example of research questions in experimental research

Research Question Examples 🧑🏻‍🏫

25+ Practical Examples & Ideas To Help You Get Started 

By: Derek Jansen (MBA) | October 2023

A well-crafted research question (or set of questions) sets the stage for a robust study and meaningful insights.  But, if you’re new to research, it’s not always clear what exactly constitutes a good research question. In this post, we’ll provide you with clear examples of quality research questions across various disciplines, so that you can approach your research project with confidence!

Research Question Examples

• Psychology research questions
• Business research questions
• Education research questions
• Healthcare research questions
• Computer science research questions

Examples: Psychology

Let’s start by looking at some examples of research questions that you might encounter within the discipline of psychology.

How does sleep quality affect academic performance in university students?

This question is specific to a population (university students) and looks at a direct relationship between sleep and academic performance, both of which are quantifiable and measurable variables.

What factors contribute to the onset of anxiety disorders in adolescents?

The question narrows down the age group and focuses on identifying multiple contributing factors. There are various ways in which it could be approached from a methodological standpoint, including both qualitatively and quantitatively.

Do mindfulness techniques improve emotional well-being?

This is a focused research question aiming to evaluate the effectiveness of a specific intervention.

How does early childhood trauma impact adult relationships?

This research question targets a clear cause-and-effect relationship over a long timescale, making it focused but comprehensive.

Is there a correlation between screen time and depression in teenagers?

This research question focuses on an in-demand current issue and a specific demographic, allowing for a focused investigation. The key variables are clearly stated within the question and can be measured and analysed (i.e., high feasibility).

Examples: Business/Management

Next, let’s look at some examples of well-articulated research questions within the business and management realm.

How do leadership styles impact employee retention?

This is an example of a strong research question because it directly looks at the effect of one variable (leadership styles) on another (employee retention), allowing from a strongly aligned methodological approach.

What role does corporate social responsibility play in consumer choice?

Current and precise, this research question can reveal how social concerns are influencing buying behaviour by way of a qualitative exploration.

Does remote work increase or decrease productivity in tech companies?

Focused on a particular industry and a hot topic, this research question could yield timely, actionable insights that would have high practical value in the real world.

How do economic downturns affect small businesses in the homebuilding industry?

Vital for policy-making, this highly specific research question aims to uncover the challenges faced by small businesses within a certain industry.

Which employee benefits have the greatest impact on job satisfaction?

By being straightforward and specific, answering this research question could provide tangible insights to employers.

Examples: Education

Next, let’s look at some potential research questions within the education, training and development domain.

How does class size affect students’ academic performance in primary schools?

This example research question targets two clearly defined variables, which can be measured and analysed relatively easily.

Do online courses result in better retention of material than traditional courses?

Timely, specific and focused, answering this research question can help inform educational policy and personal choices about learning formats.

What impact do US public school lunches have on student health?

Targeting a specific, well-defined context, the research could lead to direct changes in public health policies.

To what degree does parental involvement improve academic outcomes in secondary education in the Midwest?

This research question focuses on a specific context (secondary education in the Midwest) and has clearly defined constructs.

What are the negative effects of standardised tests on student learning within Oklahoma primary schools?

This research question has a clear focus (negative outcomes) and is narrowed into a very specific context.

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Examples: Healthcare

Shifting to a different field, let’s look at some examples of research questions within the healthcare space.

What are the most effective treatments for chronic back pain amongst UK senior males?

Specific and solution-oriented, this research question focuses on clear variables and a well-defined context (senior males within the UK).

How do different healthcare policies affect patient satisfaction in public hospitals in South Africa?

This question is has clearly defined variables and is narrowly focused in terms of context.

Which factors contribute to obesity rates in urban areas within California?

This question is focused yet broad, aiming to reveal several contributing factors for targeted interventions.

Does telemedicine provide the same perceived quality of care as in-person visits for diabetes patients?

Ideal for a qualitative study, this research question explores a single construct (perceived quality of care) within a well-defined sample (diabetes patients).

Which lifestyle factors have the greatest affect on the risk of heart disease?

This research question aims to uncover modifiable factors, offering preventive health recommendations.

Examples: Computer Science

Last but certainly not least, let’s look at a few examples of research questions within the computer science world.

What are the perceived risks of cloud-based storage systems?

Highly relevant in our digital age, this research question would align well with a qualitative interview approach to better understand what users feel the key risks of cloud storage are.

Which factors affect the energy efficiency of data centres in Ohio?

With a clear focus, this research question lays a firm foundation for a quantitative study.

How do TikTok algorithms impact user behaviour amongst new graduates?

While this research question is more open-ended, it could form the basis for a qualitative investigation.

What are the perceived risk and benefits of open-source software software within the web design industry?

Practical and straightforward, the results could guide both developers and end-users in their choices.

Remember, these are just examples…

In this post, we’ve tried to provide a wide range of research question examples to help you get a feel for what research questions look like in practice. That said, it’s important to remember that these are just examples and don’t necessarily equate to good research topics . If you’re still trying to find a topic, check out our topic megalist for inspiration.

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Educational resources and simple solutions for your research journey

How to Craft a Strong Research Question (With Research Question Examples)

A sound and effective research question is a key element that must be identified and pinned down before researchers can even begin their research study or work. A strong research question lays the foundation for your entire study, guiding your investigation and shaping your findings. Hence, it is critical that researchers spend considerable time assessing and refining the research question based on in-depth reading and comprehensive literature review. In this article, we will discuss how to write a strong research question and provide you with some good examples of research questions across various disciplines.

Table of Contents

The importance of a research question

A research question plays a crucial role in driving scientific inquiry, setting the direction and purpose of your study, and guiding your entire research process. By formulating a clear and focused research question, you lay the foundation for your investigation, ensuring that your research remains on track and aligned with your objectives so you can make meaningful contribution to the existing body of knowledge. A well-crafted research question also helps you define the scope of your study and identify the appropriate methodologies and data collection techniques to employ.

Key components of a strong research question

A good research question possesses several key components that contribute to the quality and impact of your study. Apart from providing a clear framework to generate meaningful results, a well-defined research question allows other researchers to understand the purpose and significance of your work. So, when working on your research question, incorporate the following elements:

• Specificity : A strong research question should be specific about the main focus of your study, enabling you to gather precise data and draw accurate conclusions. It clearly defines the variables, participants, and context involved, leaving no room for ambiguity.
• Clarity : A good research question is clear and easily understood, so articulate the purpose and intent of your study concisely without being generic or vague. Ensuring clarity in your research question helps both you and your readers grasp the research objective.
• Feasibility : While crafting a research question, consider the practicality of conducting the research and availability of necessary data or access to participants. Think whether your study is realistic and achievable within the constraints of time, resources, and ethical considerations.

How to craft a well-defined research question

A first step that will help save time and effort is knowing what your aims are and thinking about a few problem statements on the area or aspect one wants to study or do research on. Contemplating these statements as one undertakes more progressive reading can help the researcher in reassessing and fine-tuning the research question. This can be done over time as they read and learn more about the research topic, along with a broad literature review and parallel discussions with peer researchers and supervisors. In some cases, a researcher can have more than one research question if the research being undertaken is a PhD thesis or dissertation, but try not to cover multiple concerns on a topic.

A strong research question must be researchable, original, complex, and relevant. Here are five simple steps that can make the entire process easier.

• Identify a broad topic from your areas of interest, something that is relevant, and you are passionate about since you’ll be spending a lot of time conducting your research.
• Do a thorough literature review to weed out potential gaps in research and stay updated on what’s currently being done in your chosen topic and subject area.
• Shortlist possible research questions based on the research gaps or see how you can build on or refute previously published ideas and concepts.
• Assess your chosen research question using the FINER criteria that helps you evaluate whether the research is Feasible, Interesting, Novel, Ethical, and Relevant. 1
• Formulate the final research question, while ensuring it is clear, well-written, and addresses all the key elements of a strong research question.

Examples of research questions

Remember to adapt your research question to suit your purpose, whether it’s exploratory, descriptive, comparative, experimental, qualitative, or quantitative. Embrace the iterative nature of the research process, continually evaluating and refining your question as you progress. Here are some good examples of research questions across various disciplines.

Exploratory research question examples

• How does social media impact interpersonal relationships among teenagers?
• What are the potential benefits of incorporating mindfulness practices in the workplace?

Descriptive research question examples

• What factors influence customer loyalty in the e-commerce industry?
• Is there a relationship between socioeconomic status and academic performance among elementary school students?

Comparative research question examples

• How does the effectiveness of traditional teaching methods compare to online learning platforms in mathematics education?
• What is the impact of different healthcare policies on patient outcomes in various countries?

Experimental research question examples

• What are the effects of a new drug on reducing symptoms of a specific medical condition?
• Does a dietary intervention have an impact on weight loss among individuals with obesity?

Qualitative research question examples

• What are the lived experiences of immigrants adapting to a new culture?
• What factors influence job satisfaction among healthcare professionals?

Quantitative research question examples

• Is there a relationship between sleep duration and academic performance among college students?
• How effective is a specific intervention in reducing anxiety levels among individuals with phobias?

With these simple guidelines and inspiring examples of research questions, you are equipped to embark on your research journey with confidence and purpose. Here’s wishing you all the best for your future endeavors!

References:

• How to write a research question: Steps and examples. Indeed Career Guide. Available online at https://www.indeed.com/career-advice/career-development/how-to-write-research-questions

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Methodology

• Guide to Experimental Design | Overview, Steps, & Examples

Guide to Experimental Design | Overview, 5 steps & Examples

Published on December 3, 2019 by Rebecca Bevans . Revised on June 21, 2023.

Experiments are used to study causal relationships . You manipulate one or more independent variables and measure their effect on one or more dependent variables.

Experimental design create a set of procedures to systematically test a hypothesis . A good experimental design requires a strong understanding of the system you are studying.

There are five key steps in designing an experiment:

• Consider your variables and how they are related
• Write a specific, testable hypothesis
• Design experimental treatments to manipulate your independent variable
• Assign subjects to groups, either between-subjects or within-subjects
• Plan how you will measure your dependent variable

For valid conclusions, you also need to select a representative sample and control any  extraneous variables that might influence your results. If random assignment of participants to control and treatment groups is impossible, unethical, or highly difficult, consider an observational study instead. This minimizes several types of research bias, particularly sampling bias , survivorship bias , and attrition bias as time passes.

Table of contents

Step 1: define your variables, step 2: write your hypothesis, step 3: design your experimental treatments, step 4: assign your subjects to treatment groups, step 5: measure your dependent variable, other interesting articles, frequently asked questions about experiments.

You should begin with a specific research question . We will work with two research question examples, one from health sciences and one from ecology:

To translate your research question into an experimental hypothesis, you need to define the main variables and make predictions about how they are related.

Start by simply listing the independent and dependent variables .

Then you need to think about possible extraneous and confounding variables and consider how you might control  them in your experiment.

Finally, you can put these variables together into a diagram. Use arrows to show the possible relationships between variables and include signs to show the expected direction of the relationships.

Here we predict that increasing temperature will increase soil respiration and decrease soil moisture, while decreasing soil moisture will lead to decreased soil respiration.

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Now that you have a strong conceptual understanding of the system you are studying, you should be able to write a specific, testable hypothesis that addresses your research question.

The next steps will describe how to design a controlled experiment . In a controlled experiment, you must be able to:

• Systematically and precisely manipulate the independent variable(s).
• Precisely measure the dependent variable(s).
• Control any potential confounding variables.

If your study system doesn’t match these criteria, there are other types of research you can use to answer your research question.

How you manipulate the independent variable can affect the experiment’s external validity – that is, the extent to which the results can be generalized and applied to the broader world.

First, you may need to decide how widely to vary your independent variable.

• just slightly above the natural range for your study region.
• over a wider range of temperatures to mimic future warming.
• over an extreme range that is beyond any possible natural variation.

Second, you may need to choose how finely to vary your independent variable. Sometimes this choice is made for you by your experimental system, but often you will need to decide, and this will affect how much you can infer from your results.

• a categorical variable : either as binary (yes/no) or as levels of a factor (no phone use, low phone use, high phone use).
• a continuous variable (minutes of phone use measured every night).

How you apply your experimental treatments to your test subjects is crucial for obtaining valid and reliable results.

First, you need to consider the study size : how many individuals will be included in the experiment? In general, the more subjects you include, the greater your experiment’s statistical power , which determines how much confidence you can have in your results.

Then you need to randomly assign your subjects to treatment groups . Each group receives a different level of the treatment (e.g. no phone use, low phone use, high phone use).

You should also include a control group , which receives no treatment. The control group tells us what would have happened to your test subjects without any experimental intervention.

When assigning your subjects to groups, there are two main choices you need to make:

• A completely randomized design vs a randomized block design .
• A between-subjects design vs a within-subjects design .

Randomization

An experiment can be completely randomized or randomized within blocks (aka strata):

• In a completely randomized design , every subject is assigned to a treatment group at random.
• In a randomized block design (aka stratified random design), subjects are first grouped according to a characteristic they share, and then randomly assigned to treatments within those groups.

Sometimes randomization isn’t practical or ethical , so researchers create partially-random or even non-random designs. An experimental design where treatments aren’t randomly assigned is called a quasi-experimental design .

Between-subjects vs. within-subjects

In a between-subjects design (also known as an independent measures design or classic ANOVA design), individuals receive only one of the possible levels of an experimental treatment.

In medical or social research, you might also use matched pairs within your between-subjects design to make sure that each treatment group contains the same variety of test subjects in the same proportions.

In a within-subjects design (also known as a repeated measures design), every individual receives each of the experimental treatments consecutively, and their responses to each treatment are measured.

Within-subjects or repeated measures can also refer to an experimental design where an effect emerges over time, and individual responses are measured over time in order to measure this effect as it emerges.

Counterbalancing (randomizing or reversing the order of treatments among subjects) is often used in within-subjects designs to ensure that the order of treatment application doesn’t influence the results of the experiment.

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Finally, you need to decide how you’ll collect data on your dependent variable outcomes. You should aim for reliable and valid measurements that minimize research bias or error.

Some variables, like temperature, can be objectively measured with scientific instruments. Others may need to be operationalized to turn them into measurable observations.

• Ask participants to record what time they go to sleep and get up each day.
• Ask participants to wear a sleep tracker.

How precisely you measure your dependent variable also affects the kinds of statistical analysis you can use on your data.

Experiments are always context-dependent, and a good experimental design will take into account all of the unique considerations of your study system to produce information that is both valid and relevant to your research question.

If you want to know more about statistics , methodology , or research bias , make sure to check out some of our other articles with explanations and examples.

• Student’s  t -distribution
• Normal distribution
• Null and Alternative Hypotheses
• Chi square tests
• Confidence interval
• Cluster sampling
• Stratified sampling
• Data cleansing
• Reproducibility vs Replicability
• Peer review
• Likert scale

Research bias

• Implicit bias
• Framing effect
• Cognitive bias
• Placebo effect
• Hawthorne effect
• Hindsight bias
• Affect heuristic

Experimental design means planning a set of procedures to investigate a relationship between variables . To design a controlled experiment, you need:

• A testable hypothesis
• At least one independent variable that can be precisely manipulated
• At least one dependent variable that can be precisely measured

When designing the experiment, you decide:

• How you will manipulate the variable(s)
• How you will control for any potential confounding variables
• How many subjects or samples will be included in the study
• How subjects will be assigned to treatment levels

Experimental design is essential to the internal and external validity of your experiment.

The key difference between observational studies and experimental designs is that a well-done observational study does not influence the responses of participants, while experiments do have some sort of treatment condition applied to at least some participants by random assignment .

A confounding variable , also called a confounder or confounding factor, is a third variable in a study examining a potential cause-and-effect relationship.

A confounding variable is related to both the supposed cause and the supposed effect of the study. It can be difficult to separate the true effect of the independent variable from the effect of the confounding variable.

In your research design , it’s important to identify potential confounding variables and plan how you will reduce their impact.

In a between-subjects design , every participant experiences only one condition, and researchers assess group differences between participants in various conditions.

In a within-subjects design , each participant experiences all conditions, and researchers test the same participants repeatedly for differences between conditions.

The word “between” means that you’re comparing different conditions between groups, while the word “within” means you’re comparing different conditions within the same group.

An experimental group, also known as a treatment group, receives the treatment whose effect researchers wish to study, whereas a control group does not. They should be identical in all other ways.

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Bevans, R. (2023, June 21). Guide to Experimental Design | Overview, 5 steps & Examples. Scribbr. Retrieved June 18, 2024, from https://www.scribbr.com/methodology/experimental-design/

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• Methodology
• A Quick Guide to Experimental Design | 5 Steps & Examples

A Quick Guide to Experimental Design | 5 Steps & Examples

Published on 11 April 2022 by Rebecca Bevans . Revised on 5 December 2022.

Experiments are used to study causal relationships . You manipulate one or more independent variables and measure their effect on one or more dependent variables.

Experimental design means creating a set of procedures to systematically test a hypothesis . A good experimental design requires a strong understanding of the system you are studying. 

There are five key steps in designing an experiment:

• Consider your variables and how they are related
• Write a specific, testable hypothesis
• Design experimental treatments to manipulate your independent variable
• Assign subjects to groups, either between-subjects or within-subjects
• Plan how you will measure your dependent variable

For valid conclusions, you also need to select a representative sample and control any  extraneous variables that might influence your results. If if random assignment of participants to control and treatment groups is impossible, unethical, or highly difficult, consider an observational study instead.

Table of contents

Step 1: define your variables, step 2: write your hypothesis, step 3: design your experimental treatments, step 4: assign your subjects to treatment groups, step 5: measure your dependent variable, frequently asked questions about experimental design.

You should begin with a specific research question . We will work with two research question examples, one from health sciences and one from ecology:

To translate your research question into an experimental hypothesis, you need to define the main variables and make predictions about how they are related.

Start by simply listing the independent and dependent variables .

Then you need to think about possible extraneous and confounding variables and consider how you might control  them in your experiment.

Finally, you can put these variables together into a diagram. Use arrows to show the possible relationships between variables and include signs to show the expected direction of the relationships.

Here we predict that increasing temperature will increase soil respiration and decrease soil moisture, while decreasing soil moisture will lead to decreased soil respiration.

Prevent plagiarism, run a free check.

Now that you have a strong conceptual understanding of the system you are studying, you should be able to write a specific, testable hypothesis that addresses your research question.

The next steps will describe how to design a controlled experiment . In a controlled experiment, you must be able to:

• Systematically and precisely manipulate the independent variable(s).
• Precisely measure the dependent variable(s).
• Control any potential confounding variables.

If your study system doesn’t match these criteria, there are other types of research you can use to answer your research question.

How you manipulate the independent variable can affect the experiment’s external validity – that is, the extent to which the results can be generalised and applied to the broader world.

First, you may need to decide how widely to vary your independent variable.

• just slightly above the natural range for your study region.
• over a wider range of temperatures to mimic future warming.
• over an extreme range that is beyond any possible natural variation.

Second, you may need to choose how finely to vary your independent variable. Sometimes this choice is made for you by your experimental system, but often you will need to decide, and this will affect how much you can infer from your results.

• a categorical variable : either as binary (yes/no) or as levels of a factor (no phone use, low phone use, high phone use).
• a continuous variable (minutes of phone use measured every night).

How you apply your experimental treatments to your test subjects is crucial for obtaining valid and reliable results.

First, you need to consider the study size : how many individuals will be included in the experiment? In general, the more subjects you include, the greater your experiment’s statistical power , which determines how much confidence you can have in your results.

Then you need to randomly assign your subjects to treatment groups . Each group receives a different level of the treatment (e.g. no phone use, low phone use, high phone use).

You should also include a control group , which receives no treatment. The control group tells us what would have happened to your test subjects without any experimental intervention.

When assigning your subjects to groups, there are two main choices you need to make:

• A completely randomised design vs a randomised block design .
• A between-subjects design vs a within-subjects design .

Randomisation

An experiment can be completely randomised or randomised within blocks (aka strata):

• In a completely randomised design , every subject is assigned to a treatment group at random.
• In a randomised block design (aka stratified random design), subjects are first grouped according to a characteristic they share, and then randomly assigned to treatments within those groups.

Sometimes randomisation isn’t practical or ethical , so researchers create partially-random or even non-random designs. An experimental design where treatments aren’t randomly assigned is called a quasi-experimental design .

Between-subjects vs within-subjects

In a between-subjects design (also known as an independent measures design or classic ANOVA design), individuals receive only one of the possible levels of an experimental treatment.

In medical or social research, you might also use matched pairs within your between-subjects design to make sure that each treatment group contains the same variety of test subjects in the same proportions.

In a within-subjects design (also known as a repeated measures design), every individual receives each of the experimental treatments consecutively, and their responses to each treatment are measured.

Within-subjects or repeated measures can also refer to an experimental design where an effect emerges over time, and individual responses are measured over time in order to measure this effect as it emerges.

Counterbalancing (randomising or reversing the order of treatments among subjects) is often used in within-subjects designs to ensure that the order of treatment application doesn’t influence the results of the experiment.

Finally, you need to decide how you’ll collect data on your dependent variable outcomes. You should aim for reliable and valid measurements that minimise bias or error.

Some variables, like temperature, can be objectively measured with scientific instruments. Others may need to be operationalised to turn them into measurable observations.

• Ask participants to record what time they go to sleep and get up each day.
• Ask participants to wear a sleep tracker.

How precisely you measure your dependent variable also affects the kinds of statistical analysis you can use on your data.

Experiments are always context-dependent, and a good experimental design will take into account all of the unique considerations of your study system to produce information that is both valid and relevant to your research question.

Experimental designs are a set of procedures that you plan in order to examine the relationship between variables that interest you.

To design a successful experiment, first identify:

• A testable hypothesis
• One or more independent variables that you will manipulate
• One or more dependent variables that you will measure

When designing the experiment, first decide:

• How your variable(s) will be manipulated
• How you will control for any potential confounding or lurking variables
• How many subjects you will include
• How you will assign treatments to your subjects

The key difference between observational studies and experiments is that, done correctly, an observational study will never influence the responses or behaviours of participants. Experimental designs will have a treatment condition applied to at least a portion of participants.

A confounding variable , also called a confounder or confounding factor, is a third variable in a study examining a potential cause-and-effect relationship.

A confounding variable is related to both the supposed cause and the supposed effect of the study. It can be difficult to separate the true effect of the independent variable from the effect of the confounding variable.

In your research design , it’s important to identify potential confounding variables and plan how you will reduce their impact.

In a between-subjects design , every participant experiences only one condition, and researchers assess group differences between participants in various conditions.

In a within-subjects design , each participant experiences all conditions, and researchers test the same participants repeatedly for differences between conditions.

The word ‘between’ means that you’re comparing different conditions between groups, while the word ‘within’ means you’re comparing different conditions within the same group.

Cite this Scribbr article

If you want to cite this source, you can copy and paste the citation or click the ‘Cite this Scribbr article’ button to automatically add the citation to our free Reference Generator.

Bevans, R. (2022, December 05). A Quick Guide to Experimental Design | 5 Steps & Examples. Scribbr. Retrieved 18 June 2024, from https://www.scribbr.co.uk/research-methods/guide-to-experimental-design/

Is this article helpful?

Rebecca Bevans

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Home Market Research

Experimental Research: What it is + Types of designs

Any research conducted under scientifically acceptable conditions uses experimental methods. The success of experimental studies hinges on researchers confirming the change of a variable is based solely on the manipulation of the constant variable. The research should establish a notable cause and effect.

What is Experimental Research?

Experimental research is a study conducted with a scientific approach using two sets of variables. The first set acts as a constant, which you use to measure the differences of the second set. Quantitative research methods , for example, are experimental.

If you don’t have enough data to support your decisions, you must first determine the facts. This research gathers the data necessary to help you make better decisions.

You can conduct experimental research in the following situations:

• Time is a vital factor in establishing a relationship between cause and effect.
• Invariable behavior between cause and effect.
• You wish to understand the importance of cause and effect.

Experimental Research Design Types

The classic experimental design definition is: “The methods used to collect data in experimental studies.”

There are three primary types of experimental design:

• Pre-experimental research design
• True experimental research design
• Quasi-experimental research design

The way you classify research subjects based on conditions or groups determines the type of research design  you should use.

0 1. Pre-Experimental Design

A group, or various groups, are kept under observation after implementing cause and effect factors. You’ll conduct this research to understand whether further investigation is necessary for these particular groups.

You can break down pre-experimental research further into three types:

• One-shot Case Study Research Design
• One-group Pretest-posttest Research Design
• Static-group Comparison

0 2. True Experimental Design

It relies on statistical analysis to prove or disprove a hypothesis, making it the most accurate form of research. Of the types of experimental design, only true design can establish a cause-effect relationship within a group. In a true experiment, three factors need to be satisfied:

• There is a Control Group, which won’t be subject to changes, and an Experimental Group, which will experience the changed variables.
• A variable that can be manipulated by the researcher
• Random distribution

This experimental research method commonly occurs in the physical sciences.

