale gas formations to better understand hydrocarbon storage and migration
• Evaluating the potential for carbon capture and storage in geologic formations
• Investigating the geochemical processes controlling the formation and evolution of ore deposits
• Studying the geochemistry of geothermal systems to better understand energy production potential and environmental impacts
• Exploring the impacts of climate change on the biogeochemistry of terrestrial ecosystems
• Investigating the geochemical cycling of nutrients in coastal marine environments
• Characterizing the isotopic composition of minerals and fluids to understand Earth’s evolution
• Developing new analytical techniques to better understand the chemistry of natural waters
• Studying the impact of anthropogenic activities on the geochemistry of urban soils
• Investigating the role of microbial processes in geochemical cycling of elements in soils and sediments
• Examining the impact of wildfires on soil and water chemistry
• Characterizing the geochemistry of mineral dust and its impact on climate and biogeochemical cycles
• Investigating the geochemical factors controlling the release and transport of contaminants from mine tailings
• Exploring the biogeochemistry of wetlands and their role in carbon sequestration and nutrient cycling.

Electrochemistry Research Topics

Electrochemistry Research Topics are as follows:

• Development of high-performance electrocatalysts for efficient electrochemical conversion of CO2 to fuels and chemicals
• Investigation of electrode-electrolyte interfaces in lithium-ion batteries for enhanced battery performance and durability
• Design and synthesis of novel electrolytes for high-energy-density and stable lithium-sulfur batteries
• Development of advanced electrochemical sensors for the detection of trace-levels of analytes in biological and environmental samples
• Analysis of the electrochemical behavior of new materials and their electrocatalytic properties in fuel cells
• Study of the kinetics of electrochemical reactions and their effect on the efficiency and selectivity of electrochemical processes
• Development of novel strategies for the electrochemical synthesis of value-added chemicals from biomass and waste materials
• Analysis of the electrochemical properties of metal-organic frameworks (MOFs) for energy storage and conversion applications
• Investigation of the electrochemical degradation mechanisms of polymer electrolyte membranes in fuel cells
• Study of the electrochemical properties of 2D materials and their applications in energy storage and conversion devices
• Development of efficient electrochemical systems for desalination and water treatment applications
• Investigation of the electrochemical properties of metal-oxide nanoparticles for energy storage and conversion applications
• Analysis of the electrochemical behavior of redox-active organic molecules and their application in energy storage and conversion devices
• Study of the electrochemical behavior of metal-organic frameworks (MOFs) for the catalytic conversion of CO2 to value-added chemicals
• Development of novel electrode materials for electrochemical capacitors with high energy density and fast charge/discharge rates
• Investigation of the electrochemical properties of perovskite materials for energy storage and conversion applications
• Study of the electrochemical behavior of enzymes and their application in bioelectrochemical systems
• Development of advanced electrochemical techniques for the characterization of interfacial processes in electrochemical systems
• Analysis of the electrochemical behavior of nanocarbons and their application in electrochemical energy storage devices
• Investigation of the electrochemical properties of ionic liquids for energy storage and conversion applications.

Surface Chemistry Research Topics

Surface Chemistry Research Topics are as follows:

• Surface modification of nanoparticles for enhanced catalytic activity
• Investigating the effect of surface roughness on the wetting behavior of materials
• Development of new materials for solar cell applications through surface chemistry techniques
• Surface chemistry of graphene and its applications in electronic devices
• Surface functionalization of biomaterials for biomedical applications
• Characterization of surface defects and their effect on material properties
• Surface modification of carbon nanotubes for energy storage applications
• Developing surface coatings for corrosion protection of metals
• Synthesis of self-assembled monolayers on surfaces for sensor applications
• Surface chemistry of metal-organic frameworks for gas storage and separation
• Investigating the role of surface charge in protein adsorption
• Developing surfaces with superhydrophobic or superoleophobic properties for self-cleaning applications
• Surface functionalization of nanoparticles for drug delivery applications
• Surface chemistry of semiconductors and its effect on photovoltaic properties
• Development of surface-enhanced Raman scattering (SERS) substrates for trace analyte detection
• Surface functionalization of graphene oxide for water purification applications
• Investigating the role of surface tension in emulsion formation and stabilization
• Surface modification of membranes for water desalination and purification
• Synthesis and characterization of metal nanoparticles for catalytic applications
• Development of surfaces with controlled wettability for microfluidic applications.

Atmospheric Chemistry Research Topics

Atmospheric Chemistry Research Topics are as follows:

• The impact of wildfires on atmospheric chemistry
• The role of aerosols in atmospheric chemistry
• The chemistry and physics of ozone depletion in the stratosphere
• The chemistry and dynamics of the upper atmosphere
• The impact of anthropogenic emissions on atmospheric chemistry
• The role of clouds in atmospheric chemistry
• The chemistry of atmospheric particulate matter
• The impact of nitrogen oxides on atmospheric chemistry and air quality
• The effects of climate change on atmospheric chemistry
• The impact of atmospheric chemistry on climate change
• The chemistry and physics of atmospheric mercury cycling
• The impact of volcanic eruptions on atmospheric chemistry
• The chemistry and physics of acid rain formation and effects
• The role of halogen chemistry in the atmosphere
• The chemistry of atmospheric radicals and their impact on air quality and health
• The impact of urbanization on atmospheric chemistry
• The chemistry and physics of stratospheric polar vortex dynamics
• The role of natural sources (e.g. ocean, plants) in atmospheric chemistry
• The impact of atmospheric chemistry on the biosphere
• The chemistry and dynamics of the ozone hole over Antarctica.

Photochemistry Research Topics

Photochemistry Research Topics are as follows:

• Investigating the mechanisms of photoinduced electron transfer reactions in organic photovoltaic materials.
• Developing novel photoredox catalysts for photochemical reactions.
• Understanding the effects of light on DNA and RNA stability and replication.
• Studying the photochemistry of atmospheric pollutants and their impact on air quality.
• Designing new photoresponsive materials for advanced photonic and electronic devices.
• Exploring the photochemistry of metalloporphyrins for potential applications in catalysis.
• Investigating the photochemistry of transition metal complexes and their use as photodynamic therapy agents.
• Developing new photocatalytic systems for sustainable energy production.
• Studying the photochemistry of natural products and their potential pharmaceutical applications.
• Investigating the role of light in the formation and degradation of environmental contaminants.
• Designing new photochromic materials for smart windows and displays.
• Exploring the photochemistry of carbon nanomaterials for energy storage and conversion.
• Developing new light-driven molecular machines for nanotechnology applications.
• Investigating the photochemistry of organic dyes for potential applications in dye-sensitized solar cells.
• Studying the effects of light on the behavior of biological macromolecules.
• Designing new photoresponsive hydrogels for drug delivery applications.
• Exploring the photochemistry of semiconductor nanoparticles for potential applications in quantum computing.
• Investigating the mechanisms of photochemical reactions in ionic liquids.
• Developing new photonic sensors for chemical and biological detection.
• Studying the photochemistry of transition metal complexes for potential applications in water splitting and hydrogen production.

About the author

Muhammad Hassan

Researcher, Academic Writer, Web developer

You may also like

200+ Funny Research Topics

500+ Sports Research Topics

300+ American History Research Paper Topics

500+ Cyber Security Research Topics

500+ Environmental Research Topics

500+ Economics Research Topics

Subscribe or renew today

Every print subscription comes with full digital access

Science News

A new method of making diamonds doesn’t require extreme pressure 

Lab-grown diamonds can form at atmospheric pressure in a liquid of gallium, iron, nickel and silicon.

How a sugar acid crucial for life could have formed in interstellar clouds

Protein whisperer Oluwatoyin Asojo fights neglected diseases

Sign Up For the Latest from Science News

Headlines and summaries of the latest Science News articles, delivered to your inbox

Thank you for signing up!

There was a problem signing you up.

More Stories in Chemistry

These are the chemicals that give teens pungent body odor

Steroids and high levels of carboxylic acids in teenagers’ body odor give off a mix of pleasant and acrid scents.

The smallest known molecular knot is made of just 54 atoms

Chemists are still trying to figure out why this combination of gold, phosphorus, oxygen and carbon atoms resulted in a molecular knot in the first place.

Here’s how tardigrades go into suspended animation

A new study offers more clues about the role of oxidation in signaling transitions between alive and mostly dead in tardigrades.

Capturing methane from the air would slow global warming. Can it be done?

Removing methane from the atmosphere requires different technology from removing carbon dioxide. Scientists are taking on the challenge.

‘Most Delicious Poison’ explores how toxins rule our world

In his debut book, Noah Whiteman tours through chemistry, evolution and world history to understand toxins and how we’ve come to use them.

Light, not just heat, might spur water to evaporate

In experiments, light shining on water as much as doubled the evaporation rate expected from heat alone, hinting at a never-before-seen effect.

Salty sweat helps one desert plant stay hydrated

The Athel tamarisk excretes excess salt through its leaves. The buildup of salt crystals pulls water directly from the air, a study reports.

The development of quantum dots wins the 2023 Nobel prize in chemistry

Moungi Bawendi, Louis Brus and Alexei Ekimov split the prize for their work in creating nanoparticles whose properties depend on their size.

50 years ago, the quest for superheavy elements was just getting started

In the 1970s, scientists were on the hunt for superheavy elements. They’ve since found more than a dozen and are searching for more.

Subscribers, enter your e-mail address for full access to the Science News archives and digital editions.

Not a subscriber? Become one now .

• April 26, 2024 | Puzzling Scientists for Over 50 Years – A “Holy Grail” Chemical Mystery Has Been Solved
• April 26, 2024 | NASA Astronauts Land in Florida, Ready for Historic Boeing Starliner Test Flight
• April 26, 2024 | Cosmonauts Complete Spacewalk to Install Communication and Corrosion Equipment
• April 25, 2024 | Compact Quantum Light Processing: Time-Bending Optical Computing Breakthrough
• April 25, 2024 | New Research Links Chronic Pain to Socioeconomic Background

Chemistry News

SciTechDaily features the latest chemistry news and recent research articles from leading universities and institutes from around the world. Here, we delve into the ever-evolving realm of molecules, elements, and reactions, bringing you up-to-date insights from renowned scientists and researchers.

Read interesting chemistry news and breakthrough research on related topics like Biochemistry , Chemical Engineering , Materials Science , Nanoparticles , and Polymers .

Our comprehensive coverage spans the spectrum of chemistry, from organic and inorganic chemistry to biochemistry, analytical chemistry, and beyond. Stay informed about groundbreaking advancements, innovative techniques, and novel applications shaping the future of chemistry and its impact on our everyday lives. Discover, learn, and fuel your passion for chemistry with SciTechDaily.

Chemistry April 26, 2024

Puzzling Scientists for Over 50 Years – A “Holy Grail” Chemical Mystery Has Been Solved

A mystery that has puzzled the scientific community for over 50 years has finally been solved. A team from Linköping University, Sweden, and Helmholtz Munich…

Revolutionizing Renewable Energy: Innovative Salt Battery Efficiently Harvests Osmotic Power

Revolutionizing Plastics: Safer, Greener LDPE Alternatives Unveiled

Extracting Pure Gold: Turning Electronic Waste Into Treasure

Unlocking the Secrets of Space Chemistry With Cold Coulomb Crystals

Trash To Treasure – Chemists Turn Metal Waste Into Hydrogen Catalyst

Organic Catalyst Discovery Could Reduce the Cost of Fuel Cells

“Neutronic Molecules” – Neutrons Meet Quantum Dots in Groundbreaking MIT Discovery

A Molecular Moonlander: PPh3’s Movement Challenges Conventional Science

Chemistry April 12, 2024

Researchers Develop Simple Way To Harvest More “Blue Energy” From Waves

As any surfer will tell you, waves pack a powerful punch. We’re now making strides toward harnessing the ocean’s relentless movements for energy, thanks to…

Chemistry April 11, 2024

Powering the Future: Unbiased PEC Cells Achieve Unprecedented Efficiency

Over the last decade, the photoelectrochemical (PEC) process for overall water-splitting (OWS) has seen comprehensive development, particularly in the areas of new catalysts, methods of…

Chemistry April 10, 2024

The Power of Waste: A New Innovative Approach To Improve the Energy Efficiency of Carbon Conversion

Scientists at McGill University have developed a novel method to enhance the energy efficiency of carbon conversion, utilizing waste material from pulp and paper production….

The Future of Solar Cells and More – Japanese Chemists Develop Glowing, Self-Healing Material

A research team at the RIKEN Center for Sustainable Resource Science (CSRS) has succeeded in developing a self-healing material that is also capable of emitting…

Chemistry April 9, 2024

Microbial Magic: Genetic Tweaks Unlock Superior Bioplastics

Engineered bacteria can produce a plastic modifier that makes renewably sourced plastic more processable, more fracture-resistant and highly biodegradable even in sea water. The Kobe…

Revolutionizing Clean Energy: Transforming Rare Earth Element Extraction

Scientists have developed an innovative method to separate lanthanides, crucial for clean energy technologies, by combining substances that attract either lighter or heavier elements. This…

Chemistry April 7, 2024

Japanese Scientists Unveil Game-Changing Material for Magnesium Batteries

Scientists at Tohoku University have achieved a significant breakthrough in battery technology by creating a new cathode material for rechargeable magnesium batteries (RMBs). This material…

Decoding the Origin of Life: Scientists Solve Early Earth RNA Puzzle

Recent research illustrates how RNA molecules’ chemical characteristics might have played a crucial role in the development of complex life forms. How did complex life…

Chemistry April 6, 2024

From Chaos to Life: Unraveling Nature’s Ancient Molecular Kitchen

Life is complicated. What is true for our everyday existence also holds for the many complex processes that take place inside cells. Proteins are continuously…

This website uses cookies to improve your user experience. By continuing to use the site, you are accepting our use of cookies. Read the ACS privacy policy.