0 3. Quasi-Experimental Design

The word “Quasi” indicates similarity. A quasi-experimental design is similar to an experimental one, but it is not the same. The difference between the two is the assignment of a control group. In this research, an independent variable is manipulated, but the participants of a group are not randomly assigned. Quasi-research is used in field settings where random assignment is either irrelevant or not required.

Importance of Experimental Design

Experimental research is a powerful tool for understanding cause-and-effect relationships. It allows us to manipulate variables and observe the effects, which is crucial for understanding how different factors influence the outcome of a study.

But the importance of experimental research goes beyond that. It’s a critical method for many scientific and academic studies. It allows us to test theories, develop new products, and make groundbreaking discoveries.

For example, this research is essential for developing new drugs and medical treatments. Researchers can understand how a new drug works by manipulating dosage and administration variables and identifying potential side effects.

Similarly, experimental research is used in the field of psychology to test theories and understand human behavior. By manipulating variables such as stimuli, researchers can gain insights into how the brain works and identify new treatment options for mental health disorders.

It is also widely used in the field of education. It allows educators to test new teaching methods and identify what works best. By manipulating variables such as class size, teaching style, and curriculum, researchers can understand how students learn and identify new ways to improve educational outcomes.

In addition, experimental research is a powerful tool for businesses and organizations. By manipulating variables such as marketing strategies, product design, and customer service, companies can understand what works best and identify new opportunities for growth.

Advantages of Experimental Research

When talking about this research, we can think of human life. Babies do their own rudimentary experiments (such as putting objects in their mouths) to learn about the world around them, while older children and teens do experiments at school to learn more about science.

Ancient scientists used this research to prove that their hypotheses were correct. For example, Galileo Galilei and Antoine Lavoisier conducted various experiments to discover key concepts in physics and chemistry. The same is true of modern experts, who use this scientific method to see if new drugs are effective, discover treatments for diseases, and create new electronic devices (among others).

It’s vital to test new ideas or theories. Why put time, effort, and funding into something that may not work?

This research allows you to test your idea in a controlled environment before marketing. It also provides the best method to test your theory thanks to the following advantages:

• Researchers have a stronger hold over variables to obtain desired results.
• The subject or industry does not impact the effectiveness of experimental research. Any industry can implement it for research purposes.
• The results are specific.
• After analyzing the results, you can apply your findings to similar ideas or situations.
• You can identify the cause and effect of a hypothesis. Researchers can further analyze this relationship to determine more in-depth ideas.
• Experimental research makes an ideal starting point. The data you collect is a foundation for building more ideas and conducting more action research .

Whether you want to know how the public will react to a new product or if a certain food increases the chance of disease, experimental research is the best place to start. Begin your research by finding subjects using  QuestionPro Audience  and other tools today.

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• Experimental Research Designs: Types, Examples & Methods

Experimental research is the most familiar type of research design for individuals in the physical sciences and a host of other fields. This is mainly because experimental research is a classical scientific experiment, similar to those performed in high school science classes.

Imagine taking 2 samples of the same plant and exposing one of them to sunlight, while the other is kept away from sunlight. Let the plant exposed to sunlight be called sample A, while the latter is called sample B.

If after the duration of the research, we find out that sample A grows and sample B dies, even though they are both regularly wetted and given the same treatment. Therefore, we can conclude that sunlight will aid growth in all similar plants.

What is Experimental Research?

Experimental research is a scientific approach to research, where one or more independent variables are manipulated and applied to one or more dependent variables to measure their effect on the latter. The effect of the independent variables on the dependent variables is usually observed and recorded over some time, to aid researchers in drawing a reasonable conclusion regarding the relationship between these 2 variable types.

The experimental research method is widely used in physical and social sciences, psychology, and education. It is based on the comparison between two or more groups with a straightforward logic, which may, however, be difficult to execute.

Mostly related to a laboratory test procedure, experimental research designs involve collecting quantitative data and performing statistical analysis on them during research. Therefore, making it an example of quantitative research method .

What are The Types of Experimental Research Design?

The types of experimental research design are determined by the way the researcher assigns subjects to different conditions and groups. They are of 3 types, namely; pre-experimental, quasi-experimental, and true experimental research.

Pre-experimental Research Design

In pre-experimental research design, either a group or various dependent groups are observed for the effect of the application of an independent variable which is presumed to cause change. It is the simplest form of experimental research design and is treated with no control group.

Although very practical, experimental research is lacking in several areas of the true-experimental criteria. The pre-experimental research design is further divided into three types

• One-shot Case Study Research Design

In this type of experimental study, only one dependent group or variable is considered. The study is carried out after some treatment which was presumed to cause change, making it a posttest study.

• One-group Pretest-posttest Research Design: 

This research design combines both posttest and pretest study by carrying out a test on a single group before the treatment is administered and after the treatment is administered. With the former being administered at the beginning of treatment and later at the end.

• Static-group Comparison: 

In a static-group comparison study, 2 or more groups are placed under observation, where only one of the groups is subjected to some treatment while the other groups are held static. All the groups are post-tested, and the observed differences between the groups are assumed to be a result of the treatment.

Quasi-experimental Research Design

  The word “quasi” means partial, half, or pseudo. Therefore, the quasi-experimental research bearing a resemblance to the true experimental research, but not the same.  In quasi-experiments, the participants are not randomly assigned, and as such, they are used in settings where randomization is difficult or impossible.

 This is very common in educational research, where administrators are unwilling to allow the random selection of students for experimental samples.

Some examples of quasi-experimental research design include; the time series, no equivalent control group design, and the counterbalanced design.

True Experimental Research Design

The true experimental research design relies on statistical analysis to approve or disprove a hypothesis. It is the most accurate type of experimental design and may be carried out with or without a pretest on at least 2 randomly assigned dependent subjects.

The true experimental research design must contain a control group, a variable that can be manipulated by the researcher, and the distribution must be random. The classification of true experimental design include:

• The posttest-only Control Group Design: In this design, subjects are randomly selected and assigned to the 2 groups (control and experimental), and only the experimental group is treated. After close observation, both groups are post-tested, and a conclusion is drawn from the difference between these groups.
• The pretest-posttest Control Group Design: For this control group design, subjects are randomly assigned to the 2 groups, both are presented, but only the experimental group is treated. After close observation, both groups are post-tested to measure the degree of change in each group.
• Solomon four-group Design: This is the combination of the pretest-only and the pretest-posttest control groups. In this case, the randomly selected subjects are placed into 4 groups.

The first two of these groups are tested using the posttest-only method, while the other two are tested using the pretest-posttest method.

Examples of Experimental Research

Experimental research examples are different, depending on the type of experimental research design that is being considered. The most basic example of experimental research is laboratory experiments, which may differ in nature depending on the subject of research.

Administering Exams After The End of Semester

During the semester, students in a class are lectured on particular courses and an exam is administered at the end of the semester. In this case, the students are the subjects or dependent variables while the lectures are the independent variables treated on the subjects.

Only one group of carefully selected subjects are considered in this research, making it a pre-experimental research design example. We will also notice that tests are only carried out at the end of the semester, and not at the beginning.

Further making it easy for us to conclude that it is a one-shot case study research. 

Employee Skill Evaluation

Before employing a job seeker, organizations conduct tests that are used to screen out less qualified candidates from the pool of qualified applicants. This way, organizations can determine an employee’s skill set at the point of employment.

In the course of employment, organizations also carry out employee training to improve employee productivity and generally grow the organization. Further evaluation is carried out at the end of each training to test the impact of the training on employee skills, and test for improvement.

Here, the subject is the employee, while the treatment is the training conducted. This is a pretest-posttest control group experimental research example.

Evaluation of Teaching Method

Let us consider an academic institution that wants to evaluate the teaching method of 2 teachers to determine which is best. Imagine a case whereby the students assigned to each teacher is carefully selected probably due to personal request by parents or due to stubbornness and smartness.

This is a no equivalent group design example because the samples are not equal. By evaluating the effectiveness of each teacher’s teaching method this way, we may conclude after a post-test has been carried out.

However, this may be influenced by factors like the natural sweetness of a student. For example, a very smart student will grab more easily than his or her peers irrespective of the method of teaching.

What are the Characteristics of Experimental Research?  

Experimental research contains dependent, independent and extraneous variables. The dependent variables are the variables being treated or manipulated and are sometimes called the subject of the research.

The independent variables are the experimental treatment being exerted on the dependent variables. Extraneous variables, on the other hand, are other factors affecting the experiment that may also contribute to the change.

The setting is where the experiment is carried out. Many experiments are carried out in the laboratory, where control can be exerted on the extraneous variables, thereby eliminating them. 

Other experiments are carried out in a less controllable setting. The choice of setting used in research depends on the nature of the experiment being carried out.

• Multivariable

Experimental research may include multiple independent variables, e.g. time, skills, test scores, etc.

Why Use Experimental Research Design?  

Experimental research design can be majorly used in physical sciences, social sciences, education, and psychology. It is used to make predictions and draw conclusions on a subject matter. 

Some uses of experimental research design are highlighted below.

• Medicine: Experimental research is used to provide the proper treatment for diseases. In most cases, rather than directly using patients as the research subject, researchers take a sample of the bacteria from the patient’s body and are treated with the developed antibacterial

The changes observed during this period are recorded and evaluated to determine its effectiveness. This process can be carried out using different experimental research methods.

• Education: Asides from science subjects like Chemistry and Physics which involves teaching students how to perform experimental research, it can also be used in improving the standard of an academic institution. This includes testing students’ knowledge on different topics, coming up with better teaching methods, and the implementation of other programs that will aid student learning.
• Human Behavior: Social scientists are the ones who mostly use experimental research to test human behaviour. For example, consider 2 people randomly chosen to be the subject of the social interaction research where one person is placed in a room without human interaction for 1 year.

The other person is placed in a room with a few other people, enjoying human interaction. There will be a difference in their behaviour at the end of the experiment.

• UI/UX: During the product development phase, one of the major aims of the product team is to create a great user experience with the product. Therefore, before launching the final product design, potential are brought in to interact with the product.

For example, when finding it difficult to choose how to position a button or feature on the app interface, a random sample of product testers are allowed to test the 2 samples and how the button positioning influences the user interaction is recorded.

What are the Disadvantages of Experimental Research?  

• It is highly prone to human error due to its dependency on variable control which may not be properly implemented. These errors could eliminate the validity of the experiment and the research being conducted.
• Exerting control of extraneous variables may create unrealistic situations. Eliminating real-life variables will result in inaccurate conclusions. This may also result in researchers controlling the variables to suit his or her personal preferences.
• It is a time-consuming process. So much time is spent on testing dependent variables and waiting for the effect of the manipulation of dependent variables to manifest.
• It is expensive. 
• It is very risky and may have ethical complications that cannot be ignored. This is common in medical research, where failed trials may lead to a patient’s death or a deteriorating health condition.
• Experimental research results are not descriptive.
• Response bias can also be supplied by the subject of the conversation.
• Human responses in experimental research can be difficult to measure. 

What are the Data Collection Methods in Experimental Research?  

Data collection methods in experimental research are the different ways in which data can be collected for experimental research. They are used in different cases, depending on the type of research being carried out.

1. Observational Study

This type of study is carried out over a long period. It measures and observes the variables of interest without changing existing conditions.

When researching the effect of social interaction on human behavior, the subjects who are placed in 2 different environments are observed throughout the research. No matter the kind of absurd behavior that is exhibited by the subject during this period, its condition will not be changed.

This may be a very risky thing to do in medical cases because it may lead to death or worse medical conditions.

2. Simulations

This procedure uses mathematical, physical, or computer models to replicate a real-life process or situation. It is frequently used when the actual situation is too expensive, dangerous, or impractical to replicate in real life.

This method is commonly used in engineering and operational research for learning purposes and sometimes as a tool to estimate possible outcomes of real research. Some common situation software are Simulink, MATLAB, and Simul8.

Not all kinds of experimental research can be carried out using simulation as a data collection tool . It is very impractical for a lot of laboratory-based research that involves chemical processes.

A survey is a tool used to gather relevant data about the characteristics of a population and is one of the most common data collection tools. A survey consists of a group of questions prepared by the researcher, to be answered by the research subject.

Surveys can be shared with the respondents both physically and electronically. When collecting data through surveys, the kind of data collected depends on the respondent, and researchers have limited control over it.

Formplus is the best tool for collecting experimental data using survey s. It has relevant features that will aid the data collection process and can also be used in other aspects of experimental research.

Differences between Experimental and Non-Experimental Research 

1. In experimental research, the researcher can control and manipulate the environment of the research, including the predictor variable which can be changed. On the other hand, non-experimental research cannot be controlled or manipulated by the researcher at will.

This is because it takes place in a real-life setting, where extraneous variables cannot be eliminated. Therefore, it is more difficult to conclude non-experimental studies, even though they are much more flexible and allow for a greater range of study fields.

2. The relationship between cause and effect cannot be established in non-experimental research, while it can be established in experimental research. This may be because many extraneous variables also influence the changes in the research subject, making it difficult to point at a particular variable as the cause of a particular change

3. Independent variables are not introduced, withdrawn, or manipulated in non-experimental designs, but the same may not be said about experimental research.

Conclusion  

Experimental research designs are often considered to be the standard in research designs. This is partly due to the common misconception that research is equivalent to scientific experiments—a component of experimental research design.

In this research design, one or more subjects or dependent variables are randomly assigned to different treatments (i.e. independent variables manipulated by the researcher) and the results are observed to conclude. One of the uniqueness of experimental research is in its ability to control the effect of extraneous variables.

Experimental research is suitable for research whose goal is to examine cause-effect relationships, e.g. explanatory research. It can be conducted in the laboratory or field settings, depending on the aim of the research that is being carried out. 

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19+ Experimental Design Examples (Methods + Types)

Ever wondered how scientists discover new medicines, psychologists learn about behavior, or even how marketers figure out what kind of ads you like? Well, they all have something in common: they use a special plan or recipe called an "experimental design."

Imagine you're baking cookies. You can't just throw random amounts of flour, sugar, and chocolate chips into a bowl and hope for the best. You follow a recipe, right? Scientists and researchers do something similar. They follow a "recipe" called an experimental design to make sure their experiments are set up in a way that the answers they find are meaningful and reliable.

Experimental design is the roadmap researchers use to answer questions. It's a set of rules and steps that researchers follow to collect information, or "data," in a way that is fair, accurate, and makes sense.

Long ago, people didn't have detailed game plans for experiments. They often just tried things out and saw what happened. But over time, people got smarter about this. They started creating structured plans—what we now call experimental designs—to get clearer, more trustworthy answers to their questions.

In this article, we'll take you on a journey through the world of experimental designs. We'll talk about the different types, or "flavors," of experimental designs, where they're used, and even give you a peek into how they came to be.

What Is Experimental Design?

Alright, before we dive into the different types of experimental designs, let's get crystal clear on what experimental design actually is.

Imagine you're a detective trying to solve a mystery. You need clues, right? Well, in the world of research, experimental design is like the roadmap that helps you find those clues. It's like the game plan in sports or the blueprint when you're building a house. Just like you wouldn't start building without a good blueprint, researchers won't start their studies without a strong experimental design.

So, why do we need experimental design? Think about baking a cake. If you toss ingredients into a bowl without measuring, you'll end up with a mess instead of a tasty dessert.

Similarly, in research, if you don't have a solid plan, you might get confusing or incorrect results. A good experimental design helps you ask the right questions ( think critically ), decide what to measure ( come up with an idea ), and figure out how to measure it (test it). It also helps you consider things that might mess up your results, like outside influences you hadn't thought of.

For example, let's say you want to find out if listening to music helps people focus better. Your experimental design would help you decide things like: Who are you going to test? What kind of music will you use? How will you measure focus? And, importantly, how will you make sure that it's really the music affecting focus and not something else, like the time of day or whether someone had a good breakfast?

In short, experimental design is the master plan that guides researchers through the process of collecting data, so they can answer questions in the most reliable way possible. It's like the GPS for the journey of discovery!

History of Experimental Design

Around 350 BCE, people like Aristotle were trying to figure out how the world works, but they mostly just thought really hard about things. They didn't test their ideas much. So while they were super smart, their methods weren't always the best for finding out the truth.

Fast forward to the Renaissance (14th to 17th centuries), a time of big changes and lots of curiosity. People like Galileo started to experiment by actually doing tests, like rolling balls down inclined planes to study motion. Galileo's work was cool because he combined thinking with doing. He'd have an idea, test it, look at the results, and then think some more. This approach was a lot more reliable than just sitting around and thinking.

Now, let's zoom ahead to the 18th and 19th centuries. This is when people like Francis Galton, an English polymath, started to get really systematic about experimentation. Galton was obsessed with measuring things. Seriously, he even tried to measure how good-looking people were ! His work helped create the foundations for a more organized approach to experiments.

Next stop: the early 20th century. Enter Ronald A. Fisher , a brilliant British statistician. Fisher was a game-changer. He came up with ideas that are like the bread and butter of modern experimental design.

Fisher invented the concept of the " control group "—that's a group of people or things that don't get the treatment you're testing, so you can compare them to those who do. He also stressed the importance of " randomization ," which means assigning people or things to different groups by chance, like drawing names out of a hat. This makes sure the experiment is fair and the results are trustworthy.

Around the same time, American psychologists like John B. Watson and B.F. Skinner were developing " behaviorism ." They focused on studying things that they could directly observe and measure, like actions and reactions.

Skinner even built boxes—called Skinner Boxes —to test how animals like pigeons and rats learn. Their work helped shape how psychologists design experiments today. Watson performed a very controversial experiment called The Little Albert experiment that helped describe behaviour through conditioning—in other words, how people learn to behave the way they do.

In the later part of the 20th century and into our time, computers have totally shaken things up. Researchers now use super powerful software to help design their experiments and crunch the numbers.

With computers, they can simulate complex experiments before they even start, which helps them predict what might happen. This is especially helpful in fields like medicine, where getting things right can be a matter of life and death.

Also, did you know that experimental designs aren't just for scientists in labs? They're used by people in all sorts of jobs, like marketing, education, and even video game design! Yes, someone probably ran an experiment to figure out what makes a game super fun to play.

So there you have it—a quick tour through the history of experimental design, from Aristotle's deep thoughts to Fisher's groundbreaking ideas, and all the way to today's computer-powered research. These designs are the recipes that help people from all walks of life find answers to their big questions.

Key Terms in Experimental Design

Before we dig into the different types of experimental designs, let's get comfy with some key terms. Understanding these terms will make it easier for us to explore the various types of experimental designs that researchers use to answer their big questions.

Independent Variable : This is what you change or control in your experiment to see what effect it has. Think of it as the "cause" in a cause-and-effect relationship. For example, if you're studying whether different types of music help people focus, the kind of music is the independent variable.

Dependent Variable : This is what you're measuring to see the effect of your independent variable. In our music and focus experiment, how well people focus is the dependent variable—it's what "depends" on the kind of music played.

Control Group : This is a group of people who don't get the special treatment or change you're testing. They help you see what happens when the independent variable is not applied. If you're testing whether a new medicine works, the control group would take a fake pill, called a placebo , instead of the real medicine.

Experimental Group : This is the group that gets the special treatment or change you're interested in. Going back to our medicine example, this group would get the actual medicine to see if it has any effect.

Randomization : This is like shaking things up in a fair way. You randomly put people into the control or experimental group so that each group is a good mix of different kinds of people. This helps make the results more reliable.

Sample : This is the group of people you're studying. They're a "sample" of a larger group that you're interested in. For instance, if you want to know how teenagers feel about a new video game, you might study a sample of 100 teenagers.

Bias : This is anything that might tilt your experiment one way or another without you realizing it. Like if you're testing a new kind of dog food and you only test it on poodles, that could create a bias because maybe poodles just really like that food and other breeds don't.

Data : This is the information you collect during the experiment. It's like the treasure you find on your journey of discovery!

Replication : This means doing the experiment more than once to make sure your findings hold up. It's like double-checking your answers on a test.

Hypothesis : This is your educated guess about what will happen in the experiment. It's like predicting the end of a movie based on the first half.

Steps of Experimental Design

Alright, let's say you're all fired up and ready to run your own experiment. Cool! But where do you start? Well, designing an experiment is a bit like planning a road trip. There are some key steps you've got to take to make sure you reach your destination. Let's break it down:

• Ask a Question : Before you hit the road, you've got to know where you're going. Same with experiments. You start with a question you want to answer, like "Does eating breakfast really make you do better in school?"
• Do Some Homework : Before you pack your bags, you look up the best places to visit, right? In science, this means reading up on what other people have already discovered about your topic.
• Form a Hypothesis : This is your educated guess about what you think will happen. It's like saying, "I bet this route will get us there faster."
• Plan the Details : Now you decide what kind of car you're driving (your experimental design), who's coming with you (your sample), and what snacks to bring (your variables).
• Randomization : Remember, this is like shuffling a deck of cards. You want to mix up who goes into your control and experimental groups to make sure it's a fair test.
• Run the Experiment : Finally, the rubber hits the road! You carry out your plan, making sure to collect your data carefully.
• Analyze the Data : Once the trip's over, you look at your photos and decide which ones are keepers. In science, this means looking at your data to see what it tells you.
• Draw Conclusions : Based on your data, did you find an answer to your question? This is like saying, "Yep, that route was faster," or "Nope, we hit a ton of traffic."
• Share Your Findings : After a great trip, you want to tell everyone about it, right? Scientists do the same by publishing their results so others can learn from them.
• Do It Again? : Sometimes one road trip just isn't enough. In the same way, scientists often repeat their experiments to make sure their findings are solid.

So there you have it! Those are the basic steps you need to follow when you're designing an experiment. Each step helps make sure that you're setting up a fair and reliable way to find answers to your big questions.

Let's get into examples of experimental designs.

1) True Experimental Design

In the world of experiments, the True Experimental Design is like the superstar quarterback everyone talks about. Born out of the early 20th-century work of statisticians like Ronald A. Fisher, this design is all about control, precision, and reliability.

Researchers carefully pick an independent variable to manipulate (remember, that's the thing they're changing on purpose) and measure the dependent variable (the effect they're studying). Then comes the magic trick—randomization. By randomly putting participants into either the control or experimental group, scientists make sure their experiment is as fair as possible.

No sneaky biases here!

True Experimental Design Pros

The pros of True Experimental Design are like the perks of a VIP ticket at a concert: you get the best and most trustworthy results. Because everything is controlled and randomized, you can feel pretty confident that the results aren't just a fluke.

True Experimental Design Cons

However, there's a catch. Sometimes, it's really tough to set up these experiments in a real-world situation. Imagine trying to control every single detail of your day, from the food you eat to the air you breathe. Not so easy, right?

True Experimental Design Uses

The fields that get the most out of True Experimental Designs are those that need super reliable results, like medical research.

When scientists were developing COVID-19 vaccines, they used this design to run clinical trials. They had control groups that received a placebo (a harmless substance with no effect) and experimental groups that got the actual vaccine. Then they measured how many people in each group got sick. By comparing the two, they could say, "Yep, this vaccine works!"

So next time you read about a groundbreaking discovery in medicine or technology, chances are a True Experimental Design was the VIP behind the scenes, making sure everything was on point. It's been the go-to for rigorous scientific inquiry for nearly a century, and it's not stepping off the stage anytime soon.

2) Quasi-Experimental Design

So, let's talk about the Quasi-Experimental Design. Think of this one as the cool cousin of True Experimental Design. It wants to be just like its famous relative, but it's a bit more laid-back and flexible. You'll find quasi-experimental designs when it's tricky to set up a full-blown True Experimental Design with all the bells and whistles.

Quasi-experiments still play with an independent variable, just like their stricter cousins. The big difference? They don't use randomization. It's like wanting to divide a bag of jelly beans equally between your friends, but you can't quite do it perfectly.

In real life, it's often not possible or ethical to randomly assign people to different groups, especially when dealing with sensitive topics like education or social issues. And that's where quasi-experiments come in.

Quasi-Experimental Design Pros

Even though they lack full randomization, quasi-experimental designs are like the Swiss Army knives of research: versatile and practical. They're especially popular in fields like education, sociology, and public policy.

For instance, when researchers wanted to figure out if the Head Start program , aimed at giving young kids a "head start" in school, was effective, they used a quasi-experimental design. They couldn't randomly assign kids to go or not go to preschool, but they could compare kids who did with kids who didn't.

Quasi-Experimental Design Cons

Of course, quasi-experiments come with their own bag of pros and cons. On the plus side, they're easier to set up and often cheaper than true experiments. But the flip side is that they're not as rock-solid in their conclusions. Because the groups aren't randomly assigned, there's always that little voice saying, "Hey, are we missing something here?"

Quasi-Experimental Design Uses

Quasi-Experimental Design gained traction in the mid-20th century. Researchers were grappling with real-world problems that didn't fit neatly into a laboratory setting. Plus, as society became more aware of ethical considerations, the need for flexible designs increased. So, the quasi-experimental approach was like a breath of fresh air for scientists wanting to study complex issues without a laundry list of restrictions.

In short, if True Experimental Design is the superstar quarterback, Quasi-Experimental Design is the versatile player who can adapt and still make significant contributions to the game.

3) Pre-Experimental Design

Now, let's talk about the Pre-Experimental Design. Imagine it as the beginner's skateboard you get before you try out for all the cool tricks. It has wheels, it rolls, but it's not built for the professional skatepark.

Similarly, pre-experimental designs give researchers a starting point. They let you dip your toes in the water of scientific research without diving in head-first.

So, what's the deal with pre-experimental designs?

Pre-Experimental Designs are the basic, no-frills versions of experiments. Researchers still mess around with an independent variable and measure a dependent variable, but they skip over the whole randomization thing and often don't even have a control group.

It's like baking a cake but forgetting the frosting and sprinkles; you'll get some results, but they might not be as complete or reliable as you'd like.

Pre-Experimental Design Pros

Why use such a simple setup? Because sometimes, you just need to get the ball rolling. Pre-experimental designs are great for quick-and-dirty research when you're short on time or resources. They give you a rough idea of what's happening, which you can use to plan more detailed studies later.

A good example of this is early studies on the effects of screen time on kids. Researchers couldn't control every aspect of a child's life, but they could easily ask parents to track how much time their kids spent in front of screens and then look for trends in behavior or school performance.

Pre-Experimental Design Cons

But here's the catch: pre-experimental designs are like that first draft of an essay. It helps you get your ideas down, but you wouldn't want to turn it in for a grade. Because these designs lack the rigorous structure of true or quasi-experimental setups, they can't give you rock-solid conclusions. They're more like clues or signposts pointing you in a certain direction.

Pre-Experimental Design Uses

This type of design became popular in the early stages of various scientific fields. Researchers used them to scratch the surface of a topic, generate some initial data, and then decide if it's worth exploring further. In other words, pre-experimental designs were the stepping stones that led to more complex, thorough investigations.

So, while Pre-Experimental Design may not be the star player on the team, it's like the practice squad that helps everyone get better. It's the starting point that can lead to bigger and better things.

4) Factorial Design

Now, buckle up, because we're moving into the world of Factorial Design, the multi-tasker of the experimental universe.

Imagine juggling not just one, but multiple balls in the air—that's what researchers do in a factorial design.

In Factorial Design, researchers are not satisfied with just studying one independent variable. Nope, they want to study two or more at the same time to see how they interact.

It's like cooking with several spices to see how they blend together to create unique flavors.

Factorial Design became the talk of the town with the rise of computers. Why? Because this design produces a lot of data, and computers are the number crunchers that help make sense of it all. So, thanks to our silicon friends, researchers can study complicated questions like, "How do diet AND exercise together affect weight loss?" instead of looking at just one of those factors.

Factorial Design Pros

This design's main selling point is its ability to explore interactions between variables. For instance, maybe a new study drug works really well for young people but not so great for older adults. A factorial design could reveal that age is a crucial factor, something you might miss if you only studied the drug's effectiveness in general. It's like being a detective who looks for clues not just in one room but throughout the entire house.

Factorial Design Cons

However, factorial designs have their own bag of challenges. First off, they can be pretty complicated to set up and run. Imagine coordinating a four-way intersection with lots of cars coming from all directions—you've got to make sure everything runs smoothly, or you'll end up with a traffic jam. Similarly, researchers need to carefully plan how they'll measure and analyze all the different variables.

Factorial Design Uses

Factorial designs are widely used in psychology to untangle the web of factors that influence human behavior. They're also popular in fields like marketing, where companies want to understand how different aspects like price, packaging, and advertising influence a product's success.

And speaking of success, the factorial design has been a hit since statisticians like Ronald A. Fisher (yep, him again!) expanded on it in the early-to-mid 20th century. It offered a more nuanced way of understanding the world, proving that sometimes, to get the full picture, you've got to juggle more than one ball at a time.

So, if True Experimental Design is the quarterback and Quasi-Experimental Design is the versatile player, Factorial Design is the strategist who sees the entire game board and makes moves accordingly.

5) Longitudinal Design

Alright, let's take a step into the world of Longitudinal Design. Picture it as the grand storyteller, the kind who doesn't just tell you about a single event but spins an epic tale that stretches over years or even decades. This design isn't about quick snapshots; it's about capturing the whole movie of someone's life or a long-running process.

You know how you might take a photo every year on your birthday to see how you've changed? Longitudinal Design is kind of like that, but for scientific research.

With Longitudinal Design, instead of measuring something just once, researchers come back again and again, sometimes over many years, to see how things are going. This helps them understand not just what's happening, but why it's happening and how it changes over time.

This design really started to shine in the latter half of the 20th century, when researchers began to realize that some questions can't be answered in a hurry. Think about studies that look at how kids grow up, or research on how a certain medicine affects you over a long period. These aren't things you can rush.

The famous Framingham Heart Study , started in 1948, is a prime example. It's been studying heart health in a small town in Massachusetts for decades, and the findings have shaped what we know about heart disease.

Longitudinal Design Pros

So, what's to love about Longitudinal Design? First off, it's the go-to for studying change over time, whether that's how people age or how a forest recovers from a fire.

Longitudinal Design Cons

But it's not all sunshine and rainbows. Longitudinal studies take a lot of patience and resources. Plus, keeping track of participants over many years can be like herding cats—difficult and full of surprises.

Longitudinal Design Uses

Despite these challenges, longitudinal studies have been key in fields like psychology, sociology, and medicine. They provide the kind of deep, long-term insights that other designs just can't match.

So, if the True Experimental Design is the superstar quarterback, and the Quasi-Experimental Design is the flexible athlete, then the Factorial Design is the strategist, and the Longitudinal Design is the wise elder who has seen it all and has stories to tell.

6) Cross-Sectional Design

Now, let's flip the script and talk about Cross-Sectional Design, the polar opposite of the Longitudinal Design. If Longitudinal is the grand storyteller, think of Cross-Sectional as the snapshot photographer. It captures a single moment in time, like a selfie that you take to remember a fun day. Researchers using this design collect all their data at one point, providing a kind of "snapshot" of whatever they're studying.

In a Cross-Sectional Design, researchers look at multiple groups all at the same time to see how they're different or similar.

This design rose to popularity in the mid-20th century, mainly because it's so quick and efficient. Imagine wanting to know how people of different ages feel about a new video game. Instead of waiting for years to see how opinions change, you could just ask people of all ages what they think right now. That's Cross-Sectional Design for you—fast and straightforward.

You'll find this type of research everywhere from marketing studies to healthcare. For instance, you might have heard about surveys asking people what they think about a new product or political issue. Those are usually cross-sectional studies, aimed at getting a quick read on public opinion.

Cross-Sectional Design Pros

So, what's the big deal with Cross-Sectional Design? Well, it's the go-to when you need answers fast and don't have the time or resources for a more complicated setup.

Cross-Sectional Design Cons

Remember, speed comes with trade-offs. While you get your results quickly, those results are stuck in time. They can't tell you how things change or why they're changing, just what's happening right now.

Cross-Sectional Design Uses

Also, because they're so quick and simple, cross-sectional studies often serve as the first step in research. They give scientists an idea of what's going on so they can decide if it's worth digging deeper. In that way, they're a bit like a movie trailer, giving you a taste of the action to see if you're interested in seeing the whole film.

So, in our lineup of experimental designs, if True Experimental Design is the superstar quarterback and Longitudinal Design is the wise elder, then Cross-Sectional Design is like the speedy running back—fast, agile, but not designed for long, drawn-out plays.

7) Correlational Design

Next on our roster is the Correlational Design, the keen observer of the experimental world. Imagine this design as the person at a party who loves people-watching. They don't interfere or get involved; they just observe and take mental notes about what's going on.

In a correlational study, researchers don't change or control anything; they simply observe and measure how two variables relate to each other.

The correlational design has roots in the early days of psychology and sociology. Pioneers like Sir Francis Galton used it to study how qualities like intelligence or height could be related within families.

This design is all about asking, "Hey, when this thing happens, does that other thing usually happen too?" For example, researchers might study whether students who have more study time get better grades or whether people who exercise more have lower stress levels.

One of the most famous correlational studies you might have heard of is the link between smoking and lung cancer. Back in the mid-20th century, researchers started noticing that people who smoked a lot also seemed to get lung cancer more often. They couldn't say smoking caused cancer—that would require a true experiment—but the strong correlation was a red flag that led to more research and eventually, health warnings.

Correlational Design Pros

This design is great at proving that two (or more) things can be related. Correlational designs can help prove that more detailed research is needed on a topic. They can help us see patterns or possible causes for things that we otherwise might not have realized.

Correlational Design Cons

But here's where you need to be careful: correlational designs can be tricky. Just because two things are related doesn't mean one causes the other. That's like saying, "Every time I wear my lucky socks, my team wins." Well, it's a fun thought, but those socks aren't really controlling the game.

Correlational Design Uses

Despite this limitation, correlational designs are popular in psychology, economics, and epidemiology, to name a few fields. They're often the first step in exploring a possible relationship between variables. Once a strong correlation is found, researchers may decide to conduct more rigorous experimental studies to examine cause and effect.

So, if the True Experimental Design is the superstar quarterback and the Longitudinal Design is the wise elder, the Factorial Design is the strategist, and the Cross-Sectional Design is the speedster, then the Correlational Design is the clever scout, identifying interesting patterns but leaving the heavy lifting of proving cause and effect to the other types of designs.

8) Meta-Analysis

Last but not least, let's talk about Meta-Analysis, the librarian of experimental designs.

If other designs are all about creating new research, Meta-Analysis is about gathering up everyone else's research, sorting it, and figuring out what it all means when you put it together.

Imagine a jigsaw puzzle where each piece is a different study. Meta-Analysis is the process of fitting all those pieces together to see the big picture.

The concept of Meta-Analysis started to take shape in the late 20th century, when computers became powerful enough to handle massive amounts of data. It was like someone handed researchers a super-powered magnifying glass, letting them examine multiple studies at the same time to find common trends or results.

You might have heard of the Cochrane Reviews in healthcare . These are big collections of meta-analyses that help doctors and policymakers figure out what treatments work best based on all the research that's been done.

For example, if ten different studies show that a certain medicine helps lower blood pressure, a meta-analysis would pull all that information together to give a more accurate answer.

Meta-Analysis Pros

The beauty of Meta-Analysis is that it can provide really strong evidence. Instead of relying on one study, you're looking at the whole landscape of research on a topic.

Meta-Analysis Cons

However, it does have some downsides. For one, Meta-Analysis is only as good as the studies it includes. If those studies are flawed, the meta-analysis will be too. It's like baking a cake: if you use bad ingredients, it doesn't matter how good your recipe is—the cake won't turn out well.

Meta-Analysis Uses

Despite these challenges, meta-analyses are highly respected and widely used in many fields like medicine, psychology, and education. They help us make sense of a world that's bursting with information by showing us the big picture drawn from many smaller snapshots.

So, in our all-star lineup, if True Experimental Design is the quarterback and Longitudinal Design is the wise elder, the Factorial Design is the strategist, the Cross-Sectional Design is the speedster, and the Correlational Design is the scout, then the Meta-Analysis is like the coach, using insights from everyone else's plays to come up with the best game plan.

9) Non-Experimental Design

Now, let's talk about a player who's a bit of an outsider on this team of experimental designs—the Non-Experimental Design. Think of this design as the commentator or the journalist who covers the game but doesn't actually play.

In a Non-Experimental Design, researchers are like reporters gathering facts, but they don't interfere or change anything. They're simply there to describe and analyze.

Non-Experimental Design Pros

So, what's the deal with Non-Experimental Design? Its strength is in description and exploration. It's really good for studying things as they are in the real world, without changing any conditions.

Non-Experimental Design Cons

Because a non-experimental design doesn't manipulate variables, it can't prove cause and effect. It's like a weather reporter: they can tell you it's raining, but they can't tell you why it's raining.

The downside? Since researchers aren't controlling variables, it's hard to rule out other explanations for what they observe. It's like hearing one side of a story—you get an idea of what happened, but it might not be the complete picture.

Non-Experimental Design Uses

Non-Experimental Design has always been a part of research, especially in fields like anthropology, sociology, and some areas of psychology.

For instance, if you've ever heard of studies that describe how people behave in different cultures or what teens like to do in their free time, that's often Non-Experimental Design at work. These studies aim to capture the essence of a situation, like painting a portrait instead of taking a snapshot.

One well-known example you might have heard about is the Kinsey Reports from the 1940s and 1950s, which described sexual behavior in men and women. Researchers interviewed thousands of people but didn't manipulate any variables like you would in a true experiment. They simply collected data to create a comprehensive picture of the subject matter.

So, in our metaphorical team of research designs, if True Experimental Design is the quarterback and Longitudinal Design is the wise elder, Factorial Design is the strategist, Cross-Sectional Design is the speedster, Correlational Design is the scout, and Meta-Analysis is the coach, then Non-Experimental Design is the sports journalist—always present, capturing the game, but not part of the action itself.

10) Repeated Measures Design

Time to meet the Repeated Measures Design, the time traveler of our research team. If this design were a player in a sports game, it would be the one who keeps revisiting past plays to figure out how to improve the next one.

Repeated Measures Design is all about studying the same people or subjects multiple times to see how they change or react under different conditions.

The idea behind Repeated Measures Design isn't new; it's been around since the early days of psychology and medicine. You could say it's a cousin to the Longitudinal Design, but instead of looking at how things naturally change over time, it focuses on how the same group reacts to different things.

Imagine a study looking at how a new energy drink affects people's running speed. Instead of comparing one group that drank the energy drink to another group that didn't, a Repeated Measures Design would have the same group of people run multiple times—once with the energy drink, and once without. This way, you're really zeroing in on the effect of that energy drink, making the results more reliable.

Repeated Measures Design Pros

The strong point of Repeated Measures Design is that it's super focused. Because it uses the same subjects, you don't have to worry about differences between groups messing up your results.

Repeated Measures Design Cons

But the downside? Well, people can get tired or bored if they're tested too many times, which might affect how they respond.

Repeated Measures Design Uses

A famous example of this design is the "Little Albert" experiment, conducted by John B. Watson and Rosalie Rayner in 1920. In this study, a young boy was exposed to a white rat and other stimuli several times to see how his emotional responses changed. Though the ethical standards of this experiment are often criticized today, it was groundbreaking in understanding conditioned emotional responses.

In our metaphorical lineup of research designs, if True Experimental Design is the quarterback and Longitudinal Design is the wise elder, Factorial Design is the strategist, Cross-Sectional Design is the speedster, Correlational Design is the scout, Meta-Analysis is the coach, and Non-Experimental Design is the journalist, then Repeated Measures Design is the time traveler—always looping back to fine-tune the game plan.

11) Crossover Design

Next up is Crossover Design, the switch-hitter of the research world. If you're familiar with baseball, you'll know a switch-hitter is someone who can bat both right-handed and left-handed.

In a similar way, Crossover Design allows subjects to experience multiple conditions, flipping them around so that everyone gets a turn in each role.

This design is like the utility player on our team—versatile, flexible, and really good at adapting.

The Crossover Design has its roots in medical research and has been popular since the mid-20th century. It's often used in clinical trials to test the effectiveness of different treatments.

Crossover Design Pros

The neat thing about this design is that it allows each participant to serve as their own control group. Imagine you're testing two new kinds of headache medicine. Instead of giving one type to one group and another type to a different group, you'd give both kinds to the same people but at different times.

Crossover Design Cons

What's the big deal with Crossover Design? Its major strength is in reducing the "noise" that comes from individual differences. Since each person experiences all conditions, it's easier to see real effects. However, there's a catch. This design assumes that there's no lasting effect from the first condition when you switch to the second one. That might not always be true. If the first treatment has a long-lasting effect, it could mess up the results when you switch to the second treatment.

Crossover Design Uses

A well-known example of Crossover Design is in studies that look at the effects of different types of diets—like low-carb vs. low-fat diets. Researchers might have participants follow a low-carb diet for a few weeks, then switch them to a low-fat diet. By doing this, they can more accurately measure how each diet affects the same group of people.

In our team of experimental designs, if True Experimental Design is the quarterback and Longitudinal Design is the wise elder, Factorial Design is the strategist, Cross-Sectional Design is the speedster, Correlational Design is the scout, Meta-Analysis is the coach, Non-Experimental Design is the journalist, and Repeated Measures Design is the time traveler, then Crossover Design is the versatile utility player—always ready to adapt and play multiple roles to get the most accurate results.

12) Cluster Randomized Design

Meet the Cluster Randomized Design, the team captain of group-focused research. In our imaginary lineup of experimental designs, if other designs focus on individual players, then Cluster Randomized Design is looking at how the entire team functions.

This approach is especially common in educational and community-based research, and it's been gaining traction since the late 20th century.

Here's how Cluster Randomized Design works: Instead of assigning individual people to different conditions, researchers assign entire groups, or "clusters." These could be schools, neighborhoods, or even entire towns. This helps you see how the new method works in a real-world setting.

Imagine you want to see if a new anti-bullying program really works. Instead of selecting individual students, you'd introduce the program to a whole school or maybe even several schools, and then compare the results to schools without the program.

Cluster Randomized Design Pros

Why use Cluster Randomized Design? Well, sometimes it's just not practical to assign conditions at the individual level. For example, you can't really have half a school following a new reading program while the other half sticks with the old one; that would be way too confusing! Cluster Randomization helps get around this problem by treating each "cluster" as its own mini-experiment.

Cluster Randomized Design Cons

There's a downside, too. Because entire groups are assigned to each condition, there's a risk that the groups might be different in some important way that the researchers didn't account for. That's like having one sports team that's full of veterans playing against a team of rookies; the match wouldn't be fair.

Cluster Randomized Design Uses

A famous example is the research conducted to test the effectiveness of different public health interventions, like vaccination programs. Researchers might roll out a vaccination program in one community but not in another, then compare the rates of disease in both.

In our metaphorical research team, if True Experimental Design is the quarterback, Longitudinal Design is the wise elder, Factorial Design is the strategist, Cross-Sectional Design is the speedster, Correlational Design is the scout, Meta-Analysis is the coach, Non-Experimental Design is the journalist, Repeated Measures Design is the time traveler, and Crossover Design is the utility player, then Cluster Randomized Design is the team captain—always looking out for the group as a whole.

13) Mixed-Methods Design

Say hello to Mixed-Methods Design, the all-rounder or the "Renaissance player" of our research team.

Mixed-Methods Design uses a blend of both qualitative and quantitative methods to get a more complete picture, just like a Renaissance person who's good at lots of different things. It's like being good at both offense and defense in a sport; you've got all your bases covered!

Mixed-Methods Design is a fairly new kid on the block, becoming more popular in the late 20th and early 21st centuries as researchers began to see the value in using multiple approaches to tackle complex questions. It's the Swiss Army knife in our research toolkit, combining the best parts of other designs to be more versatile.

Here's how it could work: Imagine you're studying the effects of a new educational app on students' math skills. You might use quantitative methods like tests and grades to measure how much the students improve—that's the 'numbers part.'

But you also want to know how the students feel about math now, or why they think they got better or worse. For that, you could conduct interviews or have students fill out journals—that's the 'story part.'

Mixed-Methods Design Pros

So, what's the scoop on Mixed-Methods Design? The strength is its versatility and depth; you're not just getting numbers or stories, you're getting both, which gives a fuller picture.

Mixed-Methods Design Cons

But, it's also more challenging. Imagine trying to play two sports at the same time! You have to be skilled in different research methods and know how to combine them effectively.

Mixed-Methods Design Uses

A high-profile example of Mixed-Methods Design is research on climate change. Scientists use numbers and data to show temperature changes (quantitative), but they also interview people to understand how these changes are affecting communities (qualitative).

In our team of experimental designs, if True Experimental Design is the quarterback, Longitudinal Design is the wise elder, Factorial Design is the strategist, Cross-Sectional Design is the speedster, Correlational Design is the scout, Meta-Analysis is the coach, Non-Experimental Design is the journalist, Repeated Measures Design is the time traveler, Crossover Design is the utility player, and Cluster Randomized Design is the team captain, then Mixed-Methods Design is the Renaissance player—skilled in multiple areas and able to bring them all together for a winning strategy.

14) Multivariate Design

Now, let's turn our attention to Multivariate Design, the multitasker of the research world.

If our lineup of research designs were like players on a basketball court, Multivariate Design would be the player dribbling, passing, and shooting all at once. This design doesn't just look at one or two things; it looks at several variables simultaneously to see how they interact and affect each other.

Multivariate Design is like baking a cake with many ingredients. Instead of just looking at how flour affects the cake, you also consider sugar, eggs, and milk all at once. This way, you understand how everything works together to make the cake taste good or bad.

Multivariate Design has been a go-to method in psychology, economics, and social sciences since the latter half of the 20th century. With the advent of computers and advanced statistical software, analyzing multiple variables at once became a lot easier, and Multivariate Design soared in popularity.

Multivariate Design Pros

So, what's the benefit of using Multivariate Design? Its power lies in its complexity. By studying multiple variables at the same time, you can get a really rich, detailed understanding of what's going on.

Multivariate Design Cons

But that complexity can also be a drawback. With so many variables, it can be tough to tell which ones are really making a difference and which ones are just along for the ride.

Multivariate Design Uses

Imagine you're a coach trying to figure out the best strategy to win games. You wouldn't just look at how many points your star player scores; you'd also consider assists, rebounds, turnovers, and maybe even how loud the crowd is. A Multivariate Design would help you understand how all these factors work together to determine whether you win or lose.

A well-known example of Multivariate Design is in market research. Companies often use this approach to figure out how different factors—like price, packaging, and advertising—affect sales. By studying multiple variables at once, they can find the best combination to boost profits.

In our metaphorical research team, if True Experimental Design is the quarterback, Longitudinal Design is the wise elder, Factorial Design is the strategist, Cross-Sectional Design is the speedster, Correlational Design is the scout, Meta-Analysis is the coach, Non-Experimental Design is the journalist, Repeated Measures Design is the time traveler, Crossover Design is the utility player, Cluster Randomized Design is the team captain, and Mixed-Methods Design is the Renaissance player, then Multivariate Design is the multitasker—juggling many variables at once to get a fuller picture of what's happening.

15) Pretest-Posttest Design

Let's introduce Pretest-Posttest Design, the "Before and After" superstar of our research team. You've probably seen those before-and-after pictures in ads for weight loss programs or home renovations, right?

Well, this design is like that, but for science! Pretest-Posttest Design checks out what things are like before the experiment starts and then compares that to what things are like after the experiment ends.

This design is one of the classics, a staple in research for decades across various fields like psychology, education, and healthcare. It's so simple and straightforward that it has stayed popular for a long time.

In Pretest-Posttest Design, you measure your subject's behavior or condition before you introduce any changes—that's your "before" or "pretest." Then you do your experiment, and after it's done, you measure the same thing again—that's your "after" or "posttest."

Pretest-Posttest Design Pros

What makes Pretest-Posttest Design special? It's pretty easy to understand and doesn't require fancy statistics.

Pretest-Posttest Design Cons

But there are some pitfalls. For example, what if the kids in our math example get better at multiplication just because they're older or because they've taken the test before? That would make it hard to tell if the program is really effective or not.

Pretest-Posttest Design Uses

Let's say you're a teacher and you want to know if a new math program helps kids get better at multiplication. First, you'd give all the kids a multiplication test—that's your pretest. Then you'd teach them using the new math program. At the end, you'd give them the same test again—that's your posttest. If the kids do better on the second test, you might conclude that the program works.

One famous use of Pretest-Posttest Design is in evaluating the effectiveness of driver's education courses. Researchers will measure people's driving skills before and after the course to see if they've improved.

16) Solomon Four-Group Design

Next up is the Solomon Four-Group Design, the "chess master" of our research team. This design is all about strategy and careful planning. Named after Richard L. Solomon who introduced it in the 1940s, this method tries to correct some of the weaknesses in simpler designs, like the Pretest-Posttest Design.

Here's how it rolls: The Solomon Four-Group Design uses four different groups to test a hypothesis. Two groups get a pretest, then one of them receives the treatment or intervention, and both get a posttest. The other two groups skip the pretest, and only one of them receives the treatment before they both get a posttest.

Sound complicated? It's like playing 4D chess; you're thinking several moves ahead!

Solomon Four-Group Design Pros

What's the pro and con of the Solomon Four-Group Design? On the plus side, it provides really robust results because it accounts for so many variables.

Solomon Four-Group Design Cons

The downside? It's a lot of work and requires a lot of participants, making it more time-consuming and costly.

Solomon Four-Group Design Uses

Let's say you want to figure out if a new way of teaching history helps students remember facts better. Two classes take a history quiz (pretest), then one class uses the new teaching method while the other sticks with the old way. Both classes take another quiz afterward (posttest).

Meanwhile, two more classes skip the initial quiz, and then one uses the new method before both take the final quiz. Comparing all four groups will give you a much clearer picture of whether the new teaching method works and whether the pretest itself affects the outcome.

The Solomon Four-Group Design is less commonly used than simpler designs but is highly respected for its ability to control for more variables. It's a favorite in educational and psychological research where you really want to dig deep and figure out what's actually causing changes.