• ACS Publications

21 Cutting-Edge Chemistry Topics

• Jul 31, 2020
• 14 min read

ACS Publications regularly produces collections of the most important chemistry research topics. These Virtual Collections of the most important chemistry research topics bring together the most important ideas in the field in a variety of ways, including Special Issues and ACS Selects from across the portfolio journals. These collections reflect the most important chemistry research […]

ACS Publications regularly produces collections of the most important chemistry research topics. These Virtual Collections of the most important chemistry research topics bring together the most important ideas in the field in a variety of ways, including Special Issues and ACS Selects from across the portfolio journals. These collections reflect the most important chemistry research topics of current scientific interest and are designed for experienced investigators and educators alike.

Browse 21 of the most important, engaging topics in chemists with Virtual Collections released by ACS Publications journals in Q2 2020:

David N. Beratan Festschrift

David Beratan’s unique style of doing science has had a broad and deep impact on chemistry, biochemistry, and biophysics. He has developed theories with an eye toward influencing the design and interpretation of key experiments, and his impact has been tremendous. David’s insights and predictive models have opened up entirely new research directions to experimental inquiry: tunneling pathways, inverse molecular design, optimization of polarizability response through ground-state polarization, flickering resonance, and chiral imprinting are all examples of concepts that he has pioneered that have guided experimental designs and advances for decades. ***

First Accounts

Early-career scientists have some of the freshest ideas and are instrumental in pushing the frontiers of chemistry and related disciplines. Recognizing this, we have initiated the first in an annual series of virtual issues highlighting the publications in Accounts of Chemical Research over the past year that are authored by early-stage scientists: First Accounts. In addition to featuring early career researchers, each Account in this collection is the first article the corresponding author has published in Accounts of Chemical Research as a principal investigator.

First Accounts are also first-hand accounts—our junior faculty and newest researchers in industry and institutes are the most engaged in experimental design and execution in the laboratory, and we see this reflected in the writing from younger authors. In most cases, they have staked their careers on the success of the research program described in their Account, and justifiably, that passion for molecular design, mechanistic inquiry, and structural evidence comes through in their writing. ***

Sustainability

To promote the positive role that chemistry plays in the world, ACS established the Chemists Celebrate Earth Week (CCEW) which will occur April 19-25, 2020. This year’s theme is “Protecting Our Planet through Chemistry”, with a focus on sustainability. ***

Complex Organic Molecules in Star-Forming Regions

This Virtual Special Issue is concerned mainly with a class of interstellar molecules that strongly resemble organic molecules present in the terrestrial organic laboratory. These molecules, known as “complex organic molecules”, a term abbreviated either as COMs or iCOMs, the “I” standing for “interstellar” since these molecules, containing from 6-13 atoms, are hardly complex when compared with the much larger molecules found on Earth. The COMs, which include simple alcohols, esters, nitriles, and ethers, have been observed extensively by radio astronomy. The wealth of material in this Virtual Special Issue concerning interstellar complex organic molecules should provide the reader with a comprehensive introduction to this burgeoning area of astrochemistry. If the 50-year history of astrochemistry is any guide, however, research in the future is likely to change some of the conclusions reached here. Nevertheless, the future work will be based on the solid foundation reported. ***

New Advances in Organic Aerosol Chemistry

This virtual issue is a collection of exciting new advances in organic aerosol chemistry. The manuscripts fall into four broad and interconnected categories: (1) novel insights into secondary organic aerosol (SOA) formation, (2) the impact of organics on aerosol physical properties relevant for climate, (3) organics and the aerosol-cloud life cycle, and (4) field observations of organic aerosols and their transformations. Collectively, the manuscripts in this virtual issue represent the next generation of ideas and techniques in this field. Further research, enabled by recent advances in aerosol technology and collaborative and inclusive research culture, will be needed to tackle the urgent challenges in global air pollution and climate that we face today. ***

Area Selective Deposition: From Materials Chemistry to Nanofabrication

Right around 2014, as the minimum feature size of electronic devices approached 10 nm, nanofabrication needed a break-through technology to enable precise fabrication in 3D structures within the few nanometer scale. Area selective atomic layer deposition (AS-ALD) was recognized as having many advantages for this challenge because it is a bottom-up patterning approach with high conformality in 3D structures. The purpose of this virtual issue is to compile some of the recent, scientifically innovative papers in AS-ALD research published in Chemistry of Materials and other ACS journals for readers who are interested in this research field. Although the papers in this issue are focused on those published recently, we also include a few older published papers to provide some context about the main research history. ***

20th Anniversary of Aggregation-Induced Emission

2020 marks the 20th anniversary of the concept of aggregation-induced emission (AIE). Since the concept was first coined in 2001, it changes the way people think about chromophore aggregation and provides a broad platform for the design and development of new luminescent materials in practically useful solid state. AIE and the related interdisciplinary research have greatly promoted the continuous innovation and rapid development of chemistry, materials and medicine, which lay an important physical and theoretical foundation for related fields with substantial global impact. The collection of 30 recently published articles from these ACS journals highlights the dynamic and vibrant AIE research. This Virtual Issue will serve as valuable resources for both well-established and early career researchers to learn more about AIE.

Remembering the Contributions and Life of Professor Joel Bernstein

Professor Joel Bernstein (1941–2019) inspired many of us with his insatiable enthusiasm for science and teaching and his passion for the organic solid state. Joel will be remembered for his humanity, compassion, wisdom, scientific depth and breadth, and an unsurpassed passion for history, especially when interwoven with science. He was, truly, polymorphic. This Virtual Special Issue of Crystal Growth & Design is intended to celebrate and commemorate his contributions to the field. ***

Melbourne – Australia’s Science City

Melbourne is Australia’s second largest city and fastest growing metropolis with around 4.5 million inhabitants. It is also the Australian biomedical and materials science hub. This virtual issue of ACS Nano celebrates recent research in nanoscience and nanotechnology emanating from various institutes within the city of Melbourne: University of Melbourne, Monash University, RMIT University, Swinburne University, the Melbourne Centre for Nanofabrication, and CSIRO. ***

Toward Chemistry in Real Space and Real Time

This Virtual Special Issue bears the title of the symposium held during the National Meeting of the American Chemical Society Fall 2019 National Meeting in San Diego, CA, marking the sunset of the eponymous Center for Chemistry at the Space-Time Limit. This National Science Foundation (NSF) Center for Chemical Innovation was founded with the vision to capture motions of individual molecules in real space and time, ultimately, to reach the joint Å-fs scale resolution necessary to visualize chemistry in the act. This VSI serves a collection of manuscripts by participants that capture the topics covered at the CaSTL sunset symposium. ***

Giants in Sensing: A Virtual Issue to Celebrate Five Years of ACS Sensors

As ACS Sensors celebrates its first five years of publication, we want to take this opportunity to honor people who have been central in shaping the field. To most scientists, chemical and biological sensing is a thoroughly modern discipline. It is unashamedly interdisciplinary, marrying fundamental insights and the foundations of analytical chemistry, state of the art materials science, bioengineering, electrochemistry, optics, biology, clinical and environmental chemistry. It addresses important measurement science challenges that face us today. This is what motivates many of us to contribute to this important field. Together with Analytical Chemistry and the Journal of the American Chemical Society , we present a virtual issue on Giants in Sensing featuring some fifty articles from influential sensing researchers who have contributed to any of these journals in the past five years. Please go through the list, read these excellent articles, and be sure to remember their names and those that came before when you write your next publication. It is humbling to know that we are all standing on the shoulders of giants. ***

Natural Products: Isolation, Total Synthesis, Structure-Activity Relationships, and More

Chemists are known for their ability to design and create molecules and materials—it is at the heart of what we do. Many of our ideas originate with the ultimate molecular designer and synthetic engineer, Nature, which has found an elegant way over time to create the necessary molecules of life or ones that participate in life cycles. Much of the new chemistry involving these natural products ends up on the pages of Organic Letters and The Journal of Organic Chemistry each year, pieced together through total synthesis to guide the way toward developing new and improved medicines, agricultural chemicals, biocatalysts, and more.

In this Virtual Issue, we feature 40 leading articles on natural products chemistry, selected by Organic Letters Editor-in-Chief Erick M. Carreira and The Journal of Organic Chemistry Editor-in-Chief Scott J. Miller from among the more than 250 articles on the topic published in the ACS core organic journals during 2019. ***

Quantum Dots and their Applications: What Lies Ahead?

It has been many years since the first works on the reduced dimensionality of semiconductors, which led to the concept of ‘artificial atoms’, or quantum dots (QDs). These semiconductor nanocrystals, with nanometer-sized diameters, exhibit quantum size effects in their optical and electronic properties. In particular, tunable and efficient photoluminescence (PL), with narrow emission and photochemical stability, as well as core-shell structures are commonly achieved today for many quantum dot materials systems. As a consequence, quantum dots have been incorporated as active elements in a wide variety of devices and applications, such as light-emitting diodes and display applications, photovoltaics, photoconductors and photodetectors, biomedical and environmental applications and catalysis applications. Many of these applications are now commercially-available and incorporated into our daily life, such as the case of quantum-dot-based displays. Despite being now part of mature technologies, quantum dot synthesis, characterization, and applications still constitute a highly active field of investigation. In light of various new development in applications of quantum dots, it is our pleasure to announce a “virtual issue” on quantum dots and their applications for ACS Applied Nano Materials . ***

Laboratory Learning

The Journal of Chemical Education has published many widely cited articles about learning in the chemistry laboratory. Laboratory teaching continues to evolve and face new challenges in today’s world. To help share the broad approaches to laboratory education, the journal has provided a collective resource of articles on laboratory learning and understanding, inquiry methods, student preparedness, assessing the lab, and faculty goals and professional development for laboratory teaching. We hope your find these articles as a useful resource increasing your knowledge in laboratory learning. ***

Challenges and Opportunities in Designing Perovskite Nanocrystal Heterostructures

Since the first report of CsPbBr3 nanocrystal synthesis by the hot-injection five years ago, we have seen phenomenal growth in research efforts to understand the photodynamics, luminescent properties, and stabilization of different phases of perovskite materials. We envision the possibility of designing perovskite nanocrystal heterostructures in combinations with other perovskites, metal oxides and chalcogenides, and precious metals and 2D materials. This virtual issue highlights some of the key findings published in ACS Applied Materials and Interfaces, ACS Energy Letters, ACS Nano, Chemistry of Materials, Journal of American Chemical Society, Nano Letters, and Journal of Physical Chemistry C . ***

International Symposium on Molecular Spectroscopy

The collection of papers in this virtual special issue of the Journal of Physical Chemistry A are representative of the work disseminated over the last decade at the International Symposium on Molecular Spectroscopy (ISMS), which is on the verge of its 75th anniversary. The ISMS was founded in 1946 and was held on campus at The Ohio State University for 68 consecutive years, where after it moved to the University of Illinois Urbana-Champaign. Historically, the emphasis of the ISMS has been the characterization of the structure, dynamics, and spectroscopy of molecular systems, including complexes and clusters. The fundamental spectroscopic techniques developed by the participants of ISMS have been applied over the years to an ever more precise understanding of the chemistry and physics of aqueous environments, combustion, the interstellar medium, and planetary atmospheres, to name a few of the more popular areas of discussion at the symposium. This research, in both the gas and condensed phases, spans the subject areas of JPC A . ***

3D Printing of Polymers

The distributive manufacturing enabled by 3D printing has been on display in the response to shortages in critical medical resources for the response to the COVID-19 epidemic. In almost all cases, these 3D printed parts have been polymers and have been instrumental in providing a stopgap to logistical challenges in obtaining critical components. These have included, amongst many other examples, engineered solutions to limited number of ventilators through 3D printing of valves for ventilators, parts to transform snorkeling masks into continuous positive airway pressure (CPAP) devices, and repurposing of existing medical equipment to meet demands for treating patients. The timely delivery of these 3D printed plastic components has been enabled by the advances in 3D printing over the past decades. In light of their acute significance in this global health crisis, it is our pleasure to announce a “virtual issue” on the 3D printing of polymers for ACS Applied Polymer Materials .

New Tools and Methods in Physical Chemistry Research

This spring marks the second anniversary of the introduction of a section in The Journal of Physical Chemistry A highlighting work in the development of New Tools and Methods in Experiment and Theory. Work published in this section of J. Phys. Chem. A spans the full scope of physical chemistry research that is published in the three parts of the Journal. In the two years since this section was introduced, we have published more than 200 articles. In this collection of twenty-five articles, we highlight representative examples of the exciting work in the development of new tools and methods, which has been published in The Journal over the past two years. ***

Recent Highlights on Interfaces from China

This Langmuir virtual issue contains a collection of carefully selected articles which showcase very recent studies on interfaces from China. The authors with science and engineering backgrounds are from national and state key laboratories, academic institutes as well as universities located at various parts of China. We hope that you’ll enjoy reading this sample collection of Langmuir publications for the recent exciting work on nanomaterials and interfaces authored by Chinese scientists! ***

Virus Detection

In this virtual issue, we highlight 23 papers centered on the development of molecular tests for viruses. The type of work these researchers were doing was no less important then, than it is now. Current events have just brought the importance of their work into focus. We feel the papers in this virtual issue serve as a benchmark for the types of innovation the journals Analytical Chemistry and ACS Sensors are looking for. The papers we selected are just a subset of the many wonderful, innovative papers on infection detection we have published and represent the incredible work being done around the globe in detection science that will help keep us safe. When we read the papers, they give us hope that we will be far better equipped to deal with any future potential pandemics. We thank these scientists for their research. ***

A New Era of Metal-Organic Framework Nanomaterials and Applications

Want the latest stories delivered to your inbox each month?