17) Adaptive Designs

Now, let's talk about Adaptive Designs, the chameleons of the experimental world.

Imagine you're a detective, and halfway through solving a case, you find a clue that changes everything. You wouldn't just stick to your old plan; you'd adapt and change your approach, right? That's exactly what Adaptive Designs allow researchers to do.

In an Adaptive Design, researchers can make changes to the study as it's happening, based on early results. In a traditional study, once you set your plan, you stick to it from start to finish.

Adaptive Design Pros

This method is particularly useful in fast-paced or high-stakes situations, like developing a new vaccine in the middle of a pandemic. The ability to adapt can save both time and resources, and more importantly, it can save lives by getting effective treatments out faster.

Adaptive Design Cons

But Adaptive Designs aren't without their drawbacks. They can be very complex to plan and carry out, and there's always a risk that the changes made during the study could introduce bias or errors.

Adaptive Design Uses

Adaptive Designs are most often seen in clinical trials, particularly in the medical and pharmaceutical fields.

For instance, if a new drug is showing really promising results, the study might be adjusted to give more participants the new treatment instead of a placebo. Or if one dose level is showing bad side effects, it might be dropped from the study.

The best part is, these changes are pre-planned. Researchers lay out in advance what changes might be made and under what conditions, which helps keep everything scientific and above board.

In terms of applications, besides their heavy usage in medical and pharmaceutical research, Adaptive Designs are also becoming increasingly popular in software testing and market research. In these fields, being able to quickly adjust to early results can give companies a significant advantage.

Adaptive Designs are like the agile startups of the research world—quick to pivot, keen to learn from ongoing results, and focused on rapid, efficient progress. However, they require a great deal of expertise and careful planning to ensure that the adaptability doesn't compromise the integrity of the research.

18) Bayesian Designs

Next, let's dive into Bayesian Designs, the data detectives of the research universe. Named after Thomas Bayes, an 18th-century statistician and minister, this design doesn't just look at what's happening now; it also takes into account what's happened before.

Imagine if you were a detective who not only looked at the evidence in front of you but also used your past cases to make better guesses about your current one. That's the essence of Bayesian Designs.

Bayesian Designs are like detective work in science. As you gather more clues (or data), you update your best guess on what's really happening. This way, your experiment gets smarter as it goes along.

In the world of research, Bayesian Designs are most notably used in areas where you have some prior knowledge that can inform your current study. For example, if earlier research shows that a certain type of medicine usually works well for a specific illness, a Bayesian Design would include that information when studying a new group of patients with the same illness.

Bayesian Design Pros

One of the major advantages of Bayesian Designs is their efficiency. Because they use existing data to inform the current experiment, often fewer resources are needed to reach a reliable conclusion.

Bayesian Design Cons

However, they can be quite complicated to set up and require a deep understanding of both statistics and the subject matter at hand.

Bayesian Design Uses

Bayesian Designs are highly valued in medical research, finance, environmental science, and even in Internet search algorithms. Their ability to continually update and refine hypotheses based on new evidence makes them particularly useful in fields where data is constantly evolving and where quick, informed decisions are crucial.

Here's a real-world example: In the development of personalized medicine, where treatments are tailored to individual patients, Bayesian Designs are invaluable. If a treatment has been effective for patients with similar genetics or symptoms in the past, a Bayesian approach can use that data to predict how well it might work for a new patient.

This type of design is also increasingly popular in machine learning and artificial intelligence. In these fields, Bayesian Designs help algorithms "learn" from past data to make better predictions or decisions in new situations. It's like teaching a computer to be a detective that gets better and better at solving puzzles the more puzzles it sees.

19) Covariate Adaptive Randomization

Now let's turn our attention to Covariate Adaptive Randomization, which you can think of as the "matchmaker" of experimental designs.

Picture a soccer coach trying to create the most balanced teams for a friendly match. They wouldn't just randomly assign players; they'd take into account each player's skills, experience, and other traits.

Covariate Adaptive Randomization is all about creating the most evenly matched groups possible for an experiment.

In traditional randomization, participants are allocated to different groups purely by chance. This is a pretty fair way to do things, but it can sometimes lead to unbalanced groups.

Imagine if all the professional-level players ended up on one soccer team and all the beginners on another; that wouldn't be a very informative match! Covariate Adaptive Randomization fixes this by using important traits or characteristics (called "covariates") to guide the randomization process.

Covariate Adaptive Randomization Pros

The benefits of this design are pretty clear: it aims for balance and fairness, making the final results more trustworthy.

Covariate Adaptive Randomization Cons

But it's not perfect. It can be complex to implement and requires a deep understanding of which characteristics are most important to balance.

Covariate Adaptive Randomization Uses

This design is particularly useful in medical trials. Let's say researchers are testing a new medication for high blood pressure. Participants might have different ages, weights, or pre-existing conditions that could affect the results.

Covariate Adaptive Randomization would make sure that each treatment group has a similar mix of these characteristics, making the results more reliable and easier to interpret.

In practical terms, this design is often seen in clinical trials for new drugs or therapies, but its principles are also applicable in fields like psychology, education, and social sciences.

For instance, in educational research, it might be used to ensure that classrooms being compared have similar distributions of students in terms of academic ability, socioeconomic status, and other factors.

Covariate Adaptive Randomization is like the wise elder of the group, ensuring that everyone has an equal opportunity to show their true capabilities, thereby making the collective results as reliable as possible.

20) Stepped Wedge Design

Let's now focus on the Stepped Wedge Design, a thoughtful and cautious member of the experimental design family.

Imagine you're trying out a new gardening technique, but you're not sure how well it will work. You decide to apply it to one section of your garden first, watch how it performs, and then gradually extend the technique to other sections. This way, you get to see its effects over time and across different conditions. That's basically how Stepped Wedge Design works.

In a Stepped Wedge Design, all participants or clusters start off in the control group, and then, at different times, they 'step' over to the intervention or treatment group. This creates a wedge-like pattern over time where more and more participants receive the treatment as the study progresses. It's like rolling out a new policy in phases, monitoring its impact at each stage before extending it to more people.

Stepped Wedge Design Pros

The Stepped Wedge Design offers several advantages. Firstly, it allows for the study of interventions that are expected to do more good than harm, which makes it ethically appealing.

Secondly, it's useful when resources are limited and it's not feasible to roll out a new treatment to everyone at once. Lastly, because everyone eventually receives the treatment, it can be easier to get buy-in from participants or organizations involved in the study.

Stepped Wedge Design Cons

However, this design can be complex to analyze because it has to account for both the time factor and the changing conditions in each 'step' of the wedge. And like any study where participants know they're receiving an intervention, there's the potential for the results to be influenced by the placebo effect or other biases.

Stepped Wedge Design Uses

This design is particularly useful in health and social care research. For instance, if a hospital wants to implement a new hygiene protocol, it might start in one department, assess its impact, and then roll it out to other departments over time. This allows the hospital to adjust and refine the new protocol based on real-world data before it's fully implemented.

In terms of applications, Stepped Wedge Designs are commonly used in public health initiatives, organizational changes in healthcare settings, and social policy trials. They are particularly useful in situations where an intervention is being rolled out gradually and it's important to understand its impacts at each stage.

21) Sequential Design

Next up is Sequential Design, the dynamic and flexible member of our experimental design family.

Imagine you're playing a video game where you can choose different paths. If you take one path and find a treasure chest, you might decide to continue in that direction. If you hit a dead end, you might backtrack and try a different route. Sequential Design operates in a similar fashion, allowing researchers to make decisions at different stages based on what they've learned so far.

In a Sequential Design, the experiment is broken down into smaller parts, or "sequences." After each sequence, researchers pause to look at the data they've collected. Based on those findings, they then decide whether to stop the experiment because they've got enough information, or to continue and perhaps even modify the next sequence.

Sequential Design Pros

This allows for a more efficient use of resources, as you're only continuing with the experiment if the data suggests it's worth doing so.

One of the great things about Sequential Design is its efficiency. Because you're making data-driven decisions along the way, you can often reach conclusions more quickly and with fewer resources.

Sequential Design Cons

However, it requires careful planning and expertise to ensure that these "stop or go" decisions are made correctly and without bias.

Sequential Design Uses

In terms of its applications, besides healthcare and medicine, Sequential Design is also popular in quality control in manufacturing, environmental monitoring, and financial modeling. In these areas, being able to make quick decisions based on incoming data can be a big advantage.

This design is often used in clinical trials involving new medications or treatments. For example, if early results show that a new drug has significant side effects, the trial can be stopped before more people are exposed to it.

On the flip side, if the drug is showing promising results, the trial might be expanded to include more participants or to extend the testing period.

Think of Sequential Design as the nimble athlete of experimental designs, capable of quick pivots and adjustments to reach the finish line in the most effective way possible. But just like an athlete needs a good coach, this design requires expert oversight to make sure it stays on the right track.

22) Field Experiments

Last but certainly not least, let's explore Field Experiments—the adventurers of the experimental design world.

Picture a scientist leaving the controlled environment of a lab to test a theory in the real world, like a biologist studying animals in their natural habitat or a social scientist observing people in a real community. These are Field Experiments, and they're all about getting out there and gathering data in real-world settings.

Field Experiments embrace the messiness of the real world, unlike laboratory experiments, where everything is controlled down to the smallest detail. This makes them both exciting and challenging.

Field Experiment Pros

On one hand, the results often give us a better understanding of how things work outside the lab.

While Field Experiments offer real-world relevance, they come with challenges like controlling for outside factors and the ethical considerations of intervening in people's lives without their knowledge.

Field Experiment Cons

On the other hand, the lack of control can make it harder to tell exactly what's causing what. Yet, despite these challenges, they remain a valuable tool for researchers who want to understand how theories play out in the real world.

Field Experiment Uses

Let's say a school wants to improve student performance. In a Field Experiment, they might change the school's daily schedule for one semester and keep track of how students perform compared to another school where the schedule remained the same.

Because the study is happening in a real school with real students, the results could be very useful for understanding how the change might work in other schools. But since it's the real world, lots of other factors—like changes in teachers or even the weather—could affect the results.

Field Experiments are widely used in economics, psychology, education, and public policy. For example, you might have heard of the famous "Broken Windows" experiment in the 1980s that looked at how small signs of disorder, like broken windows or graffiti, could encourage more serious crime in neighborhoods. This experiment had a big impact on how cities think about crime prevention.

From the foundational concepts of control groups and independent variables to the sophisticated layouts like Covariate Adaptive Randomization and Sequential Design, it's clear that the realm of experimental design is as varied as it is fascinating.

We've seen that each design has its own special talents, ideal for specific situations. Some designs, like the Classic Controlled Experiment, are like reliable old friends you can always count on.

Others, like Sequential Design, are flexible and adaptable, making quick changes based on what they learn. And let's not forget the adventurous Field Experiments, which take us out of the lab and into the real world to discover things we might not see otherwise.

Choosing the right experimental design is like picking the right tool for the job. The method you choose can make a big difference in how reliable your results are and how much people will trust what you've discovered. And as we've learned, there's a design to suit just about every question, every problem, and every curiosity.

So the next time you read about a new discovery in medicine, psychology, or any other field, you'll have a better understanding of the thought and planning that went into figuring things out. Experimental design is more than just a set of rules; it's a structured way to explore the unknown and answer questions that can change the world.

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Home » Experimental Design – Types, Methods, Guide

Experimental Design – Types, Methods, Guide

Table of Contents

Experimental Design

Experimental design is a process of planning and conducting scientific experiments to investigate a hypothesis or research question. It involves carefully designing an experiment that can test the hypothesis, and controlling for other variables that may influence the results.

Experimental design typically includes identifying the variables that will be manipulated or measured, defining the sample or population to be studied, selecting an appropriate method of sampling, choosing a method for data collection and analysis, and determining the appropriate statistical tests to use.

Types of Experimental Design

Here are the different types of experimental design:

Completely Randomized Design

In this design, participants are randomly assigned to one of two or more groups, and each group is exposed to a different treatment or condition.

Randomized Block Design

This design involves dividing participants into blocks based on a specific characteristic, such as age or gender, and then randomly assigning participants within each block to one of two or more treatment groups.

Factorial Design

In a factorial design, participants are randomly assigned to one of several groups, each of which receives a different combination of two or more independent variables.

Repeated Measures Design

In this design, each participant is exposed to all of the different treatments or conditions, either in a random order or in a predetermined order.

Crossover Design

This design involves randomly assigning participants to one of two or more treatment groups, with each group receiving one treatment during the first phase of the study and then switching to a different treatment during the second phase.

Split-plot Design

In this design, the researcher manipulates one or more variables at different levels and uses a randomized block design to control for other variables.

Nested Design

This design involves grouping participants within larger units, such as schools or households, and then randomly assigning these units to different treatment groups.

Laboratory Experiment

Laboratory experiments are conducted under controlled conditions, which allows for greater precision and accuracy. However, because laboratory conditions are not always representative of real-world conditions, the results of these experiments may not be generalizable to the population at large.

Field Experiment

Field experiments are conducted in naturalistic settings and allow for more realistic observations. However, because field experiments are not as controlled as laboratory experiments, they may be subject to more sources of error.

Experimental Design Methods

Experimental design methods refer to the techniques and procedures used to design and conduct experiments in scientific research. Here are some common experimental design methods:

Randomization

This involves randomly assigning participants to different groups or treatments to ensure that any observed differences between groups are due to the treatment and not to other factors.

Control Group

The use of a control group is an important experimental design method that involves having a group of participants that do not receive the treatment or intervention being studied. The control group is used as a baseline to compare the effects of the treatment group.

Blinding involves keeping participants, researchers, or both unaware of which treatment group participants are in, in order to reduce the risk of bias in the results.

Counterbalancing

This involves systematically varying the order in which participants receive treatments or interventions in order to control for order effects.

Replication

Replication involves conducting the same experiment with different samples or under different conditions to increase the reliability and validity of the results.

This experimental design method involves manipulating multiple independent variables simultaneously to investigate their combined effects on the dependent variable.

This involves dividing participants into subgroups or blocks based on specific characteristics, such as age or gender, in order to reduce the risk of confounding variables.

Data Collection Method

Experimental design data collection methods are techniques and procedures used to collect data in experimental research. Here are some common experimental design data collection methods:

Direct Observation

This method involves observing and recording the behavior or phenomenon of interest in real time. It may involve the use of structured or unstructured observation, and may be conducted in a laboratory or naturalistic setting.

Self-report Measures

Self-report measures involve asking participants to report their thoughts, feelings, or behaviors using questionnaires, surveys, or interviews. These measures may be administered in person or online.

Behavioral Measures

Behavioral measures involve measuring participants’ behavior directly, such as through reaction time tasks or performance tests. These measures may be administered using specialized equipment or software.

Physiological Measures

Physiological measures involve measuring participants’ physiological responses, such as heart rate, blood pressure, or brain activity, using specialized equipment. These measures may be invasive or non-invasive, and may be administered in a laboratory or clinical setting.

Archival Data

Archival data involves using existing records or data, such as medical records, administrative records, or historical documents, as a source of information. These data may be collected from public or private sources.

Computerized Measures

Computerized measures involve using software or computer programs to collect data on participants’ behavior or responses. These measures may include reaction time tasks, cognitive tests, or other types of computer-based assessments.

Video Recording

Video recording involves recording participants’ behavior or interactions using cameras or other recording equipment. This method can be used to capture detailed information about participants’ behavior or to analyze social interactions.

Data Analysis Method

Experimental design data analysis methods refer to the statistical techniques and procedures used to analyze data collected in experimental research. Here are some common experimental design data analysis methods:

Descriptive Statistics

Descriptive statistics are used to summarize and describe the data collected in the study. This includes measures such as mean, median, mode, range, and standard deviation.

Inferential Statistics

Inferential statistics are used to make inferences or generalizations about a larger population based on the data collected in the study. This includes hypothesis testing and estimation.

Analysis of Variance (ANOVA)

ANOVA is a statistical technique used to compare means across two or more groups in order to determine whether there are significant differences between the groups. There are several types of ANOVA, including one-way ANOVA, two-way ANOVA, and repeated measures ANOVA.

Regression Analysis

Regression analysis is used to model the relationship between two or more variables in order to determine the strength and direction of the relationship. There are several types of regression analysis, including linear regression, logistic regression, and multiple regression.

Factor Analysis

Factor analysis is used to identify underlying factors or dimensions in a set of variables. This can be used to reduce the complexity of the data and identify patterns in the data.

Structural Equation Modeling (SEM)

SEM is a statistical technique used to model complex relationships between variables. It can be used to test complex theories and models of causality.

Cluster Analysis

Cluster analysis is used to group similar cases or observations together based on similarities or differences in their characteristics.

Time Series Analysis

Time series analysis is used to analyze data collected over time in order to identify trends, patterns, or changes in the data.

Multilevel Modeling

Multilevel modeling is used to analyze data that is nested within multiple levels, such as students nested within schools or employees nested within companies.

Applications of Experimental Design 

Experimental design is a versatile research methodology that can be applied in many fields. Here are some applications of experimental design:

• Medical Research: Experimental design is commonly used to test new treatments or medications for various medical conditions. This includes clinical trials to evaluate the safety and effectiveness of new drugs or medical devices.
• Agriculture : Experimental design is used to test new crop varieties, fertilizers, and other agricultural practices. This includes randomized field trials to evaluate the effects of different treatments on crop yield, quality, and pest resistance.
• Environmental science: Experimental design is used to study the effects of environmental factors, such as pollution or climate change, on ecosystems and wildlife. This includes controlled experiments to study the effects of pollutants on plant growth or animal behavior.
• Psychology : Experimental design is used to study human behavior and cognitive processes. This includes experiments to test the effects of different interventions, such as therapy or medication, on mental health outcomes.
• Engineering : Experimental design is used to test new materials, designs, and manufacturing processes in engineering applications. This includes laboratory experiments to test the strength and durability of new materials, or field experiments to test the performance of new technologies.
• Education : Experimental design is used to evaluate the effectiveness of teaching methods, educational interventions, and programs. This includes randomized controlled trials to compare different teaching methods or evaluate the impact of educational programs on student outcomes.
• Marketing : Experimental design is used to test the effectiveness of marketing campaigns, pricing strategies, and product designs. This includes experiments to test the impact of different marketing messages or pricing schemes on consumer behavior.

Examples of Experimental Design 

Here are some examples of experimental design in different fields:

• Example in Medical research : A study that investigates the effectiveness of a new drug treatment for a particular condition. Patients are randomly assigned to either a treatment group or a control group, with the treatment group receiving the new drug and the control group receiving a placebo. The outcomes, such as improvement in symptoms or side effects, are measured and compared between the two groups.
• Example in Education research: A study that examines the impact of a new teaching method on student learning outcomes. Students are randomly assigned to either a group that receives the new teaching method or a group that receives the traditional teaching method. Student achievement is measured before and after the intervention, and the results are compared between the two groups.
• Example in Environmental science: A study that tests the effectiveness of a new method for reducing pollution in a river. Two sections of the river are selected, with one section treated with the new method and the other section left untreated. The water quality is measured before and after the intervention, and the results are compared between the two sections.
• Example in Marketing research: A study that investigates the impact of a new advertising campaign on consumer behavior. Participants are randomly assigned to either a group that is exposed to the new campaign or a group that is not. Their behavior, such as purchasing or product awareness, is measured and compared between the two groups.
• Example in Social psychology: A study that examines the effect of a new social intervention on reducing prejudice towards a marginalized group. Participants are randomly assigned to either a group that receives the intervention or a control group that does not. Their attitudes and behavior towards the marginalized group are measured before and after the intervention, and the results are compared between the two groups.

When to use Experimental Research Design 

Experimental research design should be used when a researcher wants to establish a cause-and-effect relationship between variables. It is particularly useful when studying the impact of an intervention or treatment on a particular outcome.

Here are some situations where experimental research design may be appropriate:

• When studying the effects of a new drug or medical treatment: Experimental research design is commonly used in medical research to test the effectiveness and safety of new drugs or medical treatments. By randomly assigning patients to treatment and control groups, researchers can determine whether the treatment is effective in improving health outcomes.
• When evaluating the effectiveness of an educational intervention: An experimental research design can be used to evaluate the impact of a new teaching method or educational program on student learning outcomes. By randomly assigning students to treatment and control groups, researchers can determine whether the intervention is effective in improving academic performance.
• When testing the effectiveness of a marketing campaign: An experimental research design can be used to test the effectiveness of different marketing messages or strategies. By randomly assigning participants to treatment and control groups, researchers can determine whether the marketing campaign is effective in changing consumer behavior.
• When studying the effects of an environmental intervention: Experimental research design can be used to study the impact of environmental interventions, such as pollution reduction programs or conservation efforts. By randomly assigning locations or areas to treatment and control groups, researchers can determine whether the intervention is effective in improving environmental outcomes.
• When testing the effects of a new technology: An experimental research design can be used to test the effectiveness and safety of new technologies or engineering designs. By randomly assigning participants or locations to treatment and control groups, researchers can determine whether the new technology is effective in achieving its intended purpose.

How to Conduct Experimental Research

Here are the steps to conduct Experimental Research:

• Identify a Research Question : Start by identifying a research question that you want to answer through the experiment. The question should be clear, specific, and testable.
• Develop a Hypothesis: Based on your research question, develop a hypothesis that predicts the relationship between the independent and dependent variables. The hypothesis should be clear and testable.
• Design the Experiment : Determine the type of experimental design you will use, such as a between-subjects design or a within-subjects design. Also, decide on the experimental conditions, such as the number of independent variables, the levels of the independent variable, and the dependent variable to be measured.
• Select Participants: Select the participants who will take part in the experiment. They should be representative of the population you are interested in studying.
• Randomly Assign Participants to Groups: If you are using a between-subjects design, randomly assign participants to groups to control for individual differences.
• Conduct the Experiment : Conduct the experiment by manipulating the independent variable(s) and measuring the dependent variable(s) across the different conditions.
• Analyze the Data: Analyze the data using appropriate statistical methods to determine if there is a significant effect of the independent variable(s) on the dependent variable(s).
• Draw Conclusions: Based on the data analysis, draw conclusions about the relationship between the independent and dependent variables. If the results support the hypothesis, then it is accepted. If the results do not support the hypothesis, then it is rejected.
• Communicate the Results: Finally, communicate the results of the experiment through a research report or presentation. Include the purpose of the study, the methods used, the results obtained, and the conclusions drawn.

Purpose of Experimental Design 

The purpose of experimental design is to control and manipulate one or more independent variables to determine their effect on a dependent variable. Experimental design allows researchers to systematically investigate causal relationships between variables, and to establish cause-and-effect relationships between the independent and dependent variables. Through experimental design, researchers can test hypotheses and make inferences about the population from which the sample was drawn.

Experimental design provides a structured approach to designing and conducting experiments, ensuring that the results are reliable and valid. By carefully controlling for extraneous variables that may affect the outcome of the study, experimental design allows researchers to isolate the effect of the independent variable(s) on the dependent variable(s), and to minimize the influence of other factors that may confound the results.

Experimental design also allows researchers to generalize their findings to the larger population from which the sample was drawn. By randomly selecting participants and using statistical techniques to analyze the data, researchers can make inferences about the larger population with a high degree of confidence.

Overall, the purpose of experimental design is to provide a rigorous, systematic, and scientific method for testing hypotheses and establishing cause-and-effect relationships between variables. Experimental design is a powerful tool for advancing scientific knowledge and informing evidence-based practice in various fields, including psychology, biology, medicine, engineering, and social sciences.

Advantages of Experimental Design 

Experimental design offers several advantages in research. Here are some of the main advantages:

• Control over extraneous variables: Experimental design allows researchers to control for extraneous variables that may affect the outcome of the study. By manipulating the independent variable and holding all other variables constant, researchers can isolate the effect of the independent variable on the dependent variable.
• Establishing causality: Experimental design allows researchers to establish causality by manipulating the independent variable and observing its effect on the dependent variable. This allows researchers to determine whether changes in the independent variable cause changes in the dependent variable.
• Replication : Experimental design allows researchers to replicate their experiments to ensure that the findings are consistent and reliable. Replication is important for establishing the validity and generalizability of the findings.
• Random assignment: Experimental design often involves randomly assigning participants to conditions. This helps to ensure that individual differences between participants are evenly distributed across conditions, which increases the internal validity of the study.
• Precision : Experimental design allows researchers to measure variables with precision, which can increase the accuracy and reliability of the data.
• Generalizability : If the study is well-designed, experimental design can increase the generalizability of the findings. By controlling for extraneous variables and using random assignment, researchers can increase the likelihood that the findings will apply to other populations and contexts.

Limitations of Experimental Design

Experimental design has some limitations that researchers should be aware of. Here are some of the main limitations:

• Artificiality : Experimental design often involves creating artificial situations that may not reflect real-world situations. This can limit the external validity of the findings, or the extent to which the findings can be generalized to real-world settings.
• Ethical concerns: Some experimental designs may raise ethical concerns, particularly if they involve manipulating variables that could cause harm to participants or if they involve deception.
• Participant bias : Participants in experimental studies may modify their behavior in response to the experiment, which can lead to participant bias.
• Limited generalizability: The conditions of the experiment may not reflect the complexities of real-world situations. As a result, the findings may not be applicable to all populations and contexts.
• Cost and time : Experimental design can be expensive and time-consuming, particularly if the experiment requires specialized equipment or if the sample size is large.
• Researcher bias : Researchers may unintentionally bias the results of the experiment if they have expectations or preferences for certain outcomes.
• Lack of feasibility : Experimental design may not be feasible in some cases, particularly if the research question involves variables that cannot be manipulated or controlled.

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A Complete Guide to Experimental Research

Published by Carmen Troy at August 14th, 2021 , Revised On August 25, 2023

A Quick Guide to Experimental Research

Experimental research refers to the experiments conducted in the laboratory or observation under controlled conditions. Researchers try to find out the cause-and-effect relationship between two or more variables. 

The subjects/participants in the experiment are selected and observed. They receive treatments such as changes in room temperature, diet, atmosphere, or given a new drug to observe the changes. Experiments can vary from personal and informal natural comparisons. It includes three  types of variables ;

• Independent variable
• Dependent variable
• Controlled variable

Before conducting experimental research, you need to have a clear understanding of the experimental design. A true experimental design includes  identifying a problem , formulating a  hypothesis , determining the number of variables, selecting and assigning the participants,  types of research designs , meeting ethical values, etc.

There are many  types of research  methods that can be classified based on:

• The nature of the problem to be studied
• Number of participants (individual or groups)
• Number of groups involved (Single group or multiple groups)
• Types of data collection methods (Qualitative/Quantitative/Mixed methods)
• Number of variables (single independent variable/ factorial two independent variables)
• The experimental design

Types of Experimental Research

Laboratory Experiment  

It is also called experimental research. This type of research is conducted in the laboratory. A researcher can manipulate and control the variables of the experiment.

Example: Milgram’s experiment on obedience.

Field Experiment

Field experiments are conducted in the participants’ open field and the environment by incorporating a few artificial changes. Researchers do not have control over variables under measurement. Participants know that they are taking part in the experiment.

Natural Experiments

The experiment is conducted in the natural environment of the participants. The participants are generally not informed about the experiment being conducted on them.

Examples: Estimating the health condition of the population. Did the increase in tobacco prices decrease the sale of tobacco? Did the usage of helmets decrease the number of head injuries of the bikers?

Quasi-Experiments

A quasi-experiment is an experiment that takes advantage of natural occurrences. Researchers cannot assign random participants to groups.

Example: Comparing the academic performance of the two schools.

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How to Conduct Experimental Research?

Step 1. identify and define the problem.

You need to identify a problem as per your field of study and describe your  research question .

Example: You want to know about the effects of social media on the behavior of youngsters. It would help if you found out how much time students spend on the internet daily.

Example: You want to find out the adverse effects of junk food on human health. It would help if you found out how junk food frequent consumption can affect an individual’s health.

Step 2. Determine the Number of Levels of Variables

You need to determine the number of  variables . The independent variable is the predictor and manipulated by the researcher. At the same time, the dependent variable is the result of the independent variable.

In the first example, we predicted that increased social media usage negatively correlates with youngsters’ negative behaviour.

In the second example, we predicted the positive correlation between a balanced diet and a good healthy and negative relationship between junk food consumption and multiple health issues.

Step 3. Formulate the Hypothesis

One of the essential aspects of experimental research is formulating a hypothesis . A researcher studies the cause and effect between the independent and dependent variables and eliminates the confounding variables. A  null hypothesis is when there is no significant relationship between the dependent variable and the participants’ independent variables. A researcher aims to disprove the theory. H0 denotes it.  The  Alternative hypothesis  is the theory that a researcher seeks to prove.  H1or HA denotes it. 

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Step 4. Selection and Assignment of the Subjects

It’s an essential feature that differentiates the experimental design from other research designs . You need to select the number of participants based on the requirements of your experiment. Then the participants are assigned to the treatment group. There should be a control group without any treatment to study the outcomes without applying any changes compared to the experimental group.

Randomisation:  The participants are selected randomly and assigned to the experimental group. It is known as probability sampling. If the selection is not random, it’s considered non-probability sampling.

Stratified sampling : It’s a type of random selection of the participants by dividing them into strata and randomly selecting them from each level. 

Matching:   Even though participants are selected randomly, they can be assigned to the various comparison groups. Another procedure for selecting the participants is ‘matching.’ The participants are selected from the controlled group to match the experimental groups’ participants in all aspects based on the dependent variables.  

What is Replicability?

When a researcher uses the same methodology  and subject groups to carry out the experiments, it’s called ‘replicability.’ The  results will be similar each time. Researchers usually replicate their own work to strengthen external validity.

Step 5. Select a Research Design

You need to select a  research design  according to the requirements of your experiment. There are many types of experimental designs as follows.

Step 6. Meet Ethical and Legal Requirements

• Participants of the research should not be harmed.
• The dignity and confidentiality of the research should be maintained.
• The consent of the participants should be taken before experimenting.
• The privacy of the participants should be ensured.
• Research data should remain confidential.
• The anonymity of the participants should be ensured.
• The rules and objectives of the experiments should be followed strictly.
• Any wrong information or data should be avoided.

Tips for Meeting the Ethical Considerations

To meet the ethical considerations, you need to ensure that.

• Participants have the right to withdraw from the experiment.
• They should be aware of the required information about the experiment.
• It would help if you avoided offensive or unacceptable language while framing the questions of interviews, questionnaires, or Focus groups.
• You should ensure the privacy and anonymity of the participants.
• You should acknowledge the sources and authors in your dissertation using any referencing styles such as APA/MLA/Harvard referencing style.

Step 7. Collect and Analyse Data.

Collect the data  by using suitable data collection according to your experiment’s requirement, such as observations,  case studies ,  surveys ,  interviews , questionnaires, etc. Analyse the obtained information.

Step 8. Present and Conclude the Findings of the Study.

Write the report of your research. Present, conclude, and explain the outcomes of your study .  

Frequently Asked Questions

What is the first step in conducting an experimental research.

The first step in conducting experimental research is to define your research question or hypothesis. Clearly outline the purpose and expectations of your experiment to guide the entire research process.

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Experimental Research Design — 6 mistakes you should never make!

Since school days’ students perform scientific experiments that provide results that define and prove the laws and theorems in science. These experiments are laid on a strong foundation of experimental research designs.

An experimental research design helps researchers execute their research objectives with more clarity and transparency.

In this article, we will not only discuss the key aspects of experimental research designs but also the issues to avoid and problems to resolve while designing your research study.

Table of Contents

What Is Experimental Research Design?

Experimental research design is a framework of protocols and procedures created to conduct experimental research with a scientific approach using two sets of variables. Herein, the first set of variables acts as a constant, used to measure the differences of the second set. The best example of experimental research methods is quantitative research .

Experimental research helps a researcher gather the necessary data for making better research decisions and determining the facts of a research study.

When Can a Researcher Conduct Experimental Research?

A researcher can conduct experimental research in the following situations —

• When time is an important factor in establishing a relationship between the cause and effect.
• When there is an invariable or never-changing behavior between the cause and effect.
• Finally, when the researcher wishes to understand the importance of the cause and effect.

Importance of Experimental Research Design

To publish significant results, choosing a quality research design forms the foundation to build the research study. Moreover, effective research design helps establish quality decision-making procedures, structures the research to lead to easier data analysis, and addresses the main research question. Therefore, it is essential to cater undivided attention and time to create an experimental research design before beginning the practical experiment.

By creating a research design, a researcher is also giving oneself time to organize the research, set up relevant boundaries for the study, and increase the reliability of the results. Through all these efforts, one could also avoid inconclusive results. If any part of the research design is flawed, it will reflect on the quality of the results derived.

Types of Experimental Research Designs

Based on the methods used to collect data in experimental studies, the experimental research designs are of three primary types:

1. Pre-experimental Research Design

A research study could conduct pre-experimental research design when a group or many groups are under observation after implementing factors of cause and effect of the research. The pre-experimental design will help researchers understand whether further investigation is necessary for the groups under observation.

Pre-experimental research is of three types —

• One-shot Case Study Research Design
• One-group Pretest-posttest Research Design
• Static-group Comparison

2. True Experimental Research Design

A true experimental research design relies on statistical analysis to prove or disprove a researcher’s hypothesis. It is one of the most accurate forms of research because it provides specific scientific evidence. Furthermore, out of all the types of experimental designs, only a true experimental design can establish a cause-effect relationship within a group. However, in a true experiment, a researcher must satisfy these three factors —

• There is a control group that is not subjected to changes and an experimental group that will experience the changed variables
• A variable that can be manipulated by the researcher
• Random distribution of the variables

This type of experimental research is commonly observed in the physical sciences.

3. Quasi-experimental Research Design

The word “Quasi” means similarity. A quasi-experimental design is similar to a true experimental design. However, the difference between the two is the assignment of the control group. In this research design, an independent variable is manipulated, but the participants of a group are not randomly assigned. This type of research design is used in field settings where random assignment is either irrelevant or not required.

The classification of the research subjects, conditions, or groups determines the type of research design to be used.

Advantages of Experimental Research

Experimental research allows you to test your idea in a controlled environment before taking the research to clinical trials. Moreover, it provides the best method to test your theory because of the following advantages:

• Researchers have firm control over variables to obtain results.
• The subject does not impact the effectiveness of experimental research. Anyone can implement it for research purposes.
• The results are specific.
• Post results analysis, research findings from the same dataset can be repurposed for similar research ideas.
• Researchers can identify the cause and effect of the hypothesis and further analyze this relationship to determine in-depth ideas.
• Experimental research makes an ideal starting point. The collected data could be used as a foundation to build new research ideas for further studies.

6 Mistakes to Avoid While Designing Your Research

There is no order to this list, and any one of these issues can seriously compromise the quality of your research. You could refer to the list as a checklist of what to avoid while designing your research.

1. Invalid Theoretical Framework

Usually, researchers miss out on checking if their hypothesis is logical to be tested. If your research design does not have basic assumptions or postulates, then it is fundamentally flawed and you need to rework on your research framework.

2. Inadequate Literature Study

Without a comprehensive research literature review , it is difficult to identify and fill the knowledge and information gaps. Furthermore, you need to clearly state how your research will contribute to the research field, either by adding value to the pertinent literature or challenging previous findings and assumptions.

3. Insufficient or Incorrect Statistical Analysis

Statistical results are one of the most trusted scientific evidence. The ultimate goal of a research experiment is to gain valid and sustainable evidence. Therefore, incorrect statistical analysis could affect the quality of any quantitative research.

4. Undefined Research Problem

This is one of the most basic aspects of research design. The research problem statement must be clear and to do that, you must set the framework for the development of research questions that address the core problems.

5. Research Limitations

Every study has some type of limitations . You should anticipate and incorporate those limitations into your conclusion, as well as the basic research design. Include a statement in your manuscript about any perceived limitations, and how you considered them while designing your experiment and drawing the conclusion.

6. Ethical Implications

The most important yet less talked about topic is the ethical issue. Your research design must include ways to minimize any risk for your participants and also address the research problem or question at hand. If you cannot manage the ethical norms along with your research study, your research objectives and validity could be questioned.

Experimental Research Design Example

In an experimental design, a researcher gathers plant samples and then randomly assigns half the samples to photosynthesize in sunlight and the other half to be kept in a dark box without sunlight, while controlling all the other variables (nutrients, water, soil, etc.)

By comparing their outcomes in biochemical tests, the researcher can confirm that the changes in the plants were due to the sunlight and not the other variables.

Experimental research is often the final form of a study conducted in the research process which is considered to provide conclusive and specific results. But it is not meant for every research. It involves a lot of resources, time, and money and is not easy to conduct, unless a foundation of research is built. Yet it is widely used in research institutes and commercial industries, for its most conclusive results in the scientific approach.

Have you worked on research designs? How was your experience creating an experimental design? What difficulties did you face? Do write to us or comment below and share your insights on experimental research designs!

Frequently Asked Questions

Randomization is important in an experimental research because it ensures unbiased results of the experiment. It also measures the cause-effect relationship on a particular group of interest.

Experimental research design lay the foundation of a research and structures the research to establish quality decision making process.

There are 3 types of experimental research designs. These are pre-experimental research design, true experimental research design, and quasi experimental research design.

The difference between an experimental and a quasi-experimental design are: 1. The assignment of the control group in quasi experimental research is non-random, unlike true experimental design, which is randomly assigned. 2. Experimental research group always has a control group; on the other hand, it may not be always present in quasi experimental research.

Experimental research establishes a cause-effect relationship by testing a theory or hypothesis using experimental groups or control variables. In contrast, descriptive research describes a study or a topic by defining the variables under it and answering the questions related to the same.

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143 Experiment Research Topics

Welcome to our collection of experimental research topics! Experiments are the cornerstone of empirical research, allowing scholars to test hypotheses and expand knowledge. With our experimental research questions ideas, you can uncover the diverse realms of empirical studies, from the natural sciences to social sciences and beyond.

🧪 7 Best Experimental Research Questions Ideas

🏆 best experimental research topics, 💡 simple experimental essay titles, 👍 catchy experimental research questions ideas, ❓ more experimental research questions ideas, 🎓 interesting experimental research topics.

• Bean Seed Germination Experiment Results
• Archimedes’ Principle Experiment: Determining Gravity of Objects
• Water Quality and Contamination Experiment Report
• Physical Health Indicator: Pulse Rate Experiment
• Static and Kinetic Friction: A Lab Experiment
• Human Transport Systems: The Pulse Rate Experiment
• Experiment: Flame Test and Chemical Fingerprinting
• “Stanford Prison Experiment Ethics” by Philip Zimbardo The primary purpose of Zimbardo’s work was to explore how quickly individuals would identify with corrections officers and prisoner roles during the prison simulation.
• Fiji Water Quality: Biology Lab Experiment Since Fiji water is among the popular brands in the US, it is essential to evaluate whether it is clean, that is, safe for human consumption.
• Kant’s Ethical Philosophy and Milgram’s Experiments The problem for Kant’s ethical philosophy is whether moral principles are applicable to nonhumans, such as Galacticans.
• Helicopter Experiment Assessment This report of a paper helicopter experiment involved designating a paper helicopter in varied designs and then dropping it severally while recording the flight time.
• Scientific Report Draft on Osmosis Egg Experiment Understanding how an egg reacts when placed in solutions of different concentrations enables one to understand the role of osmosis in the human body.
• Chemical Experiment on Enzyme Amylase This paper presents an experiment that was conducted to determine the activity of amylase on starch at various pH levels.
• Why People Obey Authority: Milgram Experiment and Real-World Situation Human beings would obey authority depending on the overall rewards, potential personal gains, and the consequences of failing to do so.
• Miles Davis and Steve Reich: Geniuses of Experiments and Creativity Although Miles Davis’ and Steve Reich’s music belongs to different genres, they are connected in their constant search for a new sound by experimenting and improvising.
• Should Animals Be Used for Scientific Experiments? Unfortunately, at the moment, the use of animals in science and medicine cannot be excluded entirely. However, it is possible to conduct experiments using mathematical models.
• Metal and Non-metal Redox Reactions Experiment The following experiment aimed to investigate Redox reaction and hence determine which elements were reactive; metal v. metal redox reactions, and non-metal v. non-metal reactions.
• John Watson and the “Little Albert” Experiment John Watson is considered to be the founder of behaviorism, a psychological theory that focuses on visible behavior while diminishing the notion of consciousness.
• Hawthorne Experiments – Elton Mayo With Roethlisberger and Dickson The Hawthorne theories have brought about a positive change in the behavior and attitude of the managers as well as the workers.
• Ideal Gas Expansion Law: Experiment The purpose of the experiment was to understand the differences between different types of ideal gas expansions, paying attention to the amount of work done.
• Unethical Research Experiments Violation of ethical principles can be traced in two analyzed cases; only in Landis’s experiment harm and killing were real in relation to animals.
• Conducting a Titration Experiment Titration studies are conducted to quantify the amount of an unidentified element in the sample using a methodological approach.
• Putnam’s “Twin Earth” Thought-Experiment Throughout the history of analytic philosophy, the problem of meaning has been and remains one of its central themes.
• “Tuskegee Syphilis Experiment – The Deadly Deception”: Unethical Scientific Experiment “Tuskegee Syphilis Experiment – The Deadly Deception” reviews an unethical scientific experiment on humans that was conducted by White physicians on African-Americans.
• The Power of Conformity: Asch’s Experiments The article examines a series of experiments by Asch that helped him identify the factors influencing social conformity.
• The Use of Animals in Psychological Experiments The method of experimentation is of great significance for multiple fields of psychology, especially for the behaviorist branch.
• Air Pressure Experiment Methods and Results The plastic mesh fabric was placed over the mouth of the Mason jar, and the metal screw band of the latter was fastened firmly over the plastic mesh sheet.
• Social Experiment: Informal Norms of Gender Issues The social experiment presents a contradiction between the socially-accepted norms and the understanding of equality between men and women.
• Psychology: Milgram Obedience Experiment Milgram’s experiment may be the last psychological experiment that has had a significant impact on psychology and public opinion.
• Ideal Experiment Design: Independent and Dependent Variables This work describes the ideal experiment, that is designed to verify the causal relationship between independent and dependent variables.
• Ethical Analysis of the Tuskegee Syphilis Experiments The Tuskegee Syphilis Study failed to take into account several critical ethical considerations. This essay examines some of the ethical problems linked to the investigation.
• Metrology Experiment with Measurement Tools The experiment concerned testing the efficacy of the measurement tools such as the Vernier caliper, a depth gauge, a micrometer, and a gauge in an uncertainty analysis.
• Osmosis Experiment With Parsnip Through Differing Concentration of Sucrose
• Identifying the Benefits of Home Ownership: A Swedish Experiment
• Experiment for Cancer Risk Factors
• Hydrochloric Acid Into Tubes of Water and Sodium Thiosulphate Experiment
• General Information about Monkey Drug Trials Experiment
• Reaction Rates Experiment Hydrochloric Acid
• Hydrochloric Acid and Marble Chips Experiment
• Physical Disability and Labor Market Discrimination: Evidence From a Field Experiment
• Canadian Advanced Nanosatellite Experiment Biology
• Dr. Heidegger’s Experiment: Reality or Illusion
• Experiment and Multi-Grid Modeling of Evacuation From a Classroom
• High-Performance Liquid Chromatography Experiment
• Social Capital and Contributions in a Public-Goods Experiment
• Illusory Gains From Chile’s Targeted School Voucher Experiment
• Short Selling and Earnings Management: A Controlled Experiment
• Theft and Rural Poverty: Results of a Natural Experiment
• Lab Experiment: The Effectiveness of Different Antibiotics on Bacteria
• Brucellosis and Its Treatment: Experiment With Doxycycline
• The Link Between Stanford Prison Experiment and Milgram Study
• Four Fundamental Results From the Mice Experiment
• Acoustics Experiment in Brunel’s Thames Tunnel In this project, tunnels that exist below London streets for a variety of communications, civil defense, and military purposes will be used as the objects of the experiment.
• Virtue Ethics in Stanford and Milgram’s Experiments This paper investigates the notion of virtue ethics, discussing two major studies, the Stanford prison experiment, and Milgram’s obedience studies.
• The Stanford Prison Experiment The Stanford prison experiment is an example of how outside social situations influence changes in thought and behavior among humans.
• Pasture Experiment: Fertiliser Treatments Response This work is an experiment that defines the role of fertilizers in pasture production and to establish the appropriate use of pasture sampling to assess pasture mass.
• Isopods and Their Use in Experiments Isopod is a large family belonging to the crayfish order. The fact that isopods are good to use in various experiments is related to their habitat.
• Inductor-Capacitor-Resistor Circuit Experiment The article presents the experiment that will demonstrate the relationship between an inductor, voltmeter, and resistor in an inductor-capacitor-resistor (LCR) circuit.
• P. Zimbardo’s Stanford Experiment A psychological experiment is an event conducted to acquire new scientific knowledge about psychology through the researcher’s deliberate intervention in the life of the examinee.
• Experiment on Effect of Energy Drinks on Athletic Performance Experimental research is a study that a researcher sets up to evaluate a given situation, such as a drug or treatment intervention.
• Stanford Prison Experiment: Behind the Mask Stanford Prison Experiment organized by Stanford researcher Philip Zimbardo led to a strong public response and still discussed today.
• A Hypothesis and an Experiment: A Case Study On the control experiment, there would be a seed grown at normal aeration, and wind conditions. All should have a viable bean seed planted centrally on watered soil preferably.
• Social Experiment: Wrong Outfit in a Wedding Event The attendees of the wedding event displayed disappointment, discomfort, and open resentment towards the dressing style.
• Situation, Institutional Norms, and Roles: The Stanford Experiment of Zimbardo Philip Zimbardo’s Stanford Experiment brought him critical acclaim. At the same time, it accorded him a certain level of notoriety; because of the methodologies he utilized to conduct the experiment.
• Scientific Experiments on Animals from Ethical Perspectives This paper discusses using animals in scientific experiments from the consequentialist, Kantian deontological and Donna Yarri’s Christian character-based perspectives.
• The Stanford Prison Experiment Analysis Abuse between guards and prisoners is an imminent factor attributed to the differential margin on duties and responsibilities.
• The Stanford Prison Experiment’s Historical Record The Stanford Prison Experiment is a seminal investigation into the dynamics of peer pressure in human psychology.
• Socioeconomic Status and Sentencing Severity Experiment There are two types of validity threats: external and internal. External validity refers to the degree to which the study can be applied to situations outside the research context.
• Psychology: Zimbardo Prison Experiment Despite all the horrors that contradict ethics, Zimbardo’s research contributed to the formation of social psychology. It was unethical to conduct this experiment.
• Post-Covid Adaptation Laboratory Experiment The goal of the laboratory experiment that this paper will outline is to test the hypothesis about the needs of senior citizens in the post-pandemic era.
• Predicting the Replicability of Social Science Lab Experiments The quality of work is the most significant factor for any academic organization. A research process for any scientific project requires careful evaluation of information sources.
• Moral Dilemma and Thought Experiments The aim of this essay is to set up a thought experiment in which a moral dilemma must be resolved. A person is invited to make a choice as a result of which people should suffer.
• Experiments in High-Frequency Trading High-frequency trading (HFT) is becoming increasingly popular with private businesses and traders. HFT allows traders to make transactions within fractions of seconds.
• The Ethical Issues in 1940’s U.S. Experiments With Syphilis in Guatemala The Guatemala tests have been viewed as a dark side of the U.S. clinical examination: in the 1940s, they purposely uncovered over 5,000 individuals with syphilis and gonorrhea.
• Sociological Experiment: The Salience of Social Norms Based on the sociological experiment described in the paper, the author demonstrated the salience of social norms that exist in our culture.
• Thought Experiment: The Morality of Human Actions A thought experiment aimed at assessing the morality of human actions motivated by divine punishment or reward raises the question of morality and religion correlation.
• Ethical Implications of the Early Studies in Psychology: Milgram’s Experiment Milgram’s experiment on obedience content and results are valuable for understanding the ethical issues that may occur in social and behavioral research.
• Blue-Eyed vs. Brown-Eyed Experiment Elliot exposed the learners to discrimination, in which blue-eyed children were initially preferred and given more privileges in the classroom than brown-eyed students.
• Experiment: Science Meets Real Life The experiment involves the sequential study of the dog’s behavior and its reaction to a change in some factors, such as food and bowl.
• Smoking: An Idea for a Statistical Experiment The hypothesis is that people who smoke cigarettes daily tend to earn more than others: this is a personal observation that requires careful experimental testing.
• The Stanford Jail Experiment Critiques One of the most important critiques leveled at the Stanford Jail Experiment is the length of time it took Zimbardo to call a halt to the experiment.
• Super Size Me and Jogn Cisna Experiments In comparison to Super Size Me, the experiment of John Cisna immediately stands out with a positive attitude towards fast food.
• The Milgram Experiment: Ethical Issues The Milgram experiment is a controversial study on the subject of obedience to authority figures. The participants were asked to deliver electric shocks to other people.
• Health and Medicine: Experiments and Discussions In the first experiment, researchers tested the subjectivity of polygraph examiners’ assessments. The specialist was given a specific name before the test began to do it.
• Can Nonrandomized Experiments Yield Accurate Answers?
• What Kind of Experiments Are Done on Animals?
• Is It Good to Use Animals for Experiments?
• What Are the Types of Experiments?
• Is There Any Healthy Way to Experiment With Drugs?
• What Are the Top Experiments of All Time?
• Are Breaching Experiments Ethical?
• What Does It Mean to Experiment With a Drug?
• Why Do We Use Factorial Experiments?
• How Does Temperature Affect the Rate of Reaction Experiment?
• What Are the Easiest Experiments to Do?
• How Can Rushing Harm the Data and the Experiment Overall?
• What Are the Steps to a Science Experiment?
• How Do Errors Affect the Experiment?
• What Is the Purpose of the Wax Experiment and What Conclusion Does Descartes Reach on Its Basis?
• Can an Experiment Be Invalid but Reliable?
• What Is the Most Influential Experiment in Psychology?
• Why Are Fruit Flies Used for Experiments?
• How Can You Improve the Accuracy of an Experiment?
• What Was Galileo’s Famous Cannonball Drop Experiment?
• What Can Knowledge Be Gained From Conducting a Breaching Experiment?
• How Do You Identify the Independent and Dependent Variables in an Experiment?
• What Was Griffith’s Experiment and Why Was It Important?
• What Is the Difference Between Contingent Valuation and Choice Experiment?
• What Is the Choice Experiment Valuation Method?
• An Experiment in DNA Cloning and Sequencing The aim of this experiment is to clone a fragment of DNA that includes the Green Fluorescent Protein (GFP) gene into the vector pTTQ18, which is an expression vector.
• Lab Experiment on Animals’ Taste or Smell Senses The hypothesis of the study is that taste perception and detection of different sugars by insects were similar to that of humans.
• An Enzyme Linked Immunosorbent Assay Experiment In our society presently, immunoassay techniques used in data analyses have assumed a place of high significance, particularly as it applies to pure/applied research.
• Anaerobic Threshold: An Experiment Anaerobic Threshold refers to the minimum level below which no increase in blood lactose can occur. At levels above AT, supplementing aerobic production needs aerobic energy.
• Comparative Effectiveness of Various Surfactants: Experiment Surfactants refer to chemical substances that lessen the surface tension in water. This experiment aimed at establishing the comparative effectiveness of various surfactants.
• An Experiment on Data Mining Extend This experiment aims to utilize knowledge and principles of data mining in depicting the investigation of emergent data in biology- particularly on the development of ELISAs.
• Bolted & Welded Connections and Tension Experiment Exploring and comparing the expected and actual failure modes of both bottled and welded connections in tension are the primary purposes of the paper.
• Lab Experiment on Photovoltaics The experiment was done specifically to ascertain how various connected units could be coordinated to give a more reliable and controllable functioning.
• Mind Control: Ethics of the Experiment The topics of mind control and free will has always been seen as a morally grey area in terms of its research potential.
• A Personal Behavior Modification Experiment Using Operant Conditioning This research paper points out the positive outcomes of swearing: it can relieve stress and help one cope with emotional work.
• Jane Elliott’s Experiment on Discrimination The teacher Jane Elliott from Iowa decided to conduct an experiment demonstrating to her students what discrimination is and what it feels like.
• The Tuskegee Syphilis Experiment When the Tuskegee Syphilis Experiment was begun, over 75 years ago, no such principles were officially in place.
• Extraneous Variables in Experiments There are some variables in experiments besides the independent variables that usually cause a variation or a change to the dependent variables.
• The Critical Characteristics of an Experiment The main aim of this assignment is to evaluate the thought control experiment by famous psychologist Ellen Langer and determine whether it is a qualitative experiment.
• Milgram Experiment: The Question of Ethics This essay will discuss the Milgram experiment and also argue that it was ethical as medical research standards were met, and no undue harm to the participants was caused.
• Boston’s Experiment: Harvard Business Review’s Lessons In Harvard Business Review’s Lessons from Boston’s Experiment with The One Fund, Mitchell discusses his experience with fund distribution to the victims of the Boston bombing.
• The Stanford Prison Experiment Review The video presents an experiment held in 1971. In general, a viewer can observe that people are subjected to behavior and opinion change when affected by others.
• The Way to Come To Terms With Yourself: Social Distancing Experiment In this work, the author describes the course and results of an experiment on social distance: refusal to use gadgets, any communication, and going out.
• Experiment: Bacteria vs Antibiotics The experiment aimed was to test the reaction of bacteria towards some antibiotics and determine the effectiveness of those antibiotics in treating some diseases.
• Ethics: Experiments on Animals Industrial and biomedical research is often painful and most of the test ends up killing the animals. Experiments such as these often incur the wrath of the animal rights movement.
• Impact of the Stanford Prison Experiment Have on Psychology This essay will begin with a brief description of Zimbardo’s Stanford Prison Experiment then it will move to explore two main issues that arose from the said experiment.
• Medical Pharmacology: The Langendorff Experiment The Langendorff experiment aimed at using an ex vivo isolated rat heart preparation to demonstrate the pharmacological effects of two unknown drugs.
• Studying Organisations: The Hawthorne Experiments The Hawthorn experiments marked a new direction in research of motivation and productivity. More than half a century has passed, and productivity remains a concern of management.
• Chemistry of Cooking. Saffron Rice Experiment This research project outlines an experiment that aims to determine the temperature at which Saffron rice turns yellow.
• Evaluation of the Stanford Prison Experiment’ Role The Stanford Prison Experiment is a study that was conducted on August 20, 1971 by a group of researchers headed by the psychology professor Philip Zimbardo.
• Heat Transfer Rates in a Hot Jet: Experiment The experiment is aimed at determining the heat transfer rates in a hot jet. The reasons for the hot jet to have different heat rates in different areas will be determined.
• Inattentive Blindness in Psychological Experiment The features of the human consciousness not to notice quite obvious changes are natural and innate. Such blindness can be caused by several factors.
• An Observable Experiment: Control Over the Variables An observable experiment is defined as the experiment in which the independent variables cannot possibly be controlled by the person or person setting the test.
• Tuskegee Syphilis Experiment: Ethical Controversy Tuskegee case set the background for the reconsideration of healthcare ethics, which means that the ethical value of the given case deserves reconsideration.
• Gender Stereotyping Experiment: The Level of Gender Stereotyping in Society The present study measures the effects of stereotyping women. It examines the first impression formed by subjects based on the information about a fictitious man or a woman.
• Psychological Studies and Experiments: Code of Conduct The following paper is based on past psychological studies i.e. Stanly Milgram’s ‘Obedience Experiment’, Philip Zimbardo’s ‘Stanford Prison Experiment, and Jane Elliott’s ‘Class Divided’.
• Using Animals in Medical Experiments This paper explores how the principles of the character-based ethical approach can be applied to the discussion of using animals in the medical research and experiments.
• The Stanford Experiment by Philip Zimbardo Philip Zimbardo’s Stanford Experiment shows that situational power and norms dictate the behavior of the individual more than the core beliefs that made up his personal identity.