Students & Educators  —Menu

• Educational Resources
• Educators & Faculty
• College Planning
• ACS ChemClub
• Project SEED
• U.S. National Chemistry Olympiad
• Student Chapters
• ACS Meeting Information
• Undergraduate Research
• Internships, Summer Jobs & Coops
• Study Abroad Programs
• Finding a Mentor
• Two Year/Community College Students
• Social Distancing Socials

Planning for Graduate School

• Grants & Fellowships
• Career Planning
• International Students
• Planning for Graduate Work in Chemistry
• ACS Bridge Project
• Graduate Student Organizations (GSOs)
• Schedule-at-a-Glance
• Standards & Guidelines
• Explore Chemistry
• Science Outreach
• Publications
• ACS Student Communities
• You are here:
• American Chemical Society
• Students & Educators
• Undergraduate
• Undergraduate Research Guide

Undergraduate Research in Chemistry Guide

Research is the pursuit of new knowledge through the process of discovery. Scientific research involves diligent inquiry and systematic observation of phenomena. Most scientific research projects involve experimentation, often requiring testing the effect of changing conditions on the results. The conditions under which specific observations are made must be carefully controlled, and records must be meticulously maintained. This ensures that observations and results can be are reproduced. Scientific research can be basic (fundamental) or applied. What is the difference? The National Science Foundation uses the following definitions in its resource surveys:

• Basic research The objective of basic research is to gain more comprehensive knowledge or understanding of the subject under study, without specific applications in mind. In industry, basic research is defined as research that advances scientific knowledge but does not have specific immediate commercial objectives, although it may be in fields of present or potential commercial interest.
• Applied research Applied research is aimed at gaining knowledge or understanding to determine the means by which a specific, recognized need may be met. In industry, applied research includes investigations oriented to discovering new scientific knowledge that has specific commercial objectives with respect to products, processes, or services.

Get on the path to graduate school with our comprehensive guide to selecting an institution and preparing for graduate studies.

What is research at the undergraduate level?

At the undergraduate level, research is self-directed work under the guidance and supervision of a mentor/advisor ― usually a university professor. A gradual transition towards independence is encouraged as a student gains confidence and is able to work with minor supervision. Students normally participate in an ongoing research project and investigate phenomena of interest to them and their advisor. In the chemical sciences, the range of research areas is quite broad. A few groups maintain their research area within a single classical field of analytical, inorganic, organic, physical, chemical education or theoretical chemistry. More commonly, research groups today are interdisciplinary, crossing boundaries across fields and across other disciplines, such as physics, biology, materials science, engineering and medicine.

What are the benefits of being involved in undergraduate research?

There are many benefits to undergraduate research, but the most important are:

• Learning, learning, learning. Most chemists learn by working in a laboratory setting. Information learned in the classroom is more clearly understood and it is more easily remembered once it has been put into practice. This knowledge expands through experience and further reading. From the learning standpoint, research is an extremely productive cycle.
• Experiencing chemistry in a real world setting. The equipment, instrumentation and materials used in research labs are generally more sophisticated, advanced, and of far better quality than those used in lab courses
• Getting the excitement of discovery. If science is truly your vocation, regardless of any negative results, the moment of discovery will be truly exhilarating. Your results are exclusive. No one has ever seen them before.
• Preparing for graduate school. A graduate degree in a chemistry-related science is mostly a research degree. Undergraduate research will not only give you an excellent foundation, but working alongside graduate students and post-doctorates will provide you with a unique opportunity to learn what it will be like.

Is undergraduate research required for graduation?

Many chemistry programs now require undergraduate research for graduation. There are plenty of opportunities for undergraduate students to get involved in research, either during the academic year, summer, or both. If your home institution is not research intensive, you may find opportunities at other institutions, government labs, and industries.

What will I learn by participating in an undergraduate research program?

Conducting a research project involves a series of steps that start at the inquiry level and end in a report. In the process, you learn to:

• Conduct scientific literature searches
• Read, interpret and extract information from journal articles relevant to the project
• Design experimental procedures to obtain data and/or products of interest
• Operate instruments and implement laboratory techniques not usually available in laboratories associated with course work
• Interpret results, reach conclusions, and generate new ideas based on results
• Interact professionally (and socially) with students and professors within the research group, department and school as well as others from different schools, countries, cultures and backgrounds
• Communicate results orally and in writing to other peers, mentors, faculty advisors, and members of the scientific community at large via the following informal group meeting presentations, reports to mentor/advisor, poster presentations at college-wide, regional, national or international meetings; formal oral presentations at scientific meetings; or journal articles prepared for publication

When should I get involved in undergraduate research?

Chemistry is an experimental science. We recommended that you get involved in research as early in your college life as possible. Ample undergraduate research experience gives you an edge in the eyes of potential employers and graduate programs.

While most mentors prefer to accept students in their research labs once they have developed some basic lab skills through general and organic lab courses, some institutions have programs that involve students in research projects the summer prior to their freshman year. Others even involve senior high school students in summer research programs. Ask your academic/departmental advisor about the options available to you.

How much time should I allocate to research?

The quick answer is as much as possible without jeopardizing your course work. The rule of thumb is to spend 3 to 4 hours working in the lab for every credit hour in which you enroll. However, depending on the project, some progress can be achieved in just 3-4 hours of research/week. Most advisors would recommend 8-10 hours/week.

Depending on your project, a few of those hours may be of intense work and the rest may be spent simply monitoring the progress of a reaction or an instrumental analysis. Many research groups work on weekends. Saturdays are excellent days for long, uninterrupted periods of lab work.

How do I select an advisor?

This is probably the most important step in getting involved in undergraduate research. The best approach is multifaceted. Get informed about research areas and projects available in your department, which are usually posted on your departmental website under each professor’s name.

Talk to other students who are already involved in research. If your school has an ACS Student Chapter , make a point to talk to the chapter’s members. Ask your current chemistry professor and lab instructor for advice. They can usually guide you in the right direction. If a particular research area catches your interest, make an appointment with the corresponding professor.

Let the professor know that you are considering getting involved in research, you have read a bit about her/his research program, and that you would like to find out more. Professors understand that students are not experts in the field, and they will explain their research at a level that you will be able to follow. Here are some recommended questions to ask when you meet with this advisor:

• Is there a project(s) within her/his research program suitable for an undergraduate student?
• Does she/he have a position/space in the lab for you?
• If you were to work in her/his lab, would you be supervised directly by her/him or by a graduate student? If it is a graduate student, make a point of meeting with the student and other members of the research group. Determine if their schedule matches yours. A night owl may not be able to work effectively with a morning person.
• Does she/he have funding to support the project? Unfunded projects may indicate that there may not be enough resources in the lab to carry out the project to completion. It may also be an indication that funding agencies/peers do not consider this work sufficiently important enough for funding support. Of course there are exceptions. For example, a newly hired assistant professor may not have external funding yet, but he/she may have received “start-up funds” from the university and certainly has the vote of confidence of the rest of the faculty. Otherwise he/she would not have been hired. Another classical exception is computational chemistry research, for which mostly fast computers are necessary and therefore external funding is needed to support research assistants and computer equipment only. No chemicals, glassware, or instrumentation will be found in a computational chemistry lab.
• How many of his/her articles got published in the last two or three years? When prior work has been published, it is a good indicator that the research is considered worthwhile by the scientific community that reviews articles for publication. Ask for printed references. Number of publications in reputable refereed journals (for example ACS journals) is an excellent indicator of the reputation of the researcher and the quality of his/her work.

Here is one last piece of advice: If the project really excites you and you get satisfactory answers to all your questions, make sure that you and the advisor will get along and that you will enjoy working with him/her and other members of the research group.

Remember that this advisor may be writing recommendation letters on your behalf to future employers, graduate schools, etc., so you want to leave a good impression. To do this, you should understand that the research must move forward and that if you become part of a research team, you should do your best to achieve this goal. At the same time, your advisor should understand your obligations to your course work and provide you with a degree of flexibility.

Ultimately, it is your responsibility to do your best on both course work and research. Make sure that the advisor is committed to supervising you as much as you are committed to doing the required work and putting in the necessary/agreed upon hours.

What are some potential challenges?

• Time management . Each project is unique, and it will be up to you and your supervisor to decide when to be in the lab and how to best utilize the time available to move the project forward.
• Different approaches and styles . Not everyone is as clean and respectful of the equipment of others as you are. Not everyone is as punctual as you are. Not everyone follows safety procedures as diligently as you do. Some groups have established protocols for keeping the lab and equipment clean, for borrowing equipment from other members, for handling common equipment, for research meetings, for specific safety procedures, etc. Part of learning to work in a team is to avoid unnecessary conflict while establishing your ground to doing your work efficiently.
• “The project does not work.” This is a statement that advisors commonly hear from students. Although projects are generally very well conceived, and it is people that make projects work, the nature of research is such that it requires patience, perseverance, critical thinking, and on many occasions, a change in direction. Thoroughness, attention to detail, and comprehensive notes are crucial when reporting the progress of a project.

Be informed, attentive, analytical, and objective. Read all the background information. Read user manuals for instruments and equipment. In many instances the reason for failure may be related to dirty equipment, contaminated reagents, improperly set instruments, poorly chosen conditions, lack of thoroughness, and/or lack of resourcefulness. Repeating a procedure while changing one parameter may work sometimes, while repeating the procedure multiple times without systematic changes and observations probably will not.

When reporting failures or problems, make sure that you have all details at hand. Be thorough in you assessment. Then ask questions. Advisors usually have sufficient experience to detect errors in procedures and are able to lead you in the right direction when the student is able to provide all the necessary details. They also have enough experience to know when to change directions. Many times one result may be unexpected, but it may be interesting enough to lead the investigation into a totally different avenue. Communicate with your advisor/mentor often.

Are there places other than my institution where I can conduct research?

Absolutely! Your school may be close to other universities, government labs and/or industries that offer part-time research opportunities during the academic year. There may also be summer opportunities in these institutions as well as in REU sites (see next question).

Contact your chemistry department advisor first. He/she may have some information readily available for you. You can also contact nearby universities, local industries and government labs directly or through the career center at your school. You can also find listings through ACS resources:

• Research Opportunities (US only)
• International Research Opportunities
• Internships and Summer Jobs

What are Research Experiences for Undergraduates (REU) sites? When should I apply for a position in one of them?

REU is a program established by the National Science Foundation (NSF) to support active research participation by undergraduate students at host institutions in the United States or abroad. An REU site may offer projects within a single department/discipline or it may have projects that are inter-departmental and interdisciplinary. There are currently over 70 domestic and approximately 5 international REU sites with a chemistry theme. Sites consist of 10-12 students each, although there are larger sites that supplement NSF funding with other sources. Students receive stipends and, in most cases, assistance with housing and travel.

Most REU sites invite rising juniors and rising seniors to participate in research during the summer. Experience in research is not required to apply, except for international sites where at least one semester or summer of prior research experience is recommended. Applications usually open around November or December for participation during the following summer. Undergraduate students supported with NSF funds must be citizens or permanent residents of the United States or its possessions. Some REU sites with supplementary funds from other sources may accept international students that are enrolled at US institutions.

• Get more information about REU sites

How do I prepare a scientific research poster?

Here are some links to sites with very useful information and samples.

• How to Prepare a Proper Scientific Paper or Poster
• Creating Effective Poster Presentations
• Designing Effective Poster Presentations

Research and Internship Opportunities

• Internships and Fellowships Find internships, fellowships, and cooperative education opportunities.
• SCI Scholars Internship Program Industrial internships for chemistry and chemical engineering undergraduates.
• ACS International Center Fellowships, scholarships, and research opportunities around the globe

Accept & Close The ACS takes your privacy seriously as it relates to cookies. We use cookies to remember users, better understand ways to serve them, improve our value proposition, and optimize their experience. Learn more about managing your cookies at Cookies Policy .

1155 Sixteenth Street, NW, Washington, DC 20036, USA |  service@acs.org  | 1-800-333-9511 (US and Canada) | 614-447-3776 (outside North America)

• Terms of Use
• Accessibility

Copyright © 2024 American Chemical Society

201+ Chemistry Project Topics [Updated]

Chemistry, often hailed as the “central science,” plays a pivotal role in understanding the world around us. From the composition of substances to the reactions that transform them, chemistry influences nearly every aspect of our lives. One fascinating way to delve deeper into this field is through chemistry projects. These projects offer a hands-on approach to learning, allowing students and enthusiasts alike to explore various concepts and phenomena. In this blog, we’ll journey through a diverse array of chemistry project topics, offering insights into each area’s significance and potential for exploration.

How To Select Relevant Chemistry Project Topics?

Table of Contents

Selecting relevant chemistry project topics requires careful consideration of several factors to ensure that the chosen topic aligns with your interests, goals, and resources. Here’s a step-by-step guide to help you select the most suitable chemistry project topic:

• Identify Your Interests: Consider your interests within the broad field of chemistry. Are you fascinated by organic synthesis, environmental chemistry, biochemistry, or another sub-discipline? Choosing a topic that aligns with your interests will keep you motivated throughout the project.
• Assess Your Knowledge and Skills: Evaluate your current knowledge and skills in chemistry. Choose a topic that challenges you without being too overwhelming. If you’re a beginner, opt for a project that allows you to build upon your existing knowledge while learning new concepts.
• Consider Available Resources: Take stock of the resources available to you, including laboratory equipment, chemicals, reference materials, and access to mentors or experts. Select a project that can be feasibly completed with the resources at your disposal.
• Review Literature and Current Trends: Conduct a literature review to explore recent advancements, emerging trends, and unresolved questions in your chosen area of interest. This will help you identify gaps in knowledge or areas where further research is needed, guiding your selection of a relevant project topic.
• Define Your Objectives and Goals: Clearly define your objectives and goals for the project. Determine what you aim to accomplish and what outcomes you hope to achieve. Your project topic should align with these objectives and contribute to fulfilling your academic or personal goals.
• Consult with Mentors or Advisors: Seek guidance from mentors, advisors, or faculty members who can provide insights and suggestions based on their expertise. Discuss potential project topics with them and solicit their feedback to ensure that your chosen topic is relevant and feasible.
• Brainstorm and Narrow Down Options: Brainstorm a list of potential project topics based on your interests, knowledge, resources, and goals. Narrow down your options by considering factors such as feasibility, novelty, and potential impact. Choose a topic that excites you and has the potential to make a meaningful contribution to the field of chemistry.
• Refine Your Topic and Formulate a Research Plan: Once you’ve selected a topic, refine it further by clearly defining your research question or hypothesis. Develop a research plan outlining the specific objectives, methods, and timeline for your project. Be prepared to adapt and refine your plan as you progress with your research.