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Experimental design: Guide, steps, examples

Last updated

27 April 2023

Reviewed by

Miroslav Damyanov

Short on time? Get an AI generated summary of this article instead

Experimental research design is a scientific framework that allows you to manipulate one or more variables while controlling the test environment. 

When testing a theory or new product, it can be helpful to have a certain level of control and manipulate variables to discover different outcomes. You can use these experiments to determine cause and effect or study variable associations. 

This guide explores the types of experimental design, the steps in designing an experiment, and the advantages and limitations of experimental design. 

Make research less tedious

Dovetail streamlines research to help you uncover and share actionable insights

• What is experimental research design?

You can determine the relationship between each of the variables by: 

Manipulating one or more independent variables (i.e., stimuli or treatments)

Applying the changes to one or more dependent variables (i.e., test groups or outcomes)

With the ability to analyze the relationship between variables and using measurable data, you can increase the accuracy of the result. 

What is a good experimental design?

A good experimental design requires: 

Significant planning to ensure control over the testing environment

Sound experimental treatments

Properly assigning subjects to treatment groups

Without proper planning, unexpected external variables can alter an experiment's outcome. 

To meet your research goals, your experimental design should include these characteristics:

Provide unbiased estimates of inputs and associated uncertainties

Enable the researcher to detect differences caused by independent variables

Include a plan for analysis and reporting of the results

Provide easily interpretable results with specific conclusions

What's the difference between experimental and quasi-experimental design?

The major difference between experimental and quasi-experimental design is the random assignment of subjects to groups. 

A true experiment relies on certain controls. Typically, the researcher designs the treatment and randomly assigns subjects to control and treatment groups. 

However, these conditions are unethical or impossible to achieve in some situations.

When it's unethical or impractical to assign participants randomly, that’s when a quasi-experimental design comes in. 

This design allows researchers to conduct a similar experiment by assigning subjects to groups based on non-random criteria. 

Another type of quasi-experimental design might occur when the researcher doesn't have control over the treatment but studies pre-existing groups after they receive different treatments.

When can a researcher conduct experimental research?

Various settings and professions can use experimental research to gather information and observe behavior in controlled settings. 

Basically, a researcher can conduct experimental research any time they want to test a theory with variable and dependent controls. 

Experimental research is an option when the project includes an independent variable and a desire to understand the relationship between cause and effect. 

• The importance of experimental research design

Experimental research enables researchers to conduct studies that provide specific, definitive answers to questions and hypotheses. 

Researchers can test Independent variables in controlled settings to:

Test the effectiveness of a new medication

Design better products for consumers

Answer questions about human health and behavior

Developing a quality research plan means a researcher can accurately answer vital research questions with minimal error. As a result, definitive conclusions can influence the future of the independent variable. 

Types of experimental research designs

There are three main types of experimental research design. The research type you use will depend on the criteria of your experiment, your research budget, and environmental limitations. 

Pre-experimental research design

A pre-experimental research study is a basic observational study that monitors independent variables’ effects. 

During research, you observe one or more groups after applying a treatment to test whether the treatment causes any change. 

The three subtypes of pre-experimental research design are:

One-shot case study research design

This research method introduces a single test group to a single stimulus to study the results at the end of the application. 

After researchers presume the stimulus or treatment has caused changes, they gather results to determine how it affects the test subjects. 

One-group pretest-posttest design

This method uses a single test group but includes a pretest study as a benchmark. The researcher applies a test before and after the group’s exposure to a specific stimulus. 

Static group comparison design

This method includes two or more groups, enabling the researcher to use one group as a control. They apply a stimulus to one group and leave the other group static. 

A posttest study compares the results among groups. 

True experimental research design

A true experiment is the most common research method. It involves statistical analysis to prove or disprove a specific hypothesis . 

Under completely experimental conditions, researchers expose participants in two or more randomized groups to different stimuli. 

Random selection removes any potential for bias, providing more reliable results. 

These are the three main sub-groups of true experimental research design:

Posttest-only control group design

This structure requires the researcher to divide participants into two random groups. One group receives no stimuli and acts as a control while the other group experiences stimuli.

Researchers perform a test at the end of the experiment to observe the stimuli exposure results.

Pretest-posttest control group design

This test also requires two groups. It includes a pretest as a benchmark before introducing the stimulus. 

The pretest introduces multiple ways to test subjects. For instance, if the control group also experiences a change, it reveals that taking the test twice changes the results.

Solomon four-group design

This structure divides subjects into two groups, with two as control groups. Researchers assign the first control group a posttest only and the second control group a pretest and a posttest. 

The two variable groups mirror the control groups, but researchers expose them to stimuli. The ability to differentiate between groups in multiple ways provides researchers with more testing approaches for data-based conclusions. 

Quasi-experimental research design

Although closely related to a true experiment, quasi-experimental research design differs in approach and scope. 

Quasi-experimental research design doesn’t have randomly selected participants. Researchers typically divide the groups in this research by pre-existing differences. 

Quasi-experimental research is more common in educational studies, nursing, or other research projects where it's not ethical or practical to use randomized subject groups.

• 5 steps for designing an experiment

Experimental research requires a clearly defined plan to outline the research parameters and expected goals. 

Here are five key steps in designing a successful experiment:

Step 1: Define variables and their relationship

Your experiment should begin with a question: What are you hoping to learn through your experiment? 

The relationship between variables in your study will determine your answer.

Define the independent variable (the intended stimuli) and the dependent variable (the expected effect of the stimuli). After identifying these groups, consider how you might control them in your experiment. 

Could natural variations affect your research? If so, your experiment should include a pretest and posttest. 

Step 2: Develop a specific, testable hypothesis

With a firm understanding of the system you intend to study, you can write a specific, testable hypothesis. 

What is the expected outcome of your study? 

Develop a prediction about how the independent variable will affect the dependent variable. 

How will the stimuli in your experiment affect your test subjects? 

Your hypothesis should provide a prediction of the answer to your research question . 

Step 3: Design experimental treatments to manipulate your independent variable

Depending on your experiment, your variable may be a fixed stimulus (like a medical treatment) or a variable stimulus (like a period during which an activity occurs). 

Determine which type of stimulus meets your experiment’s needs and how widely or finely to vary your stimuli. 

Step 4: Assign subjects to groups

When you have a clear idea of how to carry out your experiment, you can determine how to assemble test groups for an accurate study. 

When choosing your study groups, consider: 

The size of your experiment

Whether you can select groups randomly

Your target audience for the outcome of the study

You should be able to create groups with an equal number of subjects and include subjects that match your target audience. Remember, you should assign one group as a control and use one or more groups to study the effects of variables. 

Step 5: Plan how to measure your dependent variable

This step determines how you'll collect data to determine the study's outcome. You should seek reliable and valid measurements that minimize research bias or error. 

You can measure some data with scientific tools, while you’ll need to operationalize other forms to turn them into measurable observations.

• Advantages of experimental research

Experimental research is an integral part of our world. It allows researchers to conduct experiments that answer specific questions. 

While researchers use many methods to conduct different experiments, experimental research offers these distinct benefits:

Researchers can determine cause and effect by manipulating variables.

It gives researchers a high level of control.

Researchers can test multiple variables within a single experiment.

All industries and fields of knowledge can use it. 

Researchers can duplicate results to promote the validity of the study .

Replicating natural settings rapidly means immediate research.

Researchers can combine it with other research methods.

It provides specific conclusions about the validity of a product, theory, or idea.

• Disadvantages (or limitations) of experimental research

Unfortunately, no research type yields ideal conditions or perfect results. 

While experimental research might be the right choice for some studies, certain conditions could render experiments useless or even dangerous. 

Before conducting experimental research, consider these disadvantages and limitations:

Required professional qualification

Only competent professionals with an academic degree and specific training are qualified to conduct rigorous experimental research. This ensures results are unbiased and valid. 

Limited scope

Experimental research may not capture the complexity of some phenomena, such as social interactions or cultural norms. These are difficult to control in a laboratory setting.

Resource-intensive

Experimental research can be expensive, time-consuming, and require significant resources, such as specialized equipment or trained personnel.

Limited generalizability

The controlled nature means the research findings may not fully apply to real-world situations or people outside the experimental setting.

Practical or ethical concerns

Some experiments may involve manipulating variables that could harm participants or violate ethical guidelines . 

Researchers must ensure their experiments do not cause harm or discomfort to participants. 

Sometimes, recruiting a sample of people to randomly assign may be difficult. 

• Experimental research design example

Experiments across all industries and research realms provide scientists, developers, and other researchers with definitive answers. These experiments can solve problems, create inventions, and heal illnesses. 

Product design testing is an excellent example of experimental research. 

A company in the product development phase creates multiple prototypes for testing. With a randomized selection, researchers introduce each test group to a different prototype. 

When groups experience different product designs , the company can assess which option most appeals to potential customers. 

Experimental research design provides researchers with a controlled environment to conduct experiments that evaluate cause and effect. 

Using the five steps to develop a research plan ensures you anticipate and eliminate external variables while answering life’s crucial questions.

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10 Real-Life Experimental Research Examples

Chris Drew (PhD)

Dr. Chris Drew is the founder of the Helpful Professor. He holds a PhD in education and has published over 20 articles in scholarly journals. He is the former editor of the Journal of Learning Development in Higher Education. [Image Descriptor: Photo of Chris]

Learn about our Editorial Process

Experimental research is research that involves using a scientific approach to examine research variables.

Below are some famous experimental research examples. Some of these studies were conducted quite a long time ago. Some were so controversial that they would never be attempted today. And some were so unethical that they would never be permitted again.

A few of these studies have also had very practical implications for modern society involving criminal investigations, the impact of television and the media, and the power of authority figures.

Examples of Experimental Research

1. pavlov’s dog: classical conditioning.

Dr. Ivan Pavlov was a physiologist studying animal digestive systems in the 1890s. In one study, he presented food to a dog and then collected its salivatory juices via a tube attached to the inside of the animal’s mouth.

As he was conducting his experiments, an annoying thing kept happening; every time his assistant would enter the lab with a bowl of food for the experiment, the dog would start to salivate at the sound of the assistant’s footsteps.

Although this disrupted his experimental procedures, eventually, it dawned on Pavlov that something else was to be learned from this problem.

Pavlov learned that animals could be conditioned into responding on a physiological level to various stimuli, such as food, or even the sound of the assistant bringing the food down the hall.

Hence, the creation of the theory of classical conditioning. One of the most influential theories in psychology still to this day.

2. Bobo Doll Experiment: Observational Learning

Dr. Albert Bandura conducted one of the most influential studies in psychology in the 1960s at Stanford University.

His intention was to demonstrate that cognitive processes play a fundamental role in learning. At the time, Behaviorism was the predominant theoretical perspective, which completely rejected all inferences to constructs not directly observable .

So, Bandura made two versions of a video. In version #1, an adult behaved aggressively with a Bobo doll by throwing it around the room and striking it with a wooden mallet. In version #2, the adult played gently with the doll by carrying it around to different parts of the room and pushing it gently.

After showing children one of the two versions, they were taken individually to a room that had a Bobo doll. Their behavior was observed and the results indicated that children that watched version #1 of the video were far more aggressive than those that watched version #2.

Not only did Bandura’s Bobo doll study form the basis of his social learning theory, it also helped start the long-lasting debate about the harmful effects of television on children.

Worth Checking Out: What’s the Difference between Experimental and Observational Studies?

3. The Asch Study: Conformity  

Dr. Solomon Asch was interested in conformity and the power of group pressure. His study was quite simple. Different groups of students were shown lines of varying lengths and asked, “which line is longest.”

However, out of each group, only one was an actual participant. All of the others in the group were working with Asch and instructed to say that one of the shorter lines was actually the longest.

Nearly every time, the real participant gave an answer that was clearly wrong, but the same as the rest of the group.

The study is one of the most famous in psychology because it demonstrated the power of social pressure so clearly.  

4. Car Crash Experiment: Leading Questions

In 1974, Dr. Elizabeth Loftus and her undergraduate student John Palmer designed a study to examine how fallible human judgement is under certain conditions.

They showed groups of research participants videos that depicted accidents between two cars. Later, the participants were asked to estimate the rate of speed of the cars.

Here’s the interesting part. All participants were asked the same question with the exception of a single word: “How fast were the two cars going when they ______into each other?” The word in the blank varied in its implied severity.

Participants’ estimates were completely affected by the word in the blank. When the word “smashed” was used, participants estimated the cars were going much faster than when the word “contacted” was used. 

This line of research has had a huge impact on law enforcement interrogation practices, line-up procedures, and the credibility of eyewitness testimony .

5. The 6 Universal Emotions

The research by Dr. Paul Ekman has been influential in the study of emotions. His early research revealed that all human beings, regardless of culture, experience the same 6 basic emotions: happiness, sadness, disgust, fear, surprise, and anger.

In the late 1960s, Ekman traveled to Papua New Guinea. He approached a tribe of people that were extremely isolated from modern culture. With the help of a guide, he would describe different situations to individual members and take a photo of their facial expressions.

The situations included: if a good friend had come; their child had just died; they were about to get into a fight; or had just stepped on a dead pig.

The facial expressions of this highly isolated tribe were nearly identical to those displayed by people in his studies in California.

6. The Little Albert Study: Development of Phobias  

Dr. John Watson and Dr. Rosalie Rayner sought to demonstrate how irrational fears were developed.

Their study involved showing a white rat to an infant. Initially, the child had no fear of the rat. However, the researchers then began to create a loud noise each time they showed the child the rat by striking a steel bar with a hammer.

Eventually, the child started to cry and feared the white rat. The child also developed a fear of other white, furry objects such as white rabbits and a Santa’s beard.

This study is famous because it demonstrated one way in which phobias are developed in humans, and also because it is now considered highly unethical for its mistreatment of children, lack of study debriefing , and intent to instil fear.  

7. A Class Divided: Discrimination

Perhaps one of the most famous psychological experiments of all time was not conducted by a psychologist. In 1968, third grade teacher Jane Elliott conducted one of the most famous studies on discrimination in history. It took place shortly after the assassination of Dr. Martin Luther King, Jr.

She divided her class into two groups: brown-eyed and blue-eyed students. On the first day of the experiment, she announced the blue-eyed group as superior. They received extra privileges and were told not to intermingle with the brown-eyed students.

They instantly became happier, more self-confident, and started performing better academically.

The next day, the roles were reversed. The brown-eyed students were announced as superior and given extra privileges. Their behavior changed almost immediately and exhibited the same patterns as the other group had the day before.

This study was a remarkable demonstration of the harmful effects of discrimination.

8. The Milgram Study: Obedience to Authority

Dr. Stanley Milgram conducted one of the most influential experiments on authority and obedience in 1961 at Yale University.

Participants were told they were helping study the effects of punishment on learning. Their job was to administer an electric shock to another participant each time they made an error on a test. The other participant was actually an actor in another room that only pretended to be shocked.

However, each time a mistake was made, the level of shock was supposed to increase, eventually reaching quite high voltage levels. When the real participants expressed reluctance to administer the next level of shock, the experimenter, who served as the authority figure in the room, pressured the participant to deliver the next level of shock.

The results of this study were truly astounding. A surprisingly high percentage of participants continued to deliver the shocks to the highest level possible despite the very strong objections by the “other participant.”

This study demonstrated the power of authority figures.

9. The Marshmallow Test: Delay of Gratification

The Marshmallow Test was designed by Dr. Walter Mischel to examine the role of delay of gratification and academic success.

Children ages 4-6 years old were seated at a table with one marshmallow placed in front of them. The experimenter explained that if they did not eat the marshmallow, they would receive a second one. They could then eat both.

The children that were able to delay gratification the longest were rated as significantly more competent later in life and earned higher SAT scores than children that could not withstand the temptation.  

The study has since been conceptually replicated by other researchers that have revealed additional factors involved in delay of gratification and academic achievement.

10. Stanford Prison Study: Deindividuation

Dr. Philip Zimbardo conducted one of the most famous psychological studies of all time in 1971. The purpose of the study was to investigate how the power structure in some situations can lead people to behave in ways highly uncharacteristic of their usual behavior.

College students were recruited to participate in the study. Some were randomly assigned to play the role of prison guard. The others were actually “arrested” by real police officers. They were blindfolded and taken to the basement of the university’s psychology building which had been converted to look like a prison.

Although the study was supposed to last 2 weeks, it had to be halted due to the abusive actions of the guards.

The study demonstrated that people will behave in ways they never thought possible when placed in certain roles and power structures. Although the Stanford Prison Study is so well-known for what it revealed about human nature, it is also famous because of the numerous violations of ethical principles.

The studies above are varied and focused on many different aspects of human behavior . However, each example of experimental research listed above has had a lasting impact on society. Some have had tremendous sway in how very practical matters are conducted, such as criminal investigations and legal proceedings.

Psychology is a field of study that is often not fully understood by the general public. When most people hear the term “psychology,” they think of a therapist that listens carefully to the revealing statements of a patient. The therapist then tries to help their patient learn to cope with many of life’s challenges. Nothing wrong with that.

In reality however, most psychologists are researchers. They spend most of their time designing and conducting experiments to enhance our understanding of the human condition.

Asch SE. (1956). Studies of independence and conformity: I. A minority of one against a unanimous majority . Psychological Monographs: General and Applied, 70 (9),1-70. https://doi.org/doi:10.1037/h0093718

Bandura A. (1965). Influence of models’ reinforcement contingencies on the acquisition of imitative responses. Journal of Personality and Social Psychology, 1 (6), 589-595. https://doi.org/doi:10.1037/h0022070

Beck, H. P., Levinson, S., & Irons, G. (2009). Finding little Albert: A journey to John B. Watson’s infant laboratory.  American Psychologist, 64(7),  605-614.

Ekman, P. & Friesen, W. V. (1971).  Constants Across Cultures in the Face and motion .  Journal of Personality and Social Psychology, 17(2) , 124-129.

Loftus, E. F., & Palmer, J. C. (1974). Reconstruction of automobile destruction: An example of

the interaction between language and memory. Journal of Verbal Learning and Verbal

Behavior, 13 (5), 585–589.

Milgram S (1965). Some Conditions of Obedience and Disobedience to Authority. Human Relations, 18(1), 57–76.

Mischel, W., & Ebbesen, E. B. (1970). Attention in delay of gratification . Journal of Personality and Social Psychology, 16 (2), 329-337.

Pavlov, I.P. (1927). Conditioned Reflexes . London: Oxford University Press.

Watson, J. & Rayner, R. (1920). Conditioned emotional reactions.  Journal of Experimental Psychology, 3 , 1-14. Zimbardo, P., Haney, C., Banks, W. C., & Jaffe, D. (1971). The Stanford Prison Experiment: A simulation study of the psychology of imprisonment . Stanford University, Stanford Digital Repository, Stanford.