By following these steps, you can select relevant chemistry project topics that align with your interests, goals, and resources, setting the stage for a successful and rewarding research experience.

201+ Chemistry Project Topics: Beginners To Advanced

Organic chemistry projects.

• Synthesis and characterization of aspirin.
• Extraction and analysis of caffeine from tea leaves.
• Isolation and identification of natural dyes from plants.
• Synthesis of biodiesel from vegetable oil.
• Investigating the acidity of fruit juices using titration.
• Synthesis of esters for fragrance applications.
• Preparation of soap from vegetable oils.
• Studying the effect of catalysts on organic reactions.
• Analysis of essential oils from aromatic plants.
• Synthesis and purification of acetaminophen.
• Investigating the properties of polymers.
• Extraction of DNA from fruits or vegetables.
• Synthesis of nylon-6,6.
• Investigating the effects of different solvents on crystallization.
• Studying the reactions of carbohydrates.
• Synthesis of biodegradable plastics.
• Analysis of food additives using chromatography.
• Investigating the process of fermentation.
• Synthesis and characterization of bioderived materials.
• Studying the properties of antioxidants in foods.

Inorganic Chemistry Projects

• Synthesis and characterization of metal oxides.
• Investigating the properties of transition metal complexes.
• Preparation of metal nanoparticles and their applications.
• Studying the formation and properties of zeolites.
• Synthesis of coordination compounds.
• Investigating the redox properties of metal ions.
• Preparation and characterization of metal alloys.
• Studying the properties of rare earth elements.
• Synthesis of metal-organic frameworks (MOFs).
• Investigating the catalytic properties of metal nanoparticles.
• Preparation and properties of superconductors.
• Synthesis of semiconductor materials.
• Investigating the properties of carbon allotropes (e.g., graphite, diamond).
• Preparation and characterization of magnetic materials.
• Studying the properties of chalcogenides.
• Synthesis of nanocomposites for catalytic applications.
• Investigating the properties of perovskite materials.
• Preparation and characterization of phosphors.
• Studying the properties of metal halides.
• Synthesis of metal carbonyl complexes.

Analytical Chemistry Projects

• Development of a method for heavy metal detection in water samples.
• Analysis of food preservatives using spectroscopic techniques.
• Determination of vitamin C content in fruit juices.
• Quantification of caffeine in beverages using chromatography.
• Development of a method for pesticide analysis in fruits and vegetables.
• Analysis of air pollutants using gas chromatography.
• Determination of pH in household products.
• Quantitative analysis of alcohol content in beverages.
• Development of a method for drug analysis in pharmaceutical formulations.
• Analysis of mineral content in water samples.
• Determination of total dissolved solids (TDS) in water samples.
• Quantification of sugar content in soft drinks.
• Development of a method for forensic analysis of trace evidence.
• Analysis of heavy metals in soil samples.
• Determination of acidity in vinegar samples.
• Quantitative analysis of proteins in biological samples.
• Development of a method for antioxidant analysis in food samples.
• Analysis of volatile organic compounds (VOCs) in indoor air.
• Determination of chlorophyll content in plant samples.
• Quantification of nicotine in tobacco products.

Physical Chemistry Projects

• Investigation of reaction kinetics using spectrophotometry.
• Study of gas laws through Boyle’s and Charles’s experiments.
• Determination of the heat of neutralization using calorimetry.
• Investigation of solubility equilibria using conductivity measurements.
• Study of colligative properties through freezing point depression.
• Determination of molecular weight using vapor pressure measurements.
• Investigation of electrochemical cells and their applications.
• Study of phase transitions using differential scanning calorimetry (DSC).
• Determination of rate constants using the method of initial rates.
• Investigation of adsorption phenomena using surface area measurements.
• Study of the behavior of ideal and non-ideal gases.
• Determination of activation energy using the Arrhenius equation.
• Investigation of chemical equilibria using Le Chatelier’s principle.
• Study of reaction mechanisms using isotopic labeling techniques.
• Determination of the heat capacity of solids using calorimetry.
• Investigation of diffusion and osmosis phenomena.
• Study of molecular spectroscopy using UV-Vis spectroscopy.
• Determination of reaction enthalpy using Hess’s law.
• Investigation of acid-base titrations and pH indicators.
• Study of reaction rates using temperature-dependent kinetics.

Biochemistry Projects

• Isolation and characterization of enzymes from biological sources.
• Study of enzyme kinetics using spectrophotometry.
• Investigation of metabolic pathways using biochemical assays.
• Study of protein structure and function using SDS-PAGE.
• Analysis of nucleic acids using gel electrophoresis.
• Investigation of cellular respiration using respirometry.
• Study of photosynthesis using chlorophyll fluorescence.
• Analysis of biomolecules using mass spectrometry.
• Investigation of DNA replication using PCR.
• Study of gene expression using reporter assays.
• Analysis of protein-protein interactions using co-immunoprecipitation.
• Investigation of membrane transport using permeability assays.
• Study of signal transduction pathways using ELISA.
• Analysis of enzyme inhibition using kinetic assays.
• Investigation of DNA damage using comet assays.
• Study of protein folding using circular dichroism spectroscopy.
• Analysis of cell viability using MTT assays.
• Investigation of apoptosis using flow cytometry.
• Study of protein purification using chromatography techniques.
• Analysis of lipid metabolism using TLC.

Environmental Chemistry Projects

• Analysis of heavy metal contamination in urban soils.
• Study of water quality parameters in local streams.
• Investigation of air pollution sources using atmospheric sampling.
• Study of the effects of acid rain on aquatic ecosystems.
• Analysis of microplastics in marine environments.
• Investigation of nutrient pollution in freshwater systems.
• Study of pesticide residues in agricultural soils.
• Analysis of landfill leachate contaminants.
• Investigation of emerging contaminants in drinking water.
• Study of oil spill remediation techniques.
• Analysis of pharmaceuticals in wastewater treatment plants.
• Investigation of the effects of climate change on soil microbiota.
• Study of ozone depletion in the stratosphere.
• Analysis of indoor air pollutants in residential homes.
• Investigation of eutrophication in freshwater lakes.
• Study of bioaccumulation and biomagnification in food chains.
• Analysis of heavy metal uptake in aquatic plants.
• Investigation of the effects of deforestation on soil erosion.
• Study of greenhouse gas emissions from agricultural activities.
• Analysis of pollutants in urban stormwater runoff.

Interdisciplinary Chemistry Projects

• Development of nanomaterials for drug delivery applications.
• Study of the chemistry of art conservation and restoration.
• Investigation of the role of chemistry in renewable energy technologies.
• Study of the chemistry of food preservation techniques.
• Analysis of chemical communication in ecological systems.
• Investigation of the chemistry of brewing and fermentation.
• Study of the chemistry of cosmetics and personal care products.
• Analysis of the chemistry of natural and synthetic dyes.
• Investigation of the chemistry of perfume formulation.
• Study of the chemistry of materials science and engineering.
• Analysis of the chemistry of medicinal plants and herbal remedies.
• Investigation of the chemistry of wine production and aging.
• Study of the chemistry of biodegradable plastics.
• Analysis of the chemistry of flavor compounds in foods.
• Investigation of the chemistry of natural products and pharmaceuticals.
• Study of the chemistry of soil fertility and nutrient cycling.
• Analysis of the chemistry of water treatment technologies.
• Investigation of the chemistry of alternative fuels.
• Study of the chemistry of insecticides and pest control.
• Analysis of the chemistry of nanotechnology applications.

Advanced Chemistry Projects

• Synthesis and characterization of novel organic frameworks.
• Investigation of reaction mechanisms using computational chemistry.
• Study of advanced spectroscopic techniques for molecular analysis.
• Analysis of chemical kinetics using ultrafast laser spectroscopy.
• Investigation of catalytic reactions using surface science techniques.
• Study of quantum chemistry principles and applications.
• Analysis of supramolecular assemblies and host-guest interactions.
• Investigation of molecular modeling and simulation methods.
• Study of advanced materials for energy storage and conversion.
• Analysis of chemical dynamics and reaction kinetics.
• Investigation of organometallic catalysis for organic synthesis.
• Study of advanced techniques in NMR spectroscopy.
• Analysis of photochemical reactions and photophysics.
• Investigation of electron transfer processes in biological systems .
• Study of theoretical approaches to chemical bonding.
• Analysis of advanced electrochemical techniques.
• Investigation of non-covalent interactions in molecular recognition.
• Study of advanced techniques in mass spectrometry.
• Analysis of quantum dots and their applications in nanotechnology.
• Investigation of chemical sensors and biosensors.

Chemistry Education Projects

• Development of interactive chemistry teaching modules.
• Investigation of inquiry-based learning approaches in chemistry education.
• Study of the use of multimedia resources in chemistry instruction.
• Analysis of student misconceptions in chemistry learning.
• Investigation of the effectiveness of laboratory experiments in teaching chemistry concepts.
• Study of collaborative learning strategies in chemistry education.
• Analysis of the integration of technology in chemistry classrooms.
• Investigation of the role of assessment in promoting conceptual understanding in chemistry.
• Study of the impact of hands-on activities on student engagement in chemistry.
• Analysis of the use of real-world applications to enhance chemistry learning.
• Investigation of the implementation of flipped classroom models in chemistry education.
• Study of the development of critical thinking skills in chemistry students.
• Analysis of the role of feedback in improving student performance in chemistry.
• Investigation of the use of peer teaching and tutoring in chemistry education.
• Study of the incorporation of environmental chemistry concepts in the curriculum.
• Analysis of the influence of classroom climate on student motivation in chemistry.
• Investigation of the role of metacognition in chemistry problem-solving.
• Study of the use of concept maps and graphic organizers in chemistry instruction.
• Analysis of the impact of teacher professional development on student achievement in chemistry.
• Investigation of the use of authentic assessments in chemistry education.

Chemistry Outreach Projects

• Development of chemistry demonstration shows for public outreach events.
• Investigation of community-based science education programs in chemistry.
• Study of chemistry-themed science fairs and competitions.
• Analysis of chemistry outreach activities in underserved communities.
• Investigation of the role of science communication in promoting chemistry awareness.
• Study of chemistry-themed podcasts and educational videos.
• Analysis of chemistry outreach efforts in museums and science centers.
• Investigation of chemistry-themed summer camps and workshops.
• Study of chemistry outreach initiatives in schools and universities.
• Analysis of chemistry outreach efforts on social media platforms.
• Investigation of the impact of chemistry outreach on public perception of science.
• Study of chemistry-themed citizen science projects.
• Analysis of chemistry outreach programs for adults and lifelong learners.
• Investigation of the use of storytelling in chemistry outreach.
• Study of chemistry-themed art and literature projects.
• Analysis of chemistry outreach collaborations with industry partners.
• Investigation of the role of role models and mentors in chemistry outreach.
• Study of chemistry-themed escape rooms and puzzle games.
• Analysis of chemistry outreach efforts during national science weeks.
• Investigation of the use of virtual reality and augmented reality in chemistry outreach.
• Study of chemistry-themed science cafés and public lectures.
• Analysis of the impact of chemistry outreach on career aspirations in STEM fields.

Chemistry projects offer a dynamic and engaging way to explore the diverse facets of chemical science. Whether synthesizing new compounds, analyzing environmental samples, or unraveling biochemical processes, these projects foster curiosity, critical thinking, and innovation.

By delving into various chemistry project topics, students and enthusiasts can deepen their understanding of the world’s chemical complexity while contributing to scientific knowledge and societal progress.

So, let’s embark on this exciting journey of discovery and uncover the wonders of chemistry together!

Related Posts

Step by Step Guide on The Best Way to Finance Car

The Best Way on How to Get Fund For Business to Grow it Efficiently

Leave a comment cancel reply.

Your email address will not be published. Required fields are marked *

• Research Paper Guides
• Research Paper Topics

200+ Chemistry Research Topics for Papers

• Speech Topics
• Basics of Essay Writing
• Essay Topics
• Other Essays
• Main Academic Essays
• Basics of Research Paper Writing
• Miscellaneous
• Chicago/ Turabian
• Data & Statistics
• Methodology
• Admission Writing Tips
• Admission Advice
• Other Guides
• Student Life
• Studying Tips
• Understanding Plagiarism
• Academic Writing Tips
• Basics of Dissertation & Thesis Writing

• Essay Guides
• Formatting Guides
• Basics of Research Process
• Admission Guides
• Dissertation & Thesis Guides

Table of contents

Use our free Readability checker

Do you find identifying suitable chemistry research topics difficult? You are not alone! Many students consider it challenging and time-consuming to choose an interesting chemistry topic for a research paper. In this blog post, we will discuss various research topics in chemistry to help simplify your research process. Continue reading to familiarize yourself with ideas from different fields and academic levels. Apart from defining research topics and discussing how to select one, we have provided examples to help kick-start your research project or assignments. Got a deadline approaching fast? Entrust your chemistry research paper to professional writers. Our academic service proceeds all ‘ write my paper for me ’ inquiries quickly and efficiently. Get your paper written now by an expert!

What Are Chemistry Research Topics?

Chemistry is a field of science that covers the structure, composition, and properties of elements and compounds. As a student taking this subject, you will encounter multiple experiments, chemical reactions, and analytical study methods. This branch of science can be subdivided into multiple areas, including organic, inorganic, biochemistry, physical, analytical, and nuclear science, among others. Chemistry research paper topics are talking points related to the branches of science outlined above. To ensure that all learning objectives are met, instructors may require students to work on various topics in chemistry. You would be expected to source your chemistry research topics ideas from all possible branches. In one instance, your topic could be associated with analytical science, in another - with practical discussions, which is an entirely different thing despite both areas being categorized as chemistry subfields.