• Chris Drew (PhD) https://helpfulprofessor.com/author/chris-drew-phd/ 119 Bloom’s Taxonomy Examples
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200+ Experimental Quantitative Research Topics For STEM Students In 2023

STEM means Science, Technology, Engineering, and Math, which is not the only stuff we learn in school. It is like a treasure chest of skills that help students become great problem solvers, ready to tackle the real world’s challenges.

In this blog, we are here to explore the world of Research Topics for STEM Students. We will break down what STEM really means and why it is so important for students. In addition, we will give you the lowdown on how to pick a fascinating research topic. We will explain a list of 200+ Experimental Quantitative Research Topics For STEM Students.

And when it comes to writing a research title, we will guide you step by step. So, stay with us as we unlock the exciting world of STEM research – it is not just about grades; it is about growing smarter, more confident, and happier along the way.

What Is STEM?

Table of Contents

STEM is Science, Technology, Engineering, and Mathematics. It is a way of talking about things like learning, jobs, and activities related to these four important subjects. Science is about understanding the world around us, technology is about using tools and machines to solve problems, engineering is about designing and building things, and mathematics is about numbers and solving problems with them. STEM helps us explore, discover, and create cool stuff that makes our world better and more exciting.

Why STEM Research Is Important?

STEM research is important because it helps us learn new things about the world and solve problems. When scientists, engineers, and mathematicians study these subjects, they can discover cures for diseases, create new technology that makes life easier, and build things that help us live better. It is like a big puzzle where we put together pieces of knowledge to make our world safer, healthier, and more fun.

• STEM research leads to new discoveries and solutions.
• It helps find cures for diseases.
• STEM technology makes life easier.
• Engineers build things that improve our lives.
• Mathematics helps us understand and solve complex problems.

How to Choose a Topic for STEM Research Paper

Here are some steps to choose a topic for STEM Research Paper:

Step 1: Identify Your Interests

Think about what you like and what excites you in science, technology, engineering, or math. It could be something you learned in school, saw in the news, or experienced in your daily life. Choosing a topic you’re passionate about makes the research process more enjoyable.

Step 2: Research Existing Topics

Look up different STEM research areas online, in books, or at your library. See what scientists and experts are studying. This can give you ideas and help you understand what’s already known in your chosen field.

Step 3: Consider Real-World Problems

Think about the problems you see around you. Are there issues in your community or the world that STEM can help solve? Choosing a topic that addresses a real-world problem can make your research impactful.

Step 4: Talk to Teachers and Mentors

Discuss your interests with your teachers, professors, or mentors. They can offer guidance and suggest topics that align with your skills and goals. They may also provide resources and support for your research.

Step 5: Narrow Down Your Topic

Once you have some ideas, narrow them down to a specific research question or project. Make sure it’s not too broad or too narrow. You want a topic that you can explore in depth within the scope of your research paper.

Here we will discuss 200+ Experimental Quantitative Research Topics For STEM Students: 

Qualitative Research Topics for STEM Students:

Qualitative research focuses on exploring and understanding phenomena through non-numerical data and subjective experiences. Here are 10 qualitative research topics for STEM students:

• Exploring the experiences of female STEM students in overcoming gender bias in academia.
• Understanding the perceptions of teachers regarding the integration of technology in STEM education.
• Investigating the motivations and challenges of STEM educators in underprivileged schools.
• Exploring the attitudes and beliefs of parents towards STEM education for their children.
• Analyzing the impact of collaborative learning on student engagement in STEM subjects.
• Investigating the experiences of STEM professionals in bridging the gap between academia and industry.
• Understanding the cultural factors influencing STEM career choices among minority students.
• Exploring the role of mentorship in the career development of STEM graduates.
• Analyzing the perceptions of students towards the ethics of emerging STEM technologies like AI and CRISPR.
• Investigating the emotional well-being and stress levels of STEM students during their academic journey.

Easy Experimental Research Topics for STEM Students:

These experimental research topics are relatively straightforward and suitable for STEM students who are new to research:

•  Measuring the effect of different light wavelengths on plant growth.
•  Investigating the relationship between exercise and heart rate in various age groups.
•  Testing the effectiveness of different insulating materials in conserving heat.
•  Examining the impact of pH levels on the rate of chemical reactions.
•  Studying the behavior of magnets in different temperature conditions.
•  Investigating the effect of different concentrations of a substance on bacterial growth.
•  Testing the efficiency of various sunscreen brands in blocking UV radiation.
•  Measuring the impact of music genres on concentration and productivity.
•  Examining the correlation between the angle of a ramp and the speed of a rolling object.
•  Investigating the relationship between the number of blades on a wind turbine and energy output.

Research Topics for STEM Students in the Philippines:

These research topics are tailored for STEM students in the Philippines:

•  Assessing the impact of climate change on the biodiversity of coral reefs in the Philippines.
•  Studying the potential of indigenous plants in the Philippines for medicinal purposes.
•  Investigating the feasibility of harnessing renewable energy sources like solar and wind in rural Filipino communities.
•  Analyzing the water quality and pollution levels in major rivers and lakes in the Philippines.
•  Exploring sustainable agricultural practices for small-scale farmers in the Philippines.
•  Assessing the prevalence and impact of dengue fever outbreaks in urban areas of the Philippines.
•  Investigating the challenges and opportunities of STEM education in remote Filipino islands.
•  Studying the impact of typhoons and natural disasters on infrastructure resilience in the Philippines.
•  Analyzing the genetic diversity of endemic species in the Philippine rainforests.
•  Assessing the effectiveness of disaster preparedness programs in Philippine communities.

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Good Research Topics for STEM Students:

These research topics are considered good because they offer interesting avenues for investigation and learning:

•  Developing a low-cost and efficient water purification system for rural communities.
•  Investigating the potential use of CRISPR-Cas9 for gene therapy in genetic disorders.
•  Studying the applications of blockchain technology in securing medical records.
•  Analyzing the impact of 3D printing on customized prosthetics for amputees.
•  Exploring the use of artificial intelligence in predicting and preventing forest fires.
•  Investigating the effects of microplastic pollution on aquatic ecosystems.
•  Analyzing the use of drones in monitoring and managing agricultural crops.
•  Studying the potential of quantum computing in solving complex optimization problems.
•  Investigating the development of biodegradable materials for sustainable packaging.
•  Exploring the ethical implications of gene editing in humans.

Unique Research Topics for STEM Students:

Unique research topics can provide STEM students with the opportunity to explore unconventional and innovative ideas. Here are 10 unique research topics for STEM students:

•  Investigating the use of bioluminescent organisms for sustainable lighting solutions.
•  Studying the potential of using spider silk proteins for advanced materials in engineering.
•  Exploring the application of quantum entanglement for secure communication in the field of cryptography.
•  Analyzing the feasibility of harnessing geothermal energy from underwater volcanoes.
•  Investigating the use of CRISPR-Cas12 for rapid and cost-effective disease diagnostics.
•  Studying the interaction between artificial intelligence and human creativity in art and music generation.
•  Exploring the development of edible packaging materials to reduce plastic waste.
•  Investigating the impact of microgravity on cellular behavior and tissue regeneration in space.
•  Analyzing the potential of using sound waves to detect and combat invasive species in aquatic ecosystems.
•  Studying the use of biotechnology in reviving extinct species, such as the woolly mammoth.

Experimental Research Topics for STEM Students in the Philippines

Research topics for STEM students in the Philippines can address specific regional challenges and opportunities. Here are 10 experimental research topics for STEM students in the Philippines:

•  Assessing the effectiveness of locally sourced materials for disaster-resilient housing construction in typhoon-prone areas.
•  Investigating the utilization of indigenous plants for natural remedies in Filipino traditional medicine.
•  Studying the impact of volcanic soil on crop growth and agriculture in volcanic regions of the Philippines.
•  Analyzing the water quality and purification methods in remote island communities.
•  Exploring the feasibility of using bamboo as a sustainable construction material in the Philippines.
•  Investigating the potential of using solar stills for freshwater production in water-scarce regions.
•  Studying the effects of climate change on the migration patterns of bird species in the Philippines.
•  Analyzing the growth and sustainability of coral reefs in marine protected areas.
•  Investigating the utilization of coconut waste for biofuel production.
•  Studying the biodiversity and conservation efforts in the Tubbataha Reefs Natural Park.

Capstone Research Topics for STEM Students in the Philippines:

Capstone research projects are often more comprehensive and can address real-world issues. Here are 10 capstone research topics for STEM students in the Philippines:

•  Designing a low-cost and sustainable sanitation system for informal settlements in urban Manila.
•  Developing a mobile app for monitoring and reporting natural disasters in the Philippines.
•  Assessing the impact of climate change on the availability and quality of drinking water in Philippine cities.
•  Designing an efficient traffic management system to address congestion in major Filipino cities.
•  Analyzing the health implications of air pollution in densely populated urban areas of the Philippines.
•  Developing a renewable energy microgrid for off-grid communities in the archipelago.
•  Assessing the feasibility of using unmanned aerial vehicles (drones) for agricultural monitoring in rural Philippines.
•  Designing a low-cost and sustainable aquaponics system for urban agriculture.
•  Investigating the potential of vertical farming to address food security in densely populated urban areas.
•  Developing a disaster-resilient housing prototype suitable for typhoon-prone regions.

Experimental Quantitative Research Topics for STEM Students:

Experimental quantitative research involves the collection and analysis of numerical data to conclude. Here are 10 Experimental Quantitative Research Topics For STEM Students interested in experimental quantitative research:

•  Examining the impact of different fertilizers on crop yield in agriculture.
•  Investigating the relationship between exercise and heart rate among different age groups.
•  Analyzing the effect of varying light intensities on photosynthesis in plants.
•  Studying the efficiency of various insulation materials in reducing building heat loss.
•  Investigating the relationship between pH levels and the rate of corrosion in metals.
•  Analyzing the impact of different concentrations of pollutants on aquatic ecosystems.
•  Examining the effectiveness of different antibiotics on bacterial growth.
•  Trying to figure out how temperature affects how thick liquids are.
•  Finding out if there is a link between the amount of pollution in the air and lung illnesses in cities.
•  Analyzing the efficiency of solar panels in converting sunlight into electricity under varying conditions.

Descriptive Research Topics for STEM Students

Descriptive research aims to provide a detailed account or description of a phenomenon. Here are 10 topics for STEM students interested in descriptive research:

•  Describing the physical characteristics and behavior of a newly discovered species of marine life.
•  Documenting the geological features and formations of a particular region.
•  Creating a detailed inventory of plant species in a specific ecosystem.
•  Describing the properties and behavior of a new synthetic polymer.
•  Documenting the daily weather patterns and climate trends in a particular area.
•  Providing a comprehensive analysis of the energy consumption patterns in a city.
•  Describing the structural components and functions of a newly developed medical device.
•  Documenting the characteristics and usage of traditional construction materials in a region.
•  Providing a detailed account of the microbiome in a specific environmental niche.
•  Describing the life cycle and behavior of a rare insect species.

Research Topics for STEM Students in the Pandemic:

The COVID-19 pandemic has raised many research opportunities for STEM students. Here are 10 research topics related to pandemics:

•  Analyzing the effectiveness of various personal protective equipment (PPE) in preventing the spread of respiratory viruses.
•  Studying the impact of lockdown measures on air quality and pollution levels in urban areas.
•  Investigating the psychological effects of quarantine and social isolation on mental health.
•  Analyzing the genomic variation of the SARS-CoV-2 virus and its implications for vaccine development.
•  Studying the efficacy of different disinfection methods on various surfaces.
•  Investigating the role of contact tracing apps in tracking & controlling the spread of infectious diseases.
•  Analyzing the economic impact of the pandemic on different industries and sectors.
•  Studying the effectiveness of remote learning in STEM education during lockdowns.
•  Investigating the social disparities in healthcare access during a pandemic.
• Analyzing the ethical considerations surrounding vaccine distribution and prioritization.

Research Topics for STEM Students Middle School

Research topics for middle school STEM students should be engaging and suitable for their age group. Here are 10 research topics:

• Investigating the growth patterns of different types of mold on various food items.
• Studying the negative effects of music on plant growth and development.
• Analyzing the relationship between the shape of a paper airplane and its flight distance.
• Investigating the properties of different materials in making effective insulators for hot and cold beverages.
• Studying the effect of salt on the buoyancy of different objects in water.
• Analyzing the behavior of magnets when exposed to different temperatures.
• Investigating the factors that affect the rate of ice melting in different environments.
• Studying the impact of color on the absorption of heat by various surfaces.
• Analyzing the growth of crystals in different types of solutions.
• Investigating the effectiveness of different natural repellents against common pests like mosquitoes.

Technology Research Topics for STEM Students

Technology is at the forefront of STEM fields. Here are 10 research topics for STEM students interested in technology:

• Developing and optimizing algorithms for autonomous drone navigation in complex environments.
• Exploring the use of blockchain technology for enhancing the security and transparency of supply chains.
• Investigating the applications of virtual reality (VR) and augmented reality (AR) in medical training and surgery simulations.
• Studying the potential of 3D printing for creating personalized prosthetics and orthopedic implants.
• Analyzing the ethical and privacy implications of facial recognition technology in public spaces.
• Investigating the development of quantum computing algorithms for solving complex optimization problems.
• Explaining the use of machine learning and AI in predicting and mitigating the impact of natural disasters.
• Studying the advancement of brain-computer interfaces for assisting individuals with
• disabilities.
• Analyzing the role of wearable technology in monitoring and improving personal health and wellness.
• Investigating the use of robotics in disaster response and search and rescue operations.

Scientific Research Topics for STEM Students

Scientific research encompasses a wide range of topics. Here are 10 research topics for STEM students focusing on scientific exploration:

• Investigating the behavior of subatomic particles in high-energy particle accelerators.
• Studying the ecological impact of invasive species on native ecosystems.
• Analyzing the genetics of antibiotic resistance in bacteria and its implications for healthcare.
• Exploring the physics of gravitational waves and their detection through advanced interferometry.
• Investigating the neurobiology of memory formation and retention in the human brain.
• Studying the biodiversity and adaptation of extremophiles in harsh environments.
• Analyzing the chemistry of deep-sea hydrothermal vents and their potential for life beyond Earth.
• Exploring the properties of superconductors and their applications in technology.
• Investigating the mechanisms of stem cell differentiation for regenerative medicine.
• Studying the dynamics of climate change and its impact on global ecosystems.

Interesting Research Topics for STEM Students:

Engaging and intriguing research topics can foster a passion for STEM. Here are 10 interesting research topics for STEM students:

• Exploring the science behind the formation of auroras and their cultural significance.
• Investigating the mysteries of dark matter and dark energy in the universe.
• Studying the psychology of decision-making in high-pressure situations, such as sports or
• emergencies.
• Analyzing the impact of social media on interpersonal relationships and mental health.
• Exploring the potential for using genetic modification to create disease-resistant crops.
• Investigating the cognitive processes involved in solving complex puzzles and riddles.
• Studying the history and evolution of cryptography and encryption methods.
• Analyzing the physics of time travel and its theoretical possibilities.
• Exploring the role of Artificial Intelligence  in creating art and music.
• Investigating the science of happiness and well-being, including factors contributing to life satisfaction.

Practical Research Topics for STEM Students

Practical research often leads to real-world solutions. Here are 10 practical research topics for STEM students:

• Developing an affordable and sustainable water purification system for rural communities.
• Designing a low-cost, energy-efficient home heating and cooling system.
• Investigating strategies for reducing food waste in the supply chain and households.
• Studying the effectiveness of eco-friendly pest control methods in agriculture.
• Analyzing the impact of renewable energy integration on the stability of power grids.
• Developing a smartphone app for early detection of common medical conditions.
• Investigating the feasibility of vertical farming for urban food production.
• Designing a system for recycling and upcycling electronic waste.
• Studying the environmental benefits of green roofs and their potential for urban heat island mitigation.
• Analyzing the efficiency of alternative transportation methods in reducing carbon emissions.

Experimental Research Topics for STEM Students About Plants

Plants offer a rich field for experimental research. Here are 10 experimental research topics about plants for STEM students:

• Investigating the effect of different light wavelengths on plant growth and photosynthesis.
• Studying the impact of various fertilizers and nutrient solutions on crop yield.
• Analyzing the response of plants to different types and concentrations of plant hormones.
• Investigating the role of mycorrhizal in enhancing nutrient uptake in plants.
• Studying the effects of drought stress and water scarcity on plant physiology and adaptation mechanisms.
• Analyzing the influence of soil pH on plant nutrient availability and growth.
• Investigating the chemical signaling and defense mechanisms of plants against herbivores.
• Studying the impact of environmental pollutants on plant health and genetic diversity.
• Analyzing the role of plant secondary metabolites in pharmaceutical and agricultural applications.
• Investigating the interactions between plants and beneficial microorganisms in the rhizosphere.

Qualitative Research Topics for STEM Students in the Philippines

Qualitative research in the Philippines can address local issues and cultural contexts. Here are 10 qualitative research topics for STEM students in the Philippines:

• Exploring indigenous knowledge and practices in sustainable agriculture in Filipino communities.
• Studying the perceptions and experiences of Filipino fishermen in coping with climate change impacts.
• Analyzing the cultural significance and traditional uses of medicinal plants in indigenous Filipino communities.
• Investigating the barriers and facilitators of STEM education access in remote Philippine islands.
• Exploring the role of traditional Filipino architecture in natural disaster resilience.
• Studying the impact of indigenous farming methods on soil conservation and fertility.
• Analyzing the cultural and environmental significance of mangroves in coastal Filipino regions.
• Investigating the knowledge and practices of Filipino healers in treating common ailments.
• Exploring the cultural heritage and conservation efforts of the Ifugao rice terraces.
• Studying the perceptions and practices of Filipino communities in preserving marine biodiversity.

Science Research Topics for STEM Students

Science offers a diverse range of research avenues. Here are 10 science research topics for STEM students:

• Investigating the potential of gene editing techniques like CRISPR-Cas9 in curing genetic diseases.
• Studying the ecological impacts of species reintroduction programs on local ecosystems.
• Analyzing the effects of microplastic pollution on aquatic food webs and ecosystems.
• Investigating the link between air pollution and respiratory health in urban populations.
• Studying the role of epigenetics in the inheritance of acquired traits in organisms.
• Analyzing the physiology and adaptations of extremophiles in extreme environments on Earth.
• Investigating the genetics of longevity and factors influencing human lifespan.
• Studying the behavioral ecology and communication strategies of social insects.
• Analyzing the effects of deforestation on global climate patterns and biodiversity loss.
• Investigating the potential of synthetic biology in creating bioengineered organisms for beneficial applications.

Correlational Research Topics for STEM Students

Correlational research focuses on relationships between variables. Here are 10 correlational research topics for STEM students:

• Analyzing the correlation between dietary habits and the incidence of chronic diseases.
• Studying the relationship between exercise frequency and mental health outcomes.
• Investigating the correlation between socioeconomic status and access to quality healthcare.
• Analyzing the link between social media usage and self-esteem in adolescents.
• Studying the correlation between academic performance and sleep duration among students.
• Investigating the relationship between environmental factors and the prevalence of allergies.
• Analyzing the correlation between technology use and attention span in children.
• Studying how environmental factors are related to the frequency of allergies.
• Investigating the link between parental involvement in education and student achievement.
• Analyzing the correlation between temperature fluctuations and wildlife migration patterns.

Quantitative Research Topics for STEM Students in the Philippines

Quantitative research in the Philippines can address specific regional issues. Here are 10 quantitative research topics for STEM students in the Philippines

• Analyzing the impact of typhoons on coastal erosion rates in the Philippines.
• Studying the quantitative effects of land use change on watershed hydrology in Filipino regions.
• Investigating the quantitative relationship between deforestation and habitat loss for endangered species.
• Analyzing the quantitative patterns of marine biodiversity in Philippine coral reef ecosystems.
• Studying the quantitative assessment of water quality in major Philippine rivers and lakes.
• Investigating the quantitative analysis of renewable energy potential in specific Philippine provinces.
• Analyzing the quantitative impacts of agricultural practices on soil health and fertility.
• Studying the quantitative effectiveness of mangrove restoration in coastal protection in the Philippines.
• Investigating the quantitative evaluation of indigenous agricultural practices for sustainability.
• Analyzing the quantitative patterns of air pollution and its health impacts in urban Filipino areas.

Things That Must Keep In Mind While Writing Quantitative Research Title 

Here are few things that must be keep in mind while writing quantitative research tile:

1. Be Clear and Precise

Make sure your research title is clear and says exactly what your study is about. People should easily understand the topic and goals of your research by reading the title.

2. Use Important Words

Include words that are crucial to your research, like the main subjects, who you’re studying, and how you’re doing your research. This helps others find your work and understand what it’s about.

3. Avoid Confusing Words

Stay away from words that might confuse people. Your title should be easy to grasp, even if someone isn’t an expert in your field.

4. Show Your Research Approach

Tell readers what kind of research you did, like experiments or surveys. This gives them a hint about how you conducted your study.

5. Match Your Title with Your Research Questions

Make sure your title matches the questions you’re trying to answer in your research. It should give a sneak peek into what your study is all about and keep you on the right track as you work on it.

STEM students, addressing what STEM is and why research matters in this field. It offered an extensive list of research topics , including experimental, qualitative, and regional options, catering to various academic levels and interests. Whether you’re a middle school student or pursuing advanced studies, these topics offer a wealth of ideas. The key takeaway is to choose a topic that resonates with your passion and aligns with your goals, ensuring a successful journey in STEM research. Choose the best Experimental Quantitative Research Topics For Stem Students today!

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What is Experimental Research: Definition, Types & Examples

Understand how experimental research enables researchers to confidently identify causal relationships between variables and validate findings, enhancing credibility.

June 16, 2024

In this Article

Experimental research is crucial for companies because it allows them to precisely control and measure key factors, identify dependent and independent elements, and set conditions to observe their effects. By changing one variable systematically, it is possible to determine possible cause-and-effect relations and analyze how specific observed effects depend on them. 

Read this blog to learn more about how experimental research design can drive business success and provide practical examples of its application in various industries.

What is Experimental Research?

Experimental research is a systematic and scientific approach in which the researcher manipulates one or more independent variables and observes the effect on a dependent variable while controlling for extraneous variables. This method allows for the establishment of cause-and-effect relationships between variables. 

Experimental research involves using control groups, random assignment, and standardized procedures to ensure the reliability and validity of the results. It is commonly used in psychology, medicine, and the social sciences to test hypotheses and theories under controlled conditions.

Example of Experimental Research

An experimental research example scenario can be a clinical trial for a new medication. This scenario aims to determine whether the new type of drug applies to the patient. Accordingly, patients with hypertension diagnosed by a medical practitioner are randomly assigned to two groups. 

The experimental group is subjected to the new medication the research treatment facility delivers. In contrast, the control group is treated with either a placebo or the medical drugs previously used by the patients. The data will be both quantitative and qualitative . 

Quantitative data will include blood pressure levels or symptom severity scores. Qualitative data will include symptoms reported by the patient or symptoms observed by the practitioner and side effects experienced by the patients. Consequently, the research on which type of drug is effective is tested, and results are obtained by comparing the patient's conditions in the two groups.

Researchers believe a new medication works if the experimental group shows significant symptom improvements compared to a control group and has no immediate side effects. Testing many patients increases confidence that the effects are due to the medication and not a placebo effect.

What Are The Different Types of Experimental Research?

The following are the different types of experimental research: Pre-Experimental Research

• One-Shot Case Study: A single group is exposed to a treatment and then observed for outcomes. There is no control group for comparison.
• One-Group Pretest-Posttest Design: A single group is measured before and after treatment to observe changes.

True Experimental Research

• Randomized Controlled Trials (RCT): Participants are randomly assigned to experimental and control groups to ensure comparability and reduce bias. This design is considered the gold standard in experimental research.
• Pretest-Posttest Control Group Design: Both the experimental and control groups are measured before and after the treatment. The experimental group receives the treatment, while the control group does not.
• Posttest-Only Control Group Design: Participants are randomly assigned to experimental and control groups, but measurements are taken only after the treatment is administered to the experimental group.

Quasi-Experimental Research

• Non-Equivalent Groups Design: Similar to the pretest-posttest control group design, participants are not randomly assigned to groups. This design is often used when random assignment is not feasible.
• Interrupted Time Series Design: Multiple measurements are taken before and after a treatment to observe changes over time. This design helps control time-related variables.
• Matched Groups Design: Participants are matched based on certain characteristics before being assigned to experimental and control groups, ensuring comparable groups.

Factorial Design

• Full Factorial Design: Involves manipulating two or more independent variables simultaneously to observe their interaction effects on the dependent variable. All possible combinations of the independent variables are tested.
• Fractional Factorial Design: A subset of the possible combinations of independent variables is tested, making it more practical when dealing with many variables.

What is the Importance of Experimental Research?

Establishing Causality

Experimental research is essential for establishing correlations between variables of interest and demonstrating causality. It allows researchers to manipulate one or more independent variables considered the cause and record changes in the dependent variable, the effect.

Controlling Variables

One of the strengths of this type of research is that it allows for controlling the effect of extraneous variables. This means that experimental research reduces alternative explanations of effects. Using control groups and random assignment to conditions, the experimental method can accurately determine whether the observed group differences resulted from manipulating the independent variable or other factors.