Characteristics of Good Chemistry Research Topics

Selecting a good research topic for chemistry plays a vital role in determining the probability of success when writing your paper. It is, therefore, important to know the characteristics of good chemistry topics for a research paper. Although you can derive discussions from many sub-areas, these research topic ideas share many common characteristics. A great research topic should be:

• Precise, meaningful, clear, and straightforward
• Analytical and researchable using logical methodologies
• Of theoretical or practical significance
• Supported by numerous academic evidence and sources.

How to Choose a Chemistry Research Topic?

Chemistry is a broad subject with multiple research areas. If you are not keen enough, you may easily get lost in its variety and fail to select a congenial title. So, how do you deal with this issue? In a nutshell, the process comes down to two aspects – your passion and competence. Below are step-by-step guidelines that you can follow to determine interesting topics about chemistry:

• Pick chemistry research topics with your knowledge capabilities in mind. Do not choose a topic that is beyond your academic level.
• Choose something that is interesting to you. If you are fascinated with the selected topic, you will find responding to the research questions to be much simpler.
• Select a research title that is convenient to work on due to the sufficient amount and availability of existing evidence and references.
• Ensure that the chosen chemistry topics for research paper are within the subfield you are majoring in and that it meets your instructor’s requirements.

Once you select the most appropriate title, see how to write a research paper like an expert.

Chemistry Research Paper Topics List

There are many research topics for chemistry to choose from. In this section, we have compiled examples of the best topics from various sub-areas. Below is a list of chemistry research topics for papers:

• Latest developments in DNA technology.
• Negative effects of using pesticides in food production.
• Importance and potential drawbacks of using fertilizer in commercial agriculture.
• Acids and bases: composition, properties, and applications.
• Industrial chemicals and environmental pollution.
• Dangers and side effects of using ibuprofen.
• Acid-base neutralization process.
• Air pollution implication on global warming and climate change.
• Ageing and the brain.
• Catalytic reaction mechanisms.

The chemistry research topics list above is created by drawing ideas from different sub-areas, thus covering a significant part of scholars’ inquiries.

Interesting Topics in Chemistry

In some instances, one may select a research topic because it is just fascinating. There are interesting chemistry topics that can explain intriguing phenomena in your day-to-day life. Alternatively, you can also opt for something related to essential issues in the current society. Here are sample chemistry interesting topics you can research into:

• Composition and effects of e-cigarettes.
• Food dye composition.
• Measuring electrical conductivity in a salt solution.
• How to change a penny’s color to gold.
• The scientific explanation of foam formation.
• Silicon usage in cosmetic surgery.
• Evidence and application of surface tension in day-to-day life.
• Examining pesticide residue in farm products from different grocery stores.
• How does molecule composition affect the physical appearance of things?
• Sodium metal reaction on water surfaces.
• How to separate dissolved sugar from water.
• How to clean up oil spills at sea.
• Rust formation on metal surfaces.
• How to chemically remove rust from stainless steel.
• The science behind turning boiling water into “snow” in a cold winter.

Easy Chemistry Research Topics

The science studied in high schools is way simpler compared to postgraduate one. You can find easy chemistry topics to research if you focus on certain academic levels and sub-areas. For example, physical chemistry has easy chemistry topics to do research paper on. On the other side, inorganic or analytical sub-areas tend to offer scientific research research topics that are more technical. The list below outlines easy topic examples you can pick from:

• Determining the percentage composition of oxygen in the air.
• Patterns in the periodic table.
• Atomic theory: primary principles and applications.
• Chemical and physical properties of starch.
• Determining the pH level of various liquids.
• Properties of acids and bases.
• Why is glass the preferred material in laboratories?
• Balancing chemical equations.
• Analyzing different chemical bonds.
• Alkali metals and their properties.
• General characteristics of metals.
• Noble gasses: properties and reaction characteristics.
• Water purification methods.
• The periodic table: its historical background.
• Alkaline earth metals: properties and reactivity.

Innovative Research Topics in Chemistry

Innovative chemistry topics for research paper relate to new ideas and ways to go about things. Using these ground-breaking topics related to chemistry, you can discuss new materials or methodologies. If you are interested in innovative research topics, here are some examples you can borrow from:

• Gene modification in medical chemistry .
• Improved cancer treatment using bacteria-based biohybrid microrobots.
• New methods used to detect explosive residues.
• Studying the molecular makeup of particles in space.
• Substitute for pesticides in farming.
• Nanophotonics in aeronautics.
• Nanomaterials production process and techniques.
• Clean energy alternatives for fossil fuels.
• Photocatalysis usage in 3D printing technology.
• Biodegradable polymers as alternatives for plastics.
• Silicon dioxide usage in solar cells.
• Chemical reactions in lithium-ion batteries.
• Self-healing concrete: basic principles.
• New materials for lightweight planes and vehicles.
• Polymer analysis in a restricted environment.

Cool Chemistry Research Topics

Sometimes, our title selection might be guided by how cool and fun the study results will be. If you are looking for cool chemistry topics to research on, you are in the right place. We have compiled some cool chemistry topics for you to choose from.

• How World War II influenced computational chemistry.
• How do chemicals in our brains create different moods?
• Composition and properties of laughing gas.
• European alchemy: historical background and its impact on modern science.
• Developing a film at home: chemicals required and process.
• Why lemon juice stops apples from browning.
• Different flame colors and their scientific explanation.
• Using a potato to light a bulb.
• Principles of chromatography.
• Utilizing cloud seeding in alleviating drought conditions.
• Finding iron in a mixture of metals.
• Gas chromatography: how it works and its applications.
• Application of vibrational spectroscopy.
• Surface tension and the dish soap experiment.
• How to make a homemade water filter.

Have you spotted any ideas but can’t get the research process started? Contact our professional writing service where you can pay for research paper and be sure that you will get outstanding results within your deadline. 

Intriguing Chemistry Topics for Research

There are many chemistry topics to write about. However, not all topics are intriguing (and frankly, most are the other way around). Below are topic examples that can instantly draw readers’ attention:

• Non-existing chemical compounds.
• Molecular structure of artificial honey as compared to natural honey.
• Stem cell studies: ethical implications.
• Principles of polymerase chain reaction and DNA replication.
• Organic chemistry applications in our daily living.
• Chemicals as weapons of mass destruction.
• How does adding sugar to a soft drink affect its density?
• Synthetic molecules in the pharmaceutical industry .
• Aerosol formation and its application in body spray manufacture.
• Analyzing the gasoline production process.
• Benzene molecular structure and its use in the cosmetic industry.
• Why are 96,000,000 black balls dumped into the LA reservoir?
• Water recycling methods.
• The discovery of oxygen.
• Importance of esters in our day-to-day living.

If you closely review the research topics for chemistry paper above, you will find them arousing your curiosity much more than the ones in other sections. These topics will challenge your initial line of thinking or introduce you to the concepts that just stand out.

Unique Chemistry Research Topics

There are some chemistry paper topics that are rarely worked on by students. People ignore these topics because they are either complex or lack adequate conclusive information from previous studies. If you are brave enough and wish to have a unique presentation, you can consider the research topics in chemistry below:

• Organosilicon compounds and their use.
• Nucleophiles and electrophiles.
• Molecular structure of Teflon and its industrial application.
• Sodium azide usage in automobile airbags.
• Dangers of COVID-19 tests that use sodium azide as the reaction reagent.
• Chemical composition of steroids and their effects on human beings.
• Artificial diamond production process.
• Insulin production biotechnology.
• Evolution of lethal injection.
• Effects of chiral class drugs on human health.
• Chemical residues in livestock.
• Artificial organs and their potential implication on transplantation.
• Role of nanoreactors in nanotechnology and biotechnology.
• Dangers of phosgene to human health.
• Production of dry ice.

Popular Chemistry Research Paper Topics

Unlike the unique study subjects discussed in the previous section, popular topics relating to chemistry are widely researched. Students favor these topics due to reasons like their simplicity, availability of adequate evidence, and their relevance to current issues. You can pick a hot topic in chemistry from the list below:

• Metal oxide usage in electronics.
• Importance of nitrogen to human survival.
• How do temperature changes affect chemical reactions?
• Lewis structure for ionic compounds.
• Analysis of the hydrophobic effect.
• Hydrogen as an alternative to fossil fuel.
• Application of thermodynamics law in our lives.
• pH level calculations and analysis.
• Gas laws and their application.
• Why is Earth viewed as a closed thermodynamic system?
• Redox reactions and their industrial applications.
• Decomposition process of polymers.
• The anomalous expansion of water.
• Impact of fluoride ion on dental health .
• The use of lithium, magnesium, and calcium compounds in clinical medicine.

>> View more: Medical Research Paper Topics

Controversial Chemistry Topics for Papers

Just like in any other subject, there exist chemistry project topics that are controversial in nature. People are understandably more passionate about some subject matters compared to others. Discussions related to, for instance, chemical usage in battlefields and the health effects of using certain chemicals tend to attract heated debates. Below are some controversial topics in chemistry that you can write about:

• Biochemicals usage in warfare.
• Impact of fast-food chemicals on the human brain.
• Gene modification in human embryos.
• Bioconjugation techniques and how they are used in drug delivery.
• Synthetic molecules replication techniques.
• Use of lethal injection in execution of criminals.
• Ethical justification for euthanasia.
• Manufacture of chemical poisons.
• Fritz Haber’s controversial inventions.
• Artificial organs and their role in healthcare.
• Electromagnetic energy conversion to chemical energy.
• Dangers of using fertilizer in farming.
• Analyzing the water memory effect.
• Synthesis of food from non-edible items.
• Bio-inspired molecular machines and their applications.

Chemistry Research Ideas for Students

Students are often required to work on some chemistry project ideas to successfully complete their course. Depending on the sub-area one specializes in, and the academic level, research matters will vary significantly. For instance, chemistry undergraduate research project ideas are incomparable to highschool research titles. Some subject matters are only suitable for professional research. This section sorts the research ideas into their respective academic levels.

Chemistry Research Topics for High School

Chemistry research project ideas for highschool students are relatively easy compared to higher academic levels. The tasks are not very demanding in terms of the research methodologies used and the time required to complete them. At this level, students are introduced to the basic concepts of the subject. Common chemistry topics for high school are outlined in the list below.

• Acids and bases in the reduction-oxidation reaction.
• Importance of studying chemicals and chemical processes in high school.
• Ionization techniques for the mass spectrometry process.
• Avogadro’s Law: analysis, formulae, and application.
• Thermochemistry lab experiments.
• Laboratory safety rules.
• The hydrolysis analysis.
• Acids: structural composition, properties, and use.
• Noble gasses configuration.
• States of matter and their characteristics.
• Optimizing indoor plants life through chemistry.
• Role of enzymes in chemical and biological reactions.
• Thermal effects of chemical reactions.
• The law of multiple proportions in chemical reactions.
• Constant and changing variables in Boyle’s law .

Chemistry Research Topics for College Students

Chemistry project ideas for college often require students to dive deep into a subject. Rather than explaining the basic concepts, you may be instructed to apply them in addressing problems. A college chemistry project will require you to dedicate more time and conduct more research. Below are some of the title ideas for college students and undergraduates:

• How much energy is produced from burning nuts and chips?
• Dangers of using radon in construction and potential solutions.
• Chemical composition of aspirin and its effect on human physiology.
• Green chemistry application in the food industry.
• Phosphorescence versus fluorescence.
• Dihydroxyacetone phosphate conversion.
• Big data and biocomputing in chemical studies.
• Thermoelectric properties of materials.
• Artificial organic tissue development in laboratories.
• Nuclear fusion: primary concepts and applications.
• Power production process in lithium nickel batteries.
• Medico-biological importance of group 3B and 4B elements.
• Global cycle of biologically active elements.
• Importance of chemical knowledge in cancer treatment.
• Inorganic materials usage in the military.

Chemistry Research Topics in Different Fields

Chemistry can be divided into many sub-areas. Each subfield has interesting chemistry topics to research into. To choose a research topic in chemistry, you need to first determine a sub-area you would wish to specialize in. However, even within these fields, there are still many title options to choose from. To help reduce the confusion and simplify the selection process, we have categorized potential research discussions into their respective sub-areas.

Organic Chemistry Research Topics

Organic chemistry mainly involves studying the structure, composition, properties, and reaction of carbon-based compounds. It is among the most commercially applied subfields, which makes organic chemistry research paper topics very common. I am sure you must have encountered products manufactured using organic chemistry principles within your surroundings. If you wish to learn more about these products, you can explore these latest research topics in organic chemistry:

• Pain relief medicine: chemical structure and composition.
• Composition, use, and effects of polymers.
• Retin-A usage in acne treatment.
• Organic chemistry usage and application in daily life.
• Types of organic compounds isomerism.
• Aromatic hydrocarbons as industrial raw materials.
• Alcohol hydrophilicity in aqueous solutions.
• Physical and chemical properties of polyhydric alcohols.
• Synthetic polymer applications: synthetic fiber, Teflon, and isoprene rubber.
• Fetal alcohol syndrome: types and symptoms.
• Structure and properties of phenols.
• The application of organic chemistry in birth control.
• Nucleic acid stability.
• Parameters affecting proton chemical shifts.
• Structure and properties of lipids.

Inorganic Chemistry Research Topics

This branch deals with the study of structure, composition, and properties of materials that do not contain carbon. Research paper topics for inorganic chemistry focus on metals, minerals, and inorganic compounds. The list below compiles chemistry projects topics and ideas related to inorganic chemistry.