Providing Reliable and Valid Results

A structured and rigorous methodology while conducting experimental research minimizes the possibility of measurement errors and biases. In addition, randomized controlled trials are generally accepted as the gold standard in research. Because of these features, the data’s reliability can be confirmed in advance by similar findings, and the results will also be more replicable and generalizable to the broader population.

Informing Decision-Making

Experimental research provides empirical evidence and data to support important organizational decisions, such as product testing and experimentation, marketing strategies, or improving operational processes and activities.

Driving Innovation

Experimental research drives innovation by systematically testing new ideas and interventions. It allows companies and researchers to experiment with novel concepts in a controlled environment, identify successful innovations, and confidently scale them up.

What Are The Disadvantages of Experimental Research?

Ethical concerns.

Experimental research implies ethical dilemmas, especially when human subjects are concerned. Generally speaking, ethical principles prohibit manipulating variables, specifically intentionally causing harm to, offending, and inducing psychological or physical pressure. Ethics guidelines and review boards are expected to curb risks in an experiment, but they could also somewhat restrain findings. 

Artificial Settings

Most experimental studies are conducted in highly controlled artificial conditions, such as laboratories, where external variables are properly controlled and isolated. Thus, the conclusions of the findings might only sometimes be extended to the real world, so they will only sometimes be applicable. The main type of validity under which this problem falls is external validity. Some variables cannot be controlled or do not appear in artificial conditions. 

High Costs and Time Consumption

Experimental research is expensive and time-consuming. There are various reasons for this statement. First, such a type of research requires specialized equipment, controlled conditions of measurement, and large sample sizes, which means increased costs. Second, designing an experiment, preparing all the necessary information and tools for its implementation, running it, and analyzing the data received is usually time-consuming, even in the simplest cases. 

Practical and Logistical Constraints

Some variables or phenomena cannot be either manipulated or controlled. Experimental studies are impractical if processes are complex, large-scale, or long-term. For example, a lab cannot treat anything related to the environment or societal changes. Therefore, due to the inability to conduct experiments based on such phenomena, some questions can only be studied by other experimental research methods, such as observational or correlational.

Participant Behavior and Bias

Experimental studies may be biased based on the participants’ awareness of being observed during the process. Also called the Hawthorne effect, another issue that can hurt the study’s validity, especially in medical research, is using control groups. Although they are necessary to measure the efficiency of a certain treatment, such research may involve not providing some groups with potentially beneficial treatment. 

These two problems may affect the results and make them unethical. In either case, corrective steps should be taken to address this issue and ensure that the results have been obtained properly.

How Businesses Can Leverage Experimental Research?

Product development and testing.

Businesses can use experimental research to test new products or features before launching them. By creating controlled experiments, such as A/B testing , companies can compare different versions of a product to see which one performs better in terms of customer satisfaction, usability, and sales. This approach allows businesses to refine their products based on empirical evidence, reducing the risk of failure upon release.

Marketing Strategy Optimization

Experimental research is invaluable for optimizing marketing strategies. Businesses can test different marketing messages, channels, and tactics to determine which are most effective in engaging their target audience and driving conversions. For example, they can conduct randomized controlled trials to compare the impact of various advertising campaigns on consumer behavior , enabling data-driven decisions that enhance marketing ROI.

Customer Experience Enhancement

Customer experience is increasingly more critical for retention and loyalty. Companies use experimental research to determine the best practices for customer service, website design, and in-store experience. Through experimenting and measuring responses, companies can identify what promotes satisfaction and loyalty and apply these results to enhance customer experience.

Pricing Strategies

Experimental research helps businesses determine optimal pricing strategies. Companies can analyze consumer reactions and willingness to pay by testing different price points in controlled settings. This approach enables businesses to find the price that maximizes revenue without deterring customers, balancing profitability with market competitiveness.

Operational Efficiency

Businesses can use experimental research to enhance operational efficiency. For instance, they can test various processes, workflows, or technologies to identify which ones improve productivity, reduce costs, or enhance quality. Companies can implement the most effective strategies and practices by systematically experimenting with different operational changes, leading to better overall performance.

Final Words

Experimental research has become a powerful instrument for modern business development. It systematically tests assumptions and variables associated with various activities, from product development, marketing strategies, and customer experiences to pricing and operational efficiencies.

Get your hands on Decode , an AI-powered market research tool that can help you test hypotheses about consumer behavior and preferences. Companies can determine cause-and-effect relationships by manipulating specific variables, such as pricing or advertising methods, and observing the effects on consumer responses using Decode diary studies . 

This research method collects qualitative data on user behaviors, activities, and experiences over time. This helps them make informed decisions about product development, marketing strategies, and overall business operations.

Frequently Asked Questions (FAQs)

Question 1: what are examples of experimental research.

Answer: Examples of experimental research include drug trials, psychology experiments, and studies testing new teaching methods. These experiments involve manipulating variables and comparing outcomes to establish causal relationships.

Question 2: What is the meaning of experimental design in research?

Answer: Experimental design in research refers to the methodical planning of experiments to control variables, minimize bias, and draw valid conclusions. It involves carefully considering factors like sample size, randomization, and control groups.

Question 3: What are the characteristics of experimental research?

Answer: Characteristics of experimental research include manipulation of variables, random assignment, control groups, and measurement of outcomes. These features ensure that researchers can isolate the effects of specific variables and draw reliable conclusions.

Question 4: Where is experimental research used?

Answer: Experimental research is used in medicine, psychology, education, and natural sciences to investigate cause-and-effect relationships and validate hypotheses. It provides a systematic approach to testing theories and informing evidence-based practices.

Frequently Asked Questions

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Experimental Research: Meaning And Examples Of Experimental Research

Ever wondered why scientists across the world are being lauded for discovering the Covid-19 vaccine so early? It’s because every…

Ever wondered why scientists across the world are being lauded for discovering the Covid-19 vaccine so early? It’s because every government knows that vaccines are a result of experimental research design and it takes years of collected data to make one. It takes a lot of time to compare formulas and combinations with an array of possibilities across different age groups, genders and physical conditions. With their efficiency and meticulousness, scientists redefined the meaning of experimental research when they discovered a vaccine in less than a year.

What Is Experimental Research?

Characteristics of experimental research design, types of experimental research design, advantages and disadvantages of experimental research, examples of experimental research.

Experimental research is a scientific method of conducting research using two variables: independent and dependent. Independent variables can be manipulated to apply to dependent variables and the effect is measured. This measurement usually happens over a significant period of time to establish conditions and conclusions about the relationship between these two variables.

Experimental research is widely implemented in education, psychology, social sciences and physical sciences. Experimental research is based on observation, calculation, comparison and logic. Researchers collect quantitative data and perform statistical analyses of two sets of variables. This method collects necessary data to focus on facts and support sound decisions. It’s a helpful approach when time is a factor in establishing cause-and-effect relationships or when an invariable behavior is seen between the two.  

Now that we know the meaning of experimental research, let’s look at its characteristics, types and advantages.

The hypothesis is at the core of an experimental research design. Researchers propose a tentative answer after defining the problem and then test the hypothesis to either confirm or disregard it. Here are a few characteristics of experimental research:

• Dependent variables are manipulated or treated while independent variables are exerted on dependent variables as an experimental treatment. Extraneous variables are variables generated from other factors that can affect the experiment and contribute to change. Researchers have to exercise control to reduce the influence of these variables by randomization, making homogeneous groups and applying statistical analysis techniques.
• Researchers deliberately operate independent variables on the subject of the experiment. This is known as manipulation.
• Once a variable is manipulated, researchers observe the effect an independent variable has on a dependent variable. This is key for interpreting results.
• A researcher may want multiple comparisons between different groups with equivalent subjects. They may replicate the process by conducting sub-experiments within the framework of the experimental design.

Experimental research is equally effective in non-laboratory settings as it is in labs. It helps in predicting events in an experimental setting. It generalizes variable relationships so that they can be implemented outside the experiment and applied to a wider interest group.

The way a researcher assigns subjects to different groups determines the types of experimental research design .

Pre-experimental Research Design

In a pre-experimental research design, researchers observe a group or various groups to see the effect an independent variable has on the dependent variable to cause change. There is no control group as it is a simple form of experimental research . It’s further divided into three categories:

• A one-shot case study research design is a study where one dependent variable is considered. It’s a posttest study as it’s carried out after treating what presumably caused the change.
• One-group pretest-posttest design is a study that combines both pretest and posttest studies by testing a single group before and after administering the treatment.
• Static-group comparison involves studying two groups by subjecting one to treatment while the other remains static. After post-testing all groups the differences are observed.

This design is practical but lacks in certain areas of true experimental criteria.

True Experimental Research Design

This design depends on statistical analysis to approve or disregard a hypothesis. It’s an accurate design that can be conducted with or without a pretest on a minimum of two dependent variables assigned randomly. It is further classified into three types:

• The posttest-only control group design involves randomly selecting and assigning subjects to two groups: experimental and control. Only the experimental group is treated, while both groups are observed and post-tested to draw a conclusion from the difference between the groups.
• In a pretest-posttest control group design, two groups are randomly assigned subjects. Both groups are presented, the experimental group is treated and both groups are post-tested to measure how much change happened in each group.
• Solomon four-group design is a combination of the previous two methods. Subjects are randomly selected and assigned to four groups. Two groups are tested using each of the previous methods.

True experimental research design should have a variable to manipulate, a control group and random distribution.

With experimental research, we can test ideas in a controlled environment before marketing. It acts as the best method to test a theory as it can help in making predictions about a subject and drawing conclusions. Let’s look at some of the advantages that make experimental research useful:

• It allows researchers to have a stronghold over variables and collect desired results.
• Results are usually specific.
• The effectiveness of the research isn’t affected by the subject.
• Findings from the results usually apply to similar situations and ideas.
• Cause and effect of a hypothesis can be identified, which can be further analyzed for in-depth ideas.
• It’s the ideal starting point to collect data and lay a foundation for conducting further research and building more ideas.
• Medical researchers can develop medicines and vaccines to treat diseases by collecting samples from patients and testing them under multiple conditions.
• It can be used to improve the standard of academics across institutions by testing student knowledge and teaching methods before analyzing the result to implement programs.
• Social scientists often use experimental research design to study and test behavior in humans and animals.
• Software development and testing heavily depend on experimental research to test programs by letting subjects use a beta version and analyzing their feedback.

Even though it’s a scientific method, it has a few drawbacks. Here are a few disadvantages of this research method:

• Human error is a concern because the method depends on controlling variables. Improper implementation nullifies the validity of the research and conclusion.
• Eliminating extraneous variables (real-life scenarios) produces inaccurate conclusions.
• The process is time-consuming and expensive
• In medical research, it can have ethical implications by affecting patients’ well-being.
• Results are not descriptive and subjects can contribute to response bias.

Experimental research design is a sophisticated method that investigates relationships or occurrences among people or phenomena under a controlled environment and identifies the conditions responsible for such relationships or occurrences

Experimental research can be used in any industry to anticipate responses, changes, causes and effects. Here are some examples of experimental research :

• This research method can be used to evaluate employees’ skills. Organizations ask candidates to take tests before filling a post. It is used to screen qualified candidates from a pool of applicants. This allows organizations to identify skills at the time of employment. After training employees on the job, organizations further evaluate them to test impact and improvement. This is a pretest-posttest control group research example where employees are ‘subjects’ and the training is ‘treatment’.
• Educational institutions follow the pre-experimental research design to administer exams and evaluate students at the end of a semester. Students are the dependent variables and lectures are independent. Since exams are conducted at the end and not the beginning of a semester, it’s easy to conclude that it’s a one-shot case study research.
• To evaluate the teaching methods of two teachers, they can be assigned two student groups. After teaching their respective groups on the same topic, a posttest can determine which group scored better and who is better at teaching. This method can have its drawbacks as certain human factors, such as attitudes of students and effectiveness to grasp a subject, may negatively influence results. 

Experimental research is considered a standard method that uses observations, simulations and surveys to collect data. One of its unique features is the ability to control extraneous variables and their effects. It’s a suitable method for those looking to examine the relationship between cause and effect in a field setting or in a laboratory. Although experimental research design is a scientific approach, research is not entirely a scientific process. As much as managers need to know what is experimental research , they have to apply the correct research method, depending on the aim of the study.

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WMA Declaration of Helsinki – Ethical Principles for Medical Research Involving Human Subjects

Adopted by the 18 th WMA General Assembly, Helsinki, Finland, June 1964 and amended by the: 29 th WMA General Assembly, Tokyo, Japan, October 1975 35 th WMA General Assembly, Venice, Italy, October 1983 41 st WMA General Assembly, Hong Kong, September 1989 48 th WMA General Assembly, Somerset West, Republic of South Africa, October 1996 52 nd WMA General Assembly, Edinburgh, Scotland, October 2000 53 rd WMA General Assembly, Washington DC, USA, October 2002 (Note of Clarification added) 55 th WMA General Assembly, Tokyo, Japan, October 2004 (Note of Clarification added) 59 th WMA General Assembly, Seoul, Republic of Korea, October 2008 64 th WMA General Assembly, Fortaleza, Brazil, October 2013

1.         The World Medical Association (WMA) has developed the Declaration of Helsinki as a statement of ethical principles for medical research involving human subjects, including research on identifiable human material and data.

The Declaration is intended to be read as a whole and each of its constituent paragraphs should be applied with consideration of all other relevant paragraphs.

2.         Consistent with the mandate of the WMA, the Declaration is addressed primarily to physicians. The WMA encourages others who are involved in medical research involving human subjects to adopt these principles.

General Principles

3.         The Declaration of Geneva of the WMA binds the physician with the words, “The health of my patient will be my first consideration,” and the International Code of Medical Ethics declares that, “A physician shall act in the patient’s best interest when providing medical care.”

4.         It is the duty of the physician to promote and safeguard the health, well-being and rights of patients, including those who are involved in medical research. The physician’s knowledge and conscience are dedicated to the fulfilment of this duty.

5.         Medical progress is based on research that ultimately must include studies involving human subjects.

6.         The primary purpose of medical research involving human subjects is to understand the causes, development and effects of diseases and improve preventive, diagnostic and therapeutic interventions (methods, procedures and treatments). Even the best proven interventions must be evaluated continually through research for their safety, effectiveness, efficiency, accessibility and quality.

7.         Medical research is subject to ethical standards that promote and ensure respect for all human subjects and protect their health and rights.

8.         While the primary purpose of medical research is to generate new knowledge, this goal can never take precedence over the rights and interests of individual research subjects.

9.         It is the duty of physicians who are involved in medical research to protect the life, health, dignity, integrity, right to self-determination, privacy, and confidentiality of personal information of research subjects. The responsibility for the protection of research subjects must always rest with the physician or other health care professionals and never with the research subjects, even though they have given consent.

10.       Physicians must consider the ethical, legal and regulatory norms and standards for research involving human subjects in their own countries as well as applicable international norms and standards. No national or international ethical, legal or regulatory requirement should reduce or eliminate any of the protections for research subjects set forth in this Declaration.

11.       Medical research should be conducted in a manner that minimises possible harm to the environment.

12.       Medical research involving human subjects must be conducted only by individuals with the appropriate ethics and scientific education, training and qualifications. Research on patients or healthy volunteers requires the supervision of a competent and appropriately qualified physician or other health care professional.

13.       Groups that are underrepresented in medical research should be provided appropriate access to participation in research.

14.       Physicians who combine medical research with medical care should involve their patients in research only to the extent that this is justified by its potential preventive, diagnostic or therapeutic value and if the physician has good reason to believe that participation in the research study will not adversely affect the health of the patients who serve as research subjects.

15.       Appropriate compensation and treatment for subjects who are harmed as a result of participating in research must be ensured.

Risks, Burdens and Benefits

16.       In medical practice and in medical research, most interventions involve risks and burdens.

Medical research involving human subjects may only be conducted if the importance of the objective outweighs the risks and burdens to the research subjects.

17.       All medical research involving human subjects must be preceded by careful assessment of predictable risks and burdens to the individuals and groups involved in the research in comparison with foreseeable benefits to them and to other individuals or groups affected by the condition under investigation.

Measures to minimise the risks must be implemented. The risks must be continuously monitored, assessed and documented by the researcher.

18.       Physicians may not be involved in a research study involving human subjects unless they are confident that the risks have been adequately assessed and can be satisfactorily managed.

When the risks are found to outweigh the potential benefits or when there is conclusive proof of definitive outcomes, physicians must assess whether to continue, modify or immediately stop the study.

Vulnerable Groups and Individuals

19.       Some groups and individuals are particularly vulnerable and may have an increased likelihood of being wronged or of incurring additional harm.

All vulnerable groups and individuals should receive specifically considered protection.

20.       Medical research with a vulnerable group is only justified if the research is responsive to the health needs or priorities of this group and the research cannot be carried out in a non-vulnerable group. In addition, this group should stand to benefit from the knowledge, practices or interventions that result from the research.

Scientific Requirements and Research Protocols

21.       Medical research involving human subjects must conform to generally accepted scientific principles, be based on a thorough knowledge of the scientific literature, other relevant sources of information, and adequate laboratory and, as appropriate, animal experimentation. The welfare of animals used for research must be respected.

22.       The design and performance of each research study involving human subjects must be clearly described and justified in a research protocol.

The protocol should contain a statement of the ethical considerations involved and should indicate how the principles in this Declaration have been addressed. The protocol should include information regarding funding, sponsors, institutional affiliations, potential conflicts of interest, incentives for subjects and information regarding provisions for treating and/or compensating subjects who are harmed as a consequence of participation in the research study.

In clinical trials, the protocol must also describe appropriate arrangements for post-trial provisions.

Research Ethics Committees

23.       The research protocol must be submitted for consideration, comment, guidance and approval to the concerned research ethics committee before the study begins. This committee must be transparent in its functioning, must be independent of the researcher, the sponsor and any other undue influence and must be duly qualified. It must take into consideration the laws and regulations of the country or countries in which the research is to be performed as well as applicable international norms and standards but these must not be allowed to reduce or eliminate any of the protections for research subjects set forth in this Declaration.

The committee must have the right to monitor ongoing studies. The researcher must provide monitoring information to the committee, especially information about any serious adverse events. No amendment to the protocol may be made without consideration and approval by the committee. After the end of the study, the researchers must submit a final report to the committee containing a summary of the study’s findings and conclusions.

Privacy and C onfidentiality

24.       Every precaution must be taken to protect the privacy of research subjects and the confidentiality of their personal information.

Informed Consent

25.       Participation by individuals capable of giving informed consent as subjects in medical research must be voluntary. Although it may be appropriate to consult family members or community leaders, no individual capable of giving informed consent may be enrolled in a research study unless he or she freely agrees.

26.       In medical research involving human subjects capable of giving informed consent, each potential subject must be adequately informed of the aims, methods, sources of funding, any possible conflicts of interest, institutional affiliations of the researcher, the anticipated benefits and potential risks of the study and the discomfort it may entail, post-study provisions and any other relevant aspects of the study. The potential subject must be informed of the right to refuse to participate in the study or to withdraw consent to participate at any time without reprisal. Special attention should be given to the specific information needs of individual potential subjects as well as to the methods used to deliver the information.

After ensuring that the potential subject has understood the information, the physician or another appropriately qualified individual must then seek the potential subject’s freely-given informed consent, preferably in writing. If the consent cannot be expressed in writing, the non-written consent must be formally documented and witnessed.

All medical research subjects should be given the option of being informed about the general outcome and results of the study.

27.       When seeking informed consent for participation in a research study the physician must be particularly cautious if the potential subject is in a dependent relationship with the physician or may consent under duress. In such situations the informed consent must be sought by an appropriately qualified individual who is completely independent of this relationship.

28.       For a potential research subject who is incapable of giving informed consent, the physician must seek informed consent from the legally authorised representative. These individuals must not be included in a research study that has no likelihood of benefit for them unless it is intended to promote the health of the group represented by the potential subject, the research cannot instead be performed with persons capable of providing informed consent, and the research entails only minimal risk and minimal burden.

29.       When a potential research subject who is deemed incapable of giving informed consent is able to give assent to decisions about participation in research, the physician must seek that assent in addition to the consent of the legally authorised representative. The potential subject’s dissent should be respected.

30.       Research involving subjects who are physically or mentally incapable of giving consent, for example, unconscious patients, may be done only if the physical or mental condition that prevents giving informed consent is a necessary characteristic of the research  group. In such circumstances the physician must seek informed consent from the legally authorised representative. If no such representative is available and if the research cannot be delayed, the study may proceed without informed consent provided that the specific reasons for involving subjects with a condition that renders them unable to give informed consent have been stated in the research protocol and the study has been approved by a research ethics committee. Consent to remain in the research must be obtained as soon as possible from the subject or a legally authorised representative.

31.       The physician must fully inform the patient which aspects of their care are related to the research. The refusal of a patient to participate in a study or the patient’s decision to withdraw from the study must never adversely affect the patient-physician relationship.

32.       For medical research using identifiable human material or data, such as research on material or data contained in biobanks or similar repositories, physicians must seek informed consent for its collection, storage and/or reuse. There may be exceptional situations where consent would be impossible or impracticable to obtain for such research. In such situations the research may be done only after consideration and approval of a research ethics committee.

Use of Placebo

33.       The benefits, risks, burdens and effectiveness of a new intervention must be tested against those of the best proven intervention(s), except in the following circumstances:

Where no proven intervention exists, the use of placebo, or no intervention, is acceptable; or

Where for compelling and scientifically sound methodological reasons the use of any intervention less effective than the best proven one, the use of placebo, or no intervention is necessary to determine the efficacy or safety of an intervention

and the patients who receive any intervention less effective than the best proven one, placebo, or no intervention will not be subject to additional risks of serious or irreversible harm as a result of not receiving the best proven intervention.

Extreme care must be taken to avoid abuse of this option.

Post-Trial Provisions

34.       In advance of a clinical trial, sponsors, researchers and host country governments should make provisions for post-trial access for all participants who still need an intervention identified as beneficial in the trial. This information must also be disclosed to participants during the informed consent process.

Research Registration and Publication and Dissemination of Results

35.       Every research study involving human subjects must be registered in a publicly accessible database before recruitment of the first subject.

36.       Researchers, authors, sponsors, editors and publishers all have ethical obligations with regard to the publication and dissemination of the results of research. Researchers have a duty to make publicly available the results of their research on human subjects and are accountable for the completeness and accuracy of their reports. All parties should adhere to accepted guidelines for ethical reporting. Negative and inconclusive as well as positive results must be published or otherwise made publicly available. Sources of funding, institutional affiliations and conflicts of interest must be declared in the publication. Reports of research not in accordance with the principles of this Declaration should not be accepted for publication.

Unproven Interventions in Clinical Practice

37.       In the treatment of an individual patient, where proven interventions do not exist or other known interventions have been ineffective, the physician, after seeking expert advice, with informed consent from the patient or a legally authorised representative, may use an unproven intervention if in the physician’s judgement it offers hope of saving life, re-establishing health or alleviating suffering. This intervention should subsequently be made the object of research, designed to evaluate its safety and efficacy. In all cases, new information must be recorded and, where appropriate, made publicly available.

Policy Types

Archived versions.

• » DoH-Jun1964
• » DoH-Oct1975
• » DoH-Oct1983
• » DoH-Sept1989
• » DoH-Oct1996
• » DoH-Oct2000
• » DoH-Oct2004
• » DoH-Oct2008

Related WMA Policies

Wma declaration of venice on end of life medical care, wma international code of medical ethics.

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Supervised machine learning models rely on training datasets with positive (target class) and negative examples. Therefore, the composition of the training dataset has a direct influence on model performance. Specifically, negative sample selection bias, concerning samples not representing the target class, presents challenges across a range of domains such as text classification and protein-protein interaction prediction. Machine-learning-based immunotherapeutics design is an increasingly important area of research, focusing on designing antibodies or T-cell receptors (TCRs) that can bind to their target molecules with high specificity and affinity. Given the biomedical importance of immunotherapeutics, there is a need to address the unresolved question of how negative training set composition impacts model generalization and biological rule discovery to enable rational and safe drug design. We set out to study this question in the context of the antibody-antigen binding prediction problem by varying the negative class, encompassing a binding affinity gradient. We based our investigation on large synthetic datasets that provide ground truth structure-based antibody-antigen binding data, allowing access to residue-wise binding energy on the binding interface. We found that both out-of-distribution generalization and binding rule discovery depended on the type of negative dataset used. Importantly, we discovered that a model's capacity to learn the binding rules of the positive dataset is not a trivial correlate of its classification accuracy. We confirmed our findings with real-world relevant experimental data. Our work highlights the importance of considering training dataset composition for achieving optimal out-of-distribution performance and rule learning in machine-learning-based research.

Competing Interest Statement

V.G. declares advisory board positions in aiNET GmbH, Enpicom B.V, Absci, Omniscope, and Diagonal Therapeutics. V.G. is a consultant for Adaptive Biosystems, Specifica Inc, Roche/Genentech, immunai, LabGenius, and FairJourney Biologics.

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