• How to create new and improve existing alloys.
• Implication of inorganic chemistry on the environment.
• Application of inorganic chemistry in the cosmetic industry.
• Interaction between sulfuric acid and organic materials.
• Lattice energy and enthalpy for different ionic bonds.
• Characteristics of different types of nucleosyntheses.
• Uniqueness of hydrogen bonds and polarity.
• Hard and soft acids and bases ( HSAB ) theory.
• Dalton’s Law: principles and applications.
• Structure of a gemstone and how it impacts its appearance.
• Relationship between inorganic and biochemistry.
• Parameters affecting Bronsted-Lowry acidity.
• Crystal field theory: analysis and disadvantages.
• Application of angular overlap model.
• Primary laws of photochemistry.

Analytical Chemistry Research Topics

The determination of the objects’ primary makeup of objects is the main interest of this branch. Various analytical methods, including spectroscopy, chromatography, and electroanalytical techniques, are often discussed in the subfield. As such, many analytical chemistry research paper topics focus on these or other analysis techniques. Below is a list of research topics on analytical chemistry:

• Analytical techniques used in forensic science.
• Examining the electroanalytical techniques.
• Importance of analytical chemistry to the environment.
• Miniaturization and its use in analyzing pharmaceutical substances.
• Evaluating the working principles of activation analysis.
• Gravimetric analysis principles.
• GMOs usage and their potential hazards to human health.
• Potentiometric measurement methods.
• Liquid and gas chromatography.
• Spectroscopy methods and their use in detecting and quantifying molecular and structural composition of samples.
• Dispersive X-ray analysis of tissues.
• Analytical methods for determining the side effects of ibuprofen usage.
• Benefits of the isomerism framework.
• Acid-base titration as a quantitative analysis technique.
• Application of spectroscopy in medicine.

Environment Chemistry Topics for Research

The apparent global warming and climate change threats have led to the development of a new area of study. This sub-area has project topics in chemistry that explore the impact of human activity on the environment and the potential solutions for slowing down and reversing the climate change process. Common environmental chemistry related topics include:

• Negative effects of deep-sea mining.
• Ground water contamination: causes, dangers, and potential solutions.
• Oil spillage and its effect on marine life.
• Effect of heat engines on the environment.
• Safe disposal of toxic waste.
• Global warming: causes and potential remedies.
• Potential alternatives to fossil fuels.
• Innovative methods to minimize pesticide usage in agriculture.
• Cultivated meat as an alternative to livestock farming.
• How efficient is artificial photosynthesis.
• The Chernobyl ecological disaster.
• Analysis of life-cycle assessment (LCA).
• Environmental benefits of using energy-saving lamps.
• Environmental pollution by nano toxins.
• Potential solutions for global warming.

Need more ideas on the environment? Check our list of the best environmental research topics for students. 

Physical Chemistry Research Topics

Physical chemistry is the study of the behavior of matter. Physical chemistry topics for research papers focus on analyzing the physical and chemical properties of atoms and molecules and how they interact with each other. You can use a project topic on chemistry from the list below:

• Surface tension and its impact on mixtures.
• Diffusion of liquid and gasses.
• Reaction of bromine under UV rays.
• Pressure effect in chemical reactions.
• Bonding between atoms and molecules.
• Analyzing Schrodinger’s equation.
• Hess’s laws: principles and application.
• Effects of intermolecular forces on the melting point of a material.
• Entropy law of thermodynamics.
• Relationship between quantum mechanics and atomic orbitals.
• Chemical kinetics in pharmacy.
• Analyzing the physical and chemical indicators of milk.
• How to determine atoms’ electron configuration.
• Why isotopes exist.
• Determining the group based on its successive ionization energies.

Chemical Engineering Research Topics

In this section, we will discuss research topics of chemistry related to the design and application of chemical processes. Here are some of the chemical research project ideas that will impress your instructor:

• Chemical engineering concepts in the food production industry.
• Analyzing wastewater treatment techniques.
• Conversion of rocket fuel to energy.
• Analyzing different mixture separation techniques.
• Industrial application of chemical engineering concepts.
• Non-reactive mass balances and mass balance with reaction.
• Binary distillation and its application.
• Gas absorption usage in the chemical industry.
• Reaction kinetics in a plug flow reactor.
• Water splitting for hydrogen production.
• The application of MIMO theory in the control of chemical process operation.
• Chemical engineering applications in the healthcare sector.
• Nanofiltration member usages in pharmaceutical wastewater treatment.
• General overview of microfluidics.
• Production of high-quality foam.

Nuclear Chemistry Research Topics

A nuclear chemistry research project deals with radioactivity-related processes. You may encounter this branch of science in nuclear energy production, military applications, and even in the hospital. Some of the researchable topics in chemistry of nuclei transformation include:

• Computation of an element’s half-life.
• Radioactive elements in real life and how they are being used.
• Nuclear fusion: the process and its function.
• Types of radioactive decay.
• Effects of radiation on biological systems.
• Safe radioactive waste disposal.
• Application of nuclear science in the healthcare sector.
• Analyzing the three types of radiation.
• How to destroy toxic organic compounds using irradiation.
• Is there a possibility of cold fusion ever happening?
• Biological application of radiochemistry.
• Dangerous consequences of ionizing versus non-ionizing radiation.
• Optical chemo sensors: principles and applications.
• Interaction between water and radioactive materials.
• Radiation accident cases in human history.

There is a vast assortment of research ideas for your study on our platform. Be it biology research topics or nursing research paper topics , we have all of them here.

Bottom Line on Chemistry Research Topics

In sum, chemistry is a broad subject with multiple sub-areas. Depending on your preference, you can choose interesting chemistry research topics for papers from the many subfields. Apart from selecting a good research subject, also remember that is always mandatory to adhere to proper writing procedures! Besides, select chemistry essay topics that will keep you excited till the end of research, as you wouldn’t want to quit in the middle and switch to another topic. If you combine all provided tips together, you will definitely find it easy to select and work on research in chemistry topics.

Our academic writing service is always happy to help. Our platform was created by students who also struggled. So the writers deliver excellent papers focusing on fast and high-quality writing. 

Joe Eckel is an expert on Dissertations writing. He makes sure that each student gets precious insights on composing A-grade academic writing.

Research Topics & Ideas: Environment

100+ Environmental Science Research Topics & Ideas

Finding and choosing a strong research topic is the critical first step when it comes to crafting a high-quality dissertation, thesis or research project. Here, we’ll explore a variety research ideas and topic thought-starters related to various environmental science disciplines, including ecology, oceanography, hydrology, geology, soil science, environmental chemistry, environmental economics, and environmental ethics.

NB – This is just the start…

The topic ideation and evaluation process has multiple steps . In this post, we’ll kickstart the process by sharing some research topic ideas within the environmental sciences. This is the starting point though. To develop a well-defined research topic, you’ll need to identify a clear and convincing research gap , along with a well-justified plan of action to fill that gap.

If you’re new to the oftentimes perplexing world of research, or if this is your first time undertaking a formal academic research project, be sure to check out our free dissertation mini-course. Also be sure to also sign up for our free webinar that explores how to develop a high-quality research topic from scratch.

Overview: Environmental Topics

• Ecology /ecological science
• Atmospheric science
• Oceanography
• Soil science
• Environmental chemistry
• Environmental economics
• Environmental ethics
• Examples  of dissertations and theses

Topics & Ideas: Ecological Science

• The impact of land-use change on species diversity and ecosystem functioning in agricultural landscapes
• The role of disturbances such as fire and drought in shaping arid ecosystems
• The impact of climate change on the distribution of migratory marine species
• Investigating the role of mutualistic plant-insect relationships in maintaining ecosystem stability
• The effects of invasive plant species on ecosystem structure and function
• The impact of habitat fragmentation caused by road construction on species diversity and population dynamics in the tropics
• The role of ecosystem services in urban areas and their economic value to a developing nation
• The effectiveness of different grassland restoration techniques in degraded ecosystems
• The impact of land-use change through agriculture and urbanisation on soil microbial communities in a temperate environment
• The role of microbial diversity in ecosystem health and nutrient cycling in an African savannah

Topics & Ideas: Atmospheric Science

• The impact of climate change on atmospheric circulation patterns above tropical rainforests
• The role of atmospheric aerosols in cloud formation and precipitation above cities with high pollution levels
• The impact of agricultural land-use change on global atmospheric composition
• Investigating the role of atmospheric convection in severe weather events in the tropics
• The impact of urbanisation on regional and global atmospheric ozone levels
• The impact of sea surface temperature on atmospheric circulation and tropical cyclones
• The impact of solar flares on the Earth’s atmospheric composition
• The impact of climate change on atmospheric turbulence and air transportation safety
• The impact of stratospheric ozone depletion on atmospheric circulation and climate change
• The role of atmospheric rivers in global water supply and sea-ice formation

Topics & Ideas: Oceanography

• The impact of ocean acidification on kelp forests and biogeochemical cycles
• The role of ocean currents in distributing heat and regulating desert rain
• The impact of carbon monoxide pollution on ocean chemistry and biogeochemical cycles
• Investigating the role of ocean mixing in regulating coastal climates
• The impact of sea level rise on the resource availability of low-income coastal communities
• The impact of ocean warming on the distribution and migration patterns of marine mammals
• The impact of ocean deoxygenation on biogeochemical cycles in the arctic
• The role of ocean-atmosphere interactions in regulating rainfall in arid regions
• The impact of ocean eddies on global ocean circulation and plankton distribution
• The role of ocean-ice interactions in regulating the Earth’s climate and sea level

Tops & Ideas: Hydrology

• The impact of agricultural land-use change on water resources and hydrologic cycles in temperate regions
• The impact of agricultural groundwater availability on irrigation practices in the global south
• The impact of rising sea-surface temperatures on global precipitation patterns and water availability
• Investigating the role of wetlands in regulating water resources for riparian forests
• The impact of tropical ranches on river and stream ecosystems and water quality
• The impact of urbanisation on regional and local hydrologic cycles and water resources for agriculture
• The role of snow cover and mountain hydrology in regulating regional agricultural water resources
• The impact of drought on food security in arid and semi-arid regions
• The role of groundwater recharge in sustaining water resources in arid and semi-arid environments
• The impact of sea level rise on coastal hydrology and the quality of water resources

Topics & Ideas: Geology

• The impact of tectonic activity on the East African rift valley
• The role of mineral deposits in shaping ancient human societies
• The impact of sea-level rise on coastal geomorphology and shoreline evolution
• Investigating the role of erosion in shaping the landscape and impacting desertification
• The impact of mining on soil stability and landslide potential
• The impact of volcanic activity on incoming solar radiation and climate
• The role of geothermal energy in decarbonising the energy mix of megacities
• The impact of Earth’s magnetic field on geological processes and solar wind
• The impact of plate tectonics on the evolution of mammals
• The role of the distribution of mineral resources in shaping human societies and economies, with emphasis on sustainability

Topics & Ideas: Soil Science

• The impact of dam building on soil quality and fertility
• The role of soil organic matter in regulating nutrient cycles in agricultural land
• The impact of climate change on soil erosion and soil organic carbon storage in peatlands
• Investigating the role of above-below-ground interactions in nutrient cycling and soil health
• The impact of deforestation on soil degradation and soil fertility
• The role of soil texture and structure in regulating water and nutrient availability in boreal forests
• The impact of sustainable land management practices on soil health and soil organic matter
• The impact of wetland modification on soil structure and function
• The role of soil-atmosphere exchange and carbon sequestration in regulating regional and global climate
• The impact of salinization on soil health and crop productivity in coastal communities

Topics & Ideas: Environmental Chemistry

• The impact of cobalt mining on water quality and the fate of contaminants in the environment
• The role of atmospheric chemistry in shaping air quality and climate change
• The impact of soil chemistry on nutrient availability and plant growth in wheat monoculture
• Investigating the fate and transport of heavy metal contaminants in the environment
• The impact of climate change on biochemical cycling in tropical rainforests
• The impact of various types of land-use change on biochemical cycling
• The role of soil microbes in mediating contaminant degradation in the environment
• The impact of chemical and oil spills on freshwater and soil chemistry
• The role of atmospheric nitrogen deposition in shaping water and soil chemistry
• The impact of over-irrigation on the cycling and fate of persistent organic pollutants in the environment

Topics & Ideas: Environmental Economics

• The impact of climate change on the economies of developing nations
• The role of market-based mechanisms in promoting sustainable use of forest resources
• The impact of environmental regulations on economic growth and competitiveness
• Investigating the economic benefits and costs of ecosystem services for African countries
• The impact of renewable energy policies on regional and global energy markets
• The role of water markets in promoting sustainable water use in southern Africa
• The impact of land-use change in rural areas on regional and global economies
• The impact of environmental disasters on local and national economies
• The role of green technologies and innovation in shaping the zero-carbon transition and the knock-on effects for local economies
• The impact of environmental and natural resource policies on income distribution and poverty of rural communities

Topics & Ideas: Environmental Ethics

• The ethical foundations of environmentalism and the environmental movement regarding renewable energy
• The role of values and ethics in shaping environmental policy and decision-making in the mining industry
• The impact of cultural and religious beliefs on environmental attitudes and behaviours in first world countries
• Investigating the ethics of biodiversity conservation and the protection of endangered species in palm oil plantations
• The ethical implications of sea-level rise for future generations and vulnerable coastal populations
• The role of ethical considerations in shaping sustainable use of natural forest resources
• The impact of environmental justice on marginalized communities and environmental policies in Asia
• The ethical implications of environmental risks and decision-making under uncertainty
• The role of ethics in shaping the transition to a low-carbon, sustainable future for the construction industry
• The impact of environmental values on consumer behaviour and the marketplace: a case study of the ‘bring your own shopping bag’ policy

Examples: Real Dissertation & Thesis Topics

While the ideas we’ve presented above are a decent starting point for finding a research topic, they are fairly generic and non-specific. So, it helps to look at actual dissertations and theses to see how this all comes together.

Below, we’ve included a selection of research projects from various environmental science-related degree programs to help refine your thinking. These are actual dissertations and theses, written as part of Master’s and PhD-level programs, so they can provide some useful insight as to what a research topic looks like in practice.

• The physiology of microorganisms in enhanced biological phosphorous removal (Saunders, 2014)
• The influence of the coastal front on heavy rainfall events along the east coast (Henson, 2019)
• Forage production and diversification for climate-smart tropical and temperate silvopastures (Dibala, 2019)
• Advancing spectral induced polarization for near surface geophysical characterization (Wang, 2021)
• Assessment of Chromophoric Dissolved Organic Matter and Thamnocephalus platyurus as Tools to Monitor Cyanobacterial Bloom Development and Toxicity (Hipsher, 2019)
• Evaluating the Removal of Microcystin Variants with Powdered Activated Carbon (Juang, 2020)
• The effect of hydrological restoration on nutrient concentrations, macroinvertebrate communities, and amphibian populations in Lake Erie coastal wetlands (Berg, 2019)
• Utilizing hydrologic soil grouping to estimate corn nitrogen rate recommendations (Bean, 2019)
• Fungal Function in House Dust and Dust from the International Space Station (Bope, 2021)
• Assessing Vulnerability and the Potential for Ecosystem-based Adaptation (EbA) in Sudan’s Blue Nile Basin (Mohamed, 2022)
• A Microbial Water Quality Analysis of the Recreational Zones in the Los Angeles River of Elysian Valley, CA (Nguyen, 2019)
• Dry Season Water Quality Study on Three Recreational Sites in the San Gabriel Mountains (Vallejo, 2019)
• Wastewater Treatment Plan for Unix Packaging Adjustment of the Potential Hydrogen (PH) Evaluation of Enzymatic Activity After the Addition of Cycle Disgestase Enzyme (Miessi, 2020)
• Laying the Genetic Foundation for the Conservation of Longhorn Fairy Shrimp (Kyle, 2021).

Looking at these titles, you can probably pick up that the research topics here are quite specific and narrowly-focused , compared to the generic ones presented earlier. To create a top-notch research topic, you will need to be precise and target a specific context with specific variables of interest . In other words, you’ll need to identify a clear, well-justified research gap.

Need more help?

If you’re still feeling a bit unsure about how to find a research topic for your environmental science dissertation or research project, be sure to check out our private coaching services below, as well as our Research Topic Kickstarter .

Need a helping hand?

You Might Also Like:

research topics on climate change and environment

I wish to learn things in a more advanced but simple way and with the hopes that I am in the right place.

Thank so much for the research topics. It really helped

the guides were really helpful

Research topics on environmental geology

Thanks for the research topics….I need a research topic on Geography

I want the research on environmental planning and management

I want a topic on environmental sustainability

It good coaching

Submit a Comment Cancel reply

Your email address will not be published. Required fields are marked *

Save my name, email, and website in this browser for the next time I comment.

• Print Friendly

Your browser is not supported

Sorry but it looks as if your browser is out of date. To get the best experience using our site we recommend that you upgrade or switch browsers.

Find a solution

• Skip to main content
• Skip to navigation
• hot-topics Extras
• Newsletters
• Reading room

Tell us what you think. Take part in our reader survey

Celebrating twenty years

• Back to parent navigation item
• Collections
• Water and the environment
• Chemical bonding
• Antimicrobial resistance
• Energy storage and batteries
• AI and automation
• Sustainability
• Research culture
• Nobel prize
• Food science and cookery
• Plastics and polymers
• Periodic table
• Coronavirus

• More from navigation items

Structural disorder key to high-capacitance carbon electrodes

• No comments

Structural disorder increases the capacitance of carbon supercapacitor electrodes, according to new findings from a team of UK-based researchers. The discovery could lead to the development of supercapacitors that can store more charge.

Supercapacitors generally comprise porous electrodes soaked in an electrolyte. The most common and cheapest electrodes are made of activated carbon, which is itself composed of graphene-like sheets that form a porous network containing a range of pore sizes. When the electrode is charged, ions of opposite charge from the electrolyte are reversibly adsorbed into the pores and ions of like charge are expelled.

However, the factors governing the capacitance of a carbon supercapacitor electrode have remained unclear. Some research has suggested it increases as pore size shrinks, but more recent research has contradicted this. ‘These porous carbon electrodes are really hard to characterise because they have inherently non-crystalline structures,’ says materials chemist Alexander Forse from the University of Cambridge.

In 2013, as part of his PhD in Clare Grey ’s group at Cambridge, Forse performed solid-state NMR on electrodes soaked with electrolytes. When the electrodes were prepared at lower temperatures, the adsorbed species showed lower chemical shifts. This showed that their nanoporous structures were chemically more disordered. ‘In this more recent study, Clare and I teamed up again to see “Is there a connection between this more disordered structure and the amount of energy you can store?”’ says Forse, now an assistant professor himself.

Pore size vs disorder

Researchers in Forse’s group led by his PhD student Xinyu Liu tested ten commercial nanoporous carbon electrodes from different suppliers in the standard commercial electrolyte tetraethylammonium tetrafluoroborate in acetonitrile. Five had very similar distributions of pore sizes, but their capacitance varied dramatically. When the researchers looked at the solid-state NMR spectra, they found that, when the chemical shift of the adsorbed species went down, the capacitance of the electrode went up. This was true irrespective of the adsorbed species, suggesting it was a property of the electrodes.

Source: © Nathan Pitt/University of Cambridge

Grey, Liu and Forse used solid-state NMR spectroscopy to analyse a range of commercial nanoporous carbon electrodes and uncover the link between structural disorder and capacitance

The researchers then annealed their most disordered carbon sample at a range of temperatures. They found that, the higher the annealing temperature, the higher the final chemical shifts and the lower the capacitance. The researchers are now working to understand the physical origin of the phenomenon. ‘We have evidence for the correlation but we can’t really say why a more disordered electrode is actually better,’ says Forse. They suspect it may be because increased localisation of charge at defects increases a surface’s local interaction with ions. The researchers then hope to use their discovery to design even higher-capacity electrodes.

Materials chemist Yury Gogotsi from Drexel University in Pennsylvania, US, says that researchers in his lab recognised an influence of disorder ‘over a dozen years ago’ when they were disappointed to find that high-temperature experiments that increased the specific surface area of carbide-derived carbon electrodes reduced their capacitance. However, he notes that until now there has been no real way to correlate disorder to capacitance and that the link with chemical shift shown in the NMR experiments is ‘a really important finding and the key to evaluating materials quantitatively’.

X Liu  et al ,  Science , 2024, DOI:  10.1126/science.adn6242

More from Tim Wogan

Algorithm designs proteins from scratch that can bind drugs and small molecules

Iodide addition could make high energy lithium-sulfur batteries commercially viable

Deep learning algorithm predicts structures of biomolecular assemblies

• Analytical chemistry
• Electronic materials
• Nanomaterials
• Nanoscience
• Physical chemistry
• Spectroscopy

Related articles

Supercapacitor cement could supercharge renewable energy storage

2023-08-07T08:45:00Z

By Tim Wogan

Building better batteries

2023-04-24T10:57:00Z

By James Mitchell Crow

Switching protocol doubles carbon capture capacity of supercapacitors

2022-06-22T12:55:00Z

By Edward Gardner

Mystery of discrepancies in speed of sound in water cleared up by study of ions

2024-04-23T13:33:00Z

By Anna Demming

Conserving Barbie from degradation

2024-04-22T08:48:00Z

By Rachel Brazil

Single atom layer of gold produced for the first time

2024-04-19T08:30:00Z

By Julia Robinson

No comments yet

Only registered users can comment on this article., more from news.

New mechanism identified that is potentially linked to very early stages of Alzheimer’s

2024-04-25T13:30:00Z

By Tosin Thompson

E. coli engineered to become methanol addict to make industry feedstocks

2024-04-24T09:16:00Z

By Bradley van Paridon

Light-driven enzyme engineered and repurposed to catalyse unnatural reaction

2024-04-23T08:30:00Z

By James Urquhart

US National Academy of Sciences launches $8m fund to support Ukraine’s science community

2024-04-22T13:30:00Z

By Rebecca Trager

Explainer: nitazenes and xylazine – a cause for concern

Canada pledges dramatic pay rise for PhDs, postdocs – but many will not benefit

2024-04-19T14:58:00Z

• Contributors
• Terms of use
• Accessibility
• Permissions
• This website collects cookies to deliver a better user experience. See how this site uses cookies .
• This website collects cookies to deliver a better user experience. Do not sell my personal data .
• Este site coleta cookies para oferecer uma melhor experiência ao usuário. Veja como este site usa cookies .

Site powered by Webvision Cloud

share this!

April 25, 2024

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:

fact-checked

peer-reviewed publication

trusted source

Chemical rope trick at molecular level: Mechanism research helps when 'trial and error' fails

by Martha Höhne, Leibniz Institute for Catalysis

In most industrial chemical reactions, catalysts combine with the starting materials and accompany them through intermediate stages to the product. In chemistry, this pathway is known as the reaction mechanism, and it is a kind of black box: nobody knows what is happening at the molecular level at first.

If the reaction result in the laboratory falls short of expectations, chemists first resort to trial and error. Put simply, they modify the reaction until it works. Sometimes, however, it is worth taking a closer look at the reaction mechanism , as Dr. Nora Jannsen at the Leibniz Institute for Catalysis in Rostock shows using a model reaction.

She recently published her findings, which she obtained as part of her doctorate, in the Journal of the American Chemical Society .

The model reaction sounds unspectacular and, above all, strange to the layman's ear, explains Jannsen. "Benzotriazole, usually a corrosion inhibitor, is converted into a new substance with an allene (the emphasis here is on the second syllable) using a rhodium catalyst ." This is then called allylbenzotriazole and can be used in a variety of syntheses. The reaction was developed by a research group led by Prof. Breit at the University of Freiburg.

Functional group set precisely

The colleagues in Freiburg succeeded in precisely linking a " functional group " to a very specific position in benzotrialzole. This is where a nitrogen–hydrogen bond (N–H) is located, as Jannsen explains.

"Functional groups" are important as molecular segments because they are responsible for the specific, e.g., pharmaceutical, effect.

"The Freiburg team wanted to place such a group in benzotriazole exactly where the N–H bond is, and the N–H bond has to give way for this," Jannsen continues. The colleagues managed to do this. "But they didn't understand on what basis they had achieved this."

That is unfortunate. Because only with an understanding of the molecular events can the reaction be specifically applied and optimized in the future. This was the aim of Jannsen's dissertation, which she successfully defended in Rostock in 2023.

Idea: Catalyst breaks bond

So how does such a reaction work? The start and end are known. What is also known about this reaction is that every single atom from the starting materials is later found in the product; chemists call this an "atom-economic" reaction. This means that in the course of the reaction, the hydrogen from the N–H bond must pass from the benzotriazole to the second starting material, the allene.

Jannsen says, "The Freiburg scientists thought that the catalyst breaks the nitrogen–hydrogen bond, i.e., a so-called oxidative addition of the benzotriazole takes place. Rhodium catalysts are known for this type of reaction."

Jannsen tested the idea by first reacting the rhodium catalyst with only one starting material, benzotriazole. She isolated samples from this reaction for nuclear magnetic resonance spectroscopy (NMR) and X-ray crystal structure analysis. The result: "The N–H bond is not broken at all. The benzotriazole remains completely intact, it only attaches itself to the catalyst."

Result: Simple coordination

The chemist then discovered that the second starting substance, allen, also binds to the catalyst. And this is where the following happens: "The two starting materials come into direct contact with each other, and the benzotriazole transfers the hydrogen atom, also known as the proton, to the allene. The catalyst merely holds the starting materials in place, but does not intervene directly in this step."

Jannsen then substantiated this proposal in detail using quantum mechanics , i.e., by theoretically modeling the reaction pathway.

Jannsen was surprised that the catalyst managed the whole thing so simply. For laypeople, it may sound a bit like a chemical rope trick. In technical terms, such a process is well known and is called protonation.

This process had an advantage. Jannsen says, "Interestingly, the reaction conditions for protonation can be significantly improved by adding another proton source." For example, she succeeded in reducing the reaction temperature from 80°C to room temperature by adding a type of co-catalyst.

A lot does not always help a lot

Jannsen also discovered that the benzotriazole can also block the catalyst under certain circumstances. This is the case when this starting substance occupies the catalyst twice, so that its reaction partner, the allen, cannot find a free space on the catalyst.

This paralyzes the catalytic activity and leads to the catalyst being "consumed." "It probably helps here to simply add the starting material to the reaction successively so that the catalyst comes into less contact with it," Jannsen says.

Journal information: Journal of the American Chemical Society

Provided by Leibniz Institute for Catalysis

Explore further

Feedback to editors

Managing meandering waterways in a changing world

13 hours ago

New dataset sheds light on relationship of far-red sun-induced chlorophyll fluorescence to canopy-level photosynthesis

How much trust do people have in different types of scientists?

14 hours ago

Scientists say voluntary corporate emissions targets not enough to create real climate action

Barley plants fine-tune their root microbial communities through sugary secretions

A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins

Yeast study offers possible answer to why some species are generalists and others specialists

Cichlid fishes' curiosity promotes biodiversity: How exploratory behavior aids in ecological adaptation

Climate change could become the main driver of biodiversity decline by mid-century, analysis suggests

First-of-its-kind study shows that conservation actions are effective at halting and reversing biodiversity loss

Relevant physicsforums posts, ideas for a project in computational chemistry.

16 hours ago

Very confused about Naunyn definition of acid and base

Apr 24, 2024

Can you eat the Periodic Table?

Apr 23, 2024

New Insight into the Chemistry of Solvents

Apr 17, 2024

Separation of KCl from potassium chromium(III) PDTA

Apr 16, 2024

Zirconium Versus Zirconium Carbide For Use With Galinstan

Mar 29, 2024

More from Chemistry

Related Stories

Magnetism boosts hydrogen production in model catalysts

Research team develops catalyst that can purify municipal sewage while enhancing hydrogen generation efficiency

Mar 13, 2024

New technique developed for measurement of temperature distribution inside single catalyst particle

Mar 5, 2024

Applying green chemistry principles to iron catalysis

Feb 19, 2024

Researchers realize ethylene methoxycarbonylation reaction over single-atom catalyst

Jan 16, 2024

Material cycle for amine chemistry: Important building blocks created from platform chemical in single step

Oct 11, 2023

Recommended for you

Freeze casting—a guide to creating hierarchically structured materials

The secret to saving old books could be gluten-free glues

17 hours ago

Synthesis of two new carbides provides perspective on how complex carbon structures could exist on other planets

Scientists discover method to prevent coalescence in immiscible liquids

20 hours ago

Synthetic droplets cause a stir in the primordial soup: Chemotaxis research answers questions about biological movement

18 hours ago

Let us know if there is a problem with our content

Use this form if you have come across a typo, inaccuracy or would like to send an edit request for the content on this page. For general inquiries, please use our contact form . For general feedback, use the public comments section below (please adhere to guidelines ).

Please select the most appropriate category to facilitate processing of your request

Thank you for taking time to provide your feedback to the editors.

Your feedback is important to us. However, we do not guarantee individual replies due to the high volume of messages.

E-mail the story

Your email address is used only to let the recipient know who sent the email. Neither your address nor the recipient's address will be used for any other purpose. The information you enter will appear in your e-mail message and is not retained by Phys.org in any form.

Newsletter sign up

Get weekly and/or daily updates delivered to your inbox. You can unsubscribe at any time and we'll never share your details to third parties.

More information Privacy policy

Donate and enjoy an ad-free experience

We keep our content available to everyone. Consider supporting Science X's mission by getting a premium account.

E-mail newsletter

Suggestions or feedback?

MIT News | Massachusetts Institute of Technology

• Machine learning
• Social justice
• Black holes
• Classes and programs

Departments

• Aeronautics and Astronautics
• Brain and Cognitive Sciences
• Architecture
• Political Science
• Mechanical Engineering

Centers, Labs, & Programs

• Abdul Latif Jameel Poverty Action Lab (J-PAL)
• Picower Institute for Learning and Memory
• Lincoln Laboratory
• School of Architecture + Planning
• School of Engineering
• School of Humanities, Arts, and Social Sciences
• Sloan School of Management
• School of Science
• MIT Schwarzman College of Computing

Researchers detect a new molecule in space

Press contact :.

Previous image Next image

New research from the group of MIT Professor Brett McGuire has revealed the presence of a previously unknown molecule in space. The team's open-access paper, “ Rotational Spectrum and First Interstellar Detection of 2-Methoxyethanol Using ALMA Observations of NGC 6334I ,” appears in April 12 issue of The Astrophysical Journal Letters .

Zachary T.P. Fried , a graduate student in the McGuire group and the lead author of the publication, worked to assemble a puzzle comprised of pieces collected from across the globe, extending beyond MIT to France, Florida, Virginia, and Copenhagen, to achieve this exciting discovery. 

“Our group tries to understand what molecules are present in regions of space where stars and solar systems will eventually take shape,” explains Fried. “This allows us to piece together how chemistry evolves alongside the process of star and planet formation. We do this by looking at the rotational spectra of molecules, the unique patterns of light they give off as they tumble end-over-end in space. These patterns are fingerprints (barcodes) for molecules. To detect new molecules in space, we first must have an idea of what molecule we want to look for, then we can record its spectrum in the lab here on Earth, and then finally we look for that spectrum in space using telescopes.”

Searching for molecules in space

The McGuire Group has recently begun to utilize machine learning to suggest good target molecules to search for. In 2023, one of these machine learning models suggested the researchers target a molecule known as 2-methoxyethanol. 

“There are a number of 'methoxy' molecules in space, like dimethyl ether, methoxymethanol, ethyl methyl ether, and methyl formate, but 2-methoxyethanol would be the largest and most complex ever seen,” says Fried. To detect this molecule using radiotelescope observations, the group first needed to measure and analyze its rotational spectrum on Earth. The researchers combined experiments from the University of Lille (Lille, France), the New College of Florida (Sarasota, Florida), and the McGuire lab at MIT to measure this spectrum over a broadband region of frequencies ranging from the microwave to sub-millimeter wave regimes (approximately 8 to 500 gigahertz). 

The data gleaned from these measurements permitted a search for the molecule using Atacama Large Millimeter/submillimeter Array (ALMA) observations toward two separate star-forming regions: NGC 6334I and IRAS 16293-2422B. Members of the McGuire group analyzed these telescope observations alongside researchers at the National Radio Astronomy Observatory (Charlottesville, Virginia) and the University of Copenhagen, Denmark. 

“Ultimately, we observed 25 rotational lines of 2-methoxyethanol that lined up with the molecular signal observed toward NGC 6334I (the barcode matched!), thus resulting in a secure detection of 2-methoxyethanol in this source,” says Fried. “This allowed us to then derive physical parameters of the molecule toward NGC 6334I, such as its abundance and excitation temperature. It also enabled an investigation of the possible chemical formation pathways from known interstellar precursors.”

Looking forward

Molecular discoveries like this one help the researchers to better understand the development of molecular complexity in space during the star formation process. 2-methoxyethanol, which contains 13 atoms, is quite large for interstellar standards — as of 2021, only six species larger than 13 atoms were detected outside the solar system , many by McGuire’s group, and all of them existing as ringed structures.  

“Continued observations of large molecules and subsequent derivations of their abundances allows us to advance our knowledge of how efficiently large molecules can form and by which specific reactions they may be produced,” says Fried. “Additionally, since we detected this molecule in NGC 6334I but not in IRAS 16293-2422B, we were presented with a unique opportunity to look into how the differing physical conditions of these two sources may be affecting the chemistry that can occur.”

Share this news article on:

Related links.

• McGuire Lab
• Department of Chemistry

Related Topics

• Space, astronomy and planetary science
• Astrophysics

Related Articles

Found in space: Complex carbon-based molecules

Previous item Next item

More MIT News

Two from MIT awarded 2024 Paul and Daisy Soros Fellowships for New Americans

Read full story →

MIT Emerging Talent opens pathways for underserved global learners

The MIT Edgerton Center’s third annual showcase dazzles onlookers

3 Questions: A shared vocabulary for how infectious diseases spread

Seven from MIT elected to American Academy of Arts and Sciences for 2024

Two MIT teams selected for NSF sustainable materials grants

• More news on MIT News homepage →

Massachusetts Institute of Technology 77 Massachusetts Avenue, Cambridge, MA, USA

• Map (opens in new window)
• Events (opens in new window)
• People (opens in new window)
• Careers (opens in new window)
• Accessibility
• Social Media Hub
• MIT on Facebook
• MIT on YouTube
• MIT on Instagram

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

• View all journals

Medicinal chemistry articles from across Nature Portfolio

Medicinal chemistry deals with the design, optimization and development of chemical compounds for use as drugs. It is inherently a multidisciplinary topic — beginning with the synthesis of potential drugs followed by studies investigating their interactions with biological targets to understand the medicinal effects of the drug, its metabolism and side-effects.

Related Subjects

• Chemical libraries
• Cheminformatics
• Computational chemistry
• Drug delivery
• Drug discovery and development
• Lead optimization
• Pharmacology
• Structure-based drug design
• Target identification
• Target validation

Latest Research and Reviews

Benastatin K, a chlorinated benastatin-related antibiotic from Streptomyces sp. HGTA384

• Teppei Kawahara
• Kanako Saita
• Mikiyo Wada

Minimizing higher-order aggregation maximizes iron mobilization by small molecules

A small-molecule iron mobilizer, FeM-1269, minimally higher-order aggregates in aqueous media and effectively mobilizes iron across a range of concentrations. FeM-1269-promoted iron mobilization restores physiology in animals at well-tolerated doses.

• Andrew D. Blake
• Jianhua Chao
• Martin D. Burke

Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition

The differential effects of targeting individual domains of multidomain enzymatic proteins are generally poorly understood. Here, the authors demonstrate lineage-specific sensitivities to domain-specific inhibition of EP300/CBP proteins across cancer and link these effects in group 3 medulloblastoma to control of a transcriptional dependency network.

• Noha A. M. Shendy
• Melissa Bikowitz
• Adam D. Durbin

The antimicrobial fibupeptide lugdunin forms water-filled channel structures in lipid membranes

The fibupeptide lugdunin has shown activity against antibiotic-resistant bacteria. Here, authors disclose its mechanism of action in lipid membranes and demonstrate that it assembles into nanotubes facilitating the translocation of monovalent cations.

• Dominik Ruppelt
• Marius F. W. Trollmann
• Claudia Steinem

Synthesis and molecular docking studies of new aryl imeglimin derivatives as a potent antidiabetic agent in a diabetic zebrafish model

• Aylin Khodakhah
• Hassan Mohammadi
• Massoud Amanlou

Prospective de novo drug design with deep interactome learning

The use of data-driven generative models for drug design is challenging due to the scarcity of data. Here, the authors introduce a “zero-shot" generative deep model to enable the generation of molecules by both structure- and ligand-based drug design and apply it to design PPAR γ agonists with desired properties.

• Kenneth Atz
• Leandro Cotos
• Gisbert Schneider

News and Comment

Tying the knot with lysine

Targeted covalent inhibitors (TCIs) can react irreversibly with lysine in kinases and other proteins. Small molecule TCIs can have both broad or specific lysine targeting whereas peptide- and protein-based TCIs were shown to provide high target specificity for lysines in shallow protein surfaces.

• Ana Koperniku
• Nicholas A. Meanwell

Another KRAS variant trapped

Inhibitors of KRAS G12C have shown that directly targeting RAS is possible, but G12C is only one of many RAS driver mutations. Covalent targeting of another major variant, G12D, raises hope for treating other groups of patients with KRAS-mutant tumors.

• Kenneth Westover

The druggability of SH2 domains unmasked

Developing inhibitors for SH2 domains is challenging due to their shallow pockets and highly charged ligands. Structure-guided drug design has enabled the discovery of a cell-permeable covalent inhibitor of the SOCS2 SH2 domain, a key regulator of cytokine signaling pathways.

• Oliver Hantschel

A protein-templated selection approach for the identification of full ligands from DNA-encoded libraries

A protein-templated selection approach has been developed for the discovery of full ligands from dual-pharmacophore DNA-encoded libraries by incorporating fragment linking into the selection process. The performance of this method was demonstrated with selections against protein–protein interaction and protein–DNA interaction targets, through which potent and selective inhibitors were identified.

Redefining peptide therapeutics with semaglutide

Thomas Kruse and Søren Østergaard reflect on the development of the GLP-1 analogue, semaglutide, which is reshaping peptide therapeutics in type 2 diabetes, weight management, and beyond.

• Thomas Kruse
• Søren Østergaard

Design of a renal-sparing antifungal

• Susan J. Allison

Quick links

• Explore articles by subject
• Guide to authors
• Editorial policies

Pattern formation in the nano-cosmos

A new theory of elastic phase separation can help to control pattern formation on small scales.

A new model developed by scientists from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) extends the theory of elastic phase separation towards nanoscopic structures. Such patterns are frequent in biological systems and also used in nano-engineering to create structural color. With their new insights, the scientists can predict the length scale of nanoscopic patterns and thus control them during production.

Well-defined structural patterns are found all over the place in biological systems. A well-known example is the coloration of bird feathers and butterfly wings, which relies on the regular arrangement of nanoscopic structures, known as structural color. Such patterns often form by phase separation. Different components separate from each other, similarly to how oil separates from water. However, it remains unclear how nature creates well-defined patterns leading to such colors. Generally, manufacturing synthetic materials on this submicron length scale is a common challenge.

One way to control structures made by phase separation relies on elasticity: deformations of materials are well-described by elasticity theory on macroscopic scales, for example to explain how a piece of rubber deforms under the effect of force. However, on a nanoscopic scale, materials are not homogeneous anymore and the macroscopic description of the material is insufficient. Instead, the actual arrangement of molecules matters. Moreover, deforming any material requires energy, which thus impedes large deformations. Individual droplets formed by phase separation can thus not grow indefinitely. Depending on their arrangement, a regular pattern can emerge.

Scientists around David Zwicker, head of the Max Planck Research Group "Theory of Biological Fluids" at MPI-DS, now developed a model to address this aspect. They proposed a theory based on nonlocal elasticity to predict pattern formation by phase separation. "With our new model, we can now take into account the relevant additional aspect to describe the system," Zwicker says. "Modelling all molecular components in atomic detail would exceed the computational power. Instead, we extended the existing theory towards smaller structures comparable to the mesh size," he explains.

The new theory predicts how material properties affect the formed pattern. It can thus help engineers to create specific nanoscopic structures, following physical principles of self-organization that nature exploits.

• Materials Science
• Civil Engineering
• Engineering and Construction
• Albert Einstein
• Nanotechnology
• Engineering
• Construction
• Civil engineering
• Scale model
• Tensile strength
• Airbus A380
• Introduction to quantum mechanics
• Security engineering
• Three-phase electric power

Story Source:

Materials provided by Max Planck Institute for Dynamics and Self-Organization . Note: Content may be edited for style and length.

Journal Reference :

• Yicheng Qiang, Chengjie Luo, David Zwicker. Nonlocal Elasticity Yields Equilibrium Patterns in Phase Separating Systems . Physical Review X , 2024; 14 (2) DOI: 10.1103/PhysRevX.14.021009

Cite This Page :

Explore More

• Food in Sight? The Liver Is Ready!
• Acid Reflux Drugs and Risk of Migraine
• Do Cells Have a Hidden Communication System?
• Mice Given Mouse-Rat Brains Can Smell Again
• How Do Birds Flock? New Aerodynamics
• Cancer: Epigenetic Origin Without DNA Mutation
• Climate Change Driving Biodiversity Loss
• Why Can't Robots Outrun Animals?
• Evolution of Gliding in Marsupials
• Novel One-Dimensional Superconductor

Trending Topics

Strange & offbeat.